PDB: 66507 件ウェブページステータス検索Chemie searchBIRD

---

4NJC	RNA Polymerase interacting protein YkzG from Geobacillus stearothermophilus 分子名称: Geobacillus stearothermophilus YkzG 著者 Keller, A.N, Lewis, P.J. 登録日 2013-11-09 公開日 2014-08-20 最終更新日 2014-10-22 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 epsilon, a New Subunit of RNA Polymerase Found in Gram-Positive Bacteria J.Bacteriol., 196, 2014
4NXZ	DNA polymerase beta with O6mG in the template base opposite to incoming non-hydrolyzable TTP with manganese in the active site 分子名称: 5'-D(*CP*CP*GP*AP*CP*(6OG)P*TP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3', 5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*A)-3', 5'-D(P*GP*TP*CP*GP*G)-3', ... 著者 Koag, M.-C, Min, K, Monzingo, A.F, Lee, S. 登録日 2013-12-09 公開日 2014-04-16 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.557 Å) 主引用文献 Metal-dependent conformational activation explains highly promutagenic replication across O6-methylguanine by human DNA polymerase beta. J.Am.Chem.Soc., 136, 2014
4NY8	DNA polymerase beta with O6mG in the template base opposite to incoming non-hydrolyzable CTP with manganese in the active site 分子名称: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]cytidine, 5'-D(*CP*CP*GP*AP*CP*(6OG)P*TP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3', 5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*A)-3', ... 著者 Koag, M.-C, Min, K, Monzingo, A.F, Lee, S. 登録日 2013-12-10 公開日 2014-04-16 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.246 Å) 主引用文献 Metal-dependent conformational activation explains highly promutagenic replication across O6-methylguanine by human DNA polymerase beta. J.Am.Chem.Soc., 136, 2014
4F0H	UNACTIVATED RUBISCO with OXYGEN BOUND 分子名称: OXYGEN MOLECULE, PHOSPHATE ION, Ribulose bisphosphate carboxylase large chain, ... 著者 Stec, B. 登録日 2012-05-04 公開日 2012-11-14 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.96 Å) 主引用文献 Structural mechanism of RuBisCO activation by carbamylation of the active site lysine. Proc.Natl.Acad.Sci.USA, 109, 2012
3EXM	Crystal structure of the phosphatase SC4828 with the non-hydrolyzable nucleotide GPCP 分子名称: CALCIUM ION, GLYCEROL, PHOSPHOMETHYLPHOSPHONIC ACID GUANOSYL ESTER, ... 著者 Singer, A.U, Xu, X, Zheng, H, Joachimiak, A, Edwards, A.M, Savchenko, A, Yakunin, A.F, Midwest Center for Structural Genomics (MCSG) 登録日 2008-10-16 公開日 2008-12-09 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Structure and mechanism of a new family of prokaryotic nucleoside diphosphatases. To be Published
4F0M	UNACTIVATED RUBISCO with MAGNESIUM AND A WATER MOLECULE BOUND 分子名称: CHLORIDE ION, GLYCEROL, MAGNESIUM ION, ... 著者 Stec, B. 登録日 2012-05-04 公開日 2012-11-14 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Structural mechanism of RuBisCO activation by carbamylation of the active site lysine. Proc.Natl.Acad.Sci.USA, 109, 2012
3OFV	Crystal structure of peptidyl-tRNA hydrolase from Escherichia Coli, I222 crystal form 分子名称: Peptidyl-tRNA hydrolase 著者 Lam, R, McGrath, T.E, Romanov, V, Gothe, S.A, Peddi, S.R, Razumova, E, Lipman, R.S, Branstrom, A.A, Chirgadze, N.Y. 登録日 2010-08-16 公開日 2011-08-17 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Crystal structure of peptidyl-tRNA hydrolase from Escherichia Coli, I222 crystal form To be Published
3OMC	Structure of human SND1 extended tudor domain in complex with the symmetrically dimethylated arginine PIWIL1 peptide R4me2s 分子名称: CHLORIDE ION, SYNTHETIC PEPTIDE, Staphylococcal nuclease domain-containing protein 1 著者 Lam, R, Liu, K, Guo, Y.H, Bian, C.B, Xu, C, MacKenzie, F, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Min, J, Structural Genomics Consortium (SGC) 登録日 2010-08-26 公開日 2010-09-15 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.77 Å) 主引用文献 Structural basis for recognition of arginine methylated Piwi proteins by the extended Tudor domain. Proc.Natl.Acad.Sci.USA, 107, 2010
3OL4	Crystal structure of a putative uncharacterized protein from Mycobacterium smegmatis, an ortholog of Rv0543c 分子名称: Putative uncharacterized protein 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2010-08-25 公開日 2010-09-08 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structural diversity in the Mycobacteria DUF3349 superfamily. Protein Sci., 29, 2020
