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7GSH
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BU of 7gsh by Molmil
PanDDA Analysis group deposition -- Crystal structure of PTP1B in complex with FMOPL000530a
分子名称: 2-(4-methylphenyl)-N-{[(2S)-oxolan-2-yl]methyl}acetamide, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Tyrosine-protein phosphatase non-receptor type 1
著者Mehlman, T, Ginn, H.M, Keedy, D.A.
登録日2024-01-03
公開日2024-01-24
最終更新日2024-04-24
実験手法X-RAY DIFFRACTION (1.88 Å)
主引用文献An expanded view of ligandability in the allosteric enzyme PTP1B from computational reanalysis of large-scale crystallographic data.
Biorxiv, 2024
7GSG
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PanDDA Analysis group deposition -- Crystal structure of PTP1B in complex with FMOPL000316a
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Tyrosine-protein phosphatase non-receptor type 1, methyl 4-sulfamoylbenzoate
著者Mehlman, T, Ginn, H.M, Keedy, D.A.
登録日2024-01-03
公開日2024-01-24
最終更新日2024-04-24
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献An expanded view of ligandability in the allosteric enzyme PTP1B from computational reanalysis of large-scale crystallographic data.
Biorxiv, 2024
7GSJ
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PanDDA Analysis group deposition -- Crystal structure of PTP1B in complex with FMOPL000543a
分子名称: (phenylmethyl) 4-oxidanylpiperidine-1-carboxylate, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Tyrosine-protein phosphatase non-receptor type 1
著者Mehlman, T, Ginn, H.M, Keedy, D.A.
登録日2024-01-03
公開日2024-01-24
最終更新日2024-04-24
実験手法X-RAY DIFFRACTION (1.77 Å)
主引用文献An expanded view of ligandability in the allosteric enzyme PTP1B from computational reanalysis of large-scale crystallographic data.
Biorxiv, 2024
7GSX
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PanDDA Analysis group deposition -- Crystal structure of PTP1B in complex with FMSOA001440b
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 3-methyl-1-benzofuran-2-carboxylic acid, Tyrosine-protein phosphatase non-receptor type 1
著者Mehlman, T, Ginn, H.M, Keedy, D.A.
登録日2024-01-03
公開日2024-01-24
最終更新日2024-04-24
実験手法X-RAY DIFFRACTION (1.67 Å)
主引用文献An expanded view of ligandability in the allosteric enzyme PTP1B from computational reanalysis of large-scale crystallographic data.
Biorxiv, 2024
7GT8
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BU of 7gt8 by Molmil
PanDDA Analysis group deposition -- Crystal structure of PTP1B in complex with FMSOA001439b
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 5-chloranylthiophene-2-sulfonamide, Tyrosine-protein phosphatase non-receptor type 1
著者Mehlman, T, Ginn, H.M, Keedy, D.A.
登録日2024-01-03
公開日2024-01-24
最終更新日2024-04-24
実験手法X-RAY DIFFRACTION (1.91 Å)
主引用文献An expanded view of ligandability in the allosteric enzyme PTP1B from computational reanalysis of large-scale crystallographic data.
Biorxiv, 2024
2D0D
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BU of 2d0d by Molmil
Crystal Structure of a Meta-cleavage Product Hydrolase (CumD) A129V Mutant
分子名称: 2-hydroxy-6-oxo-7-methylocta-2,4-dienoate hydrolase, CHLORIDE ION, PHOSPHATE ION
著者Jun, S.Y, Fushinobu, S, Nojiri, H, Omori, T, Shoun, H, Wakagi, T.
登録日2005-08-01
公開日2006-06-06
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Improving the catalytic efficiency of a meta-cleavage product hydrolase (CumD) from Pseudomonas fluorescens IP01
Biochim.Biophys.Acta, 1764, 2006
7Z18
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E. coli C-P lyase bound to a PhnK ABC dimer and ATP
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Alpha-D-ribose 1-methylphosphonate 5-phosphate C-P lyase, Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnG, ...
