PDB: 30476 件ウェブページステータス検索Chemie searchBIRD

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5WMS	Phosphotriesterase variant S7 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, CACODYLATE ION, Phosphotriesterase, ... 著者 Miton, C.M, Campbell, E.C, Jackson, C.J, Tokuriki, N. 登録日 2017-07-31 公開日 2019-01-23 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Phosphotriesterase variant S7 To Be Published
4X6B	BK6 TCR apo structure 分子名称: TCR alpha, TCR beta 著者 Birkinshaw, R.W, Rossjohn, J. 登録日 2014-12-07 公開日 2015-01-28 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 alpha beta T cell antigen receptor recognition of CD1a presenting self lipid ligands. Nat.Immunol., 16, 2015
5Z8Z	BRD4 Bromodomain 1 with an inhibitor 分子名称: 6-[(3S)-3-azanylpiperidin-1-yl]sulfonyl-1-ethyl-benzo[cd]indol-2-one, Bromodomain-containing protein 4 著者 Xiao, S, Chen, S, Chen, H. 登録日 2018-02-01 公開日 2019-02-06 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 BRD4 Bromodomain 1 with an inhibitor To Be Published
4X8E	Ergothioneine-biosynthetic sulfoxide synthase EgtB in complex with N,N,N-trimethyl-histidine 分子名称: CALCIUM ION, CHLORIDE ION, FE (III) ION, ... 著者 Vit, A, Goncharenko, K.V, Blankenfeldt, W, Seebeck, F.P. 登録日 2014-12-10 公開日 2015-01-28 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Structure of the Sulfoxide Synthase EgtB from the Ergothioneine Biosynthetic Pathway. Angew.Chem.Int.Ed.Engl., 54, 2015
5Z99	Crystal structure of Sialic acid Binding protein from Haemophilus ducreyi with Neu5Ac 分子名称: N-acetyl-beta-neuraminic acid, Putative ABC transporter periplasmic binding protein 著者 Subramanian, R, Setty, T.G. 登録日 2018-02-02 公開日 2018-10-24 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.494 Å) 主引用文献 Molecular characterization of the interaction of sialic acid with the periplasmic binding protein fromHaemophilus ducreyi. J. Biol. Chem., 293, 2018
4X7R	Crystal structure of S. aureus TarM G117R mutant in complex with Fondaparinux, alpha-GlcNAc-glycerol and UDP 分子名称: (2S)-2,3-dihydroxypropyl 2-acetamido-2-deoxy-alpha-D-glucopyranoside, 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-beta-D-glucopyranuronic acid-(1-4)-2-deoxy-3,6-di-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-methyl 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranoside, TarM, ... 著者 Worrall, L.J, Sobhanifar, S, Strynadka, N.C. 登録日 2014-12-09 公開日 2015-02-25 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Structure and mechanism of Staphylococcus aureus TarM, the wall teichoic acid alpha-glycosyltransferase. Proc.Natl.Acad.Sci.USA, 112, 2015
4X86	Crystal structure of BAG6-Ubl4a complex 分子名称: 3-[(3-CHOLAMIDOPROPYL)DIMETHYLAMMONIO]-1-PROPANESULFONATE, Large proline-rich protein BAG6, SULFATE ION, ... 著者 Kuwabara, N, Kato, R. 登録日 2014-12-10 公開日 2015-02-25 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Structure of a BAG6 (Bcl-2-associated Athanogene 6)-Ubl4a (Ubiquitin-like Protein 4a) Complex Reveals a Novel Binding Interface That Functions in Tail-anchored Protein Biogenesis J.Biol.Chem., 290, 2015
4X8C	Crystal structure of human peptidylarginine deiminase type4 (PAD4) in complex with GSK147 分子名称: CALCIUM ION, Protein-arginine deiminase type-4, [(3S,4R)-3-amino-4-hydroxypiperidin-1-yl]{2-[1-(cyclopropylmethyl)-1H-pyrrolo[2,3-b]pyridin-2-yl]-7-methoxy-1-methyl-1H-benzimidazol-5-yl}methanone 著者 Lewis, H.D, Bax, B.D, Chung, C.-W, Polyakova, O, Thorpe, J. 登録日 2014-12-10 公開日 2015-01-28 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Inhibition of PAD4 activity is sufficient to disrupt mouse and human NET formation. Nat.Chem.Biol., 11, 2015
