PDB: 222624 件ウェブページステータス検索Chemie searchBIRD

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4I93	Structure of the BSK8 kinase domain (SeMet labeled) 分子名称: Probable serine/threonine-protein kinase At5g41260 著者 Gruetter, C, Rauh, D. 登録日 2012-12-04 公開日 2013-08-14 最終更新日 2013-11-20 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Structural Characterization of the RLCK Family Member BSK8: A Pseudokinase with an Unprecedented Architecture J.Mol.Biol., 425, 2013
4MU6	Crystal Structure of the N-terminal domain of Effector Protein LegC3 from Legionella pneumophila 分子名称: Kinectin 1 (Kinesin receptor) 著者 Yao, D, Cherney, M, Cygler, M. 登録日 2013-09-20 公開日 2013-12-11 最終更新日 2017-11-15 実験手法 X-RAY DIFFRACTION (2.082 Å) 主引用文献 Structure of the N-terminal domain of the effector protein LegC3 from Legionella pneumophila. Acta Crystallogr.,Sect.D, 70, 2014
3NRR	Co-crystal structure of dihydrofolate reductase-thymidylate synthase from Babesia bovis with dUMP, Raltitrexed and NADP 分子名称: 1,2-ETHANEDIOL, 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, CHLORIDE ION, ... 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2010-06-30 公開日 2010-07-14 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Inhibitor-bound complexes of dihydrofolate reductase-thymidylate synthase from Babesia bovis. Acta Crystallogr.,Sect.F, 67, 2011
4IAA	Crystal structure of Ser/Thr kinase Pim1 in complex with thioridazine 分子名称: 10-{2-[(2R)-1-methylpiperidin-2-yl]ethyl}-2-(methylsulfanyl)-10H-phenothiazine, Serine/threonine-protein kinase pim-1 著者 Zhang, W, Wan, X, Li, W, Xie, Y, Huang, N. 登録日 2012-12-06 公開日 2013-12-18 実験手法 X-RAY DIFFRACTION (2.85 Å) 主引用文献 Crystal structure of Ser/Thr kinase Pim1 in complex with thioridazine To be Published
4KY1	humanized HP1/2 Fab 分子名称: IMMUNOGLOBULIN IGG1 FAB, HEAVY CHAIN, LIGHT CHAIN 著者 Arndt, J.W, Hanf, K.J.M, Lugovskoy, A, Chen, L.L, Jarpe, M, Boriack-Sjodin, A, Li, Y, van Vlijmen, H, Pepinsky, B, Taylor, F, Silvian, L, Taveras, A. 登録日 2013-05-28 公開日 2013-07-24 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.97 Å) 主引用文献 Antibody humanization by redesign of complementarity-determining region residues proximate to the acceptor framework. METHODS (SAN DIEGO), 65, 2014
3EUJ	Crystal structure of MukE-MukF(residues 292-443)-MukB(head domain)-ATPgammaS complex, symmetric dimer 分子名称: Chromosome partition protein mukB, Linker, Chromosome partition protein mukF, ... 著者 Woo, J.S, Lim, J.H, Shin, H.C, Oh, B.H. 登録日 2008-10-10 公開日 2009-01-20 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Structural studies of a bacterial condensin complex reveal ATP-dependent disruption of intersubunit interactions. Cell(Cambridge,Mass.), 136, 2009
4IAN	Crystal Structure of apo Human PRPF4B kinase domain 分子名称: SULFATE ION, Serine/threonine-protein kinase PRP4 homolog 著者 Mechin, I, Haas, K, Chen, X, Zhang, Y, McLean, L. 登録日 2012-12-06 公開日 2013-08-28 最終更新日 2017-11-15 実験手法 X-RAY DIFFRACTION (2.44 Å) 主引用文献 Evaluation of Cancer Dependence and Druggability of PRP4 Kinase Using Cellular, Biochemical, and Structural Approaches. J.Biol.Chem., 288, 2013
3NTS	Catalytic domain of VsdC from Aeromonas hydrophila 分子名称: SULFATE ION, VsdC 著者 Pfoh, R, Shniffer, A, Merrill, A.R, Pai, E.F. 登録日 2010-07-05 公開日 2011-06-22 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (3.4 Å) 主引用文献 Biochemical characterization of an actin-targeting ADP ribosyltransferase from aeromonas hydrophila and the identification of a novel inhibitor for this toxin family To be Published
4LHF	Crystal structure of a DNA binding protein from phage P2 分子名称: Regulatory protein cox 著者 Berntsson, R.P.-A, Odegrip, R, Sehlen, W, Skaar, K, Svensson, L.M, Massad, T, Haggard-Ljungquist, E, Stenmark, P. 登録日 2013-07-01 公開日 2014-03-05 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.401 Å) 主引用文献 Structural insight into DNA binding and oligomerization of the multifunctional Cox protein of bacteriophage P2. Nucleic Acids Res., 42, 2014
