PDB: 22592 件ウェブページステータス検索Chemie searchBIRD

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4TRI	X-ray crystal structure of CYP142A2 from Mycobacterium smegmatis, complexed with cholesterol sulfate. 分子名称: CHOLEST-5-EN-3-YL HYDROGEN SULFATE, GLYCEROL, P450 heme-thiolate protein, ... 著者 Madrona, Y, Ortiz de Montellano, P. 登録日 2014-06-17 公開日 2014-09-17 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Cholesterol ester oxidation by mycobacterial cytochrome p450. J.Biol.Chem., 289, 2014
4Y9I	Structure of F420-H2 Dependent Reductase (FDR-A) msmeg_2027 分子名称: Mycobacterium tuberculosis paralogous family 11, PHOSPHATE ION 著者 Ahmed, F.H, Carr, P.D, Jackson, C.J. 登録日 2015-02-17 公開日 2015-10-21 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.498 Å) 主引用文献 Sequence-Structure-Function Classification of a Catalytically Diverse Oxidoreductase Superfamily in Mycobacteria. J.Mol.Biol., 427, 2015
4UAX	X-ray crystal structure of ligand free CYP142A2 from Mycobacterium smegmatis 分子名称: P450 heme-thiolate protein, PROTOPORPHYRIN IX CONTAINING FE 著者 Madrona, Y. 登録日 2014-08-11 公開日 2014-09-17 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.78 Å) 主引用文献 Cholesterol ester oxidation by mycobacterial cytochrome p450. J.Biol.Chem., 289, 2014
4QVB	Mycobacterium tuberculosis protein Rv1155 in complex with co-enzyme F420 分子名称: 1,2-ETHANEDIOL, 1,3-PROPANDIOL, COENZYME F420, ... 著者 Mashalidis, E.H, Gittis, A.G, Tomczak, A, Abell, C, Barry III, C.E, Garboczi, D.N. 登録日 2014-07-14 公開日 2015-02-25 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Molecular insights into the binding of coenzyme F420 to the conserved protein Rv1155 from Mycobacterium tuberculosis. Protein Sci., 24, 2015
5EBD	Crystal structure of EccB1 of Mycobacterium tuberculosis in spacegroup P21 (state IV) 分子名称: CALCIUM ION, CHLORIDE ION, ESX-1 secretion system protein eccB1 著者 Zhang, X.L, Qi, C, Xie, X.Q, Li, D.F, Bi, L.J. 登録日 2015-10-19 公開日 2016-02-17 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Crystallographic observation of the movement of the membrane-distal domain of the T7SS core component EccB1 from Mycobacterium tuberculosis. Acta Crystallogr.,Sect.F, 72, 2016
3QPL	G106W mutant of EthR from Mycobacterium tuberculosis 分子名称: HTH-type transcriptional regulator EthR 著者 Carette, X, Willery, E, Hoos, S, Lecat-Guillet, N, Frenois, F, Dirie, B, Villeret, V, England, P, Deprez, B, Locht, C, Willand, N, Baulard, A. 登録日 2011-02-14 公開日 2011-12-28 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Structural activation of the transcriptional repressor EthR from Mycobacterium tuberculosis by single amino acid change mimicking natural and synthetic ligands. Nucleic Acids Res., 40, 2012
4WYE	Crystal structure of 7,8-diaminopelargonic acid synthase (BioA) from Mycobacterium tuberculosis complexed with a DSF fragment hit 分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ACETONE, Adenosylmethionine-8-amino-7-oxononanoate aminotransferase, ... 著者 Dai, R, Finzel, B.C. 登録日 2014-11-17 公開日 2015-07-08 最終更新日 2015-07-22 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Fragment-Based Exploration of Binding Site Flexibility in Mycobacterium tuberculosis BioA. J.Med.Chem., 58, 2015
4XJO	Crystal structure of 7,8-diaminopelargonic acid synthase (BioA) from Mycobacterium tuberculosis, complexed with an inhibitor optimized from HTS lead 分子名称: 1,2-ETHANEDIOL, 5-[4-(3-chlorobenzoyl)piperazin-1-yl]-1H-inden-1-one, Adenosylmethionine-8-amino-7-oxononanoate aminotransferase, ... 著者 Finzel, B.C, Dai, R. 登録日 2015-01-08 公開日 2016-01-20 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Structure-Based Optimization of Pyridoxal 5'-Phosphate-Dependent Transaminase Enzyme (BioA) Inhibitors that Target Biotin Biosynthesis in Mycobacterium tuberculosis. J. Med. Chem., 60, 2017
