PDB: 1359 件ウェブページステータス検索Chemie searchBIRD

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2NGR	TRANSITION STATE COMPLEX FOR GTP HYDROLYSIS BY CDC42: COMPARISONS OF THE HIGH RESOLUTION STRUCTURES FOR CDC42 BOUND TO THE ACTIVE AND CATALYTICALLY COMPROMISED FORMS OF THE CDC42-GAP. 分子名称: ALUMINUM FLUORIDE, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... 著者 Nassar, N, Hoffman, G, Clardy, J, Cerione, R. 登録日 1998-07-31 公開日 1999-01-06 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structures of Cdc42 bound to the active and catalytically compromised forms of Cdc42GAP. Nat.Struct.Biol., 5, 1998
1RRP	STRUCTURE OF THE RAN-GPPNHP-RANBD1 COMPLEX 分子名称: MAGNESIUM ION, NUCLEAR PORE COMPLEX PROTEIN NUP358, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ... 著者 Vetter, I.R, Nowak, C, Nishimoto, T, Kuhlmann, J, Wittinghofer, A. 登録日 1999-01-15 公開日 1999-05-18 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.96 Å) 主引用文献 Structure of a Ran-binding domain complexed with Ran bound to a GTP analogue: implications for nuclear transport. Nature, 398, 1999
2NTY	Rop4-GDP-PRONE8 分子名称: Emb|CAB41934.1, GUANOSINE-5'-DIPHOSPHATE, Rac-like GTP-binding protein ARAC5 著者 Thomas, C, Fricke, I, Scrima, A, Berken, A, Wittinghofer, A. 登録日 2006-11-08 公開日 2007-01-23 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Structural Evidence for a Common Intermediate in Small G Protein-GEF Reactions Mol.Cell, 25, 2007
2MSD	NMR data-driven model of GTPase KRas-GNP tethered to a lipid-bilayer nanodisc 分子名称: 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Apolipoprotein A-I, GTPase KRas, ... 著者 Mazhab-Jafari, M, Stathopoulos, P, Marshall, C, Ikura, M. 登録日 2014-07-29 公開日 2015-06-03 最終更新日 2024-05-01 実験手法 SOLUTION NMR 主引用文献 Oncogenic and RASopathy-associated K-RAS mutations relieve membrane-dependent occlusion of the effector-binding site. Proc.Natl.Acad.Sci.USA, 112, 2015
2NZ8	N-terminal DHPH cassette of Trio in complex with nucleotide-free Rac1 分子名称: ras-related C3 botulinum toxin substrate 1 isoform Rac1, triple functional domain protein 著者 Chhatriwala, M.K, Betts, L, Worthylake, D.K, Sondek, J. 登録日 2006-11-22 公開日 2007-04-10 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 The DH and PH Domains of Trio Coordinately Engage Rho GTPases for their Efficient Activation J.Mol.Biol., 368, 2007
2KWI	RalB-RLIP76 (RalBP1) complex 分子名称: MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, RalA-binding protein 1, ... 著者 Fenwick, R.B, Campbell, L.J, Rajasekar, K, Prasannan, S, Nietlispach, D, Camonis, J, Owen, D, Mott, H.R. 登録日 2010-04-12 公開日 2010-09-01 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 The RalB-RLIP76 complex reveals a novel mode of ral-effector interaction Structure, 18, 2010
4LWZ	Crystal structure of Myo5b globular tail domain in complex with inactive Rab11a 分子名称: GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Ras-related protein Rab-11A, ... 著者 Pylypenko, O, Attanda, W, Gauquelin, C, Houdusse, A. 登録日 2013-07-29 公開日 2013-11-20 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.55 Å) 主引用文献 Structural basis of myosin V Rab GTPase-dependent cargo recognition. Proc.Natl.Acad.Sci.USA, 110, 2013
4M8N	Crystal Structure of PlexinC1/Rap1B Complex 分子名称: ALUMINUM FLUORIDE, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... 著者 Pascoe, H.G, Wang, Y, Brautigam, C.A, He, H, Zhang, X. 登録日 2013-08-13 公開日 2013-10-09 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (3.294 Å) 主引用文献 Structural basis for activation and non-canonical catalysis of the Rap GTPase activating protein domain of plexin. Elife, 2, 2013
