PDB: 41592 件ウェブページステータス検索Chemie searchBIRD

---

4UM1	Engineered Ls-AChBP with alpha4-alpha4 binding pocket in complex with NS3573 分子名称: 1-(5-ethoxypyridin-3-yl)-1,4-diazepane, 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETYLCHOLINE-BINDING PROTEIN 著者 Shahsavar, A, Kastrup, J.S, Balle, T, Gajhede, M. 登録日 2014-05-14 公開日 2015-07-22 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.83 Å) 主引用文献 Achbp Engineered to Mimic the Alpha4-Alpha4 Binding Pocket in Alpha4Beta2 Nicotinic Acetylcholine Receptors Reveals Interface Specific Interactions Important for Binding and Activity Mol.Pharmacol., 88, 2015
1YTQ	Structure of Native Human Beta B2 Crystallin 分子名称: Beta crystallin B2 著者 Slingsby, C, Smith, M.A, Bateman, O.A. 登録日 2005-02-10 公開日 2006-01-31 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Mutation of interfaces in domain-swapped human betaB2-crystallin Protein Sci., 16, 2007
4MZQ	beta-Alanyl-CoA:Ammonia Lyase from Clostridium propionicum in complex with propionyl-CoA 分子名称: beta-Alanyl-CoA:Ammonia Lyase, propionyl Coenzyme A 著者 Heine, A, Reuter, K. 登録日 2013-09-30 公開日 2014-03-26 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.587 Å) 主引用文献 High resolution crystal structure of Clostridium propionicum beta-alanyl-CoA:ammonia lyase, a new member of the "hot dog fold" protein superfamily. Proteins, 82, 2014
6NB9	Amyloid-Beta (20-34) with L-isoaspartate 23 分子名称: Amyloid-beta A4 protein 著者 Sawaya, M.R, Warmack, R.A, Boyer, D.R, Zee, C.T, Richards, L.S, Cascio, D, Gonen, T, Clarke, S.G, Eisenberg, D.S. 登録日 2018-12-06 公開日 2019-08-07 最終更新日 2022-09-07 実験手法 ELECTRON CRYSTALLOGRAPHY (1.05 Å) 主引用文献 Structure of amyloid-beta (20-34) with Alzheimer's-associated isomerization at Asp23 reveals a distinct protofilament interface. Nat Commun, 10, 2019
4PTZ	Crystal structure of the Escherichia coli alkanesulfonate FMN reductase SsuE in FMN-bound form 分子名称: FLAVIN MONONUCLEOTIDE, FMN reductase SsuE, GLYCEROL, ... 著者 Driggers, C.M, Ellis, H.R, Karplus, P.A. 登録日 2014-03-11 公開日 2014-06-18 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.9007 Å) 主引用文献 Crystal Structure of Escherichia coli SsuE: Defining a General Catalytic Cycle for FMN Reductases of the Flavodoxin-like Superfamily. Biochemistry, 53, 2014
6OIZ	Amyloid-Beta (20-34) wild type 分子名称: Amyloid beta A4 protein 著者 Sawaya, M.R, Warmack, R.A, Zee, C.T, Gonen, T, Clarke, S.G, Eisenberg, D.S. 登録日 2019-04-10 公開日 2019-08-07 最終更新日 2024-05-15 実験手法 ELECTRON CRYSTALLOGRAPHY (1.1 Å) 主引用文献 Structure of amyloid-beta (20-34) with Alzheimer's-associated isomerization at Asp23 reveals a distinct protofilament interface. Nat Commun, 10, 2019
4PU0	Crystal structure of the Escherichia coli alkanesulfonate FMN reductase SsuE in FMNH2-bound form 分子名称: FLAVIN MONONUCLEOTIDE, FMN reductase SsuE, GLYCEROL, ... 著者 Driggers, C.M, Ellis, H.R, Karplus, P.A. 登録日 2014-03-11 公開日 2014-06-18 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.3018 Å) 主引用文献 Crystal Structure of Escherichia coli SsuE: Defining a General Catalytic Cycle for FMN Reductases of the Flavodoxin-like Superfamily. Biochemistry, 53, 2014
5IZ2	Crystal structure of the N. clavipes spidroin NTD at pH 6.5 分子名称: Major ampullate spidroin 1A, Major ampullate spidroin 1A (Partial C-terminus) 著者 Atkison, J.H, Olsen, S.K. 登録日 2016-03-24 公開日 2016-07-27 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.02 Å) 主引用文献 Crystal Structure of the Nephila clavipes Major Ampullate Spidroin 1A N-terminal Domain Reveals Plasticity at the Dimer Interface. J.Biol.Chem., 291, 2016
