4IAA
Crystal structure of Ser/Thr kinase Pim1 in complex with thioridazine
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Serine/threonine-protein kinase pim-1 | polymer | 289 | 33292.7 | 1 | UniProt (P11309) Pfam (PF00069) | Homo sapiens (human) | |
| 2 | B (A) | 10-{2-[(2R)-1-methylpiperidin-2-yl]ethyl}-2-(methylsulfanyl)-10H-phenothiazine | non-polymer | 370.6 | 1 | Chemie (RTZ) | |||
| 3 | C (A) | water | water | 18.0 | 5 | Chemie (HOH) |
Sequence modifications
A: 29 - 313 (UniProt: P11309)
| PDB | External Database | Details |
|---|---|---|
| Gly 25 | - | expression tag |
| Pro 26 | - | expression tag |
| His 27 | - | expression tag |
| Met 28 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 33292.7 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 370.6 | |
| All* | Total formula weight | 33663.3 |
