1XWQ
| Structure Of A Cold-Adapted Family 8 Xylanase | 分子名称: | beta-D-xylopyranose-(1-4)-beta-D-xylopyranose-(1-4)-beta-D-xylopyranose, endo-1,4-beta-xylanase | 著者 | De Vos, D, Collins, T, Hoyoux, A, Savvides, S.N, Gerday, C, Van Beeumen, J.J, Feller, G. | 登録日 | 2004-11-02 | 公開日 | 2005-10-11 | 最終更新日 | 2021-11-10 | 実験手法 | X-RAY DIFFRACTION (1.88 Å) | 主引用文献 | Study of the active site residues of a glycoside hydrolase family 8 xylanase J.Mol.Biol., 354, 2005
|
|
1XLM
| D254E, D256E MUTANT OF D-XYLOSE ISOMERASE COMPLEXED WITH AL3 AND XYLITOL | 分子名称: | ALUMINUM ION, D-XYLOSE ISOMERASE, Xylitol | 著者 | Gerczei, T, Bocskei, Z.S, Szabo, E, Naray-Szabo, G, Asboth, B. | 登録日 | 1997-07-22 | 公開日 | 1998-01-28 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Structure determination and refinement of the Al3+ complex of the D254,256E mutant of Arthrobacter D-xylose isomerase at 2.40 A resolution. Further evidence for inhibitor-induced metal ion movement. Int.J.Biol.Macromol., 25, 1999
|
|
3NHA
| Nucleotide Binding Domain of Human ABCB6 (ADP Mg bound structure) | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ATP-binding cassette sub-family B member 6, mitochondrial, ... | 著者 | Haffke, M, Menzel, A, Carius, Y, Jahn, D, Heinz, D.W. | 登録日 | 2010-06-14 | 公開日 | 2010-08-25 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structures of the nucleotide-binding domain of the human ABCB6 transporter and its complexes with nucleotides. Acta Crystallogr.,Sect.D, 66, 2010
|
|
1QWO
| Crystal structure of a phosphorylated phytase from Aspergillus fumigatus, revealing the structural basis for its heat resilience and catalytic pathway | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, phytase | 著者 | Xiang, T, Liu, Q, Deacon, A.M, Koshy, M, Kriksunov, I.A, Lei, X.G, Hao, Q, Thiel, D.J. | 登録日 | 2003-09-03 | 公開日 | 2004-06-01 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Crystal Structure of a Heat-resilient Phytase from Aspergillus fumigatus, Carrying a Phosphorylated Histidine J.Mol.Biol., 339, 2004
|
|
1SKV
| Crystal Structure of D-63 from Sulfolobus Spindle Virus 1 | 分子名称: | Hypothetical 7.5 kDa protein | 著者 | Kraft, P, Kummel, D, Oeckinghaus, A, Gauss, G.H, Wiedenheft, B, Young, M, Lawrence, C.M. | 登録日 | 2004-03-05 | 公開日 | 2004-07-13 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Structure of d-63 from sulfolobus spindle-shaped virus 1: surface properties of the dimeric four-helix bundle suggest an adaptor protein function J.Virol., 78, 2004
|
|
2EVD
| Crystal structure of human Glycolipid Transfer Protein complexed with 12:0 Lactosylceramide | 分子名称: | DECANE, Glycolipid transfer protein, LAURIC ACID, ... | 著者 | Malinina, L, Malakhova, M.L, Kanack, A.T, Abagyan, R, Brown, R.E, Patel, D.J. | 登録日 | 2005-10-31 | 公開日 | 2006-11-14 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | The liganding of glycolipid transfer protein is controlled by glycolipid acyl structure. Plos Biol., 4, 2006
