PDB: 10970 件ウェブページステータス検索Chemie searchBIRD

---

2LVG	NMR structure of HCV Non-structural protein AB, NS4B(1-40) 分子名称: Non-structural protein 4B 著者 Montserret, R, Penin, F. 登録日 2012-07-05 公開日 2013-06-19 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Aminoterminal Amphipathic alpha-Helix AH1 of Hepatitis C Virus Nonstructural Protein 4B Possesses a Dual Role in RNA Replication and Virus Production. Plos Pathog., 10, 2014
7BVC	Cryo-EM structure of Mycobacterium smegmatis arabinosyltransferase EmbA-EmbB-AcpM2 in complex with ethambutol 分子名称: 4'-PHOSPHOPANTETHEINE, CALCIUM ION, CARDIOLIPIN, ... 著者 Zhang, L, Zhao, Y, Gao, Y, Wang, Q, Li, J, Besra, G.S, Rao, Z. 登録日 2020-04-10 公開日 2020-04-29 最終更新日 2020-07-01 実験手法 ELECTRON MICROSCOPY (2.9 Å) 主引用文献 Structures of cell wall arabinosyltransferases with the anti-tuberculosis drug ethambutol. Science, 368, 2020
7BVF	Cryo-EM structure of Mycobacterium tuberculosis arabinosyltransferase EmbA-EmbB-AcpM2 in complex with ethambutol 分子名称: CALCIUM ION, CARDIOLIPIN, Ethambutol, ... 著者 Zhang, L, Zhao, Y, Gao, Y, Wang, Q, Li, J, Besra, G.S, Rao, Z. 登録日 2020-04-10 公開日 2020-04-29 最終更新日 2024-03-27 実験手法 ELECTRON MICROSCOPY (2.97 Å) 主引用文献 Structures of cell wall arabinosyltransferases with the anti-tuberculosis drug ethambutol. Science, 368, 2020
5G0T	InhA in complex with a DNA encoded library hit 分子名称: 1-benzyl-N-[cis-4-(2-{[(4-fluorophenyl)methyl][2-(methylamino)-2-oxoethyl]amino}-2-oxoethyl)cyclohexyl]-5-methyl-1H-1,2,3-triazole-4-carboxamide, ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE [NADH], NICOTINAMIDE-ADENINE-DINUCLEOTIDE 著者 Read, J.A, Breed, J. 登録日 2016-03-22 公開日 2016-11-30 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.54 Å) 主引用文献 Discovery of Cofactor-Specific, Bactericidal Mycobacterium Tuberculosis Inha Inhibitors Using DNA-Encoded Library Technology Proc.Natl.Acad.Sci.USA, 113, 2016
3O38	Crystal structure of a short chain dehydrogenase from Mycobacterium smegmatis 分子名称: SODIUM ION, Short chain dehydrogenase 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2010-07-23 公開日 2010-08-11 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Increasing the structural coverage of tuberculosis drug targets. Tuberculosis (Edinb), 95, 2015
7BVE	Cryo-EM structure of Mycobacterium smegmatis arabinosyltransferase EmbC2-AcpM2 in complex with ethambutol 分子名称: CALCIUM ION, Ethambutol, Integral membrane indolylacetylinositol arabinosyltransferase EmbC, ... 著者 Zhang, L, Zhao, Y, Gao, Y, Wang, Q, Li, J, Besra, G.S, Rao, Z. 登録日 2020-04-10 公開日 2020-04-29 最終更新日 2020-07-01 実験手法 ELECTRON MICROSCOPY (2.81 Å) 主引用文献 Structures of cell wall arabinosyltransferases with the anti-tuberculosis drug ethambutol. Science, 368, 2020
2MCN	Distinct ubiquitin binding modes exhibited by SH3 domains: molecular determinants and functional implications 分子名称: CD2-associated protein, Ubiquitin 著者 Ortega-Roldan, J, Salmon, L, Azuaga, A, Blackledge, M, Van Nuland, N. 登録日 2013-08-22 公開日 2014-02-05 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Distinct ubiquitin binding modes exhibited by SH3 domains: molecular determinants and functional implications. Plos One, 8, 2013
2M68	NMR solution structure ensemble of 3-4D mutant domain 11 IGF2R in complex with IGF2 (domain 11 structure only) 分子名称: Insulin-like growth factor 2 receptor variant 著者 Strickland, M, Williams, C, Richards, E, Minnall, L, Crump, M.P, Frago, S, Hughes, J, Garner, L, Hoppe, H, Rezgui, D, Zaccheo, O.J, Prince, S.N, Hassan, A.B, Whittaker, S. 登録日 2013-03-27 公開日 2014-10-15 最終更新日 2023-06-14 実験手法 SOLUTION NMR 主引用文献 Functional evolution of IGF2:IGF2R domain 11 binding generates novel structural interactions and a specific IGF2 antagonist. Proc.Natl.Acad.Sci.USA, 113, 2016
