6E05
Crystal structure of Mycobacterium tuberculosis dethiobiotin synthetase in complex with cytidine triphosphate solved by precipitant-ligand exchange (crystals grown in sulfate precipitant)
Summary for 6E05
Entry DOI | 10.2210/pdb6e05/pdb |
Related | 3FGN 3FMF 3FMI 3FPA 4WOP 6CVE 6CVF 6CVU 6CVV 6CZB 6CZC 6CZD 6CZE 6E06 |
Descriptor | ATP-dependent dethiobiotin synthetase BioD, MAGNESIUM ION, CYTIDINE-5'-TRIPHOSPHATE, ... (4 entities in total) |
Functional Keywords | enzyme, synthetase, nucleotide triphosphate binding, transferase |
Biological source | Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) |
Total number of polymer chains | 4 |
Total formula weight | 95925.50 |
Authors | Thompson, A.P.,Wegener, K.L.,Bruning, J.B.,Polyak, S.W. (deposition date: 2018-07-06, release date: 2018-10-17, Last modification date: 2023-10-11) |
Primary citation | Thompson, A.P.,Wegener, K.L.,Booker, G.W.,Polyak, S.W.,Bruning, J.B. Precipitant-ligand exchange technique reveals the ADP binding mode in Mycobacterium tuberculosis dethiobiotin synthetase. Acta Crystallogr D Struct Biol, 74:965-972, 2018 Cited by PubMed: 30289406DOI: 10.1107/S2059798318010136 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
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