4PTY	Crystal structure of the Escherichia coli alkanesulfonate FMN reductase SsuE in apo form 分子名称: FMN reductase SsuE, GLYCEROL, PHOSPHATE ION 著者 Driggers, C.M, Ellis, H.R, Karplus, P.A. 登録日 2014-03-11 公開日 2014-06-18 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Crystal Structure of Escherichia coli SsuE: Defining a General Catalytic Cycle for FMN Reductases of the Flavodoxin-like Superfamily. Biochemistry, 53, 2014
7PJM	Crystal Structure of Ivosidenib-resistant IDH1 variant R132C S280F in complex with NADPH and Ca2+/2-Oxoglutarate 分子名称: 2-OXOGLUTARIC ACID, CALCIUM ION, CHLORIDE ION, ... 著者 Reinbold, R, Rabe, P, Abboud, M.I, Schofield, C.J. 登録日 2021-08-24 公開日 2022-07-13 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Resistance to the isocitrate dehydrogenase 1 mutant inhibitor ivosidenib can be overcome by alternative dimer-interface binding inhibitors. Nat Commun, 13, 2022
7PJN	Crystal Structure of Ivosidenib-resistant IDH1 variant R132C S280F in complex with NADPH and inhibitor DS-1001B 分子名称: (E)-3-(1-(5-(2-fluoropropan-2-yl)-3-(2,4,6-trichlorophenyl)isoxazole-4-carbonyl)-3-methyl-1H-indol-4-yl)acrylic acid, CITRIC ACID, GLYCEROL, ... 著者 Reinbold, R, Rabe, P, Abboud, M.I, Schofield, C.J, Clifton, I.J. 登録日 2021-08-24 公開日 2022-07-13 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.45 Å) 主引用文献 Resistance to the isocitrate dehydrogenase 1 mutant inhibitor ivosidenib can be overcome by alternative dimer-interface binding inhibitors. Nat Commun, 13, 2022
6TB0	Crystal structure of thermostable omega transaminase 4-fold mutant from Pseudomonas jessenii 分子名称: Aspartate aminotransferase family protein, GLYCEROL, PYRIDOXAL-5'-PHOSPHATE, ... 著者 Capra, N, Rozeboom, H.J, Thunnissen, A.M.W.H, Janssen, D.B. 登録日 2019-10-31 公開日 2020-07-15 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Robust omega-Transaminases by Computational Stabilization of the Subunit Interface. Acs Catalysis, 10, 2020
6TB1	Crystal structure of thermostable omega transaminase 6-fold mutant from Pseudomonas jessenii 分子名称: Aspartate aminotransferase family protein, GLYCEROL, PYRIDOXAL-5'-PHOSPHATE, ... 著者 Capra, N, Rozeboom, H.J, Thunnissen, A.M.W.H, Janssen, D.B. 登録日 2019-10-31 公開日 2020-07-15 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Robust omega-Transaminases by Computational Stabilization of the Subunit Interface. Acs Catalysis, 10, 2020
6WLE	Crystal structure of the Zeitlupe light-state mimic G46A 分子名称: 1,2-ETHANEDIOL, Adagio protein 1, FLAVIN MONONUCLEOTIDE 著者 Zoltowski, B, Green, R. 登録日 2020-04-20 公開日 2021-03-03 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Steric and Electronic Interactions at Gln154 in ZEITLUPE Induce Reorganization of the LOV Domain Dimer Interface. Biochemistry, 60, 2021
6WLP	Crystal Structure of the ZTL light-state mimic G46S 分子名称: 1,2-ETHANEDIOL, Adagio protein 1, FLAVIN MONONUCLEOTIDE 著者 Zoltowski, B, Green, R. 登録日 2020-04-20 公開日 2021-03-03 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Steric and Electronic Interactions at Gln154 in ZEITLUPE Induce Reorganization of the LOV Domain Dimer Interface. Biochemistry, 60, 2021
4UM3	Engineered Ls-AChBP with alpha4-alpha4 binding pocket in complex with NS3920 分子名称: 1-(6-bromopyridin-3-yl)-1,4-diazepane, 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETYLCHOLINE BINDING PROTEIN, ... 著者 Shahsavar, A, Kastrup, J.S, Balle, T, Gajhede, M. 登録日 2014-05-14 公開日 2015-07-22 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.703 Å) 主引用文献 Achbp Engineered to Mimic the Alpha4-Alpha4 Binding Pocket in Alpha4Beta2 Nicotinic Acetylcholine Receptors Reveals Interface Specific Interactions Important for Binding and Activity Mol.Pharmacol., 88, 2015