4CM7	Crystal structure of pteridine reductase 1 (PTR1) from Trypanosoma brucei in ternary complex with cofactor and inhibitor 分子名称: 5-phenethyl-7H-pyrrolo[2,3-d]pyrimidine-2,4-diamine, ACETATE ION, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... 著者 Barrack, K.L, Hunter, W.N. 登録日 2014-01-15 公開日 2015-01-21 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structure-Based Design and Synthesis of Antiparasitic Pyrrolopyrimidines Targeting Pteridine Reductase 1. J.Med.Chem., 57, 2014
3GEN	The 1.6 A crystal structure of human bruton's tyrosine kinase bound to a pyrrolopyrimidine-containing compound 分子名称: 4-Amino-5-(4-phenoxyphenyl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl-cyclopentane, Tyrosine-protein kinase BTK 著者 Marcotte, D.J, Liu, Y.T, Arduini, R.M, Hession, C.A, Miatkowski, K, Wildes, C.P, Cullen, P.F, Hopkins, B, Mertsching, E, Jenkins, T.J, Romanowski, M.J, Baker, D.P, Silvian, L.F. 登録日 2009-02-25 公開日 2010-01-19 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Structures of human Bruton's tyrosine kinase in active and inactive conformations suggest a mechanism of activation for TEC family kinases. Protein Sci., 19, 2010
4CMB	Crystal structure of pteridine reductase 1 (PTR1) from Trypanosoma brucei in ternary complex with cofactor and inhibitor 分子名称: ACETATE ION, N4-cyclohexyl-5-(4-fluorophenyl)-7H-pyrrolo[2,3-d]pyrimidine-2,4-diamine, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... 著者 Barrack, K.L, Hunter, W.N. 登録日 2014-01-16 公開日 2015-01-21 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.96 Å) 主引用文献 Structure-Based Design and Synthesis of Antiparasitic Pyrrolopyrimidines Targeting Pteridine Reductase 1. J.Med.Chem., 57, 2014
4N3U	Candida albicans Superoxide Dismutase 5 (SOD5), Cu(II) 分子名称: CITRATE ANION, COPPER (II) ION, Potential secreted Cu/Zn superoxide dismutase 著者 Galaleldeen, A, Taylor, A.B, Waninger-Saroni, J.J, Holloway, S.P, Hart, P.J. 登録日 2013-10-07 公開日 2014-04-09 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Candida albicans SOD5 represents the prototype of an unprecedented class of Cu-only superoxide dismutases required for pathogen defense. Proc.Natl.Acad.Sci.USA, 111, 2014
4D1S	Pyrrole-3-carboxamides as potent and selective JAK2 inhibitors 分子名称: 2-(5-chloro-2-methylphenyl)-1-methyl-5-(2-{[4-(4-methylpiperazin-1-yl)phenyl]amino}pyrimidin-4-yl)-1H-pyrrole-3-carboxamide, TYROSINE-PROTEIN KINASE JAK2 著者 Bertrand, J, Canevari, G, Fasolini, M, Brasca, M.G, Nesi, M, Avanzi, N, Ballinari, D, Bandiera, T, Bindi, S, Carenzi, D, Casero, D, Ceriani, L, Ciomei, M, Cirla, A, Colombo, M, Cribioli, S, Cristiani, C, Della Vedova, F, Fachin, G, Felder, E.R, Galvani, A, Isacchi, A, Mirizzi, D, Motto, I, Panzeri, A, Pesenti, E, Vianello, P, Gnocchi, P, Donati, D. 登録日 2014-05-05 公開日 2014-07-23 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.66 Å) 主引用文献 Pyrrole-3-Carboxamides as Potent and Selective Jak2 Inhibitors. Bioorg.Med.Chem., 22, 2014
3PMT	Crystal structure of the Tudor domain of human Tudor domain-containing protein 3 分子名称: TETRAETHYLENE GLYCOL, Tudor domain-containing protein 3 著者 Lam, R, Bian, C.B, Guo, Y.H, Xu, C, Kania, J, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Min, J, Structural Genomics Consortium (SGC) 登録日 2010-11-18 公開日 2010-12-01 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Crystal Structure of TDRD3 and Methyl-Arginine Binding Characterization of TDRD3, SMN and SPF30. Plos One, 7, 2012
4N6Q	Crystal structure of VosA velvet domain 分子名称: IODIDE ION, NITRATE ION, VosA 著者 Ahmed, Y.L, Dickmanns, A, Neumann, P, Ficner, R. 登録日 2013-10-14 公開日 2014-01-22 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.79 Å) 主引用文献 The Velvet Family of Fungal Regulators Contains a DNA-Binding Domain Structurally Similar to NF-kappa B. Plos Biol., 11, 2013
3PG1	MAP kinase LmaMPK10 from Leishmania major (1.95 angs resolution) 分子名称: Mitogen-activated protein kinase, putative (Map kinase-like protein) 著者 Horjales, S, Buschiazzo, A. 登録日 2010-10-29 公開日 2011-11-16 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 The Crystal Structure of the MAP Kinase LmaMPK10 from Leishmania Major Reveals Parasite-Specific Features and Regulatory Mechanisms. Structure, 20, 2012