|
|
1C7F
| D95E OXIDIZED FLAVODOXIN MUTANT FROM D. VULGARIS | 分子名称: | FLAVIN MONONUCLEOTIDE, FLAVODOXIN | 著者 | McCarthy, A, Walsh, M, Higgins, T, D'Arcy, D. | 登録日 | 2000-02-11 | 公開日 | 2000-08-23 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystallographic Investigation of the Role of Aspartate 95 in the Modulation of the Redox Potentials Of Desulfovibrio Vulgaris Flavodoxin Biochemistry, 41, 2002
|
|
2HRL
| Siglec-7 in complex with GT1b | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ETHYL-TRIMETHYL-SILANE, N-acetyl-alpha-neuraminic acid-(2-8)-N-acetyl-alpha-neuraminic acid-(2-3)-[2-acetamido-2-deoxy-beta-D-galactopyranose-(1-4)]beta-D-galactopyranose-(1-4)-beta-D-glucopyranose, ... | 著者 | Attrill, H, Imamura, A, Sharma, R.S, Kiso, M, Crocker, P.R, van Aalten, D.M.F. | 登録日 | 2006-07-20 | 公開日 | 2006-08-15 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Siglec-7 Undergoes a Major Conformational Change When Complexed with the {alpha}(2,8)-Disialylganglioside GT1b J.Biol.Chem., 281, 2006
|
|
3GEQ
| Structural basis for the chemical rescue of Src kinase activity | 分子名称: | 1-TERT-BUTYL-3-(4-CHLORO-PHENYL)-1H-PYRAZOLO[3,4-D]PYRIMIDIN-4-YLAMINE, Proto-oncogene tyrosine-protein kinase Src | 著者 | Muratore, K.E, Seeliger, M.A, Wang, Z, Fomina, D, Neiswinger, J, Havranek, J.J, Baker, D, Kuriyan, J, Cole, P.A. | 登録日 | 2009-02-25 | 公開日 | 2009-04-28 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Comparative analysis of mutant tyrosine kinase chemical rescue. Biochemistry, 48, 2009
|
|
1A43
| STRUCTURE OF THE HIV-1 CAPSID PROTEIN DIMERIZATION DOMAIN AT 2.6A RESOLUTION | 分子名称: | HIV-1 CAPSID | 著者 | Worthylake, D.K, Wang, H, Yoo, S, Sundquist, W.I, Hill, C.P. | 登録日 | 1998-02-10 | 公開日 | 1999-02-09 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Structures of the HIV-1 capsid protein dimerization domain at 2.6 A resolution. Acta Crystallogr.,Sect.D, 55, 1999
|
|
4H3G
| Structure of BACE Bound to 2-((7aR)-7a-(4-(3-cyanophenyl)thiophen-2-yl)-2-imino-3-methyl-4-oxohexahydro-1H-pyrrolo[3,4-d]pyrimidin-6(2H)-yl)nicotinonitrile | 分子名称: | 2-{(2E,4aR,7aR)-7a-[4-(3-cyanophenyl)thiophen-2-yl]-2-imino-3-methyl-4-oxooctahydro-6H-pyrrolo[3,4-d]pyrimidin-6-yl}pyridine-3-carbonitrile, Beta-secretase 1, L(+)-TARTARIC ACID | 著者 | Strickland, C, Mandal, M. | 登録日 | 2012-09-13 | 公開日 | 2012-11-07 | 最終更新日 | 2012-11-21 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Design and Validation of Bicyclic Iminopyrimidinones As Beta Amyloid Cleaving Enzyme-1 (BACE1) Inhibitors: Conformational Constraint to Favor a Bioactive Conformation. J.Med.Chem., 55, 2012
|
|
1NR2
| High resolution crystal structures of thymus and activation-regulated chemokine | 分子名称: | Thymus and activation-regulated chemokine | 著者 | Asojo, O.A, Boulegue, C, Hoover, D.M, Lu, W, Lubkowski, J. | 登録日 | 2003-01-23 | 公開日 | 2003-08-05 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.18 Å) | 主引用文献 | Structures of thymus and activation-regulated chemokine (TARC). Acta Crystallogr.,Sect.D, 59, 2003
