PDB: 2705 件ウェブページステータス検索Chemie searchBIRD

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7AL7	The Crystal Structure of Human IL-18 in Complex With Human IL-18 Binding Protein 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Glutathione S-transferase class-mu 26 kDa isozyme,Interleukin-18, Interleukin-18-binding protein 著者 Detry, S, Andries, J, Bloch, Y, Clancy, D, Savvides, S.N. 登録日 2020-10-05 公開日 2022-04-20 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.801 Å) 主引用文献 Structural basis of human IL-18 sequestration by the decoy receptor IL-18 binding protein in inflammation and tumor immunity. J.Biol.Chem., 298, 2022
4L3Q	Crystal structure of glucokinase-activator complex 分子名称: 6-{3-[(1-methyl-1H-imidazol-2-yl)sulfanyl]phenyl}pyridin-2(1H)-one, Glucokinase, alpha-D-glucopyranose 著者 Gajiwala, K.S, Filipski, K.J. 登録日 2013-06-06 公開日 2013-07-24 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Pyrimidone-based series of glucokinase activators with alternative donor-acceptor motif. Bioorg.Med.Chem.Lett., 23, 2013
2W07	Structural determinants of polymerization reactivity of the P pilus adaptor subunit PapF 分子名称: CHAPERONE PROTEIN PAPD, MINOR PILIN SUBUNIT PAPF, SULFATE ION 著者 Verger, D, Rose, R.J, Paci, E, Costakes, G, Daviter, T, Hultgren, S, Remaut, H, Ashcroft, A.E, Radford, S.E, Waksman, G. 登録日 2008-08-12 公開日 2008-11-25 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structural Determinants of Polymerization Reactivity of the P Pilus Adaptor Subunit Papf. Structure, 16, 2008
2UY6	Crystal structure of the P pilus rod subunit PapA 分子名称: PAP FIMBRIAL MAJOR PILIN PROTEIN, PERIPLASMID CHAPERONE PAPD PROTEIN 著者 Verger, D, Bullitt, E, Hultgren, S.J, Waksman, G. 登録日 2007-04-02 公開日 2007-05-29 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Crystal Structure of the P Pilus Rod Subunit Papa. Plos Pathog., 3, 2007
4FOI	Crystal Structure of recombinant human Hexokinase type I mutant D413N with Glucose 1,6-bisphosphate 分子名称: 1,6-di-O-phosphono-alpha-D-glucopyranose, CITRIC ACID, Hexokinase-1, ... 著者 Shen, L, Honzatko, R.B. 登録日 2012-06-20 公開日 2013-07-03 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 DETERMINATION of SITE AFFINITY CONSTANTS FOR PRODUCT INHIBITION OF WILD-TYPE AND MUTANT FORMS OF RECOMBINANT HUMAN HEXOKINASE TYPE I To be Published
4FPA	Crystal Structure of recombinant human Hexokinase type I mutant D413N Glucose 6-Phosphate 分子名称: 6-O-phosphono-beta-D-glucopyranose, CITRIC ACID, Hexokinase-1, ... 著者 Shen, L, Honzatko, R.B. 登録日 2012-06-21 公開日 2013-07-03 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.48 Å) 主引用文献 DETERMINATION OF SITE AFFINITY CONSTANTS FOR PRODUCT INHIBITION of WILD-TYPE AND MUTANT FORMS OF RECOMBINANT HUMAN HEXOKINASE TYPE I To be Published
4ISF	Human glucokinase in complex with novel activator (2S)-3-cyclohexyl-2-(6-fluoro-2,4-dioxo-1,4-dihydroquinazolin-3(2H)-yl)-N-(1,3-thiazol-2-yl)propanamide 分子名称: (2S)-3-cyclohexyl-2-(6-fluoro-2,4-dioxo-1,4-dihydroquinazolin-3(2H)-yl)-N-(1,3-thiazol-2-yl)propanamide, Glucokinase, IODIDE ION, ... 著者 Hosfield, D, Skene, R.J. 登録日 2013-01-16 公開日 2013-03-20 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.09 Å) 主引用文献 Design, synthesis and SAR of novel glucokinase activators. Bioorg.Med.Chem.Lett., 23, 2013
4FPB	Crystal Structure of Recombinant Human Hexokinase Type I with 1,5-Anhydroglucitol 6-Phosphate 分子名称: 1,5-anhydro-6-O-phosphono-D-glucitol, CITRIC ACID, Hexokinase-1, ... 著者 Shen, L, Honzatko, R.B. 登録日 2012-06-21 公開日 2013-07-03 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Inhibitor Sites of Unequal Affinity Linked by Binding Synergism in Mutant Forms of Recombinant Human Hexokinase Type-I to be published