4XOO	FMN complex of coenzyme F420:L-glutamate ligase (FbiB) from Mycobacterium tuberculosis (C-terminal domain) 分子名称: Coenzyme F420:L-glutamate ligase, FLAVIN MONONUCLEOTIDE 著者 Rehan, A.M, Bashiri, G, Baker, H.M, Baker, E.N, Squire, C.J. 登録日 2015-01-16 公開日 2016-02-17 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Elongation of the Poly-gamma-glutamate Tail of F420 Requires Both Domains of the F420: gamma-Glutamyl Ligase (FbiB) of Mycobacterium tuberculosis. J.Biol.Chem., 291, 2016
4XJP	Crystal structure of 7,8-diaminopelargonic acid synthase (BioA) from Mycobacterium tuberculosis, complexed with an inhibitor optimized from HTS lead 分子名称: 1,2-ETHANEDIOL, 1-{4-[4-(1,3-benzodioxol-5-ylcarbonyl)piperazin-1-yl]phenyl}ethanone, Adenosylmethionine-8-amino-7-oxononanoate aminotransferase, ... 著者 Finzel, B.C, Dai, R. 登録日 2015-01-08 公開日 2016-01-20 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Structure-Based Optimization of Pyridoxal 5'-Phosphate-Dependent Transaminase Enzyme (BioA) Inhibitors that Target Biotin Biosynthesis in Mycobacterium tuberculosis. J. Med. Chem., 60, 2017
4XOQ	F420 complex of coenzyme F420:L-glutamate ligase (FbiB) from Mycobacterium tuberculosis (C-terminal domain) 分子名称: COENZYME F420, Coenzyme F420:L-glutamate ligase, SULFATE ION 著者 Rehan, A.M, Bashiri, G, Baker, H.M, Baker, E.N, Squire, C.J. 登録日 2015-01-16 公開日 2016-02-17 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Elongation of the Poly-gamma-glutamate Tail of F420 Requires Both Domains of the F420: gamma-Glutamyl Ligase (FbiB) of Mycobacterium tuberculosis. J.Biol.Chem., 291, 2016
3NOF	Mycobacterium tuberculosis thioredoxin C C40S mutant 分子名称: THIOCYANATE ION, Thioredoxin TrxC 著者 Hall, G, Emsley, J. 登録日 2010-06-25 公開日 2010-11-10 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Structure of Mycobacterium tuberculosis thioredoxin in complex with quinol inhibitor PMX464 Protein Sci., 20, 2011
4XOM	Coenzyme F420:L-glutamate ligase (FbiB) from Mycobacterium tuberculosis (C-terminal domain). 分子名称: Coenzyme F420:L-glutamate ligase, SULFATE ION 著者 Rehan, A.M, Bashiri, G, Baker, H.M, Baker, E.N, Squire, C.J. 登録日 2015-01-16 公開日 2016-02-17 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Elongation of the Poly-gamma-glutamate Tail of F420 Requires Both Domains of the F420: gamma-Glutamyl Ligase (FbiB) of Mycobacterium tuberculosis. J.Biol.Chem., 291, 2016
4XT4	Crystal structure of Rv2671 from Mycobacteirum tuberculosis in complex with dihydropteridine ring of dihydropteroic acid 分子名称: 2-amino-6-methyl-7,8-dihydropteridin-4(3H)-one, GLYCEROL, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... 著者 Sacchettini, J.C, Cheng, Y.S, TB Structural Genomics Consortium (TBSGC) 登録日 2015-01-22 公開日 2016-02-24 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.891 Å) 主引用文献 Structural Insights into Mycobacterium tuberculosis Rv2671 Protein as a Dihydrofolate Reductase Functional Analogue Contributing to para-Aminosalicylic Acid Resistance. Biochemistry, 55, 2016
7Y41	Mycobacterium smegmatis 50S ribosomal subunit from Log Phase of growth 分子名称: 23S ribosomal RNA, 50S ribosomal protein L10, 50S ribosomal protein L11, ... 著者 Sengupta, J, Baid, P. 登録日 2022-06-13 公開日 2023-05-03 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (4.1 Å) 主引用文献 Cryo-EM captures a unique conformational rearrangement in 23S rRNA helices of the Mycobacterium 50S subunit. Int.J.Biol.Macromol., 253, 2023
4WYF	Crystal structure of 7,8-diaminopelargonic acid synthase (BioA) from Mycobacterium tuberculosis, complexed with a DSF fragment hit 分子名称: Adenosylmethionine-8-amino-7-oxononanoate aminotransferase, N-(1-oxo-1H-inden-5-yl)acetamide, PYRIDOXAL-5'-PHOSPHATE 著者 Barry, C.F, Dai, R. 登録日 2014-11-17 公開日 2015-07-08 最終更新日 2015-07-22 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Fragment-Based Exploration of Binding Site Flexibility in Mycobacterium tuberculosis BioA. J.Med.Chem., 58, 2015
