PDB: 66507 件ウェブページステータス検索Chemie searchBIRD

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4DHR	Small-molecule inhibitors of 14-3-3 protein-protein interactions from virtual screening 分子名称: (2-{2-[(2-chlorophenyl)amino]-2-oxoethoxy}phenyl)phosphonic acid, 14-3-3 protein sigma, CHLORIDE ION, ... 著者 Thiel, P, Roeglin, L, Kohlbacher, O, Ottmann, C. 登録日 2012-01-30 公開日 2013-07-31 最終更新日 2013-09-04 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Virtual screening and experimental validation reveal novel small-molecule inhibitors of 14-3-3 protein-protein interactions. Chem.Commun.(Camb.), 49, 2013
4LTM	Crystal structures of NADH:FMN oxidoreductase (EMOB) - FMN complex 分子名称: FLAVIN MONONUCLEOTIDE, NADH-dependent FMN reductase, SULFATE ION 著者 Nissen, M.S, Youn, B, Knowles, B.D, Ballinger, J.W, Jun, S, Belchik, S.M, Xun, L, Kang, C. 登録日 2013-07-23 公開日 2013-08-07 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (2.497 Å) 主引用文献 Crystal structures of NADH:FMN oxidoreductase (EmoB) at different stages of catalysis. J.Biol.Chem., 283, 2008
3O1F	P1 crystal form of E. coli ClpS at 1.4 A resolution 分子名称: ATP-dependent Clp protease adapter protein clpS 著者 Roman-Hernandez, G, Hou, J.Y, Grant, R.A, Sauer, R.T, Baker, T.A. 登録日 2010-07-21 公開日 2011-07-27 最終更新日 2017-11-08 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 The ClpS Adaptor Mediates Staged Delivery of N-End Rule Substrates to the AAA+ ClpAP Protease. Mol.Cell, 43, 2011
8S9Z	Mpro inhibitors of SARS-CoV-2 分子名称: 3C-like proteinase nsp5, Mpro inhibitor 著者 Blankenship, L.R, Liu, W.R. 登録日 2023-03-30 公開日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Structure of MPI89 with Mpro of SARS-CoV-2 at 1.85A resolution. To Be Published
4DXF	Crystal structure of Staphylococcal Superantigen-Like protein 4 分子名称: CHLORIDE ION, GLYCEROL, Staphylococcal enterotoxin-like toxin 著者 Hermans, S.J, Baker, H.M, Langley, R.J, Baker, E.N, Fraser, J.F. 登録日 2012-02-27 公開日 2012-09-19 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Structural and functional properties of staphylococcal superantigen-like protein 4 Infect.Immun., 80, 2012
8SLV	Structure of a salivary alpha-glucosidase from the mosquito vector Aedes aegypti. 分子名称: 1,3-PROPANDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Gittis, A.G, Williams, A.E, Garboczi, D, Calvo, E. 登録日 2023-04-24 公開日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.32 Å) 主引用文献 Structural and functional comparisons of salivary alpha-glucosidases from the mosquito vectors Aedes aegypti, Anopheles gambiae, and Culex quinquefasciatus. Insect Biochem.Mol.Biol., 167, 2024
4MJV	Influenza Neuraminidase in complex with a novel antiviral compound 分子名称: (2E,5S,9R,10S)-10-(acetylamino)-2-imino-4-oxo-9-(pentan-3-yloxy)-1-thia-3-azaspiro[4.5]dec-6-ene-7-carboxylic acid, CALCIUM ION, Neuraminidase 著者 Kerry, P.S. 登録日 2013-09-04 公開日 2014-01-15 最終更新日 2017-11-15 実験手法 X-RAY DIFFRACTION (2.65 Å) 主引用文献 Serendipitous discovery of a potent influenza virus a neuraminidase inhibitor. Angew.Chem.Int.Ed.Engl., 53, 2014
4MJ5	Crystal Structure of HLA-A*1101 in complex with H1-22, an influenza A(H1N1) virus epitope 分子名称: Beta-2-microglobulin, HLA class I histocompatibility antigen, A-11 alpha chain, ... 著者 Liu, J, Tan, S, Zhao, M, Qi, J, Gao, G.F. 登録日 2013-09-03 公開日 2014-10-08 最終更新日 2022-08-24 実験手法 X-RAY DIFFRACTION (2.401 Å) 主引用文献 Cross-immunity Against Avian Influenza A(H7N9) Virus in the Healthy Population Is Affected by Antigenicity-Dependent Substitutions. J.Infect.Dis., 214, 2016
4L2C	X-ray structure of the C57R mutant of the iron superoxide dismutase from Pseudoalteromonas haloplanktis (crystal form I) 分子名称: FE (III) ION, Superoxide dismutase [Fe], alpha-D-glucopyranose-(1-1)-alpha-D-glucopyranose 著者 Russo Krauss, I, Merlino, A, Sica, F. 登録日 2013-06-04 公開日 2014-02-26 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.66 Å) 主引用文献 Structural and denaturation studies of two mutants of a cold adapted superoxide dismutase point to the importance of electrostatic interactions in protein stability. Biochim.Biophys.Acta, 1844, 2014