4CLH	Crystal structure of pteridine reductase 1 (PTR1) from Trypanosoma brucei in ternary complex with cofactor and inhibitor 分子名称: 4-thiomorpholino-7H-pyrrolo[2,3-d]pyrimidin-2-amine, ACETATE ION, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... 著者 Barrack, K.L, Hunter, W.N. 登録日 2014-01-14 公開日 2015-01-21 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Structure-Based Design and Synthesis of Antiparasitic Pyrrolopyrimidines Targeting Pteridine Reductase 1. J.Med.Chem., 57, 2014
3C2K	DNA POLYMERASE BETA with a gapped DNA substrate and DUMPNPP with Manganese in the active site 分子名称: 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE, CHLORIDE ION, DNA (5'-D(*DCP*DCP*DGP*DAP*DCP*DAP*DGP*DCP*DGP*DCP*DAP*DTP*DCP*DAP*DGP*DC)-3'), ... 著者 Batra, V.K, Beard, W.A, Shock, D.D, Pedersen, L.C, Wilson, S.H. 登録日 2008-01-25 公開日 2008-05-20 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Structures of DNA polymerase beta with active-site mismatches suggest a transient abasic site intermediate during misincorporation. Mol.Cell, 30, 2008
3OI7	Structure of the structure of the H13A mutant of Ykr043C in complex with sedoheptulose-1,7-bisphosphate 分子名称: 1,2-ETHANEDIOL, 1,7-di-O-phosphono-beta-D-altro-hept-2-ulofuranose, GLYCEROL, ... 著者 Singer, A.U, Xu, X, Dong, A, Cui, H, Clasquin, M.F, Caudy, A.A, Edwards, A.M, Savchenko, A, Joachimiak, A, Yakunin, A.F, Midwest Center for Structural Genomics (MCSG) 登録日 2010-08-18 公開日 2010-11-17 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Riboneogenesis in yeast. Cell(Cambridge,Mass.), 145, 2011
3OJ6	Crystal structure of Blasticidin S Deaminase from Coccidioides Immitis 分子名称: 1,2-ETHANEDIOL, Blasticidin-S deaminase, CHLORIDE ION, ... 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2010-08-20 公開日 2010-09-15 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Crystal structure of Blasticidin S Deaminase from Coccidioides Immitis To be Published
4MR1	X-ray structure of the adduct between hen egg white lysozyme and cis-diamminediiodoplatinum(II) 分子名称: CHLORIDE ION, Lysozyme C, SODIUM ION, ... 著者 Merlino, A. 登録日 2013-09-17 公開日 2014-06-04 実験手法 X-RAY DIFFRACTION (1.99 Å) 主引用文献 Peculiar features in the crystal structure of the adduct formed between cis-PtI2(NH3)2 and hen egg white lysozyme. Inorg.Chem., 52, 2013
4CM8	Crystal structure of pteridine reductase 1 (PTR1) from Trypanosoma brucei in ternary complex with cofactor and inhibitor 分子名称: (E)-2,4-diamino-6-(4-methylstyryl)-7H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile, 2,3-DIHYDROXY-1,4-DITHIOBUTANE, ACETATE ION, ... 著者 Barrack, K.L, Hunter, W.N. 登録日 2014-01-15 公開日 2015-01-21 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structure-Based Design and Synthesis of Antiparasitic Pyrrolopyrimidines Targeting Pteridine Reductase 1. J.Med.Chem., 57, 2014
4CLE	Crystal structure of pteridine reductase 1 (PTR1) from Trypanosoma brucei in ternary complex with cofactor and inhibitor 分子名称: 4-(pyrrolidin-1-yl)-7H-pyrrolo[2,3-d]pyrimidin-2-amine, DITHIANE DIOL, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... 著者 Barrack, K.L, Hunter, W.N. 登録日 2014-01-14 公開日 2015-01-21 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structure-Based Design and Synthesis of Antiparasitic Pyrrolopyrimidines Targeting Pteridine Reductase 1. J.Med.Chem., 57, 2014
3PGG	Crystal structure of cryptosporidium parvum u6 snrna-associated sm-like protein lsm5 分子名称: U6 snRNA-associated Sm-like protein LSm5. SM domain 著者 Dong, A, Gao, M, Zhao, Y, Lew, J, Wasney, G.A, Kozieradzki, I, Vedadi, M, Edwards, A, Arrowsmith, C, Weigelt, J, Sundstrom, M, Bochkarev, A, Hui, R, Artz, J, Structural Genomics Consortium (SGC) 登録日 2010-11-01 公開日 2011-02-02 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.14 Å) 主引用文献 Genome-Scale Protein Expression and Structural Biology of Plasmodium Falciparum and Related Apicomplexan Organisms. Mol.Biochem.Parasitol., 151, 2007

<391392393394395396397398399400401402403404405406>