5FRR	Structure of the Pds5-Scc1 complex and implications for cohesin function 分子名称: SISTER CHROMATID COHESION PROTEIN PDS5 著者 Muir, K.W, Kschonsak, M, Li, Y, Metz, J, Haering, C.H, Panne, D. 登録日 2015-12-22 公開日 2016-03-02 最終更新日 2024-06-19 実験手法 X-RAY DIFFRACTION (5.8 Å) 主引用文献 Structure of the Pds5-Scc1 Complex and Implications for Cohesin Function Cell Rep., 14, 2016
4EGF	Crystal structure of a L-xylulose reductase from Mycobacterium smegmatis 分子名称: L-xylulose reductase 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID), Arakaki, T.L, Staker, B.L, Fairman, J.W. 登録日 2012-03-30 公開日 2012-05-02 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Increasing the structural coverage of tuberculosis drug targets. Tuberculosis (Edinb), 95, 2015
3NR1	A metazoan ortholog of SpoT hydrolyzes ppGpp and plays a role in starvation responses 分子名称: HD domain-containing protein 3, MANGANESE (II) ION 著者 Sun, D.W, Kim, H.Y, Kim, K.J, Jeon, Y.H, Chung, J. 登録日 2010-06-30 公開日 2010-09-08 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 A metazoan ortholog of SpoT hydrolyzes ppGpp and functions in starvation responses Nat.Struct.Mol.Biol., 17, 2010
3F38	Apoferritin: complex with 2,6-dimethylphenol 分子名称: 2,6-dimethylphenol, CADMIUM ION, Ferritin light chain, ... 著者 Vedula, L.S, Economou, N.J, Rossi, M.J, Eckenhoff, R.G, Loll, P.J. 登録日 2008-10-30 公開日 2009-07-14 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 A unitary anesthetic binding site at high resolution. J.Biol.Chem., 284, 2009
7BVG	Cryo-EM structure of Mycobacterium smegmatis arabinosyltransferase EmbA-EmbB-AcpM2 in complex with di-arabinose. 分子名称: 4'-PHOSPHOPANTETHEINE, CALCIUM ION, CARDIOLIPIN, ... 著者 Zhang, L, Zhao, Y, Gao, Y, Wang, Q, Li, J, Besra, G.S, Rao, Z. 登録日 2020-04-10 公開日 2020-04-29 最終更新日 2024-03-27 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Structures of cell wall arabinosyltransferases with the anti-tuberculosis drug ethambutol. Science, 368, 2020
5G0U	InhA in complex with a DNA encoded library hit 分子名称: 5-[(4-fluoranyl-3-phenoxy-phenyl)methylamino]-~{N}-methyl-6-[(1-pyridin-2-ylpiperidin-4-yl)amino]pyridine-3-carboxamide, ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE [NADH], NICOTINAMIDE-ADENINE-DINUCLEOTIDE 著者 Read, J.A, Breed, J. 登録日 2016-03-22 公開日 2016-11-30 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.73 Å) 主引用文献 Discovery of Cofactor-Specific, Bactericidal Mycobacterium Tuberculosis Inha Inhibitors Using DNA-Encoded Library Technology Proc.Natl.Acad.Sci.USA, 113, 2016
5YC0	Crystal structure of LP-46/N44 分子名称: Envelope glycoprotein, LP-46 著者 Zhang, X, Wang, X, He, Y. 登録日 2017-09-05 公開日 2018-02-14 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Exceptional potency and structural basis of a T1249-derived lipopeptide fusion inhibitor against HIV-1, HIV-2, and simian immunodeficiency virus J. Biol. Chem., 293, 2018
4EYE	Crystal structure of a probable oxidoreductase from Mycobacterium abscessus solved by iodide ion SAD 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, IODIDE ION, Probable oxidoreductase 著者 Edwards, T.E, Abendroth, J, Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2012-05-01 公開日 2012-05-09 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Increasing the structural coverage of tuberculosis drug targets. Tuberculosis (Edinb), 95, 2015
