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4WF1
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BU of 4wf1 by Molmil
Crystal structure of the E. coli ribosome bound to negamycin.
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
著者Olivier, N.B, Altman, R.B, Noeske, J, Basarab, G.S, Code, E, Ferguson, A.D, Gao, N, Huang, J, Juette, M.F, Livchak, S, Miller, M.D, Prince, D.B, Cate, J.H.D, Buurman, E.T, Blanchard, S.C.
登録日2014-09-11
公開日2014-11-05
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (3.09 Å)
主引用文献Negamycin induces translational stalling and miscoding by binding to the small subunit head domain of the Escherichia coli ribosome.
Proc.Natl.Acad.Sci.USA, 111, 2014
5WSX
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BU of 5wsx by Molmil
The crystal structure of SAV606
分子名称: Uncharacterized protein
著者Chisuga, T, Miyanaga, A, Kudo, F, Eguchi, T.
登録日2016-12-08
公開日2017-05-31
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural analysis of the dual-function thioesterase SAV606 unravels the mechanism of Michael addition of glycine to an alpha , beta-unsaturated thioester.
J. Biol. Chem., 292, 2017
5X1K
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BU of 5x1k by Molmil
Vanillate/3-O-methylgallate O-demethylase, LigM, 3-O-methylgallate complex form
分子名称: 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 3-methoxy-4,5-bis(oxidanyl)benzoic acid, ...
著者Harada, A, Senda, T.
登録日2017-01-26
公開日2017-05-17
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献The crystal structure of a new O-demethylase from Sphingobium sp. strain SYK-6
FEBS J., 284, 2017
5WNB
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BU of 5wnb by Molmil
Structure of antibody 3D3 bound to the linear epitope of RSV G
分子名称: ACETIC ACID, Major surface glycoprotein G, ZINC ION, ...
著者Fedechkin, S.O, George, N.L, Wolff, J.T, Kauvar, L.M, DuBois, R.M.
登録日2017-07-31
公開日2018-03-14
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structures of respiratory syncytial virus G antigen bound to broadly neutralizing antibodies.
Sci Immunol, 3, 2018
5WNW
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BU of 5wnw by Molmil
Chaperone Spy bound to Im7 6-45 ensemble
分子名称: CHLORIDE ION, Colicin-E7 immunity protein, IMIDAZOLE, ...
著者Horowitz, S, Salmon, L, Koldewey, P, Ahlstrom, L.S, Martin, R, Xu, Q, Afonine, P.V, Trievel, R.C, Brooks, C.L, Bardwell, J.C.A.
登録日2017-08-01
公開日2017-08-16
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.79 Å)
主引用文献Visualizing chaperone-assisted protein folding.
Nat. Struct. Mol. Biol., 23, 2016
4WSK
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BU of 4wsk by Molmil
Crystal structure of a bacterial fucosidase with phenyl((1R,2R,3R,4R,5R,6R)-2,3,4-trihydroxy-5-methyl-7-azabicyclo[4.1.0]heptan-7-yl)methanone
分子名称: Alpha-L-fucosidase, IMIDAZOLE, N-[(1S,2R,3R,4S,5R)-3,4,5-trihydroxy-2-methylcyclohexyl]benzamide, ...
著者Davies, G.J.
登録日2014-10-28
公開日2014-11-12
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.92 Å)
主引用文献In vitroandin vivocomparative and competitive activity-based protein profiling of GH29 alpha-l-fucosidases.
Chem Sci, 6, 2015
4WSP
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BU of 4wsp by Molmil
Racemic crystal structure of Rv1738 from Mycobacterium tuberculosis (Form-I)
分子名称: CHLORIDE ION, protein DL-Rv1738
著者Bunker, R.D, Mandal, K, Kent, S.B.H, Baker, E.N.
登録日2014-10-28
公開日2015-03-18
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献A functional role of Rv1738 in Mycobacterium tuberculosis persistence suggested by racemic protein crystallography.
Proc.Natl.Acad.Sci.USA, 112, 2015
4WSQ
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BU of 4wsq by Molmil
Crystal Structure of Adaptor Protein 2 Associated Kinase (AAK1) in complex with small molecule inhibitor
分子名称: 1,2-ETHANEDIOL, AP2-associated protein kinase 1, K-252A, ...
著者Sorrell, F.J, Elkins, J.M, Krojer, T, Williams, E, Abdul, K, Gileadi, O, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Knapp, S, Structural Genomics Consortium (SGC)
登録日2014-10-28
公開日2014-11-05
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Family-wide Structural Analysis of Human Numb-Associated Protein Kinases.
