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6DMW
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Calmodulin-bound full-length rbTRPV5
分子名称: CALCIUM ION, Calmodulin-1, Transient receptor potential cation channel subfamily V member 5
著者Hughes, T.E.T, Pumroy, R.A, Moiseenkova-Bell, V.Y.
登録日2018-06-05
公開日2018-10-24
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (4.4 Å)
主引用文献Structural insights on TRPV5 gating by endogenous modulators.
Nat Commun, 9, 2018
6DMU
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BU of 6dmu by Molmil
PI(4,5)P2 bound full-length rbTRPV5
分子名称: Transient receptor potential cation channel subfamily V member 5, [(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate
著者Hughes, T.E.T, Pumroy, R.A, Moiseenkova-Bell, V.Y.
登録日2018-06-05
公開日2018-10-24
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献Structural insights on TRPV5 gating by endogenous modulators.
Nat Commun, 9, 2018
6DVY
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BU of 6dvy by Molmil
Cryo-EM structure of mouse TRPV3 in complex with 2-Aminoethoxydiphenyl borate (2-APB)
分子名称: 2-aminoethyl diphenylborinate, Transient receptor potential cation channel subfamily V member 3
著者Singh, A.K, McGoldrick, L.L, Sobolevsky, A.I.
登録日2018-06-25
公開日2018-09-05
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献Structure and gating mechanism of the transient receptor potential channel TRPV3.
Nat. Struct. Mol. Biol., 25, 2018
6DVW
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BU of 6dvw by Molmil
Cryo-EM structure of mouse TRPV3
分子名称: Transient receptor potential cation channel subfamily V member 3
著者Singh, A.K, McGoldrick, L.L, Sobolevsky, A.I.
登録日2018-06-25
公開日2018-09-05
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (4.3 Å)
主引用文献Structure and gating mechanism of the transient receptor potential channel TRPV3.
Nat. Struct. Mol. Biol., 25, 2018
6E2F
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BU of 6e2f by Molmil
Cryo-EM structure of human TRPV6 in complex with Calmodulin
分子名称: CALCIUM ION, Calmodulin-1, Transient receptor potential cation channel subfamily V member 6
著者Singh, A.K, McGoldrick, L.L, Sobolevsky, A.I.
登録日2018-07-11
公開日2018-08-22
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Mechanism of calmodulin inactivation of the calcium-selective TRP channel TRPV6.
Sci Adv, 4, 2018
6EBK
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BU of 6ebk by Molmil
The voltage-activated Kv1.2-2.1 paddle chimera channel in lipid nanodiscs
分子名称: NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Potassium voltage-gated channel subfamily A member 2,Potassium voltage-gated channel subfamily B member 2 chimera, Voltage-gated potassium channel subunit beta-2
著者Matthies, D, Bae, C, Fox, T, Bartesaghi, A, Subramaniam, S, Swartz, K.J.
登録日2018-08-06
公開日2018-08-22
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Single-particle cryo-EM structure of a voltage-activated potassium channel in lipid nanodiscs.
Elife, 7, 2018
6DVZ
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BU of 6dvz by Molmil
Cryo-EM structure of mouse TRPV3-Y564A in complex with 2-Aminoethoxydiphenyl borate (2-APB)
分子名称: 2-aminoethyl diphenylborinate, Transient receptor potential cation channel subfamily V member 3
著者Singh, A.K, McGoldrick, L.L, Sobolevsky, A.I.
登録日2018-06-25
公開日2018-09-05
最終更新日2019-12-18
実験手法ELECTRON MICROSCOPY (4.24 Å)
主引用文献Structure and gating mechanism of the transient receptor potential channel TRPV3.
Nat. Struct. Mol. Biol., 25, 2018
6EO1
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BU of 6eo1 by Molmil
The electron crystallography structure of the cAMP-bound potassium channel MloK1 (PCO-refined)
分子名称: Cyclic nucleotide-gated potassium channel mll3241, POTASSIUM ION
著者Kowal, J, Biyani, N, Chami, M, Scherer, S, Rzepiela, A, Baumgartner, P, Upadhyay, V, Nimigean, C, Stahlberg, H.
登録日2017-10-08
公開日2017-12-27
最終更新日2024-05-15
実験手法ELECTRON CRYSTALLOGRAPHY (4.5 Å)
主引用文献High-Resolution Cryoelectron Microscopy Structure of the Cyclic Nucleotide-Modulated Potassium Channel MloK1 in a Lipid Bilayer.
