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6MTO
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BU of 6mto by Molmil
Crystal structure of VRC42.01 Fab in complex with T117-F MPER scaffold
分子名称: Antibody VRC42.01 Fab heavy chain, Antibody VRC42.01 Fab light chain, VRC42 epitope T117-F scaffold
著者Kwon, Y.D, Druz, A, Law, W.H, Peng, D, Zhang, B, Doria-Rose, N.A, Kwong, P.D.
登録日2018-10-21
公開日2019-03-27
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.634 Å)
主引用文献Longitudinal Analysis Reveals Early Development of Three MPER-Directed Neutralizing Antibody Lineages from an HIV-1-Infected Individual.
Immunity, 50, 2019
6MTR
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BU of 6mtr by Molmil
Crystal structure of VRC43.01 Fab
分子名称: Antibody VRC43.01 Fab heavy chain, Antibody VRC43.01 Fab light chain
著者Kwon, Y.D, Druz, A, Law, W.H, Peng, D, Zhang, B, Doria-Rose, N.A, Kwong, P.D.
登録日2018-10-21
公開日2019-03-27
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.798 Å)
主引用文献Longitudinal Analysis Reveals Early Development of Three MPER-Directed Neutralizing Antibody Lineages from an HIV-1-Infected Individual.
Immunity, 50, 2019
6MTS
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BU of 6mts by Molmil
Crystal structure of VRC43.03 Fab
分子名称: Antibody VRC43.03 Fab heavy chain, Antibody VRC43.03 Fab light chain
著者Kwon, Y.D, Druz, A, Law, W.H, Peng, D, Doria-Rose, N.A, Kwong, P.D.
登録日2018-10-21
公開日2019-03-27
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.437 Å)
主引用文献Longitudinal Analysis Reveals Early Development of Three MPER-Directed Neutralizing Antibody Lineages from an HIV-1-Infected Individual.
Immunity, 50, 2019
6MTP
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BU of 6mtp by Molmil
Crystal structure of VRC42.04 Fab in complex with gp41 peptide
分子名称: Antibody VRC42.04 Fab heavy chain, Antibody VRC42.04 Fab light chain, RV217 founder virus gp41 peptide
著者Kwon, Y.D, Druz, A, Law, W.H, Peng, D, Zhang, B, Doria-Rose, N.A, Kwong, P.D.
登録日2018-10-21
公開日2019-03-27
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.036 Å)
主引用文献Longitudinal Analysis Reveals Early Development of Three MPER-Directed Neutralizing Antibody Lineages from an HIV-1-Infected Individual.
Immunity, 50, 2019
6MTT
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BU of 6mtt by Molmil
Crystal structure of VRC46.01 Fab in complex with gp41 peptide
分子名称: Antibody VRC46.01 Fab heavy chain, Antibody VRC46.01 Fb light chain, RV217 founder virus gp41 peptide
著者Kwon, Y.D, Druz, A, Law, W.H, Peng, D, Veradi, R, Doria-Rose, N.A, Kwong, P.D.
登録日2018-10-21
公開日2019-03-27
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Longitudinal Analysis Reveals Early Development of Three MPER-Directed Neutralizing Antibody Lineages from an HIV-1-Infected Individual.
Immunity, 50, 2019
6MTQ
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BU of 6mtq by Molmil
Crystal structure of VRC42.N1 Fab in complex with T117-F MPER scaffold
分子名称: Antibody VRC42.N1 Fab heavy chain, Antibody VRC42.N1 Fab light chain, VRC42 epitope T117-F scaffold
著者Kwon, Y.D, Law, W.H, Veradi, R, Doria-Rose, N.A, Kwong, P.D.
登録日2018-10-21
公開日2019-03-27
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Longitudinal Analysis Reveals Early Development of Three MPER-Directed Neutralizing Antibody Lineages from an HIV-1-Infected Individual.
Immunity, 50, 2019
6U8C
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BU of 6u8c by Molmil
Crystal structure of an engineered ultra-high affinity Fab-Protein G complex
分子名称: Antibody heavy chain Fab, Antibody light chain Fab, Protein G
著者Slezak, T, Filippova, E.V, Davydova, E.K, Kossiakoff, A.A.
登録日2019-09-04
公開日2019-10-23
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.61 Å)
主引用文献An engineered ultra-high affinity Fab-Protein G pair enables a modular antibody platform with multifunctional capability.
Protein Sci., 29, 2020
8TMA
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BU of 8tma by Molmil
Antibody N3-1 bound to RBD in the up conformation
分子名称: N3-1 Fab heavy chain, N3-1 Fab light chain, Spike glycoprotein
著者Hsieh, C.-L, McLellan, J.S.
登録日2023-07-29
公開日2024-01-17
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献SARS-COV-2 Omicron variants conformationally escape a rare quaternary antibody binding mode.