|
|
183D
| X-RAY STRUCTURE OF A DNA DECAMER CONTAINING 7, 8-DIHYDRO-8-OXOGUANINE | 分子名称: | DNA (5'-D(*CP*CP*AP*(8OG)P*CP*GP*CP*TP*GP*G)-3') | 著者 | Lipscomb, L.A, Peek, M.E, Morningstar, M.L, Verghis, S.M, Miller, E.M, Rich, A, Essigmann, J.M, Williams, L.D. | 登録日 | 1994-08-01 | 公開日 | 1995-02-27 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | X-ray structure of a DNA decamer containing 7,8-dihydro-8-oxoguanine. Proc.Natl.Acad.Sci.USA, 92, 1995
|
|
1AMM
| 1.2 ANGSTROM STRUCTURE OF GAMMA-B CRYSTALLIN AT 150K | 分子名称: | GAMMA B-CRYSTALLIN | 著者 | Kumaraswamy, V.S, Lindley, P.F, Slingsby, C, Glover, I.D. | 登録日 | 1996-03-20 | 公開日 | 1996-11-08 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | 主引用文献 | An eye lens protein-water structure: 1.2 A resolution structure of gammaB-crystallin at 150 K. Acta Crystallogr.,Sect.D, 52, 1996
|
|
3GHC
| Design, Synthesis, and X-ray Crystal Structure of Classical and Nonclassical 2-amino-4-oxo-5-substituted-6-thieno[2,3-d]pyrimidines as dual thymidylate synthase and dihydrofolate reductase inhibitors and as potential antitumor agenst | 分子名称: | Dihydrofolate reductase, N-({4-[(2-amino-6-ethyl-4-oxo-3,4-dihydrothieno[2,3-d]pyrimidin-5-yl)sulfanyl]phenyl}carbonyl)-L-glutamic acid, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | 著者 | Cody, V. | 登録日 | 2009-03-03 | 公開日 | 2009-09-22 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | 主引用文献 | Design, synthesis, and X-ray crystal structure of classical and nonclassical 2-amino-4-oxo-5-substituted-6-ethylthieno[2,3-d]pyrimidines as dual thymidylate synthase and dihydrofolate reductase inhibitors and as potential antitumor agents J.Med.Chem., 52, 2009
|
|
1YQV
| The crystal structure of the antibody Fab HyHEL5 complex with lysozyme at 1.7A resolution | 分子名称: | Hen Egg White Lysozyme, HyHEL-5 Antibody Heavy Chain, HyHEL-5 Antibody Light Chain | 著者 | Cohen, G.H, Silverton, E.W, Padlan, E.A, Dyda, F, Wibbenmeyer, J.A, Wilson, R.C, Davies, D.R. | 登録日 | 2005-02-02 | 公開日 | 2005-04-26 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Water molecules in the antibody-antigen interface of the structure of the Fab HyHEL-5-lysozyme complex at 1.7 A resolution: comparison with results from isothermal titration calorimetry. Acta Crystallogr.,Sect.D, 61, 2005
|
|
3GAY
| Structure of Giardia fructose-1,6-biphosphate aldolase in complex with tagatose-1,6-biphosphate | 分子名称: | 1,6-di-O-phosphono-D-tagatose, Fructose-bisphosphate aldolase, ZINC ION | 著者 | Galkin, A, Herzberg, O. | 登録日 | 2009-02-18 | 公開日 | 2009-03-31 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structural insights into the substrate binding and stereoselectivity of giardia fructose-1,6-bisphosphate aldolase. Biochemistry, 48, 2009
|
|
463D