4X8I	de novo crystal structure of the Pyrococcus Furiosus TET3 aminopeptidase 分子名称: 10-((2R)-2-HYDROXYPROPYL)-1,4,7,10-TETRAAZACYCLODODECANE 1,4,7-TRIACETIC ACID, CHLORIDE ION, COBALT (II) ION, ... 著者 Colombo, M. 登録日 2014-12-10 公開日 2016-02-10 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Tuned by metals: the TET peptidase activity is controlled by 3 metal binding sites. Sci Rep, 6, 2016
4Y5X	Diabody 305 complex with EpoR 分子名称: CITRATE ANION, DI(HYDROXYETHYL)ETHER, Erythropoietin receptor, ... 著者 Moraga, I, Guo, F, Ozkan, E, Jude, K.M, Garcia, K.C. 登録日 2015-02-12 公開日 2015-03-18 最終更新日 2017-11-22 実験手法 X-RAY DIFFRACTION (3.15 Å) 主引用文献 Tuning Cytokine Receptor Signaling by Re-orienting Dimer Geometry with Surrogate Ligands. Cell, 160, 2015
5ZG4	Crystal Structure of Triosephosphate isomerase SAD deletion mutant from Opisthorchis viverrini 分子名称: Triosephosphate isomerase 著者 Son, J, Kim, S, Kim, S.E, Lee, H, Lee, M.R, Hwang, K.Y. 登録日 2018-03-07 公開日 2018-10-24 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.746 Å) 主引用文献 Structural Analysis of an Epitope Candidate of Triosephosphate Isomerase in Opisthorchis viverrini. Sci Rep, 8, 2018
5ZLN	Crystal structure of mouse TLR9 in complex with two DNAs (CpG DNA and TCGCCA DNA) 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, DNA (5'-D(*AP*GP*GP*CP*GP*TP*TP*TP*TP*T)-3'), ... 著者 Ishida, H, Ohto, U, Shimizu, T. 登録日 2018-03-28 公開日 2018-04-25 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structural basis for species-specific activation of mouse Toll-like receptor 9 FEBS Lett., 592, 2018
4YBV	Crystal Structure of mutant of (Q32A) thioesterase enzyme SAV0944 from Staphylococcus aureus subsp. aureus Mu50 分子名称: Uncharacterized protein 著者 Khandokar, Y.B, Srivastava, P, Forwood, J. 登録日 2015-02-19 公開日 2016-02-10 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Crystal Structure of mutant of (Q32A) hypothetical protein SAV0944 from Staphylococcus aureus subsp. aureus Mu50 To Be Published
5ZJB	Structure of N-acetylmannosamine-6-phosphate-2-epimerase from Vibrio cholerae 分子名称: DI(HYDROXYETHYL)ETHER, MALONATE ION, Putative N-acetylmannosamine-6-phosphate 2-epimerase 著者 Manjunath, L, Guntupalli, S. 登録日 2018-03-19 公開日 2018-09-19 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.699 Å) 主引用文献 Crystal structures and kinetic analyses of N-acetylmannosamine-6-phosphate 2-epimerases from Fusobacterium nucleatum and Vibrio cholerae Acta Crystallogr F Struct Biol Commun, 74, 2018
4YEJ	Tailspike protein double mutant D339A/E372Q of E. coli bacteriophage HK620 in complex with pentasaccharide 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, FORMIC ACID, SODIUM ION, ... 著者 Gohlke, U, Broeker, N.K, Heinemann, U, Seckler, R, Barbirz, S. 登録日 2015-02-24 公開日 2016-03-09 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Enthalpic cost of water removal from a hydrophobic glucose binding cavity on HK620 tailspike protein. to be published
5ZJQ	Structure of AbdB/Exd complex bound to a 'Red14' DNA sequence 分子名称: DNA (5'-D(*GP*CP*AP*TP*GP*AP*TP*TP*TP*AP*TP*GP*AP*C)-3'), DNA (5'-D(*GP*TP*CP*AP*TP*AP*AP*AP*TP*CP*AP*TP*GP*C)-3'), Homeobox protein abdominal-B, ... 著者 Baburajendran, N, Zeiske, T, Kaczynska, A, Mann, R, Honig, B, Shapiro, L, Palmer, A.G. 登録日 2018-03-22 公開日 2018-08-29 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.443 Å) 主引用文献 Intrinsic DNA Shape Accounts for Affinity Differences between Hox-Cofactor Binding Sites. Cell Rep, 24, 2018
5ZKN	Structure of N-acetylmannosamine-6-phosphate 2-epimerase from Fusobacterium nucleatum 分子名称: CHLORIDE ION, Putative N-acetylmannosamine-6-phosphate 2-epimerase 著者 Manjunath, L. 登録日 2018-03-24 公開日 2018-09-19 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (2.205 Å) 主引用文献 Crystal structures and kinetic analyses of N-acetylmannosamine-6-phosphate 2-epimerases from Fusobacterium nucleatum and Vibrio cholerae Acta Crystallogr F Struct Biol Commun, 74, 2018