Structure, 26, 2018
6EBL
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The voltage-activated Kv1.2-2.1 paddle chimera channel in lipid nanodiscs, cytosolic domain
分子名称: NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Potassium voltage-gated channel subfamily A member 2,Potassium voltage-gated channel subfamily B member 2 chimera, Voltage-gated potassium channel subunit beta-2
著者Matthies, D, Bae, C, Fox, T, Bartesaghi, A, Subramaniam, S, Swartz, K.J.
登録日2018-08-06
公開日2018-08-22
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Single-particle cryo-EM structure of a voltage-activated potassium channel in lipid nanodiscs.
Elife, 7, 2018
6DMR
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BU of 6dmr by Molmil
Lipid-bound full-length rbTRPV5
分子名称: Transient receptor potential cation channel subfamily V member 5
著者Hughes, T.E.T, Pumroy, R.A, Moiseenkova-Bell, V.Y.
登録日2018-06-05
公開日2018-10-24
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Structural insights on TRPV5 gating by endogenous modulators.
Nat Commun, 9, 2018
6CJU
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BU of 6cju by Molmil
Structure of the SthK cyclic nucleotide-gated potassium channel in complex with cAMP
分子名称: (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, SthK cyclic nucleotide-gated potassium channel
著者Nimigean, C.M, Rheinberger, J.
登録日2018-02-26
公開日2018-08-01
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (3.35 Å)
主引用文献Ligand discrimination and gating in cyclic nucleotide-gated ion channels from apo and partial agonist-bound cryo-EM structures.
Elife, 7, 2018
7T6M
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BU of 7t6m by Molmil
Cryo-EM structure of TRPV5 in nanodiscs with PI(4,5)P2 at pH6 state 1
分子名称: Transient receptor potential cation channel subfamily V member 5, [(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate
著者Fluck, E.C, Yazici, A.T, Rohacs, T, Moiseenkova-Bell, V.Y.
登録日2021-12-14
公開日2022-05-04
最終更新日2024-02-28
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Structural basis of TRPV5 regulation by physiological and pathophysiological modulators.
Cell Rep, 39, 2022
7T6J
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BU of 7t6j by Molmil
Cryo-EM structure of TRPV5 at pH8 in nanodiscs
分子名称: Transient receptor potential cation channel subfamily V member 5
著者Fluck, E.C, Yazici, A.T, Rohacs, T, Moiseenkova-Bell, V.Y.
登録日2021-12-14
公開日2022-05-04
最終更新日2024-02-28
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Structural basis of TRPV5 regulation by physiological and pathophysiological modulators.
Cell Rep, 39, 2022
7T6K
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BU of 7t6k by Molmil
Cryo-EM structure of TRPV5 at pH6 in nanodiscs
分子名称: Transient receptor potential cation channel subfamily V member 5
著者Fluck, E.C, Yazici, A.T, Rohacs, T, Moiseenkova-Bell, V.Y.
登録日2021-12-14
公開日2022-05-04
最終更新日2024-02-28
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Structural basis of TRPV5 regulation by physiological and pathophysiological modulators.
Cell Rep, 39, 2022
7T6R
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BU of 7t6r by Molmil
Cryo-EM structure of TRPV5 T709D in nanodiscs in the presence of Calmodulin
分子名称: Transient receptor potential cation channel subfamily V member 5
著者Fluck, E.C, Yazici, A.T, Rohacs, T, Moiseenkova-Bell, V.Y.
登録日2021-12-14
公開日2022-05-04
最終更新日2024-02-28
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Structural basis of TRPV5 regulation by physiological and pathophysiological modulators.
Cell Rep, 39, 2022
7T6Q
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BU of 7t6q by Molmil
Cryo-EM structure of TRPV5 T709D with PI(4,5)P2 in nanodiscs
分子名称: Transient receptor potential cation channel subfamily V member 5, [(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate
著者Fluck, E.C, Yazici, A.T, Rohacs, T, Moiseenkova-Bell, V.Y.
登録日2021-12-14
公開日2022-05-04
最終更新日2024-02-28
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Structural basis of TRPV5 regulation by physiological and pathophysiological modulators.
Cell Rep, 39, 2022
7T6P
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BU of 7t6p by Molmil
Cryo-EM structure of TRPV5 T709D in nanodiscs
分子名称: Transient receptor potential cation channel subfamily V member 5
著者Fluck, E.C, Yazici, A.T, Rohacs, T, Moiseenkova-Bell, V.Y.
登録日2021-12-14
公開日2022-05-04
最終更新日2024-02-28
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Structural basis of TRPV5 regulation by physiological and pathophysiological modulators.
