6Z19
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![BU of 6z19 by Molmil](/molmil-images/mine/6z19) | Crystal structure of P8C9 bound to CK2alpha | 分子名称: | ACETATE ION, ADENOSINE-5'-DIPHOSPHATE, Casein kinase II subunit alpha, ... | 著者 | Atkinson, E, Iegre, J, Brear, P, Baker, D, Sore, H, Hyvonen, M, Spring, D. | 登録日 | 2020-05-13 | 公開日 | 2021-05-26 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.47 Å) | 主引用文献 | Development of small cyclic peptides targeting the CK2 alpha / beta interface. Chem.Commun.(Camb.), 58, 2022
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2FNX
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![BU of 2fnx by Molmil](/molmil-images/mine/2fnx) | Design of Specific Peptide Inhibitors of Phospholipase A2 (PLA2): Crystal Structure of the Complex of PLA2 with a Highly Potent Peptide Val-Ile-Ala-Lys at 2.7A Resolution | 分子名称: | Inhibitor peptide, Phospholipase A2 VRV-PL-VIIIa, SULFATE ION | 著者 | Singh, N, Srivastava, P, Sharma, S, Dey, S, Singh, T.P. | 登録日 | 2006-01-11 | 公開日 | 2006-01-24 | 最終更新日 | 2018-01-24 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Design of Specific Peptide Inhibitors of Phospholipase A2 (PLA2): Crystal Structure of the Complex of PLA2 with a Highly Potent Peptide Val-Ile-Ala-Lys at 2.7A Resolution To be Published
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2G0N
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![BU of 2g0n by Molmil](/molmil-images/mine/2g0n) | The Crystal Structure of the Human RAC3 in complex with GDP and Chloride | 分子名称: | CHLORIDE ION, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | 著者 | Ugochukwu, E, Yang, X, Zao, Y, Elkins, J, Gileadi, C, Burgess, N, Colebrook, S, Gileadi, O, Fedorov, O, Bunkoczi, G, Sundstrom, M, Arrowsmith, C, Weigelt, J, Edwards, A, von Delft, F, Doyle, D, Structural Genomics Consortium (SGC) | 登録日 | 2006-02-13 | 公開日 | 2006-05-30 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | The Crystal Structure of the Human RAC3 in complex with GDP and Chloride To be Published
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2G11
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![BU of 2g11 by Molmil](/molmil-images/mine/2g11) | Photolyzed CO L29F Myoglobin: 31.6ns | 分子名称: | CARBON MONOXIDE, Myoglobin, PROTOPORPHYRIN IX CONTAINING FE, ... | 著者 | Aranda, R, Levin, E.J, Schotte, F, Anfinrud, P.A, Phillips Jr, G.N. | 登録日 | 2006-02-13 | 公開日 | 2006-07-04 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Time-dependent atomic coordinates for the dissociation of carbon monoxide from myoglobin. ACTA CRYSTALLOGR.,SECT.D, 62, 2006
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2FO9
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![BU of 2fo9 by Molmil](/molmil-images/mine/2fo9) | Structure of porcine pancreatic elastase in 95% acetone | 分子名称: | ACETONE, CALCIUM ION, SULFATE ION, ... | 著者 | Mattos, C, Bellamacina, C.R, Peisach, E, Pereira, A, Vitkup, D, Petsko, G.A, Ringe, D. | 登録日 | 2006-01-13 | 公開日 | 2006-04-18 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Multiple solvent crystal structures: Probing binding sites, plasticity and hydration J.Mol.Biol., 357, 2006
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2FOH
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![BU of 2foh by Molmil](/molmil-images/mine/2foh) | Structure of porcine pancreatic elastase in 40% trifluoroethanol | 分子名称: | CALCIUM ION, SULFATE ION, TRIFLUOROETHANOL, ... | 著者 | Mattos, C, Bellamacina, C.R, Peisach, E, Pereira, A, Vitkup, D, Petsko, G.A, Ringe, D. | 登録日 | 2006-01-13 | 公開日 | 2006-04-18 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Multiple solvent crystal structures: Probing binding sites, plasticity and hydration J.Mol.Biol., 357, 2006
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2G1R
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![BU of 2g1r by Molmil](/molmil-images/mine/2g1r) | Ketopiperazine-Based Renin Inhibitors: Optimization of the C Ring | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, N-{2-[6-(2,4-DIAMINO-6-ETHYLPYRIMIDIN-5-YL)-2,2-DIMETHYL-3-OXO-2,3-DIHYDRO-4H-1,4-BENZOXAZIN-4-YL]ETHYL}ACETAMIDE, Renin | 著者 | Holsworth, D.D, Jalaiea, M, Zhanga, E, Mcconnella, P. | 登録日 | 2006-02-14 | 公開日 | 2006-06-13 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.42 Å) | 主引用文献 | Ketopiperazine-Based Renin Inhibitors: Optimization of the "C" Ring BIOORG.MED.CHEM.LETT., 16, 2006
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4KB8
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2G3H