5ZMA	Structural basis for an allosteric Eya2 phosphatase inhibitor 分子名称: 3-fluoro-N'-[(E)-{5-[(pyrimidin-2-yl)sulfanyl]furan-2-yl}methylidene]benzohydrazide, Eyes absent homolog 2 著者 Anantharajan, J, Jansson, A.E, Kang, C. 登録日 2018-04-02 公開日 2019-06-05 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (3.175 Å) 主引用文献 Structural and Functional Analyses of an Allosteric EYA2 Phosphatase Inhibitor That Has On-Target Effects in Human Lung Cancer Cells. Mol.Cancer Ther., 18, 2019
5ZLV	DNA polymerase IV - DNA ternary complex with 50mM MgCl2 分子名称: DIPHOSPHATE, DNA polymerase IV, DTN1, ... 著者 Kottur, J, Nair, D.T. 登録日 2018-03-29 公開日 2018-11-07 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 Pyrophosphate hydrolysis is an intrinsic and critical step of the DNA synthesis reaction Nucleic Acids Res., 46, 2018
5ZMS	Crystal structure of Zika NS3 protease in complex with 4-guanidinomethyl-phenylacetyl-Lys-Lys-Arg-H 分子名称: 4-guanidinomethyl-phenylacetyl-Lys-Lys-Arg-H, NS3 protease, Serine protease subunit NS2B 著者 Phoo, W.W, Wirawan, M. 登録日 2018-04-05 公開日 2018-10-17 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structures of Zika virus NS2B-NS3 protease in complex with peptidomimetic inhibitors. Antiviral Res., 160, 2018
5ZNI	Plasmodium falciparum purine nucleoside phosphorylase in complex with mefloquine 分子名称: Mefloquine, PHOSPHATE ION, Purine nucleoside phosphorylase 著者 Chen, D, Nordlund, P, Dziekan, J.M. 登録日 2018-04-09 公開日 2019-01-16 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Identifying purine nucleoside phosphorylase as the target of quinine using cellular thermal shift assay. Sci Transl Med, 11, 2019
5ZNK	Crystal structure of a bacterial ProRS with ligands 分子名称: 7-chloro-6-fluoro-3-{2-oxo-3-[(2S)-piperidin-2-yl]propyl}quinazolin-4(3H)-one, GLYCEROL, MAGNESIUM ION, ... 著者 Cheng, B, Yu, Y, Zhou, H. 登録日 2018-04-09 公開日 2019-05-29 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.07 Å) 主引用文献 Structure-Guided Design of Halofuginone Derivatives as ATP-Aided Inhibitors Against Bacterial Prolyl-tRNA Synthetase. J.Med.Chem., 65, 2022
4YR1	Crystal Structure of E. Coli Alkaline Phosphatase D101A/D153A in complex with inorganic phosphate 分子名称: Alkaline phosphatase, GLYCEROL, PHOSPHATE ION, ... 著者 Peck, A, Herschlag, D. 登録日 2015-03-13 公開日 2015-04-29 最終更新日 2019-12-25 実験手法 X-RAY DIFFRACTION (2.24 Å) 主引用文献 Extensive site-directed mutagenesis reveals interconnected functional units in the Alkaline Phosphatase active site. Elife, 4, 2015
4YRI	Crystal structure of T. cruzi Histidyl-tRNA synthetase in complex with 1-(3-bromophenyl)methanamine (Chem 166) 分子名称: 1,2-ETHANEDIOL, 1-(3-bromophenyl)methanamine, DIMETHYL SULFOXIDE, ... 著者 Koh, C.-Y, Hol, W.G.J. 登録日 2015-03-15 公開日 2015-08-12 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 A binding hotspot in Trypanosoma cruzi histidyl-tRNA synthetase revealed by fragment-based crystallographic cocktail screens. Acta Crystallogr. D Biol. Crystallogr., 71, 2015
4YRR	Crystal structure of T. cruzi Histidyl-tRNA synthetase in complex with N-(quinolin-3-yl)acetamide (Chem 1691) 分子名称: 1,2-ETHANEDIOL, DIMETHYL SULFOXIDE, HISTIDINE, ... 著者 Koh, C.-Y, Hol, W.G.J. 登録日 2015-03-15 公開日 2015-08-12 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 A binding hotspot in Trypanosoma cruzi histidyl-tRNA synthetase revealed by fragment-based crystallographic cocktail screens. Acta Crystallogr. D Biol. Crystallogr., 71, 2015

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