著者Amstrup, S.K, Sofos, N, Karlsen, J.L, Skjerning, R.B, Boesen, T, Enghild, J.J, Hove-Jensen, B, Brodersen, D.E.
登録日2022-02-24
公開日2022-05-25
最終更新日2024-07-17
実験手法ELECTRON MICROSCOPY (1.98 Å)
主引用文献Structural remodelling of the carbon-phosphorus lyase machinery by a dual ABC ATPase.
Nat Commun, 14, 2023
2DD1
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BU of 2dd1 by Molmil
Three consecutive sheared GA pairs in 5'GGUGGAGGCU/3'PCCAAAGCCG
分子名称: 5'-R(*GP*CP*CP*GP*AP*AP*AP*CP*CP*(P5P))-3', 5'-R(*GP*GP*UP*GP*GP*AP*GP*GP*CP*U)-3'
著者Chen, G, Kennedy, S.D, Krugh, T.R, Turner, D.H.
登録日2006-01-19
公開日2006-06-13
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献An Alternating Sheared AA Pair and Elements of Stability for a Single Sheared Purine-Purine Pair Flanked by Sheared GA Pairs in RNA
Biochemistry, 45, 2006
7Z17
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BU of 7z17 by Molmil
E. coli C-P lyase bound to a PhnK ABC dimer in an open conformation
分子名称: Alpha-D-ribose 1-methylphosphonate 5-phosphate C-P lyase, Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnG, Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnH, ...
著者Amstrup, S.K, Sofos, N, Karlsen, J.L, Skjerning, R.B, Boesen, T, Enghild, J.J, Hove-Jensen, B, Brodersen, D.E.
登録日2022-02-24
公開日2022-05-25
最終更新日2024-07-17
実験手法ELECTRON MICROSCOPY (2.57 Å)
主引用文献Structural remodelling of the carbon-phosphorus lyase machinery by a dual ABC ATPase.
Nat Commun, 14, 2023
7YWD
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BU of 7ywd by Molmil
Human GDAP1 core domain, trigonal crystal form
分子名称: Ganglioside-induced differentiation-associated protein 1
著者Raasakka, A, Kursula, P.
登録日2022-02-13
公開日2022-06-08
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Structural insights into Charcot-Marie-Tooth disease-linked mutations in human GDAP1.
Febs Open Bio, 12, 2022
7Z15
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BU of 7z15 by Molmil
E. coli C-P lyase bound to a PhnK/PhnL dual ABC dimer and ADP + Pi
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Alpha-D-ribose 1-methylphosphonate 5-phosphate C-P lyase, ...
著者Amstrup, S.K, Sofos, N, Karlsen, J.L, Skjerning, R.B, Boesen, T, Enghild, J.J, Hove-Jensen, B, Brodersen, D.E.
登録日2022-02-24
公開日2022-06-22
最終更新日2024-07-17
実験手法ELECTRON MICROSCOPY (1.93 Å)
主引用文献Structural remodelling of the carbon-phosphorus lyase machinery by a dual ABC ATPase.
Nat Commun, 14, 2023
2DC5
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BU of 2dc5 by Molmil
Crystal structure of mouse glutathione S-transferase, mu7 (GSTM7) at 1.6 A resolution
分子名称: Glutathione S-transferase, mu 7
著者Kamo, S, Kishishita, S, Murayama, K, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2005-12-28
公開日2006-06-28
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Crystal structure of mouse glutathione S-transferase, mu7 (GSTM7) at 1.6 A resolution
To be Published
2DD3
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An alternating sheared AA pair in 5'GGUGAAGGCU/3'PCCGAAGCCG: II. The minor conformation with A6/A5/A16 stack
分子名称: 5'-R(*GP*CP*CP*GP*AP*AP*GP*CP*CP*(P5P))-3', 5'-R(*GP*GP*UP*GP*AP*AP*GP*GP*CP*U)-3'
著者Chen, G, Kennedy, S.D, Krugh, T.R, Turner, D.H.