Structure, 24, 2016
4WT7
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BU of 4wt7 by Molmil
Crystal structure of an ABC transporter solute binding protein (IPR025997) from Agrobacterium vitis (Avi_5165, Target EFI-511223) with bound allitol
分子名称: ABC transporter substrate binding protein (Ribose), CHLORIDE ION, D-allitol
著者Vetting, M.W, Al Obaidi, N.F, Toro, R, Morisco, L.L, Benach, J, Wasserman, S.R, Attonito, J.D, Scott Glenn, A, Chamala, S, Chowdhury, S, Lafleur, J, Love, J, Seidel, R.D, Whalen, K.L, Gerlt, J.A, Almo, S.C, Enzyme Function Initiative (EFI)
登録日2014-10-29
公開日2014-11-12
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structure of an ABC transporter solute binding protein (IPR025997) from Agrobacterium vitis (Avi_5165, Target EFI-511223) with bound allitol
To be published
4WVI
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BU of 4wvi by Molmil
Crystal structure of the Type-I signal peptidase from Staphylococcus aureus (SpsB) in complex with a substrate peptide (pep2).
分子名称: Maltose-binding periplasmic protein,Signal peptidase IB, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, substrate peptide (pep2)
著者Young, P.G, Ting, Y.T, Baker, E.N.
登録日2014-11-05
公開日2015-09-23
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Peptide binding to a bacterial signal peptidase visualized by peptide tethering and carrier-driven crystallization.
IUCrJ, 3, 2016
4YEU
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BU of 4yeu by Molmil
ELIC-GLIC chimera in the resting conformation
分子名称: Cys-loop ligand-gated ion channel,Proton-gated ion channel
著者Schmandt, N, Vivien, Y, Lodowski, D, Chakrapani, S.
登録日2015-02-24
公開日2015-09-16
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (4.6 Å)
主引用文献An ELIC-GLIC Chimera Reveals Distinct Pathways of Activation in the Cys-loop receptors
To Be Published
4YRJ
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BU of 4yrj by Molmil
Crystal structure of T. cruzi Histidyl-tRNA synthetase in complex with 4-chlorobenzene-1,2-diamine (Chem 256)
分子名称: 1,2-ETHANEDIOL, 4-chlorobenzene-1,2-diamine, DIMETHYL SULFOXIDE, ...
著者Koh, C.-Y, Hol, W.G.J.
登録日2015-03-15
公開日2015-08-12
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献A binding hotspot in Trypanosoma cruzi histidyl-tRNA synthetase revealed by fragment-based crystallographic cocktail screens.
Acta Crystallogr. D Biol. Crystallogr., 71, 2015
4YRS
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BU of 4yrs by Molmil
Crystal structure of T. cruzi Histidyl-tRNA synthetase in complex with N-(quinolin-3-yl)propanamide (Chem 1698)
分子名称: HISTIDINE, Histidyl-tRNA synthetase, N-(quinolin-3-yl)propanamide
著者Koh, C.-Y, Hol, W.G.J.
登録日2015-03-15
公開日2015-08-12
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献A binding hotspot in Trypanosoma cruzi histidyl-tRNA synthetase revealed by fragment-based crystallographic cocktail screens.
Acta Crystallogr. D Biol. Crystallogr., 71, 2015
4YSM
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BU of 4ysm by Molmil
Calcium-Dependent Protein Kinase from Eimeria tenella
分子名称: CALCIUM ION, Calmodulin-like domain protein kinase
著者Merritt, E.A.
登録日2015-03-17
公開日2016-04-06
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.19 Å)
主引用文献CDPK is a druggable target in the apicomplexan parasite Eimeria
to be published
4YUR
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BU of 4yur by Molmil
Crystal Structure of Plk4 Kinase Domain Bound to Centrinone
分子名称: 2-({2-fluoro-4-[(2-fluoro-3-nitrobenzyl)sulfonyl]phenyl}sulfanyl)-5-methoxy-N-(3-methyl-1H-pyrazol-5-yl)-6-(morpholin-4-yl)pyrimidin-4-amine, Serine/threonine-protein kinase PLK4
著者Shiau, A.K, Motamedi, A.
登録日2015-03-19
公開日2015-06-17
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Cell biology. Reversible centriole depletion with an inhibitor of Polo-like kinase 4.
Science, 348, 2015
5WGL
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BU of 5wgl by Molmil
Crystal structure of Danio rerio histone deacetylase 6 catalytic domain 2 in complex with ricolinostat (ACY-1215)
分子名称: 1,2-ETHANEDIOL, 2-(diphenylamino)-N-[7-(hydroxyamino)-7-oxoheptyl]pyrimidine-5-carboxamide, CITRATE ANION, ...
著者Porter, N.J, Christianson, D.W.
登録日2017-07-14
公開日2017-12-06
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Unusual zinc-binding mode of HDAC6-selective hydroxamate inhibitors.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
4YKB
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BU of 4ykb by Molmil
Structure of GUN4 from Chlamydomonas reinhardtii
分子名称: Tetrapyrrole-binding protein
著者Tabriz, S.T, Langley, D.B, Willows, R.D, Duff, A.P, Harrop, S.J.