4WYG	Crystal structure of 7,8-diaminopelargonic acid synthase (BioA) from Mycobacterium tuberculosis complexed with a fragment hit 分子名称: 1,2-ETHANEDIOL, 1-{4-[(4-chloro-1H-pyrazol-1-yl)methyl]phenyl}methanamine, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... 著者 Dai, R, Finzel, B.C. 登録日 2014-11-17 公開日 2015-07-08 最終更新日 2015-07-22 実験手法 X-RAY DIFFRACTION (1.62 Å) 主引用文献 Fragment-Based Exploration of Binding Site Flexibility in Mycobacterium tuberculosis BioA. J.Med.Chem., 58, 2015
7XAM	Mycobacterium smegmatis 50S ribosomal subunit from Stationary phase of growth 分子名称: 23S rRNA, 50S ribosomal protein L10, 50S ribosomal protein L11, ... 著者 Sengupta, J, Baid, P. 登録日 2022-03-18 公開日 2023-05-03 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 Cryo-EM captures a unique conformational rearrangement in 23S rRNA helices of the Mycobacterium 50S subunit. Int.J.Biol.Macromol., 253, 2023
4R9Z	Mycobacterium avium subs paratuberculosis tesB protein MAP1729c 分子名称: Uncharacterized protein 著者 Swarbrick, C.M.D, Forwood, J.K. 登録日 2014-09-08 公開日 2014-10-08 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Mycobacterium avium subs paratuberculosis tesB protein MAP1729c TO BE PUBLISHED
4WYC	Crystal structure of 7,8-diaminopelargonic acid synthase (BioA) from Mycobacterium tuberculosis, complexed with a thiazole benzamide inhibitor 分子名称: 1,2-ETHANEDIOL, 4-(1H-imidazol-1-yl)benzamide, Adenosylmethionine-8-amino-7-oxononanoate aminotransferase, ... 著者 Finzel, B.C, Dai, R, Geders, T.W. 登録日 2014-11-17 公開日 2015-07-08 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Fragment-Based Exploration of Binding Site Flexibility in Mycobacterium tuberculosis BioA. J.Med.Chem., 58, 2015
4WZF	Crystal structural basis for Rv0315, an immunostimulatory antigen and pseudo beta-1, 3-glucanase of Mycobacterium tuberculosis 分子名称: 1,2-ETHANEDIOL, 1,3-beta-glucanase, CALCIUM ION 著者 Dong, W.Y, Fu, Z.F, Peng, G.Q. 登録日 2014-11-19 公開日 2015-12-09 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (1.699 Å) 主引用文献 Crystal structural basis for Rv0315, an immunostimulatory antigen and inactive beta-1,3-glucanase of Mycobacterium tuberculosis. Sci Rep, 5, 2015
6AC8	Crystal structure of Mycobacterium smegmatis Mfd at 2.75 A resolution 分子名称: Mycobacterium smegmatis Mfd, SULFATE ION 著者 Putta, S, Fox, G.C, Walsh, M.A, Rao, D.N, Nagaraja, V, Natesh, R. 登録日 2018-07-25 公開日 2019-08-28 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.75 Å) 主引用文献 Structural basis for nucleotide-mediated remodelling mechanism of Mycobacterium Mfd To Be Published
3M6C	Crystal structure of Mycobacterium tuberculosis GroEL1 apical domain 分子名称: 60 kDa chaperonin 1 著者 Tsai, F.T.F, Sielaff, B, Lee, K. 登録日 2010-03-15 公開日 2010-12-08 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structural and functional conservation of Mycobacterium tuberculosis GroEL paralogs suggests that GroEL1 Is a chaperonin. J.Mol.Biol., 405, 2011
3N76	Crystal structure of 3-dehydroquinate dehydratase from Mycobacterium tuberculosis in complex with compound 5 分子名称: (1S,3R,4R,5S)-1,3,4-TRIHYDROXY-5-(3-PHENOXYPROPYL)CYCLOHEXANECARBOXYLIC ACID, 3-dehydroquinate dehydratase 著者 Dias, M.V.B, Snee, W.C, Bromfield, K.M, Payne, R, Palaninathan, S.K, Ciulli, A, Howard, N.I, Abell, C, Sacchettini, J.C, Blundell, T.L. 登録日 2010-05-26 公開日 2011-05-11 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structural investigation of inhibitor designs targeting 3-dehydroquinate dehydratase from the shikimate pathway of Mycobacterium tuberculosis. Biochem.J., 436, 2011
3N86	Crystal structure of 3-dehydroquinate dehydratase from Mycobacterium tuberculosis in complex with inhibitor 4 分子名称: (1R,5R)-1,5-dihydroxy-4-oxo-3-[3-oxo-3-(phenylamino)propyl]cyclohex-2-ene-1-carboxylic acid, 3-dehydroquinate dehydratase 著者 Dias, M.V.B, Snee, W.C, Bromfield, K.M, Payne, R, Palaninathan, S.K, Ciulli, A, Howard, N.I, Abell, C, Sacchettini, J.C, Blundell, T.L. 登録日 2010-05-27 公開日 2011-05-11 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structural investigation of inhibitor designs targeting 3-dehydroquinate dehydratase from the shikimate pathway of Mycobacterium tuberculosis. Biochem.J., 436, 2011

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