6RWH	Fragment AZ-007 binding at a primary and secondary binding site of the the p53pT387/14-3-3 sigma complex 分子名称: 14-3-3 protein sigma, 5-(1~{H}-imidazol-5-yl)-4-phenyl-thiophene-2-carboximidamide, CALCIUM ION, ... 著者 Leysen, S, Guillory, X, Wolter, M, Genet, S, Somsen, B, Patel, J, Castaldi, P, Ottmann, C. 登録日 2019-06-05 公開日 2020-06-17 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.68 Å) 主引用文献 Fragment-based Differential Targeting of PPI Stabilizer Interfaces. J.Med.Chem., 63, 2020
5LVE	STRUCTURE OF THE VARIABLE DOMAIN OF HUMAN IMMUNOGLOBULIN K-4 LIGHT CHAIN LEN 分子名称: BENCE-JONES PROTEIN LEN, ZINC ION 著者 Schiffer, M, Huang, D.-B, Chang, C.-H. 登録日 1999-02-24 公開日 2000-02-18 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Change in dimerization mode by removal of a single unsatisfied polar residue located at the interface. Protein Sci., 9, 2000
6S9Q	Fragment AZ-004 binding at a primary and secondary site in a p53pT387/14-3-3 complex 分子名称: 14-3-3 protein sigma, 4-methyl-5-phenyl-thiophene-2-carboximidamide, CALCIUM ION, ... 著者 Leysen, S, Guillory, X, Wolter, M, Genet, S, Somsen, B, Patel, J, Castaldi, P, Ottmann, C. 登録日 2019-07-15 公開日 2020-06-17 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.69 Å) 主引用文献 Fragment-based Differential Targeting of PPI Stabilizer Interfaces. J.Med.Chem., 63, 2020
1MUD	CATALYTIC DOMAIN OF MUTY FROM ESCHERICHIA COLI, D138N MUTANT COMPLEXED TO ADENINE 分子名称: ADENINE, Adenine DNA glycosylase, GLYCEROL, ... 著者 Guan, Y, Tainer, J.A. 登録日 1998-08-20 公開日 1999-09-20 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 MutY catalytic core, mutant and bound adenine structures define specificity for DNA repair enzyme superfamily. Nat.Struct.Biol., 5, 1998
3FG6	Structure of the C-terminus of Adseverin 分子名称: Adseverin, CALCIUM ION 著者 Robinson, R.C. 登録日 2008-12-05 公開日 2009-08-11 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 The crystal structure of the C-terminus of adseverin reveals the actin-binding interface. Proc.Natl.Acad.Sci.USA, 106, 2009
4OEJ	Structure of membrane binding protein pleurotolysin B from Pleurotus ostreatus 分子名称: ACETATE ION, CHLORIDE ION, GLYCEROL, ... 著者 Dunstone, M.A, Caradoc-Davies, T.T, Whisstock, J.C, Law, R.H.P. 登録日 2014-01-13 公開日 2015-02-18 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Conformational Changes during Pore Formation by the Perforin-Related Protein Pleurotolysin. Plos Biol., 13, 2015
5KEH	Truncated hemolysin A from P. mirabilis at 2.0 Angstroms resolution crystallized in a high salt condition 分子名称: Hemolysin 著者 Novak, W.R.P, Bhattacharyya, B, Weaver, T.M. 登録日 2016-06-09 公開日 2017-03-22 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.551 Å) 主引用文献 Proteolysis of truncated hemolysin A yields a stable dimerization interface. Acta Crystallogr F Struct Biol Commun, 73, 2017
5KF3	Truncated hemolysin A from P. mirabilis Y134A at 2.2 Angstroms resolution 分子名称: Hemolysin 著者 Novak, W.R.P, Bhattacharyya, B, Weaver, T.M. 登録日 2016-06-11 公開日 2017-03-22 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Proteolysis of truncated hemolysin A yields a stable dimerization interface. Acta Crystallogr F Struct Biol Commun, 73, 2017
4OEB	Structure of membrane binding protein pleurotolysin A from Pleurotus ostreatus 分子名称: Pleurotolysin A, SULFATE ION 著者 Dunstone, M.A, Caradoc-Davies, T.T, Whisstock, J.C, Law, R.H.P. 登録日 2014-01-12 公開日 2015-02-18 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Conformational Changes during Pore Formation by the Perforin-Related Protein Pleurotolysin. Plos Biol., 13, 2015

<32333435363738394041424344454647>