登録日2015-03-04
公開日2015-08-12
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Structure of GUN4 from Chlamydomonas reinhardtii.
Acta Crystallogr F Struct Biol Commun, 71, 2015
4YLI
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BU of 4yli by Molmil
CL-K1 trimer
分子名称: CALCIUM ION, CHLORIDE ION, Collectin-11, ...
著者Wallis, R, Girija, U.V, Gingras, A.R, Moody, P.C.E, Marshall, J.E.
登録日2015-03-05
公開日2015-04-08
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Molecular basis of sugar recognition by collectin-K1 and the effects of mutations associated with 3MC syndrome.
Bmc Biol., 13, 2015
4YWO
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BU of 4ywo by Molmil
Mercuric reductase from Metallosphaera sedula
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, Mercuric reductase
著者Artz, J.H, Zadvornyy, O.A, White, S, Peters, J.W.
登録日2015-03-20
公開日2015-09-16
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.62 Å)
主引用文献Biochemical and Structural Properties of a Thermostable Mercuric Ion Reductase from Metallosphaera sedula.
Front Bioeng Biotechnol, 3, 2015
4YX6
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BU of 4yx6 by Molmil
Architectural hierarchy of trans-acting enoyl reductases from polyunsaturated fatty acid and trans-AT polyketide synthases
分子名称: CALCIUM ION, FLAVIN MONONUCLEOTIDE, Omega-3 polyunsaturated fatty acid synthase subunit PfaD
著者Till, M, Race, P.R.
登録日2015-03-22
公開日2016-04-13
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.86 Å)
主引用文献Architectural hierarchy of trans-acting enoyl reductases from polyunsaturated fatty acid and trans-AT polyketide synthases
To Be Published
4YMR
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BU of 4ymr by Molmil
Crystal structure of the domain swapped PXB/TPR domain of mouse SNX21
分子名称: Protein Snx21
著者Collins, B.C, Teasdale, R.D, Clairfeuille, T.
登録日2015-03-07
公開日2015-04-29
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structure and Membrane Binding Properties of the Endosomal Tetratricopeptide Repeat (TPR) Domain-containing Sorting Nexins SNX20 and SNX21.
J.Biol.Chem., 290, 2015
4YMH
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BU of 4ymh by Molmil
Crystal structure of SAH-bound Podospora anserina methyltransferase PaMTH1
分子名称: DI(HYDROXYETHYL)ETHER, Putative SAM-dependent O-methyltranferase, S-ADENOSYL-L-HOMOCYSTEINE
著者Kudlinzki, D, Linhard, V.L, Chatterjee, D, Saxena, K, Sreeramulu, S, Schwalbe, H.
登録日2015-03-06
公開日2015-05-27
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.876 Å)
主引用文献Structure and Biophysical Characterization of the S-Adenosylmethionine-dependent O-Methyltransferase PaMTH1, a Putative Enzyme Accumulating during Senescence of Podospora anserina.
J.Biol.Chem., 290, 2015
4YOS
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BU of 4yos by Molmil
p107 pocket domain complexed with LIN52 peptide
分子名称: 1,2-ETHANEDIOL, Protein lin-52 homolog, Retinoblastoma-like protein 1,Retinoblastoma-like protein 1, ...
著者Guiley, K.Z, Liban, T.J, Felthousen, J.G, Ramanan, P, Tripathi, S, Litovchick, L, Rubin, S.M.
登録日2015-03-12
公開日2015-05-27
最終更新日2019-12-04
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural mechanisms of DREAM complex assembly and regulation.
Genes Dev., 29, 2015
5WX4
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BU of 5wx4 by Molmil
Alkylquinolone synthase from Evodia rutaecarpa
分子名称: alkylquinolone synthase
著者Matsui, T, Kodama, T, Tadakoshi, T, Morita, H.
登録日2017-01-06
公開日2017-04-26
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.203 Å)
主引用文献2-Alkylquinolone alkaloid biosynthesis in the medicinal plant Evodia rutaecarpa involves collaboration of two novel type III polyketide synthases
J. Biol. Chem., 292, 2017
4YPF
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BU of 4ypf by Molmil
Crystal structure of T. cruzi Histidyl-tRNA synthetase in complex with quinolin-3-amine (Chem 84)
分子名称: 1,2-ETHANEDIOL, DIMETHYL SULFOXIDE, HISTIDINE, ...
著者Koh, C.-Y, Hol, W.G.J.
登録日2015-03-12
公開日2015-08-12
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献A binding hotspot in Trypanosoma cruzi histidyl-tRNA synthetase revealed by fragment-based crystallographic cocktail screens.
Acta Crystallogr. D Biol. Crystallogr., 71, 2015

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