登録日2006-01-19
公開日2006-06-13
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献An Alternating Sheared AA Pair and Elements of Stability for a Single Sheared Purine-Purine Pair Flanked by Sheared GA Pairs in RNA
Biochemistry, 45, 2006
2DD2
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BU of 2dd2 by Molmil
An alternating sheared AA pair in 5'GGUGAAGGCU/3'PCCGAAGCCG: I. The major conformation with A6/A15/A16 stack
分子名称: 5'-R(*GP*CP*CP*GP*AP*AP*GP*CP*CP*(P5P))-3', 5'-R(*GP*GP*UP*GP*AP*AP*GP*GP*CP*U)-3'
著者Chen, G, Kennedy, S.D, Krugh, T.R, Turner, D.H.
登録日2006-01-19
公開日2006-06-13
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献An Alternating Sheared AA Pair and Elements of Stability for a Single Sheared Purine-Purine Pair Flanked by Sheared GA Pairs in RNA
Biochemistry, 45, 2006
2TAA
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BU of 2taa by Molmil
STRUCTURE AND POSSIBLE CATALYTIC RESIDUES OF TAKA-AMYLASE A
分子名称: CALCIUM ION, TAKA-AMYLASE A
著者Kusunoki, M, Matsuura, Y, Tanaka, N, Kakudo, M.
登録日1982-10-18
公開日1982-10-21
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structure and possible catalytic residues of Taka-amylase A
J.Biochem.(Tokyo), 95, 1984
2DM6
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BU of 2dm6 by Molmil
Crystal structure of anti-configuration of indomethacin and leukotriene B4 12-hydroxydehydrogenase/15-oxo-prostaglandin 13-reductase complex
分子名称: INDOMETHACIN, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, NADP-dependent leukotriene B4 12-hydroxydehydrogenase, ...
著者Hori, T, Ishijima, J, Yokomizo, T, Ago, H, Shimizu, T, Miyano, M, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2006-04-20
公開日2006-11-28
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structure of anti-configuration of indomethacin and leukotriene B4 12-hydroxydehydrogenase/15-oxo-prostaglandin 13-reductase complex reveals the structural basis of broad spectrum indomethacin efficacy
J.Biochem.(Tokyo), 140, 2006
2SIC
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BU of 2sic by Molmil
REFINED CRYSTAL STRUCTURE OF THE COMPLEX OF SUBTILISIN BPN' AND STREPTOMYCES SUBTILISIN INHIBITOR AT 1.8 ANGSTROMS RESOLUTION
分子名称: CALCIUM ION, STREPTOMYCES SUBTILISIN INHIBITOR (SSI), SUBTILISIN BPN'
著者Mitsui, Y, Takeuchi, Y, Hirono, S, Akagawa, H, Nakamura, K.T.
登録日1991-04-01
公開日1993-04-15
最終更新日2017-11-29
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Refined crystal structure of the complex of subtilisin BPN' and Streptomyces subtilisin inhibitor at 1.8 A resolution.
J.Mol.Biol., 221, 1991
2SNI
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BU of 2sni by Molmil
STRUCTURAL COMPARISON OF TWO SERINE PROTEINASE-PROTEIN INHIBITOR COMPLEXES. EGLIN-C-SUBTILISIN CARLSBERG AND CI-2-SUBTILISIN NOVO
分子名称: CALCIUM ION, CHYMOTRYPSIN INHIBITOR 2, SUBTILISIN NOVO
著者Mcphalen, C.A, James, M.N.G.
登録日1988-09-05
公開日1988-09-07
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural comparison of two serine proteinase-protein inhibitor complexes: eglin-c-subtilisin Carlsberg and CI-2-subtilisin Novo.
Biochemistry, 27, 1988
2SBT
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BU of 2sbt by Molmil
A COMPARISON OF THE THREE-DIMENSIONAL STRUCTURES OF SUBTILISIN BPN AND SUBTILISIN NOVO
分子名称: ACETONE, SUBTILISIN NOVO
著者Drenth, J, Hol, W.G.J, Jansonius, J.N, Koekoek, R.