4MIT	Crystal structure of E. histolytica RacC bound to the EhPAK4 PBD 分子名称: GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Rho family GTPase, ... 著者 Bosch, D.E, Siderovski, D.P. 登録日 2013-09-02 公開日 2014-09-03 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 Entamoeba histolytica RacC Selectively Engages p21-Activated Kinase Effectors. Biochemistry, 54, 2015
3BC1	Crystal Structure of the complex Rab27a-Slp2a 分子名称: MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, Ras-related protein Rab-27A, ... 著者 Chavas, L.M.G, Ihara, K, Kawasaki, M, Wakatsuki, S. 登録日 2007-11-12 公開日 2008-09-02 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Elucidation of Rab27 recruitment by its effectors: structure of Rab27a bound to Exophilin4/Slp2-a Structure, 16, 2008
4NYI	Approach for Targeting Ras with Small Molecules that Activate SOS-Mediated Nucleotide Exchange 分子名称: GTPase HRas, MAGNESIUM ION, N-{1-[(5-methyl-1H-indol-3-yl)methyl]piperidin-4-yl}-L-tryptophanamide, ... 著者 Burns, M.C, Sun, Q, Phan, J, Fesik, S.W. 登録日 2013-12-10 公開日 2014-03-12 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.9612 Å) 主引用文献 Approach for targeting Ras with small molecules that activate SOS-mediated nucleotide exchange. Proc.Natl.Acad.Sci.USA, 111, 2014
4OL0	Crystal structure of transportin-SR2, a karyopherin involved in human disease, in complex with Ran 分子名称: GTP-binding nuclear protein Ran, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... 著者 Tsirkone, V.G, Strelkov, S.V. 登録日 2014-01-23 公開日 2014-04-09 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Structure of transportin SR2, a karyopherin involved in human disease, in complex with Ran. Acta Crystallogr.,Sect.F, 70, 2014
3CH5	The crystal structure of the RanGDP-Nup153ZnF2 complex 分子名称: Fragment of Nuclear pore complex protein Nup153, GTP-binding nuclear protein Ran, GUANOSINE-5'-DIPHOSPHATE, ... 著者 Vetter, I.R, Schrader, N. 登録日 2008-03-07 公開日 2008-07-01 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 The Crystal Structure of the Ran-Nup153ZnF2 Complex: a General Ran Docking Site at the Nuclear Pore Complex Structure, 16, 2008
3BJI	Structural Basis of Promiscuous Guanine Nucleotide Exchange by the T-Cell Essential Vav1 分子名称: Proto-oncogene vav, Ras-related C3 botulinum toxin substrate 1 precursor, ZINC ION 著者 Chrencik, J.E, Brooun, A, Kuhn, P, Accelerated Technologies Center for Gene to 3D Structure (ATCG3D) 登録日 2007-12-04 公開日 2008-07-15 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Structural basis of guanine nucleotide exchange mediated by the T-cell essential Vav1. J.Mol.Biol., 380, 2008
3CPJ	Crystal structure of Ypt31 in complex with yeast Rab-GDI 分子名称: CHLORIDE ION, GTP-binding protein YPT31/YPT8, GUANOSINE-5'-DIPHOSPHATE, ... 著者 Kravchenko, S, Ignatev, A, Goody, R.S, Rak, A, Pylypenko, O. 登録日 2008-03-31 公開日 2008-05-06 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 A structural model of the GDP dissociation inhibitor rab membrane extraction mechanism. J.Biol.Chem., 283, 2008
3CUE	Crystal structure of a TRAPP subassembly activating the Rab Ypt1p 分子名称: GTP-binding protein YPT1, PALMITIC ACID, Transport protein particle 18 kDa subunit, ... 著者 Cai, Y, Reinisch, K.M. 登録日 2008-04-16 公開日 2008-07-08 最終更新日 2012-03-21 実験手法 X-RAY DIFFRACTION (3.7 Å) 主引用文献 The structural basis for activation of the Rab Ypt1p by the TRAPP membrane-tethering complexes. Cell(Cambridge,Mass.), 133, 2008
3CWZ	Structure of RAB6(GTP)-R6IP1 complex 分子名称: GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Rab6-interacting protein 1, ... 著者 Recacha, R, Houdusse, A, Goud, B, Khan, A.R. 登録日 2008-04-23 公開日 2008-11-18 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Structural basis for recruitment of Rab6-interacting protein 1 to Golgi via a RUN domain. Structure, 17, 2009
