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6LDI
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The cryo-EM structure of E. coli CueR transcription activation complex
分子名称: DNA (50-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
著者Fang, C.L, Zhang, Y.
登録日2019-11-21
公開日2020-09-30
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (3.69 Å)
主引用文献CueR activates transcription through a DNA distortion mechanism.
Nat.Chem.Biol., 17, 2021
8Y0X
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BU of 8y0x by Molmil
Dormant ribosome with SERBP1
分子名称: 18S rRNA, 28S rRNA, 40S ribosomal protein S10, ...
著者Du, M, Zeng, F.
登録日2024-01-23
公開日2024-02-07
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献The global structure of dormant ribosome
To Be Published
8Y0W
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BU of 8y0w by Molmil
dormant ribosome with eIF5A, eEF2 and SERBP1
分子名称: 18S rRNA, 28S rRNA, 40S ribosomal protein S10, ...
著者Du, M, Zeng, F.
登録日2024-01-23
公開日2024-02-07
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献dormant ribosome with eIF5A, eEF2 and SERBP1
To Be Published
8XXL
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BU of 8xxl by Molmil
Cryo-EM structure of the human 40S ribosome with PDCD4
分子名称: 18S rRNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ...
著者Ye, X, Huang, Z, Li, Y, Wang, M, Cheng, J.
登録日2024-01-18
公開日2024-05-01
最終更新日2024-07-10
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Human tumor suppressor PDCD4 directly interacts with ribosomes to repress translation.
Cell Res., 34, 2024
8XXM
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BU of 8xxm by Molmil
Cryo-EM structure of the human 40S ribosome with PDCD4 and eIF3G
分子名称: 18S rRNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ...
著者Ye, X, Huang, Z, Li, Y, Wang, M, Cheng, J.
登録日2024-01-18
公開日2024-05-01
最終更新日2024-07-10
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Human tumor suppressor PDCD4 directly interacts with ribosomes to repress translation.
Cell Res., 34, 2024
8XXN
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BU of 8xxn by Molmil
Cryo-EM structure of the human 43S ribosome with PDCD4
分子名称: 18S rRNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ...
著者Ye, X, Huang, Z, Li, Y, Wang, M, Cheng, J.
登録日2024-01-18
公開日2024-05-01
最終更新日2024-07-10
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Human tumor suppressor PDCD4 directly interacts with ribosomes to repress translation.
Cell Res., 34, 2024
4RB3
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BU of 4rb3 by Molmil
Crystal structure of Magnetospirillum gryphiswaldense MSR-1 Fur-Mn2+-feoAB1 operator
分子名称: DNA (25-MER), DNA-binding transcriptional dual regulator of siderophore biosynthesis and transport(Fur family), MANGANESE (II) ION, ...
著者Deng, Z, Chen, Z.
登録日2014-09-12
公開日2015-07-15
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Mechanistic insights into metal ion activation and operator recognition by the ferric uptake regulator.
Nat Commun, 6
4RB2
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Crystal structure of Magnetospirillum gryphiswaldense MSR-1 SeMet-Fur-Mn2+-feoAB1 operator
分子名称: DNA (25-MER), DNA-binding transcriptional dual regulator of siderophore biosynthesis and transport(Fur family), MANGANESE (II) ION
著者Deng, Z, Chen, Z.
登録日2014-09-12
公開日2015-07-15
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (2.82 Å)
主引用文献Mechanistic insights into metal ion activation and operator recognition by the ferric uptake regulator.
Nat Commun, 6
4RB1
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Crystal structure of Magnetospirillum gryphiswaldense MSR-1 Fur-Mn2+-E. coli Fur box
分子名称: DNA (5'-D(*CP*GP*CP*GP*AP*TP*AP*AP*TP*GP*AP*TP*AP*AP*TP*CP*AP*TP*TP*AP*TP*CP*CP*GP*C)-3'), DNA-binding transcriptional dual regulator of siderophore biosynthesis and transport(Fur family), MANGANESE (II) ION
著者Deng, Z, Chen, Z.