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![BU of 2g3h by Molmil](/molmil-images/mine/2g3h) | Cyanide Binding and Heme Cavity Conformational Transitions in Drosophila melanogaster Hexa-coordinate Hemoglobin | 分子名称: | CHLORIDE ION, CYANIDE ION, MAGNESIUM ION, ... | 著者 | de Sanctis, D, Ascenzi, P, Bocedi, A, Dewilde, S, Burmester, T, Hankeln, T, Moens, L, Bolognesi, M. | 登録日 | 2006-02-20 | 公開日 | 2006-10-03 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Cyanide binding and heme cavity conformational transitions in Drosophila melanogaster hexacoordinate hemoglobin. Biochemistry, 45, 2006
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2M7P
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![BU of 2m7p by Molmil](/molmil-images/mine/2m7p) | RXFP1 utilises hydrophobic moieties on a signalling surface of the LDLa module to mediate receptor activation | 分子名称: | CALCIUM ION, Low-density lipoprotein receptor, Relaxin receptor 1 | 著者 | Kong, R.CK, Petrie, E.J, Mohanty, B, Ling, J, Lee, J.C.Y, Gooley, P.R, Bathgate, R.A.D. | 登録日 | 2013-04-29 | 公開日 | 2013-08-14 | 最終更新日 | 2023-06-14 | 実験手法 | SOLUTION NMR | 主引用文献 | The relaxin receptor (RXFP1) utilizes hydrophobic moieties on a signaling surface of its N-terminal low density lipoprotein class A module to mediate receptor activation. J.Biol.Chem., 288, 2013
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4KS7
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2G4V
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![BU of 2g4v by Molmil](/molmil-images/mine/2g4v) | anomalous substructure of proteinase K | 分子名称: | CALCIUM ION, CHLORIDE ION, POTASSIUM ION, ... | 著者 | Mueller-Dieckmann, C, Weiss, M.S. | 登録日 | 2006-02-22 | 公開日 | 2007-02-20 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.14 Å) | 主引用文献 | On the routine use of soft X-rays in macromolecular crystallography. Part IV. Efficient determination of anomalous substructures in biomacromolecules using longer X-ray wavelengths. Acta Crystallogr.,Sect.D, 63, 2007
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2FYJ
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![BU of 2fyj by Molmil](/molmil-images/mine/2fyj) | NMR Solution structure of calcium-loaded LRP double module | 分子名称: | Low-density lipoprotein receptor-related protein 1 | 著者 | Jensen, G.A, Andersen, O.M, Bonvin, A.M, Bjerrum-Bohr, I, Etzerodt, M, O'shea, C, Poulsen, F.M, Kragelund, B.B. | 登録日 | 2006-02-08 | 公開日 | 2006-10-10 | 最終更新日 | 2022-03-09 | 実験手法 | SOLUTION NMR | 主引用文献 | Binding Site Structure of One LRP-RAP Complex:Implications for a Common Ligand-Receptor Binding Motif. J.Mol.Biol., 362, 2006
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2G94
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![BU of 2g94 by Molmil](/molmil-images/mine/2g94) | Crystal structure of beta-secretase bound to a potent and highly selective inhibitor. | 分子名称: | Beta-secretase 1, N~2~-[(2R,4S,5S)-5-{[N-{[(3,5-DIMETHYL-1H-PYRAZOL-1-YL)METHOXY]CARBONYL}-3-(METHYLSULFONYL)-L-ALANYL]AMINO}-4-HYDROXY-2,7-DIMETHYLOCTANOYL]-N-ISOBUTYL-L-VALINAMIDE | 著者 | Hong, L, Ghosh, A, Tang, J. | 登録日 | 2006-03-05 | 公開日 | 2006-04-25 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.86 Å) | 主引用文献 | Design, synthesis and X-ray structure of protein-ligand complexes: important insight into selectivity of memapsin 2 (beta-secretase) inhibitors. J.Am.Chem.Soc., 128, 2006
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2FOG
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![BU of 2fog by Molmil](/molmil-images/mine/2fog) | Structure of porcine pancreatic elastase in 40% trifluoroethanol | 分子名称: | CALCIUM ION, SULFATE ION, TRIFLUOROETHANOL, ... | 著者 | Mattos, C, Bellamacina, C.R, Peisach, E, Pereira, A, Vitkup, D, Petsko, G.A, Ringe, D. | 登録日 | 2006-01-13 | 公開日 | 2006-04-18 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Multiple solvent crystal structures: Probing binding sites, plasticity and hydration J.Mol.Biol., 357, 2006
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2FS6
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2FV8
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![BU of 2fv8 by Molmil](/molmil-images/mine/2fv8) | The crystal structure of RhoB in the GDP-bound state | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, Rho-related GTP-binding protein RhoB | 著者 | Turnbull, A.P, Soundararajan, M, Smee, C, Johansson, C, Schoch, G, Gorrec, F, Bray, J, Papagrigoriou, E, von Delft, F, Weigelt, J, Edwards, A, Arrowsmith, C, Sundstrom, M, Doyle, D, Structural Genomics Consortium (SGC) | 登録日 | 2006-01-30 | 公開日 | 2006-02-28 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | The crystal structure of RhoB in the GDP-bound state To be Published