4XYA	Crystal Structure of the first bromodomain of human BRD4 in complex with a 2-amine-9H-purine ligand 分子名称: 1,2-ETHANEDIOL, 6-(5-bromo-1-benzofuran-7-yl)-9H-purin-2-amine, Bromodomain-containing protein 4 著者 Picaud, S, von Delft, F, Edwards, A.M, Arrowsmith, C.H, Bountra, C, Filippakopoulos, P, Structural Genomics Consortium (SGC) 登録日 2015-02-02 公開日 2015-03-11 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 9H-Purine Scaffold Reveals Induced-Fit Pocket Plasticity of the BRD9 Bromodomain. J.Med.Chem., 58, 2015
7C0Q	a Legionella pneumophila effector Lpg2505 分子名称: GLYCEROL, effector Lpg2505 著者 Chen, T.T, Han, A.D, Luo, Z.Q, McCloskey, A, Perri, K. 登録日 2020-05-01 公開日 2021-02-24 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 The metaeffector MesI regulates the activity of the Legionella effector SidI through direct protein-protein interactions. Microbes Infect., 23, 2021
4ED4	Crystal structure of IspE (4-diphosphocytidyl-2-C-methyl-D-erythritol kinase) from Mycobacterium abcessus, bound to ATP 分子名称: 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, ADENOSINE-5'-TRIPHOSPHATE 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2012-03-26 公開日 2012-04-04 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Increasing the structural coverage of tuberculosis drug targets. Tuberculosis (Edinb), 95, 2015
4XY8	Crystal Structure of the bromodomain of BRD9 in complex with a 2-amine-9H-purine ligand 分子名称: 6-(5-bromo-2-methoxyphenyl)-9H-purin-2-amine, BROMIDE ION, Bromodomain-containing protein 9 著者 Picaud, S, von Delft, F, Edwards, A.M, Arrowsmith, C.H, Bountra, C, Filippakopoulos, P, Structural Genomics Consortium (SGC) 登録日 2015-02-02 公開日 2015-03-11 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 9H-Purine Scaffold Reveals Induced-Fit Pocket Plasticity of the BRD9 Bromodomain. J.Med.Chem., 58, 2015
2N2N	Tom1 negatively modulates binding of Tollip to phosphatidylinositol 3-phosphate via a coupled folding and binding mechanism 分子名称: Target of Myb protein 1 著者 Xiao, S, Armstrong, G, Capelluto, D. 登録日 2015-05-11 公開日 2015-09-16 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Tom1 Modulates Binding of Tollip to Phosphatidylinositol 3-Phosphate via a Coupled Folding and Binding Mechanism. Structure, 23, 2015
4DOW	Structure of mouse ORC1 BAH domain bound to H4K20me2 分子名称: Histone H4, Origin recognition complex subunit 1 著者 Song, J, Patel, D.J. 登録日 2012-02-10 公開日 2012-03-07 最終更新日 2012-04-11 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 The BAH domain of ORC1 links H4K20me2 to DNA replication licensing and Meier-Gorlin syndrome. Nature, 484, 2012
3F32	Horse spleen apoferritin 分子名称: CADMIUM ION, Ferritin light chain, SULFATE ION 著者 Vedula, L.S, Economou, N.J, Rossi, M.J, Eckenhoff, R.G, Loll, P.J. 登録日 2008-10-30 公開日 2009-07-14 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 A unitary anesthetic binding site at high resolution. J.Biol.Chem., 284, 2009
3ORX	PDK1 mutant bound to allosteric disulfide fragment inhibitor 1F8 分子名称: 2-methyl-N-(2-sulfanylethyl)-1-benzofuran-3-carboxamide, 3-phosphoinositide-dependent protein kinase 1, CHLORIDE ION 著者 Sadowsky, J.D, Wells, J.A. 登録日 2010-09-08 公開日 2011-03-23 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.2044 Å) 主引用文献 Turning a protein kinase on or off from a single allosteric site via disulfide trapping. Proc.Natl.Acad.Sci.USA, 108, 2011
7BPK	Zika virus envelope protein mutant bound to mAb 分子名称: Envelope protein, IG c307_light_IGLV1-51_IGLJ2, Z3L1 Heavy chain 著者 Dai, L, Qi, J, Gao, G.F. 登録日 2020-03-23 公開日 2021-03-24 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Protective Zika vaccines engineered to eliminate enhancement of dengue infection via immunodominance switch. Nat.Immunol., 22, 2021

<388389390391392393394395396397398399400401402403>