1RH5	The structure of a protein conducting channel 分子名称: Preprotein translocase secE subunit, Preprotein translocase secY subunit, SecBeta 著者 van den Berg, B, Clemons Jr, W.M, Collinson, I, Modis, Y, Hartmann, E, Harrison, S.C, Rapoport, T.A. 登録日 2003-11-13 公開日 2004-01-06 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 X-ray structure of a protein-conducting channel Nature, 427, 2004
7JTH	Cryo-EM structure of unliganded octameric prenyltransferase domain of Phomopsis amygdali fusicoccadiene synthase 分子名称: Fusicoccadiene synthase 著者 Faylo, J.L, van Eeuwen, T, Murakami, K, Christianson, D.W. 登録日 2020-08-17 公開日 2021-04-28 最終更新日 2024-05-29 実験手法 ELECTRON MICROSCOPY (4 Å) 主引用文献 Structural insight on assembly-line catalysis in terpene biosynthesis. Nat Commun, 12, 2021
1RHZ	The structure of a protein conducting channel 分子名称: Preprotein translocase secE subunit, Preprotein translocase secY subunit, SecBeta 著者 van den Berg, B, Clemons Jr, W.M, Collinson, I, Modis, Y, Hartmann, E, Harrison, S.C, Rapoport, T.A. 登録日 2003-11-15 公開日 2004-01-06 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (3.5 Å) 主引用文献 X-ray structure of a protein-conducting channel. Nature, 427, 2004
4LC9	Structural Basis for Regulation of Human Glucokinase by Glucokinase Regulatory Protein 分子名称: 6-O-phosphono-beta-D-fructofuranose, Glucokinase, Glucokinase regulatory protein, ... 著者 Beck, T, Miller, B.G. 登録日 2013-06-21 公開日 2013-09-04 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (3.4 Å) 主引用文献 Structural basis for regulation of human glucokinase by glucokinase regulatory protein. Biochemistry, 52, 2013
1RV6	Crystal Structure of PlGF in Complex with Domain 2 of VEGFR1 分子名称: 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, FLT1 protein, placenta growth factor (PlGF) 著者 Christinger, H.W, Fuh, G, de Vos, A.M, Wiesmann, C. 登録日 2003-12-12 公開日 2004-01-20 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.45 Å) 主引用文献 The crystal structure of placental growth factor in complex with domain 2 of vascular endothelial growth factor receptor-1. J.Biol.Chem., 279, 2004
4EEE	Crystal Structure of YLDV 14L IL-18 Binding Protein in Complex with Human IL-18 分子名称: 14L protein, Interleukin-18 著者 Krumm, B.E, Xiang, Y, Deng, J. 登録日 2012-03-28 公開日 2012-09-26 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.71 Å) 主引用文献 A unique bivalent binding and inhibition mechanism by the yatapoxvirus interleukin 18 binding protein. Plos Pathog., 8, 2012
5GHU	Crystal structure of YadV chaperone at 1.63 Angstrom 分子名称: ACETATE ION, CHLORIDE ION, FORMIC ACID, ... 著者 Pandey, N.K, Bhavesh, N.S. 登録日 2016-06-20 公開日 2017-06-28 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.63 Å) 主引用文献 Crystal structure of the usher chaperone YadV reveals a monomer with the proline lock in closed conformation suggestive of an intermediate state. Febs Lett., 2020
7B0W	Crystal structure of the E. coli type 1 pilus assembly inhibitor FimI bound to FimC 分子名称: 1,2-ETHANEDIOL, Chaperone protein FimC, FORMIC ACID, ... 著者 Scharer, M.A, Zigova, Z, Giese, C, Puorger, C, Ignatov, O, Capitani, G, Glockshuber, R. 登録日 2020-11-23 公開日 2021-12-08 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Comprehensive kinetic characterization of bacterial pilus rod assembly and assembly termination To Be Published
7B0X	Crystal structure of the ternary complex of the E. coli type 1 pilus proteins FimC, FimI and the N-terminal domain of FimD 分子名称: 1,2-ETHANEDIOL, Chaperone protein FimC, Fimbrin-like protein FimI, ... 著者 Scharer, M.A, Zigova, Z, Giese, C, Puorger, C, Ignatov, O, Capitani, G, Glockshuber, R. 登録日 2020-11-23 公開日 2021-12-08 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Comprehensive kinetic characterization of bacterial pilus rod assembly and assembly termination To Be Published