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2MC1
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![BU of 2mc1 by Molmil](/molmil-images/mine/2mc1) | Solution structure of the Vav1 SH2 domain complexed with a Syk-derived singly phosphorylated peptide | 分子名称: | Proto-oncogene vav, Tyrosine-protein kinase SYK | 著者 | Chen, C, Piraner, D, Gorenstein, N.M, Geahlen, R.L, Post, C.B. | 登録日 | 2013-08-13 | 公開日 | 2013-08-28 | 最終更新日 | 2023-06-14 | 実験手法 | SOLUTION NMR | 主引用文献 | Differential recognition of syk-binding sites by each of the two phosphotyrosine-binding pockets of the Vav SH2 domain. Biopolymers, 99, 2013
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2FVQ
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![BU of 2fvq by Molmil](/molmil-images/mine/2fvq) | A Structural Study of the CA Dinucleotide Step in the Integrase Processing Site of Moloney Murine Leukemia Virus | 分子名称: | 5'-D(*CP*TP*TP*TP*CP*AP*TP*TP*AP*AP*TP*GP*AP*AP*AP*G)-3', reverse transcriptase | 著者 | Montano, S.P, Cote, M.L, Roth, M.J, Georgiadis, M.M. | 登録日 | 2006-01-31 | 公開日 | 2006-12-12 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Crystal structures of oligonucleotides including the integrase processing site of the Moloney murine leukemia virus. Nucleic Acids Res., 34, 2006
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2MCZ
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![BU of 2mcz by Molmil](/molmil-images/mine/2mcz) | CR1 Sushi domains 1 and 2 | 分子名称: | Complement receptor type 1 | 著者 | Park, H.J, Guariento, M.J, Maciejewski, M, Hauart, R, Tham, W, Cowman, A.F, Schmidt, C.Q, Martens, H, Liszewski, K.M, Hourcade, D, Barlow, P.N, Atkinson, J.P. | 登録日 | 2013-08-27 | 公開日 | 2013-11-13 | 最終更新日 | 2023-06-14 | 実験手法 | SOLUTION NMR | 主引用文献 | Using Mutagenesis and Structural Biology to Map the Binding Site for the Plasmodium falciparum Merozoite Protein PfRh4 on the Human Immune Adherence Receptor. J.Biol.Chem., 289, 2014
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4IDV
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![BU of 4idv by Molmil](/molmil-images/mine/4idv) | Crystal Structure of NIK with compound 4-{3-[2-amino-5-(2-methoxyethoxy)pyrimidin-4-yl]-1H-indol-5-yl}-2-methylbut-3-yn-2-ol (13V) | 分子名称: | 4-{3-[2-amino-5-(2-methoxyethoxy)pyrimidin-4-yl]-1H-indol-5-yl}-2-methylbut-3-yn-2-ol, Mitogen-activated protein kinase kinase kinase 14 | 著者 | Liu, J, Sudom, A, Wang, Z. | 登録日 | 2012-12-13 | 公開日 | 2013-04-17 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Inhibiting NF-KB-inducing kinase (NIK): Discovery, structure-based design, synthesis, structure activity relationship, and co-crystal structures Bioorg.Med.Chem.Lett., 23, 2013
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2FX6
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2LY9
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![BU of 2ly9 by Molmil](/molmil-images/mine/2ly9) | Solution NMR Structure of Homeobox 2 Domain from Human ZHX1 repressor, Northeast Structural Genomics Consortium (NESG) Target HR7907F | 分子名称: | Zinc fingers and homeoboxes protein 1 | 著者 | Xu, X, Eletsky, A, Mills, J.L, Pulavarti, S.V.S.R.K, Lee, D, Kohan, E, Janjua, H, Xiao, R, Acton, T.B, Everett, J.K, Montelione, G.T, Szyperski, T, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2012-09-14 | 公開日 | 2012-11-14 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution NMR Structure of Homeobox 2 Domain from Human ZHX1 repressor, Northeast Structural Genomics Consortium (NESG) Target HR7907F To be Published
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2LXI
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4IJ9
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![BU of 4ij9 by Molmil](/molmil-images/mine/4ij9) | Bovine PKA C-alpha in complex with 2-[[5-(4-pyridyl)-1H-1,2,4-triazol-3-yl]sulfanyl]-1-(2-thiophenyl)ethanone | 分子名称: | 2-[[5-(4-pyridyl)-1H-1,2,4-triazol-3-yl]sulfanyl]-1-(2-thiophenyl)ethanone, cAMP-dependent protein kinase catalytic subunit alpha, cAMP-dependent protein kinase inhibitor alpha | 著者 | Dreyer, M.K, Schiffer, A. | 登録日 | 2012-12-21 | 公開日 | 2013-05-01 | 最終更新日 | 2017-11-15 | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | 主引用文献 | Accounting for Conformational Variability in Protein-Ligand Docking with NMR-Guided Rescoring J.Am.Chem.Soc., 135, 2013
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