3NWC
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9G7H
| Human Sirt6 in complex with ADP-ribose and the inhibitor 2-Pr | 分子名称: | 2,4-bis(oxidanylidene)-1-[2-oxidanylidene-2-[[(2S)-3-oxidanylidene-3-(propylamino)-2-[3-(3-pyridin-3-yl-1,2,4-oxadiazol-5-yl)propanoylamino]propyl]amino]ethyl]pyrimidine-5-carboxamide, NAD-dependent protein deacetylase sirtuin-6, SULFATE ION, ... | 著者 | You, W, Steegborn, C. | 登録日 | 2024-07-21 | 公開日 | 2024-08-14 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Elucidating the Unconventional Binding Mode of a DNA-Encoded Library Hit Provides a Blueprint for Sirtuin 6 Inhibitor Development. Chemmedchem, 2024
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5LW0
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5MWO
| Structure of Mycobacterium Tuberculosis Transcriptional Regulatory Repressor Protein (EthR) in complex with fragment 7E8. | 分子名称: | (5-methyl-1-benzothiophen-2-yl)methanol, 1,2-ETHANEDIOL, HTH-type transcriptional regulator EthR | 著者 | Mendes, V, Chan, D.S.-H, Thomas, S.E, McConnell, B, Matak-Vinkovic, D, Coyne, A.G, Abell, C, Blundell, T.L. | 登録日 | 2017-01-18 | 公開日 | 2017-05-31 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.962 Å) | 主引用文献 | Fragment Screening against the EthR-DNA Interaction by Native Mass Spectrometry. Angew. Chem. Int. Ed. Engl., 56, 2017
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5MXK
| Structure of Mycobacterium Tuberculosis Transcriptional Regulatory Repressor Protein (EthR) in complex with fragment 7G9. | 分子名称: | 1,2-ETHANEDIOL, HTH-type transcriptional regulator EthR, ~{N}-(5-oxidanylidene-7,8-dihydro-6~{H}-naphthalen-2-yl)ethanamide | 著者 | Mendes, V, Chan, D.S.-H, Thomas, S.E, McConnell, B, Matak-Vinkovic, D, Coyne, A.G, Abell, C, Blundell, T.L. | 登録日 | 2017-01-23 | 公開日 | 2017-05-31 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.932 Å) | 主引用文献 | Fragment Screening against the EthR-DNA Interaction by Native Mass Spectrometry. Angew. Chem. Int. Ed. Engl., 56, 2017
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6OIT
| CryoEM structure of Arabidopsis DDR' complex (DRD1 peptide-DMS3-RDM1) | 分子名称: | Protein CHROMATIN REMODELING 35, Protein DEFECTIVE IN MERISTEM SILENCING 3, Protein RDM1 | 著者 | Wongpalee, S.P, Liu, S, Zhou, Z.H, Jacobsen, S.E. | 登録日 | 2019-04-09 | 公開日 | 2019-07-24 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | CryoEM structures of Arabidopsis DDR complexes involved in RNA-directed DNA methylation. Nat Commun, 10, 2019
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4MTE
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4MTD
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6OIS
| CryoEM structure of Arabidopsis DR complex (DMS3-RDM1) | 分子名称: | Protein DEFECTIVE IN MERISTEM SILENCING 3, Protein RDM1 | 著者 | Wongpalee, S.P, Liu, S, Zhou, Z.H, Jacobsen, S.E. | 登録日 | 2019-04-09 | 公開日 | 2019-07-24 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | CryoEM structures of Arabidopsis DDR complexes involved in RNA-directed DNA methylation. Nat Commun, 10, 2019
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6P7E
| Structure of T7 DNA Polymerase Bound to a Primer/Template DNA and a Peptide that Mimics the C-terminal Tail of the Primase-Helicase | 分子名称: | ASP-THR-ASP-PHE peptide, DNA (25-MER), DNA (5'-D(P*GP*GP*CP*AP*GP*GP*TP*GP*GP*TP*CP*TP*TP*GP*CP*CP*GP*GP*TP*GP*A)-3'), ... | 著者 | Foster, B.M, Rosenberg, D, Salvo, H, Stephens, K.L, Bintz, B.J, Hammel, M, Ellenberger, T, Gainey, M.D, Wallen, J.R. | 登録日 | 2019-06-05 | 公開日 | 2020-03-04 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (3.001 Å) | 主引用文献 | Combined Solution and Crystal Methods Reveal the Electrostatic Tethers That Provide a Flexible Platform for Replication Activities in the Bacteriophage T7 Replisome. Biochemistry, 58, 2019
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3MZH