4DHP	Small-molecule inhibitors of 14-3-3 protein-protein interactions from virtual screening 分子名称: 14-3-3 protein sigma, CHLORIDE ION, GLYCEROL, ... 著者 Thiel, P, Roeglin, L, Kohlbacher, O, Ottmann, C. 登録日 2012-01-30 公開日 2013-07-31 最終更新日 2013-09-04 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Virtual screening and experimental validation reveal novel small-molecule inhibitors of 14-3-3 protein-protein interactions. Chem.Commun.(Camb.), 49, 2013
3OA1	Crystal structure of phosphoprotein/Protein P/Protein M1 residues 69-297 from Rabies virus reveals degradation to C-terminal domain only 分子名称: Phosphoprotein, SULFATE ION 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2010-08-04 公開日 2010-08-18 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Crystal structure of phosphoprotein/Protein P/Protein M1 residues 69-297 from Rabies virus reveals degradation to C-terminal domain only To be Published
4DXG	Crystal structure of Staphylococcal Superantigen-Like protein 4 complexed with sialyl Lewis X 分子名称: CHLORIDE ION, N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-4)-[alpha-L-fucopyranose-(1-3)]2-acetamido-2-deoxy-alpha-D-glucopyranose, PIPERAZINE-N,N'-BIS(2-ETHANESULFONIC ACID), ... 著者 Hermans, S.J, Baker, H.M, Langley, R.J, Baker, E.N, Fraser, J.F. 登録日 2012-02-27 公開日 2012-09-19 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structural and functional properties of staphylococcal superantigen-like protein 4 Infect.Immun., 80, 2012
4L1L	Rat PKC C2 domain bound to CD 分子名称: CADMIUM ION, Protein kinase C alpha type, SULFATE ION 著者 Morales, K.M, Yang, Y, Long, Z, Li, P, Taylor, A.B, Hart, P.J, Igumenova, T.I. 登録日 2013-06-03 公開日 2013-08-28 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Cd(2+) as a ca(2+) surrogate in protein-membrane interactions: isostructural but not isofunctional. J.Am.Chem.Soc., 135, 2013
4L55	X-ray structure of the adduct between bovine pancreatic ribonuclease and AziRu 分子名称: RUTHENIUM ION, Ribonuclease pancreatic 著者 Vergara, A, Russo Krauss, I, Merlino, A. 登録日 2013-06-10 公開日 2014-01-29 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Investigating the ruthenium metalation of proteins: X-ray structure and Raman microspectroscopy of the complex between RNase A and AziRu. Inorg.Chem., 52, 2013
4LEY	Structure of mouse cGAS bound to 18 bp DNA 分子名称: 18 bp dsDNA, Cyclic GMP-AMP synthase, ZINC ION 著者 Li, P. 登録日 2013-06-26 公開日 2013-12-25 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Cyclic GMP-AMP Synthase Is Activated by Double-Stranded DNA-Induced Oligomerization. Immunity, 39, 2013
8FDB	CRYSTAL STRUCTURE OF NAGB-II PHOSPHOSUGAR ISOMERASE FROM Shewanella denitrificans OS217 IN COMPLEX WITH GLUCITOLAMINE-6-PHOSPHATE AT 3.06 A RESOLUTION. 分子名称: 2-DEOXY-2-AMINO GLUCITOL-6-PHOSPHATE, GLYCEROL, Glutamine-fructose-6-phosphate transaminase (Isomerizing), ... 著者 Rodriguez-Romero, A, Rodriguez-Hernandez, A, Marcos-Viquez, J, Bustos-Jaimes, I. 登録日 2022-12-02 公開日 2023-05-17 最終更新日 2023-06-07 実験手法 X-RAY DIFFRACTION (3.06 Å) 主引用文献 Substrate binding in the allosteric site mimics homotropic cooperativity in the SIS-fold glucosamine-6-phosphate deaminases. Protein Sci., 32, 2023
8FO0	The structure of a crystallizable variant of E. coli pyruvate formate-lyase activating enzyme bound to a partially cleaved SAM molecule 分子名称: IRON/SULFUR CLUSTER, POTASSIUM ION, Pyruvate formate-lyase 1-activating enzyme, ... 著者 Moody, J.D, Saxton, A.J, Galambas, A, Lawrence, C.M, Broderick, J.B. 登録日 2022-12-29 公開日 2023-05-24 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (1.69 Å) 主引用文献 Computational engineering of previously crystallized pyruvate formate-lyase activating enzyme reveals insights into SAM binding and reductive cleavage. J.Biol.Chem., 299, 2023