登録日2014-09-12
公開日2015-07-15
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Mechanistic insights into metal ion activation and operator recognition by the ferric uptake regulator.
Nat Commun, 6
8C03
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Structure of SLC40/ferroportin in complex with vamifeport and synthetic nanobody Sy12 in outward-facing conformation
分子名称: 2-[2-[2-(1~{H}-benzimidazol-2-yl)ethylamino]ethyl]-~{N}-[(3-fluoranylpyridin-2-yl)methyl]-1,3-oxazole-4-carboxamide, Solute carrier family 40 member 1
著者Lehmann, E.F, Liziczai, M, Drozdzyk, K, Dutzler, R, Manatschal, C.
登録日2022-12-15
公開日2023-03-22
最終更新日2024-07-24
実験手法ELECTRON MICROSCOPY (3.89 Å)
主引用文献Structures of ferroportin in complex with its specific inhibitor vamifeport.
Elife, 12, 2023
8BZY
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BU of 8bzy by Molmil
Structure of SLC40/ferroportin in complex with vamifeport and synthetic nanobody Sy3 in occluded conformation
分子名称: 2-[2-[2-(1~{H}-benzimidazol-2-yl)ethylamino]ethyl]-~{N}-[(3-fluoranylpyridin-2-yl)methyl]-1,3-oxazole-4-carboxamide, DIUNDECYL PHOSPHATIDYL CHOLINE, Solute carrier family 40 member 1, ...
著者Lehmann, E.F, Liziczai, M, Drozdzyk, K, Dutzler, R, Manatschal, C.
登録日2022-12-15
公開日2023-03-22
最終更新日2023-05-24
実験手法ELECTRON MICROSCOPY (3.24 Å)
主引用文献Structures of ferroportin in complex with its specific inhibitor vamifeport.
Elife, 12, 2023
8C02
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Structure of SLC40/ferroportin in complex with synthetic nanobody Sy3 in occluded conformation
分子名称: Solute carrier family 40 member 1, Sybody3
著者Lehmann, E.F, Liziczai, M, Drozdzyk, K, Dutzler, R, Manatschal, C.
登録日2022-12-15
公開日2023-03-22
最終更新日2023-03-29
実験手法ELECTRON MICROSCOPY (4.09 Å)
主引用文献Structures of ferroportin in complex with its specific inhibitor vamifeport.
Elife, 12, 2023
3KRQ
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BU of 3krq by Molmil
Crystal structure of the complex of lactoperoxidase with a potent inhibitor amino-triazole at 2.2a resolution
分子名称: (4R)-2-METHYLPENTANE-2,4-DIOL, 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 3-AMINO-1,2,4-TRIAZOLE, ...
著者Singh, A.K, Singh, N, Sinha, M, Kushwaha, G.S, Kaur, P, Srinivasan, A, Sharma, S, Singh, T.P.
登録日2009-11-19
公開日2010-05-26
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献First structural evidence for the mode of diffusion of aromatic ligands and ligand-induced closure of the hydrophobic channel in heme peroxidases
J.Biol.Inorg.Chem., 15, 2010
7C17
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BU of 7c17 by Molmil
The cryo-EM structure of E. coli CueR transcription activation complex with fully duplex promoter DNA
分子名称: DNA (72-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
著者Fang, C.L, Zhang, Y.
登録日2020-05-02
公開日2020-09-30
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (4.22 Å)
主引用文献CueR activates transcription through a DNA distortion mechanism.
Nat.Chem.Biol., 17, 2021
6PB6
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BU of 6pb6 by Molmil
The E. coli class-II CAP-dependent transcription activation complex at the state 2
分子名称: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
著者Liu, B, Shi, W.
登録日2019-06-13
公開日2020-03-18
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (4.29 Å)
主引用文献Visualization of two architectures in class-II CAP-dependent transcription activation
Plos Biol., 18, 2020
5U8K
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RitR mutant - C128S
分子名称: Response regulator
著者Silvaggi, N.R, Han, L.