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8P62
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3T7K
| Complex structure of Rtt107p and phosphorylated histone H2A | 分子名称: | Histone H2A.1, Regulator of Ty1 transposition protein 107 | 著者 | Li, X, Li, F, Wu, J, Shi, Y. | 登録日 | 2011-07-30 | 公開日 | 2012-02-15 | 最終更新日 | 2017-11-08 | 実験手法 | X-RAY DIFFRACTION (2.028 Å) | 主引用文献 | Structure of C-terminal Tandem BRCT Repeats of Rtt107 Protein Reveals Critical Role in Interaction with Phosphorylated Histone H2A during DNA Damage Repair J.Biol.Chem., 287, 2012
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3CG7
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1OUZ
| Crystal structure of a mutant IHF (BetaE44A) complexed with a variant H' Site (T44A) | 分子名称: | 5'-D(*GP*CP*TP*TP*AP*TP*CP*AP*AP*TP*TP*TP*GP*TP*AP*GP*CP*AP*CP*C)-3', 5'-D(*GP*GP*CP*CP*AP*AP*AP*AP*AP*AP*GP*CP*AP*TP*T)-3', Integration Host Factor Alpha-subunit, ... | 著者 | Lynch, T.W, Read, E.K, Mattis, A.N, Gardner, J.F, Rice, P.A. | 登録日 | 2003-03-25 | 公開日 | 2003-07-15 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2.41 Å) | 主引用文献 | Integration Host Factor: putting a twist on protein-DNA recognition J.Mol.Biol., 330, 2003
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1OWF
| Crystal structure of a mutant IHF (BetaE44A) complexed with the native H' Site | 分子名称: | 5'-D(*GP*CP*TP*TP*AP*TP*CP*AP*AP*TP*TP*TP*GP*TP*TP*GP*CP*AP*CP*C)-3', 5'-D(*GP*GP*CP*CP*AP*AP*AP*AP*AP*AP*GP*CP*AP*TP*T)-3', Integration Host Factor Alpha-subunit, ... | 著者 | Lynch, T.W, Read, E.K, Mattis, A.N, Gardner, J.F, Rice, P.A. | 登録日 | 2003-03-28 | 公開日 | 2003-07-15 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Integration Host Factor: putting a twist on protein-DNA recognition J.Mol.Biol., 330, 2003
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1OWG
| Crystal structure of WT IHF complexed with an altered H' site (T44A) | 分子名称: | 5'-D(*GP*CP*TP*TP*AP*TP*CP*AP*AP*TP*TP*TP*GP*TP*AP*GP*CP*AP*CP*C)-3', 5'-D(*GP*GP*CP*CP*AP*AP*AP*AP*AP*AP*GP*CP*AP*TP*T)-3', Integration Host Factor Alpha-subunit, ... | 著者 | Lynch, T.W, Read, E.K, Mattis, A.N, Gardner, J.F, Rice, P.A. | 登録日 | 2003-03-28 | 公開日 | 2003-07-15 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Integration Host Factor: putting a twist on protein-DNA recognition J.Mol.Biol., 330, 2003
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1GU4
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1GU5
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1GTW
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8U61
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4X18
| [Ru(TAP)2(dppz-11-Me)]2+ bound to d(TCGGCGCCGA) | 分子名称: | (11-methyldipyrido[3,2-a:2',3'-c]phenazine-kappa~2~N~4~,N~5~)[bis(pyrazino[2,3-f]quinoxaline-kappa~2~N~1~,N~10~)]ruthenium, BARIUM ION, CHLORIDE ION, ... | 著者 | Hall, J.P, Cardin, C.J. | 登録日 | 2014-11-24 | 公開日 | 2015-05-13 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.05 Å) | 主引用文献 | The Structural Effect of Methyl Substitution on the Binding of Polypyridyl Ru-dppz Complexes to DNA Organometallics, 2015
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4X1A
| Lambda-[Ru(TAP)2(dppz-10,12-Me)]2+ bound to d(TCGGCGCCGA) | 分子名称: | (10,12-dimethyldipyrido[3,2-a:2',3'-c]phenazine-kappa~2~N~4~,N~5~)[bis(pyrazino[2,3-f]quinoxaline-kappa~2~N~1~,N~10~)]ruthenium, BARIUM ION, DNA (5'-D(*TP*CP*GP*GP*CP*GP*CP*CP*GP*A)-3') | 著者 | Hall, J.P, Cardin, C.J. | 登録日 | 2014-11-24 | 公開日 | 2015-05-13 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (0.89 Å) | 主引用文献 | The Structural Effect of Methyl Substitution on the Binding of Polypyridyl Ru-dppz Complexes to DNA Organometallics, 2015
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3MKL
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8P63
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