Commun Biol, 6, 2023
8TM1
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BU of 8tm1 by Molmil
Antibody N3-1 bound to RBDs in the up and down conformations
分子名称: N3-1 Fab heavy chain, N3-1 Fab light chain, Spike glycoprotein
著者Hsieh, C.-L, McLellan, J.S.
登録日2023-07-27
公開日2024-01-17
実験手法ELECTRON MICROSCOPY (2.79 Å)
主引用文献SARS-COV-2 Omicron variants conformationally escape a rare quaternary antibody binding mode.
Commun Biol, 6, 2023
5W5L
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BU of 5w5l by Molmil
Crystal structure of human IgG1-Sigma Fc fragment
分子名称: Immunoglobulin gamma-1 heavy chain, beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose
著者Armstrong, A.A, Gilliland, G.L.
登録日2017-06-15
公開日2017-09-13
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Functional, Biophysical, and Structural Characterization of Human IgG1 and IgG4 Fc Variants with Ablated Immune Functionality.
Antibodies, 6, 2017
5W5M
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BU of 5w5m by Molmil
Crystal structure of human IgG4-Sigma1 Fc fragment
分子名称: ACETATE ION, GLYCEROL, Immunoglobulin heavy constant gamma 4, ...
著者Armstrong, A.A, Gilliland, G.L.
登録日2017-06-15
公開日2017-09-13
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Functional, Biophysical, and Structural Characterization of Human IgG1 and IgG4 Fc Variants with Ablated Immune Functionality.
Antibodies, 6, 2017
5W5N
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BU of 5w5n by Molmil
Crystal structure of human IgG4-Sigma2 Fc fragment
分子名称: ACETATE ION, GLYCEROL, Immunoglobulin heavy constant gamma 4, ...
著者Armstrong, A.A, Gilliland, G.L.
登録日2017-06-15
公開日2017-09-13
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Functional, Biophysical, and Structural Characterization of Human IgG1 and IgG4 Fc Variants with Ablated Immune Functionality.
Antibodies, 6, 2017
7R8N
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BU of 7r8n by Molmil
Structure of the SARS-CoV-2 S 6P trimer in complex with neutralizing antibody C051
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, C051 Fab Heavy Chain, ...
著者Barnes, C.O, Bjorkman, P.J.
登録日2021-06-26
公開日2021-08-04
最終更新日2021-10-06
実験手法ELECTRON MICROSCOPY (3.55 Å)
主引用文献Affinity maturation of SARS-CoV-2 neutralizing antibodies confers potency, breadth, and resilience to viral escape mutations.
Immunity, 54, 2021
7R8L
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BU of 7r8l by Molmil
Structure of the SARS-CoV-2 RBD in complex with neutralizing antibody C099 and CR3022
分子名称: C099 Fab Heavy Chain, C099 Fab Light Chain, CR3022 Fab heavy chain, ...
著者Barnes, C.O, Bjorkman, P.J.
登録日2021-06-26
公開日2021-08-04
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Affinity maturation of SARS-CoV-2 neutralizing antibodies confers potency, breadth, and resilience to viral escape mutations.
Immunity, 54, 2021
8BE1
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BU of 8be1 by Molmil
SARS-CoV-2 RBD in complex with a Fab fragment of a neutralising antibody mRBD2
分子名称: Antibody heavy chain, Antibody light chain, SULFATE ION, ...
著者Lulla, A, Brear, P, Fischer, K, Hollfelder, F, Hyvonen, M.
登録日2022-10-21
公開日2023-01-25
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.98 Å)
主引用文献Microfluidics-enabled fluorescence-activated cell sorting of single pathogen-specific antibody secreting cells for the rapid discovery of monoclonal antibodies
Biorxiv, 2023
1U8K
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BU of 1u8k by Molmil
Crystal structure of the HIV-1 Cross Neutralizing Monoclonal Antibody 2F5 in complex with gp41 Peptide LELDKWASL
分子名称: ANTIBODY 2F5 (HEAVY CHAIN), ANTIBODY 2F5 (LIGHT CHAIN), GP41 PEPTIDE
著者Bryson, S, Julien, J.-P, Pai, E.F.
登録日2004-08-06
公開日2004-10-05
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.24 Å)
主引用文献Crystal structure of the HIV-1 Cross Neutralizing Monoclonal Antibody 2F5 in complex with gp41 Peptides and Peptide Mimetics
To be Published
1UB6
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BU of 1ub6 by Molmil
Crystal structure of Antibody 19G2 with sera ligand
分子名称: antibody 19G2, alpha chain, beta chain
著者Beuscher, A.B, Wirsching, P, Lerner, R.A, Janda, K, Stevens, R.C.