3E8E	Crystal structures of the kinase domain of PKA in complex with ATP-competitive inhibitors 分子名称: 4-[2-(4-amino-2,5-dihydro-1,2,5-oxadiazol-3-yl)-6-{[(1S)-3-amino-1-phenylpropyl]oxy}-1-ethyl-1H-imidazo[4,5-c]pyridin-4-yl]-2-methylbut-3-yn-2-ol, PKI inhibitor peptide, cAMP-dependent protein kinase catalytic subunit alpha 著者 Concha, N.O, Elkins, P.A, Smallwood, A, Ward, P. 登録日 2008-08-19 公開日 2008-11-18 最終更新日 2017-10-25 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Aminofurazans as potent inhibitors of AKT kinase Bioorg.Med.Chem.Lett., 19, 2009
4I26	2.20 Angstroms X-ray crystal structure of 2-aminomuconate 6-semialdehyde dehydrogenase from Pseudomonas fluorescens 分子名称: 1,2-ETHANEDIOL, 2-aminomuconate 6-semialdehyde dehydrogenase, SODIUM ION 著者 Davis, I, Huo, L, Chen, L, Liu, A. 登録日 2012-11-21 公開日 2014-05-21 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.204 Å) 主引用文献 Crystallographic and spectroscopic snapshots reveal a dehydrogenase in action. Nat Commun, 6, 2015
4L43	Crystal structures of human p70S6K1-T389A (form I) 分子名称: 2-{[4-(5-ethylpyrimidin-4-yl)piperazin-1-yl]methyl}-5-(trifluoromethyl)-1H-benzimidazole, RPS6KB1 protein 著者 Wang, J, Zhong, C, Ding, J. 登録日 2013-06-07 公開日 2013-07-24 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Crystal structures of S6K1 provide insights into the regulation mechanism of S6K1 by the hydrophobic motif Biochem.J., 454, 2013
4KXY	Human transketolase in complex with ThDP analogue (R)-2-(1,2-dihydroxyethyl)-3-deaza-ThDP 分子名称: 1,2-ETHANEDIOL, 2-{4-[(4-amino-2-methylpyrimidin-5-yl)methyl]-5-[(1R)-1,2-dihydroxyethyl]-3-methylthiophen-2-yl}ethyl trihydrogen diphosphate, CALCIUM ION, ... 著者 Neumann, P, Luedtke, S, Erixon, K.M, Leeper, F, Kluger, R, Ficner, R, Tittmann, K. 登録日 2013-05-28 公開日 2013-08-21 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.26 Å) 主引用文献 Sub-angstrom-resolution crystallography reveals physical distortions that enhance reactivity of a covalent enzymatic intermediate. Nat Chem, 5, 2013
4KZ3	Crystal structure of AmpC beta-lactamase in complex with fragment 44 (5-chloro-3-sulfamoylthiophene-2-carboxylic acid) 分子名称: 5-chloro-3-sulfamoylthiophene-2-carboxylic acid, Beta-lactamase, PHOSPHATE ION 著者 Eidam, O, Barelier, S, Fish, I, Shoichet, B.K. 登録日 2013-05-29 公開日 2014-05-21 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.67 Å) 主引用文献 Increasing chemical space coverage by combining empirical and computational fragment screens. Acs Chem.Biol., 9, 2014
4KZI	Crystal Structure of TR3 LBD in complex with DPDO 分子名称: 1-(3,5-dimethoxyphenyl)decan-1-one, GLYCEROL, Nuclear receptor subfamily 4 group A member 1 著者 Li, F, Zhang, Q, Li, A, Tian, X, Cai, Q, Wang, W, Wang, Y, Chen, H, Xing, Y, Wu, Q, Lin, T. 登録日 2013-05-30 公開日 2013-12-18 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.41 Å) 主引用文献 Orphan nuclear receptor TR3 acts in autophagic cell death via mitochondrial signaling pathway. Nat.Chem.Biol., 10, 2014
3O2N	X-ray Crystallographic Structure Activity Relationship (SAR) of Casimiroin and its Analogs Bound to Human Quinone Reductase 2 分子名称: 5,8-dimethoxy-4-methylquinolin-2(1H)-one, FLAVIN-ADENINE DINUCLEOTIDE, Ribosyldihydronicotinamide dehydrogenase [quinone], ... 著者 Sturdy, M. 登録日 2010-07-22 公開日 2011-08-03 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 X-ray Crystallographic Structure Activity Relationship (SAR) of Casimiroin and its Analogs Bound to Human Quinone Reductase 2 To be Published
4HZA	Crystal Structure of the Immunoglobulin variable domain of Nectin-2 in monoclinic form 分子名称: Poliovirus receptor-related protein 2 著者 Ramagopal, U.A, Samanta, D, Nathenson, S.G, Almo, S.C, New York Structural Genomics Research Consortium (NYSGRC), Atoms-to-Animals: The Immune Function Network (IFN) 登録日 2012-11-14 公開日 2013-01-30 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Crystal Structure of the Immunoglobulin variable domain of Nectin-2 in monoclinic form To be published
