4KY1

humanized HP1/2 Fab

Summary for 4KY1

• Entry DOI: 10.2210/pdb4ky1/pdb
• Descriptor: IMMUNOGLOBULIN IGG1 FAB, LIGHT CHAIN, IMMUNOGLOBULIN IGG1 FAB, HEAVY CHAIN (2 entities in total)
• Functional Keywords: fab, antibody, alpha4 integrin, immune system
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 2
• Total formula weight: 46745.06

Authors

Arndt, J.W.,Hanf, K.J.M.,Lugovskoy, A.,Chen, L.L.,Jarpe, M.,Boriack-Sjodin, A.,Li, Y.,van Vlijmen, H.,Pepinsky, B.,Taylor, F.,Silvian, L.,Taveras, A. (deposition date: 2013-05-28, release date: 2013-07-24, Last modification date: 2023-09-20)

• Primary citation: Hanf, K.J.,Arndt, J.W.,Chen, L.L.,Jarpe, M.,Boriack-Sjodin, P.A.,Li, Y.,van Vlijmen, H.W.,Pepinsky, R.B.,Simon, K.J.,Lugovskoy, A.; Antibody humanization by redesign of complementarity-determining region residues proximate to the acceptor framework.; METHODS (SAN DIEGO), 65:68-76, 2014; PubMed: 23816785; DOI: 10.1016/j.ymeth.2013.06.024

Experimental method

X-RAY DIFFRACTION (2.97 Å)