登録日2003-03-30
公開日2004-04-20
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.12 Å)
主引用文献Structure and Dynamics of Blue Fluorescent Antibody 19G2 at Blue and Violet Fluorescent Temperatures
To be published
6GC2
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BU of 6gc2 by Molmil
AbLIFT: Antibody stability and affinity optimization by computational design of the variable light-heavy chain interface
分子名称: Heavy chain, Light Chain
著者Warszawski, S, Katz, A, Khmelnitsky, L, Ben Nissan, G, Javitt, G, Dym, O, Unger, T, Knop, O, Diskin, R, Albeck, S, Fass, D, Sharon, M, Fleishman, S.J.
登録日2018-04-17
公開日2019-05-01
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Optimizing antibody affinity and stability by the automated design of the variable light-heavy chain interfaces.
Plos Comput.Biol., 15, 2019
1UM6
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BU of 1um6 by Molmil
catalytic antibody 21h3
分子名称: antibody 21h3, H chain, L chain
著者Beuscher IV, A.E, Reuter, J, Olson, A.J, Romesberg, F.E, Schultz, P.G, Wirsching, P, Janda, K.D, Lerner, R.A, Stevens, R.C.
登録日2003-09-23
公開日2004-10-05
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural Studies of an Efficient Catalytic Antibody Operating by Ping-Pong and Induced Fit Mechanisms
To be Published
1RFD
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BU of 1rfd by Molmil
ANTI-COCAINE ANTIBODY M82G2
分子名称: Fab M82G2, Heavy Chain, Light Chain
著者Pozharski, E, Hewagama, A, Shanafelt, A.B, Petsko, G.A, Ringe, D.
登録日2003-11-07
公開日2003-11-18
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.09 Å)
主引用文献Diversity in hapten recognition: structural study of an anti-cocaine antibody M82G2.
J.Mol.Biol., 349, 2005
3IY3
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BU of 3iy3 by Molmil
Variable domains of the computer generated model (WAM) of Fab 8 fitted into the cryoEM reconstruction of the virus-Fab 8 complex
分子名称: antibody fragment from neutralizing antibody 8 (heavy chain), antibody fragment from neutralizing antibody 8 (light chain)
著者Hafenstein, S, Bowman, V.D, Sun, T, Nelson, C.D, Palermo, L.M, Chipman, P.R, Battisti, A.J, Parrish, C.R, Rossmann, M.G.
登録日2009-04-09
公開日2009-05-12
最終更新日2018-07-18
実験手法ELECTRON MICROSCOPY (11.1 Å)
主引用文献Structural comparison of different antibodies interacting with parvovirus capsids
J.Virol., 83, 2009
1QYG
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BU of 1qyg by Molmil
ANTI-COCAINE ANTIBODY M82G2 COMPLEXED WITH BENZOYLECGONINE
分子名称: 3-(BENZOYLOXY)-8-METHYL-8-AZABICYCLO[3.2.1]OCTANE-2-CARBOXYLIC ACID, FAB M82G2, HEAVY CHAIN, ...
著者Pozharski, E, Hewagama, A, Shanafelt, A, Petsko, G, Ringe, D.
登録日2003-09-10
公開日2003-09-23
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.81 Å)
主引用文献Diversity in hapten recognition: structural study of an anti-cocaine antibody M82G2.
J.Mol.Biol., 349, 2005
8JBJ
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BU of 8jbj by Molmil
Crystal structure of anti-PVRIG Fab
分子名称: antibody heavy chain, antibody light chain
著者Sun, J, Li, X.L, Song, J.
登録日2023-05-09
公開日2023-06-21
実験手法X-RAY DIFFRACTION (1.61 Å)
主引用文献Identification and characterization of an unexpected isomerization motif in CDRH2 that affects antibody activity.
Mabs, 15, 2023
1Q72
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BU of 1q72 by Molmil
Anti-Cocaine Antibody M82G2 Complexed with Cocaine
分子名称: COCAINE, Fab M82G2, Heavy chain, ...
著者Pozharski, E, Moulin, A, Hewagama, A, Shanafelt, A.B, Petsko, G.A, Ringe, D.
登録日2003-08-15
公開日2003-08-26
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Diversity in hapten recognition: structural study of an anti-cocaine antibody M82G2.
J.Mol.Biol., 349, 2005
3IY2
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BU of 3iy2 by Molmil
Variable domains of the computer generated model (WAM) of Fab 6 fitted into the cryoEM reconstruction of the virus-Fab 6 complex
分子名称: Antibody 6, heavy chain, light chain
著者Hafenstein, S, Bowman, V.D, Sun, T, Nelson, C.D, Palermo, L.M, Chipman, P.R, Battisti, A.J, Parrish, C.R, Rossmann, M.G.
登録日2009-04-09
公開日2009-05-12
最終更新日2018-07-18
実験手法ELECTRON MICROSCOPY (18 Å)
主引用文献Structural comparison of different antibodies interacting with parvovirus capsids
J.Virol., 83, 2009

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