8FOL	The structure of a crystallizable variant of E. coli pyruvate formate-lyase activating enzyme bound to SAM, alternate crystal form 分子名称: CHLORIDE ION, IRON/SULFUR CLUSTER, POTASSIUM ION, ... 著者 Moody, J.D, Saxton, A.J, Galambas, A, Lawrence, C.M, Broderick, J.B. 登録日 2022-12-31 公開日 2023-05-24 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (2.65 Å) 主引用文献 Computational engineering of previously crystallized pyruvate formate-lyase activating enzyme reveals insights into SAM binding and reductive cleavage. J.Biol.Chem., 299, 2023
4LNM	Structure of Escherichia coli Threonine Aldolase in Complex with Serine 分子名称: (5-HYDROXY-4,6-DIMETHYLPYRIDIN-3-YL)METHYL DIHYDROGEN PHOSPHATE, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CALCIUM ION, ... 著者 Safo, M.K, Contestabile, R, Remesh, S.G. 登録日 2013-07-11 公開日 2013-11-06 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 On the catalytic mechanism and stereospecificity of Escherichia coli l-threonine aldolase. Febs J., 281, 2014
3FHP	A neutron crystallographic analysis of a porcine 2Zn insulin at 2.0 A resolution 分子名称: Insulin, ZINC ION 著者 Iwai, W, Kurihara, K, Yamada, T, Kobayashi, Y, Ohnishi, Y, Tanaka, I, Takahashi, H, Niimura, N. 登録日 2008-12-09 公開日 2009-10-20 最終更新日 2023-11-01 実験手法 NEUTRON DIFFRACTION (2 Å) 主引用文献 A neutron crystallographic analysis of T6 porcine insulin at 2.1 A resolution Acta Crystallogr.,Sect.D, 65, 2009
4DTB	Crystal Structure of F95Y Aminoglycoside-2''-Phosphotransferase Type IVa in Complex with Guanosine 分子名称: APH(2'')-Id, CHLORIDE ION, GUANOSINE 著者 Shi, K, Berghuis, A.M. 登録日 2012-02-20 公開日 2012-03-07 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structural Basis for Dual Nucleotide Selectivity of Aminoglycoside 2''-Phosphotransferase IVa Provides Insight on Determinants of Nucleotide Specificity of Aminoglycoside Kinases. J.Biol.Chem., 287, 2012
8FP5	CDK2 liganded with ATP and Mg2+ 分子名称: 1,2-ETHANEDIOL, ADENOSINE-5'-TRIPHOSPHATE, Cyclin-dependent kinase 2, ... 著者 Schonbrunn, E, Sun, L. 登録日 2023-01-04 公開日 2023-05-31 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Development of allosteric and selective CDK2 inhibitors for contraception with negative cooperativity to cyclin binding. Nat Commun, 14, 2023
4LI3	Crystal Structure of O-Acetylserine Sulfhydrylase from Haemophilus influenzae in complex with high affinity inhibitory peptide from Serine acetyl transferase of Salmonella typhimurium 分子名称: Cysteine synthase, GLYCEROL, Serine acetyltransferase 著者 Singh, A.K, Ekka, M.K, Kaushik, A, Kumaran, S. 登録日 2013-07-02 公開日 2014-07-09 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (2.592 Å) 主引用文献 Crystal Structure of O-Acetylserine Sulfhydrylase from Haemophilus influenzae in complex with high affinity inhibitory peptide from Serine acetyl transferase of Salmonella typhimurium To be Published
8RRP	Insulin Icodec - A14E B16H B25H B29Ne-C20 diacid-LgGlu-2xAdo desB30 human insulin 分子名称: ACETATE ION, Insulin, Insulin B chain 著者 Schluckebier, G, Johansson, E. 登録日 2024-01-23 公開日 2024-07-10 最終更新日 2024-07-31 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Enhanced disulphide bond stability contributes to the once-weekly profile of insulin icodec. Nat Commun, 15, 2024
4MJ6	Crystal Structure of HLA-A*1101 in complex with H7-22, an influenza A(H7N9) virus epitope 分子名称: Beta-2-microglobulin, HLA class I histocompatibility antigen, A-11 alpha chain, ... 著者 Liu, J, Tan, S, Zhao, M, Qi, J, Gao, G.F. 登録日 2013-09-03 公開日 2014-10-08 最終更新日 2022-08-24 実験手法 X-RAY DIFFRACTION (2.57 Å) 主引用文献 Cross-immunity Against Avian Influenza A(H7N9) Virus in the Healthy Population Is Affected by Antigenicity-Dependent Substitutions. J.Infect.Dis., 214, 2016

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