Cell Rep, 39, 2022
7T6L
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BU of 7t6l by Molmil
Cryo-EM structure of TRPV5 at pH5 in nanodiscs
分子名称: Transient receptor potential cation channel subfamily V member 5
著者Fluck, E.C, Yazici, A.T, Rohacs, T, Moiseenkova-Bell, V.Y.
登録日2021-12-14
公開日2022-05-04
最終更新日2024-02-28
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Structural basis of TRPV5 regulation by physiological and pathophysiological modulators.
Cell Rep, 39, 2022
7T6O
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BU of 7t6o by Molmil
Cryo-EM structure of TRPV5 in nanodiscs at pH6 state 3
分子名称: Transient receptor potential cation channel subfamily V member 5
著者Fluck, E.C, Yazici, A.T, Rohacs, T, Moiseenkova-Bell, V.Y.
登録日2021-12-14
公開日2022-05-04
最終更新日2024-02-28
実験手法ELECTRON MICROSCOPY (2.6 Å)
主引用文献Structural basis of TRPV5 regulation by physiological and pathophysiological modulators.
Cell Rep, 39, 2022
7T6N
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BU of 7t6n by Molmil
Cryo-EM structure of TRPV5 in nanodiscs at pH6 state 2
分子名称: Transient receptor potential cation channel subfamily V member 5
著者Fluck, E.C, Yazici, A.T, Rohacs, T, Moiseenkova-Bell, V.Y.
登録日2021-12-14
公開日2022-05-04
最終更新日2024-02-28
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Structural basis of TRPV5 regulation by physiological and pathophysiological modulators.
Cell Rep, 39, 2022
7TZC
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BU of 7tzc by Molmil
A drug and ATP binding site in type 1 ryanodine receptor
分子名称: (2S)-3-(octadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 4-[(7-methoxy-2,3-dihydro-1,4-benzothiazepin-4(5H)-yl)methyl]benzoic acid, ADENOSINE-5'-TRIPHOSPHATE, ...
著者Melville, Z, Dridi, H, Yuan, Q, Reiken, S, Anetta, W, Liu, Y, Clarke, O.B, Marks, A.R.
登録日2022-02-15
公開日2022-05-18
最終更新日2022-07-20
実験手法ELECTRON MICROSCOPY (2.45 Å)
主引用文献A drug and ATP binding site in type 1 ryanodine receptor.
Structure, 30, 2022
7UKG
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BU of 7ukg by Molmil
Human Kv4.2-KChIP2-DPP6 channel complex in an open state, transmembrane region
分子名称: Dipeptidyl-peptidase 6, POTASSIUM ION, Potassium voltage-gated channel subfamily D member 2
著者Zhao, H, Dai, Y, Lee, C.H.
登録日2022-04-01
公開日2022-06-29
最終更新日2024-02-14
実験手法ELECTRON MICROSCOPY (2.24 Å)
主引用文献Activation and closed-state inactivation mechanisms of the human voltage-gated K V 4 channel complexes.
Mol.Cell, 82, 2022
7UHF
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Human L-type voltage-gated calcium channel Cav1.3 in the presence of cinnarizine at 3.1 Angstrom resolution
分子名称: 1,2-Distearoyl-sn-glycerophosphoethanolamine, 1-(diphenylmethyl)-4-[(2E)-3-phenylprop-2-en-1-yl]piperazine, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Gao, S, Yao, X, Yan, N.
登録日2022-03-26
公開日2022-05-11
最終更新日2022-10-12
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Structural basis for pore blockade of human voltage-gated calcium channel Ca v 1.3 by motion sickness drug cinnarizine.
Cell Res., 32, 2022
7UHG
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Human L-type voltage-gated calcium channel Cav1.3 at 3.0 Angstrom resolution
分子名称: 1,2-Distearoyl-sn-glycerophosphoethanolamine, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Gao, S, Yao, X, Yan, N.
登録日2022-03-26
公開日2022-05-11
最終更新日2022-10-12
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Structural basis for pore blockade of human voltage-gated calcium channel Ca v 1.3 by motion sickness drug cinnarizine.
Cell Res., 32, 2022
7UGG
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Cryo-EM structure of TRPV3 in complex with the anesthetic dyclonine
分子名称: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, Dyclonine, SODIUM ION, ...
著者Neuberger, A, Nadezhdin, K.D, Sobolevsky, A.I.
登録日2022-03-24
公開日2022-06-08
最終更新日2024-02-14
実験手法ELECTRON MICROSCOPY (3.16 Å)
主引用文献Structural mechanism of TRPV3 channel inhibition by the anesthetic dyclonine.
Nat Commun, 13, 2022

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件を2024-08-07に公開中

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