登録日1976-09-07
公開日1976-10-06
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献A comparison of the three-dimensional structures of subtilisin BPN' and subtilisin novo.
Cold Spring Harbor Symp.Quant.Biol., 36, 1972
2ST1
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BU of 2st1 by Molmil
THE THREE-DIMENSIONAL STRUCTURE OF BACILLUS AMYLOLIQUEFACIENS SUBTILISIN AT 1.8 ANGSTROMS AND AN ANALYSIS OF THE STRUCTURAL CONSEQUENCES OF PEROXIDE INACTIVATION
分子名称: CALCIUM ION, SUBTILISIN BPN', SULFATE ION
著者Bott, R.
登録日1990-05-11
公開日1991-07-15
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献The three-dimensional structure of Bacillus amyloliquefaciens subtilisin at 1.8 A and an analysis of the structural consequences of peroxide inactivation.
J.Biol.Chem., 263, 1988
2UUY
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BU of 2uuy by Molmil
Structure of a tick tryptase inhibitor in complex with bovine trypsin
分子名称: CALCIUM ION, CATIONIC TRYPSIN, CHLORIDE ION, ...
著者Siebold, C, Paesen, G.C, Harlos, K, Peacey, M.F, Nuttall, P.A, Stuart, D.I.
登録日2007-03-08
公開日2007-04-10
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.15 Å)
主引用文献A Tick Protein with a Modified Kunitz Fold Inhibits Human Tryptase.
J.Mol.Biol., 368, 2007
2UZR
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BU of 2uzr by Molmil
A transforming mutation in the pleckstrin homology domain of AKT1 in cancer (AKT1-PH_E17K)
分子名称: RAC-alpha serine/threonine-protein kinase
著者Carpten, J.D, Faber, A.L, Horn, C, Donoho, G.P, Briggs, S.L, Robbins, C.M, Hostetter, G, Boguslawski, S, Moses, T.Y, Savage, S, Uhlik, M, Lin, A, Du, J, Qian, Y.W, Zeckner, D.J, Tucker-Kellogg, G, Touchman, J, Patel, K, Mousses, S, Bittner, M, Schevitz, R, Lai, M.H, Blanchard, K.L, Thomas, J.E.
登録日2007-05-01
公開日2007-07-17
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.94 Å)
主引用文献A transforming mutation in the pleckstrin homology domain of AKT1 in cancer.
Nature, 448, 2007
2ECR
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BU of 2ecr by Molmil
Crystal structure of the ligand-free form of the flavin reductase component (HpaC) of 4-hydroxyphenylacetate 3-monooxygenase
分子名称: flavin reductase component (HpaC) of 4-hydroxyphenylacetate 3-monooxygenase
著者Kim, S.H, Hisano, T, Iwasaki, W, Ebihara, A, Miki, K.
登録日2007-02-13
公開日2008-01-15
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Crystal structure of the flavin reductase component (HpaC) of 4-hydroxyphenylacetate 3-monooxygenase from Thermus thermophilus HB8: Structural basis for the flavin affinity
Proteins, 70, 2008
8A4J
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Human GDAP1, A247V mutant
分子名称: Ganglioside-induced differentiation-associated protein 1
著者Sutinen, A, Kursula, P.
登録日2022-06-12
公開日2023-04-26
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.68 Å)
主引用文献Conserved intramolecular networks in GDAP1 are closely connected to CMT-linked mutations and protein stability.
Plos One, 18, 2023
8A4K
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Human GDAP1, R282H mutant
分子名称: Ganglioside-induced differentiation-associated protein 1
著者Sutinen, A, Kursula, P.
登録日2022-06-12
公開日2023-04-26
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Conserved intramolecular networks in GDAP1 are closely connected to CMT-linked mutations and protein stability.
Plos One, 18, 2023

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