3ED9	Carbonmonoxy Sperm Whale Myoglobin at 140 K: Laser on [30 min] 分子名称: CARBON MONOXIDE, Myoglobin, PROTOPORPHYRIN IX CONTAINING FE, ... 著者 Tomita, A, Sato, T, Ichiyanagi, K, Nozawa, S, Ichikawa, H, Chollet, M, Kawai, F, Park, S.-Y, Koshihara, S, Adachi, S. 登録日 2008-09-02 公開日 2009-02-24 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.21 Å) 主引用文献 Visualizing breathing motion of internal cavities in concert with ligand migration in myoglobin. Proc.Natl.Acad.Sci.USA, 106, 2009
3EEL	Candida glabrata Dihydrofolate Reductase complexed with 2,4-diamino-5-[3-methyl-3-(3-methoxy-5-(3,5-dimethylphenyl)phenyl)prop-1-ynyl]-6-methylpyrimidine(UCP11153TM) and NADPH 分子名称: 5-[(3R)-3-(5-methoxy-3',5'-dimethylbiphenyl-3-yl)but-1-yn-1-yl]-6-methylpyrimidine-2,4-diamine, Dihydrofolate reductase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE 著者 Liu, J, Anderson, A. 登録日 2008-09-04 公開日 2009-08-18 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Probing the active site of Candida glabrata dihydrofolate reductase with high resolution crystal structures and the synthesis of new inhibitors Chem.Biol.Drug Des., 73, 2009
3O5V	The Crystal Structure of the Creatinase/Prolidase N-terminal domain of an X-PRO dipeptidase from Streptococcus pyogenes to 1.85A 分子名称: CHLORIDE ION, GLYCEROL, X-PRO dipeptidase 著者 Stein, A.J, Wu, R, Clancy, S, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) 登録日 2010-07-28 公開日 2010-08-11 最終更新日 2017-11-08 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 The Crystal Structure of the Creatinase/Prolidase N-terminal domain of an X-PRO dipeptidase from Streptococcus pyogenes to 1.85A To be Published
3EDM	Crystal structure of a short chain dehydrogenase from Agrobacterium tumefaciens 分子名称: Short chain dehydrogenase 著者 Bonanno, J.B, Rutter, M, Bain, K.T, Chang, S, Romero, R, Wasserman, S, Sauder, J.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC) 登録日 2008-09-03 公開日 2008-09-30 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Crystal structure of a short chain dehydrogenase from Agrobacterium tumefaciens To be Published
3EDW	Replacement of Val3 in Human Thymidylate Synthase Affects Its Kinetic Properties and Intracellular Stability 分子名称: SULFATE ION, Thymidylate synthase 著者 Huang, X, Gibson, L.M, Bell, B.J, Lovelace, L.L, Pena, M.M, Berger, F.G, Berger, S.H. 登録日 2008-09-03 公開日 2010-03-02 最終更新日 2021-10-20 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Replacement of Val3 in human thymidylate synthase affects its kinetic properties and intracellular stability . Biochemistry, 49, 2010
3O6Z	Structure of the D152A E.coli GDP-mannose hydrolase (yffh) in complex with Mg++ 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... 著者 Amzel, L.M, Gabelli, S.B, Boto, A.N. 登録日 2010-07-29 公開日 2011-05-11 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Structural studies of the Nudix GDP-mannose hydrolase from E. coli reveals a new motif for mannose recognition. Proteins, 79, 2011
3EGO	Crystal structure of Probable 2-dehydropantoate 2-reductase panE from Bacillus Subtilis 分子名称: Probable 2-dehydropantoate 2-reductase 著者 Ramagopal, U.A, Toro, R, Gilmore, M, Hu, S, Maletic, M, Gheyi, T, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC) 登録日 2008-09-11 公開日 2008-09-30 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Crystal structure of Probable 2-dehydropantoate 2-reductase panE from Bacillus Subtilis To be published
4LAN	Crystal structure of Cordyceps militaris IDCase H195A mutant 分子名称: Uracil-5-carboxylate decarboxylase, ZINC ION 著者 Xu, S, Li, W, Zhu, J, Ding, J. 登録日 2013-06-20 公開日 2013-10-02 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Crystal structures of isoorotate decarboxylases reveal a novel catalytic mechanism of 5-carboxyl-uracil decarboxylation and shed light on the search for DNA decarboxylase. Cell Res., 23, 2013

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