| CALCIUM FORM OF D(CGCGAATTCGCG)2 | 分子名称: | CALCIUM ION, DNA (5'-D(*CP*GP*CP*GP*AP*AP*TP*TP*CP*GP*CP*G)-3') | 著者 | Liu, J, Subirana, J.A. | 登録日 | 1999-03-29 | 公開日 | 1999-10-08 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | 主引用文献 | Structure of d(CGCGAATTCGCG) in the presence of Ca(2+) ions. J.Biol.Chem., 274, 1999
|
|
473D
| |
2CMF
| Torpedo californica acetylcholinesterase complexed with alkylene- linked bis-tacrine dimer (5 carbon linker) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETYLCHOLINESTERASE, N,N'-DI-1,2,3,4-TETRAHYDROACRIDIN-9-YLPENTANE-1,5-DIAMINE | 著者 | Rydberg, E.H, Brumshtein, B, Greenblatt, H.M, Wong, D.M, Pang, Y.P, Silman, I, Sussman, J.L. | 登録日 | 2006-05-08 | 公開日 | 2006-09-04 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Complexes of alkylene-linked tacrine dimers with Torpedo californica acetylcholinesterase: Binding of Bis5-tacrine produces a dramatic rearrangement in the active-site gorge. J. Med. Chem., 49, 2006
|
|
1C0K
| CRYSTAL STRUCTURE ANALYSIS OF D-AMINO ACID OXIDASE IN COMPLEX WITH L-LACTATE | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, LACTIC ACID, PROTEIN (D-AMINO ACID OXIDASE) | 著者 | Umhau, S, Molla, G, Diederichs, K, Pilone, M.S, Ghisla, S, Welte, W, Pollegioni, L. | 登録日 | 1999-07-16 | 公開日 | 2000-11-22 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.46 Å) | 主引用文献 | The x-ray structure of D-amino acid oxidase at very high resolution identifies the chemical mechanism of flavin-dependent substrate dehydrogenation. Proc.Natl.Acad.Sci.USA, 97, 2000
|
|
1BYJ
| GENTAMICIN C1A A-SITE COMPLEX | 分子名称: | 2,6-diamino-2,3,4,6-tetradeoxy-alpha-D-erythro-hexopyranose, 3,5-DIAMINO-CYCLOHEXANOL, 3-deoxy-4-C-methyl-3-(methylamino)-beta-L-arabinopyranose, ... | 著者 | Yoshizawa, S, Fourmy, D, Puglisi, J.D. | 登録日 | 1998-10-16 | 公開日 | 1999-10-29 | 最終更新日 | 2023-12-27 | 実験手法 | SOLUTION NMR | 主引用文献 | Structural origins of gentamicin antibiotic action. EMBO J., 17, 1998
|
|
4NJK
| Crystal Structure of QueE from Burkholderia multivorans in complex with AdoMet, 7-carboxy-7-deazaguanine, and Mg2+ | 分子名称: | 2-amino-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidine-5-carboxylic acid, 7-carboxy-7-deazaguanine synthase, IRON/SULFUR CLUSTER, ... | 著者 | Dowling, D.P, Bruender, N.A, Young, A.P, McCarty, R.M, Bandarian, V, Drennan, C.L. | 登録日 | 2013-11-10 | 公開日 | 2013-12-25 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.911 Å) | 主引用文献 | Radical SAM enzyme QueE defines a new minimal core fold and metal-dependent mechanism. Nat.Chem.Biol., 10, 2014
|
|
1W6J
| Structure of human OSC in complex with Ro 48-8071 | 分子名称: | LANOSTEROL SYNTHASE, TETRADECANE, [4-({6-[ALLYL(METHYL)AMINO]HEXYL}OXY)-2-FLUOROPHENYL](4-BROMOPHENYL)METHANONE, ... | 著者 | Thoma, R, Schulz-Gasch, T, D'Arcy, B, Benz, J, Aebi, J, Dehmlow, H, Hennig, M, Ruf, A. | 登録日 | 2004-08-18 | 公開日 | 2004-10-29 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Insight Into Steroid Scaffold Formation from the Structure of Human Oxidosqualene Cyclase Nature, 432, 2004
|
|
1LVS
| |