4IWV	Crystals structure of Human Glucokinase in complex with small molecule activator 分子名称: (2S)-2-{[1-(2-chlorophenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-yl]oxy}-N-(5-chloropyridin-2-yl)-3-(2-hydroxyethoxy)propanamide, Glucokinase isoform 3, SODIUM ION, ... 著者 Ogg, D.J, Hargreaves, D, Gerhardt, S, Flavell, L, McAlister, M. 登録日 2013-01-24 公開日 2013-04-24 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Optimising pharmacokinetics of glucokinase activators with matched triplicate design sets the discovery of AZD3651 and AZD9485 To be Published
4J3O	Crystal structure of the FimD usher traversed by the pilus tip complex assembly composed of FimC:FimF:FimG:FimH 分子名称: Chaperone protein FimC, Outer membrane usher protein FimD, Protein FimF, ... 著者 Geibel, S, Waksman, G. 登録日 2013-02-06 公開日 2013-04-10 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (3.8 Å) 主引用文献 Structural and energetic basis of folded-protein transport by the FimD usher. Nature, 496, 2013
4ISG	Human glucokinase in complex with novel activator (2S)-3-cyclohexyl-2-[4-(methylsulfonyl)-2-oxopiperazin-1-yl]-N-(1,3-thiazol-2-yl)propanamide 分子名称: (2S)-3-cyclohexyl-2-[4-(methylsulfonyl)-2-oxopiperazin-1-yl]-N-(1,3-thiazol-2-yl)propanamide, Glucokinase, IODIDE ION, ... 著者 Hosfield, D, Skene, R.J. 登録日 2013-01-16 公開日 2013-03-20 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.645 Å) 主引用文献 Design, synthesis and SAR of novel glucokinase activators. Bioorg.Med.Chem.Lett., 23, 2013
1V4T	Crystal structure of human glucokinase 分子名称: SODIUM ION, SULFATE ION, glucokinase isoform 2 著者 Kamata, K, Mitsuya, M, Nishimura, T, Eiki, J, Nagata, Y. 登録日 2003-11-19 公開日 2004-03-30 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (3.4 Å) 主引用文献 Structural basis for allosteric regulation of the monomeric allosteric enzyme human glucokinase Structure, 12, 2004
2WMP	Structure of the E. coli chaperone PapD in complex with the pilin domain of the PapGII adhesin 分子名称: CHAPERONE PROTEIN PAPD, PAPG PROTEIN 著者 Ford, B.A, Verger, D, Elam, J.S, Dodson, K.W, Pinkner, J.S, Hultgren, S.J. 登録日 2009-07-02 公開日 2010-08-25 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structure of the Papd-Papgii Pilin Complex Reveals an Open and Flexible P5 Pocket. J.Bacteriol., 194, 2012
1V4S	Crystal structure of human glucokinase 分子名称: 2-AMINO-4-FLUORO-5-[(1-METHYL-1H-IMIDAZOL-2-YL)SULFANYL]-N-(1,3-THIAZOL-2-YL)BENZAMIDE, SODIUM ION, alpha-D-glucopyranose, ... 著者 Kamata, K, Mitsuya, M, Nishimura, T, Eiki, J, Nagata, Y. 登録日 2003-11-19 公開日 2004-03-30 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structural basis for allosteric regulation of the monomeric allosteric enzyme human glucokinase Structure, 12, 2004
3O5B	Crystal structure of dimeric KlHxk1 in crystal form VII with glucose bound (open state) 分子名称: Hexokinase, SULFATE ION, beta-D-glucopyranose 著者 Kuettner, E.B, Kettner, K, Keim, A, Kriegel, T.M, Strater, N. 登録日 2010-07-28 公開日 2010-10-13 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.97 Å) 主引用文献 Crystal Structure of Hexokinase KlHxk1 of Kluyveromyces lactis: A MOLECULAR BASIS FOR UNDERSTANDING THE CONTROL OF YEAST HEXOKINASE FUNCTIONS VIA COVALENT MODIFICATION AND OLIGOMERIZATION. J.Biol.Chem., 285, 2010
1HKB	CRYSTAL STRUCTURE OF RECOMBINANT HUMAN BRAIN HEXOKINASE TYPE I COMPLEXED WITH GLUCOSE AND GLUCOSE-6-PHOSPHATE 分子名称: 6-O-phosphono-alpha-D-glucopyranose, CALCIUM ION, D-GLUCOSE 6-PHOSPHOTRANSFERASE, ... 著者 Aleshin, A.E, Zeng, C, Burenkov, G.P, Bartunik, H.D, Fromm, H.J, Honzatko, R.B. 登録日 1997-12-01 公開日 1998-06-03 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 The mechanism of regulation of hexokinase: new insights from the crystal structure of recombinant human brain hexokinase complexed with glucose and glucose-6-phosphate. Structure, 6, 1998

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