4IAA
Crystal structure of Ser/Thr kinase Pim1 in complex with thioridazine
Summary for 4IAA
Entry DOI | 10.2210/pdb4iaa/pdb |
Descriptor | Serine/threonine-protein kinase pim-1, 10-{2-[(2R)-1-methylpiperidin-2-yl]ethyl}-2-(methylsulfanyl)-10H-phenothiazine (3 entities in total) |
Functional Keywords | pim1 kinase/oncogene/thioridazine, ser/thr kinase, thioridazine, transferase |
Biological source | Homo sapiens (human) |
Cellular location | Isoform 2: Cytoplasm. Isoform 1: Cell membrane: P11309 |
Total number of polymer chains | 1 |
Total formula weight | 33663.29 |
Authors | |
Primary citation | Zhang, W.,Wan, X.,Li, W.,Xie, Y.,Huang, N. Crystal structure of Ser/Thr kinase Pim1 in complex with thioridazine To be Published, |
Experimental method | X-RAY DIFFRACTION (2.85 Å) |
Structure validation
Download full validation report