3BBP	Rab6-GTP:GCC185 Rab binding domain complex 分子名称: GRIP and coiled-coil domain-containing protein 2, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... 著者 Schweizer Burguete, A, Fenn, T.D, Brunger, A.T, Pfeffer, S.R. 登録日 2007-11-09 公開日 2008-02-05 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Rab and Arl GTPase family members cooperate in the localization of the golgin GCC185. Cell(Cambridge,Mass.), 132, 2008
3CPH	Crystal structure of Sec4 in complex with Rab-GDI 分子名称: GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Rab GDP-dissociation inhibitor, ... 著者 Kravchenko, S, Ignatev, A, Goody, R.S, Rak, A, Pylypenko, O. 登録日 2008-03-31 公開日 2008-05-06 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 A structural model of the GDP dissociation inhibitor rab membrane extraction mechanism. J.Biol.Chem., 283, 2008
3DDC	Crystal Structure of NORE1A in Complex with RAS 分子名称: GTPase HRas, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ... 著者 Stieglitz, B, Bee, C, Schwarz, D, Yildiz, O, Moshnikova, A, Khokhlatchev, A, Herrmann, C. 登録日 2008-06-05 公開日 2008-07-15 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Novel type of Ras effector interaction established between tumour suppressor NORE1A and Ras switch II Embo J., 27, 2008
4NYM	Approach for Targeting Ras with Small Molecules that Activate SOS-Mediated Nucleotide Exchange 分子名称: GTPase HRas, MAGNESIUM ION, N-[1-(1H-indol-3-ylmethyl)piperidin-4-yl]-L-tryptophanamide, ... 著者 Burns, M.C, Sun, Q, Phan, J, Fesik, S.W. 登録日 2013-12-10 公開日 2014-03-12 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (3.5529 Å) 主引用文献 Approach for targeting Ras with small molecules that activate SOS-mediated nucleotide exchange. Proc.Natl.Acad.Sci.USA, 111, 2014
3B13	Crystal structure of the DHR-2 domain of DOCK2 in complex with Rac1 (T17N mutant) 分子名称: Dedicator of cytokinesis protein 2, Ras-related C3 botulinum toxin substrate 1 著者 Hanawa-Suetsugu, K, Kukimoto-Niino, M, Mishima-Tsumagari, C, Terada, T, Shirouzu, M, Fukui, Y, Yokoyama, S. 登録日 2011-06-24 公開日 2012-03-14 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (3.006 Å) 主引用文献 Structural basis for mutual relief of the Rac guanine nucleotide exchange factor DOCK2 and its partner ELMO1 from their autoinhibited forms. Proc.Natl.Acad.Sci.USA, 109, 2012
3CLV	Crystal Structure of Rab5a from plasmodium falciparum, PFB0500c 分子名称: CHLORIDE ION, GUANOSINE-5'-DIPHOSPHATE, Rab5 protein, ... 著者 Chattopadhyay, D, Wernimont, A.K, Langsley, G, Lew, J, Kozieradzki, I, Cossar, D, Schapira, M, Bochkarev, A, Arrowsmith, C.H, Bountra, C, Weigelt, J, Edwards, A.M, Hui, R, Sukumar, D, Structural Genomics Consortium (SGC) 登録日 2008-03-20 公開日 2008-07-15 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.89 Å) 主引用文献 Crystal Structure of Rab5a from plasmodium falciparum, PFB0500c To be Published
3BRW	Structure of the Rap-RapGAP complex 分子名称: BERYLLIUM TRIFLUORIDE ION, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... 著者 Scrima, A, Thomas, C, Deaconescu, D, Wittinghofer, A. 登録日 2007-12-21 公開日 2008-03-11 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (3.4 Å) 主引用文献 The Rap-RapGAP complex: GTP hydrolysis without catalytic glutamine and arginine residues Embo J., 27, 2008
3EA5	Kap95p Binding Induces the Switch Loops of RanGDP to adopt the GTP-bound Conformation: Implications for Nuclear Import Complex Assembly Dynamics 分子名称: GTP-binding nuclear protein Ran, GUANOSINE-5'-DIPHOSPHATE, Importin subunit beta-1, ... 著者 Forwood, J.K, Lonhienne, J.K, Guncar, G, Stewart, M, Marfori, M, Kobe, B. 登録日 2008-08-24 公開日 2008-10-21 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Kap95p binding induces the switch loops of RanGDP to adopt the GTP-bound conformation: implications for nuclear import complex assembly dynamics. J.Mol.Biol., 383, 2008

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