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5MXK

Structure of Mycobacterium Tuberculosis Transcriptional Regulatory Repressor Protein (EthR) in complex with fragment 7G9.

Summary for 5MXK
Entry DOI10.2210/pdb5mxk/pdb
DescriptorHTH-type transcriptional regulator EthR, ~{N}-(5-oxidanylidene-7,8-dihydro-6~{H}-naphthalen-2-yl)ethanamide, 1,2-ETHANEDIOL, ... (4 entities in total)
Functional Keywordsethr, repressor, tetr, mycobacterium tuberculosis, transcription
Biological sourceMycobacterium tuberculosis H37Rv
Total number of polymer chains1
Total formula weight24109.08
Authors
Mendes, V.,Chan, D.S.-H.,Thomas, S.E.,McConnell, B.,Matak-Vinkovic, D.,Coyne, A.G.,Abell, C.,Blundell, T.L. (deposition date: 2017-01-23, release date: 2017-05-31, Last modification date: 2024-01-17)
Primary citationChan, D.S.,Mendes, V.,Thomas, S.E.,McConnell, B.N.,Matak-Vinkovic, D.,Coyne, A.G.,Blundell, T.L.,Abell, C.
Fragment Screening against the EthR-DNA Interaction by Native Mass Spectrometry.
Angew. Chem. Int. Ed. Engl., 56:7488-7491, 2017
Cited by
PubMed: 28513917
DOI: 10.1002/anie.201702888
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.932 Å)
Structure validation

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