登録日2016-12-14
公開日2017-12-20
最終更新日2018-11-28
実験手法X-RAY DIFFRACTION (1.69 Å)
主引用文献RitR is an archetype for a novel family of redox sensors in the streptococci that has evolved from two-component response regulators and is required for pneumococcal colonization.
PLoS Pathog., 14, 2018
5U8M
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A novel family of redox sensors in the streptococci evolved from two-component response regulators
分子名称: Response regulator
著者Han, L, Silvaggi, N.R.
登録日2016-12-14
公開日2017-12-20
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.105 Å)
主引用文献RitR is an archetype for a novel family of redox sensors in the streptococci that has evolved from two-component response regulators and is required for pneumococcal colonization.
PLoS Pathog., 14, 2018
6ZTP
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BU of 6ztp by Molmil
E. coli 70S-RNAP expressome complex in uncoupled state 6
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Webster, M.W, Takacs, M, Weixlbaumer, A.
登録日2020-07-20
公開日2020-09-16
最終更新日2024-04-24
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Structural basis of transcription-translation coupling and collision in bacteria.
Science, 369, 2020
6ZTJ
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BU of 6ztj by Molmil
E. coli 70S-RNAP expressome complex in NusG-coupled state (38 nt intervening mRNA)
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S1, ...
著者Webster, M.W, Takacs, M, Weixlbaumer, A.
登録日2020-07-20
公開日2020-09-16
最終更新日2024-04-24
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Structural basis of transcription-translation coupling and collision in bacteria.
Science, 369, 2020
6ZTO
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BU of 6zto by Molmil
E. coli 70S-RNAP expressome complex in uncoupled state 1
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Webster, M.W, Takacs, M, Weixlbaumer, A.
登録日2020-07-20
公開日2020-09-23
最終更新日2024-04-24
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Structural basis of transcription-translation coupling and collision in bacteria.
Science, 369, 2020
6ZTN
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BU of 6ztn by Molmil
E. coli 70S-RNAP expressome complex in NusG-coupled state (42 nt intervening mRNA)
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Webster, M.W, Takacs, M, Weixlbaumer, A.
登録日2020-07-20
公開日2020-09-16
最終更新日2024-04-24
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Structural basis of transcription-translation coupling and collision in bacteria.
Science, 369, 2020
6ZU1
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BU of 6zu1 by Molmil
E. coli 70S-RNAP expressome complex in uncoupled state 2
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Webster, M.W, Takacs, M, Weixlbaumer, A.
登録日2020-07-21
公開日2020-09-16
最終更新日2024-04-24
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Structural basis of transcription-translation coupling and collision in bacteria.
Science, 369, 2020
6ZTL
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BU of 6ztl by Molmil
E. coli 70S-RNAP expressome complex in collided state bound to NusG
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Webster, M.W, Takacs, M, Weixlbaumer, A.
登録日2020-07-20
公開日2020-09-16
最終更新日2024-04-24
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Structural basis of transcription-translation coupling and collision in bacteria.
Science, 369, 2020
6O0N
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M.tb MenD with Inhibitor
分子名称: 1,4-dihydroxy-2-naphthoic acid, 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase
著者Johnston, J.M, Ho, N.A.T, Bashiri, G, Bulloch, E.M, Nigon, L.V, Jirgis, E.M.N, Baker, E.N.
登録日2019-02-16
公開日2020-02-19
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.03 Å)
主引用文献Allosteric regulation of menaquinone (vitamin K2) biosynthesis in the human pathogenMycobacterium tuberculosis.
J.Biol.Chem., 295, 2020
8AD1
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RNA polymerase at U-rich pause bound to RNA putL triple mutant - pause prone, closed clamp state
分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
著者Dey, S, Weixlbaumer, A.
登録日2022-07-07
公開日2022-10-19
最終更新日2024-07-24
実験手法ELECTRON MICROSCOPY (4.1 Å)
主引用文献Structural insights into RNA-mediated transcription regulation in bacteria.
Mol.Cell, 82, 2022

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件を2024-08-07に公開中

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