1U8K

Crystal structure of the HIV-1 Cross Neutralizing Monoclonal Antibody 2F5 in complex with gp41 Peptide LELDKWASL

Summary for 1U8K

• Entry DOI: 10.2210/pdb1u8k/pdb
• Related: 1U8H 1U8I 1U8J 1U8L 1U8M 1U8N 1U8O 1U8P 1U8Q 1U91 1U92 1U93 1U95 2F5A 2F5B
• Descriptor: ANTIBODY 2F5 (LIGHT CHAIN), ANTIBODY 2F5 (HEAVY CHAIN), GP41 PEPTIDE, ... (4 entities in total)
• Functional Keywords: fab complex, hiv-1 neutralization, gp41 peptide, immune system
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 3
• Total formula weight: 49365.52

Authors

Bryson, S.,Julien, J.-P.,Pai, E.F. (deposition date: 2004-08-06, release date: 2004-10-05, Last modification date: 2024-11-06)

• Primary citation: Bryson, S.,Hynes, R.C.,Cunningham, A.,Dong, A.,Julien, J.-P.,Kunert, R.,Katinger, H.,Klein, M.,Pai, E.F.; Crystal structure of the HIV-1 Cross Neutralizing Monoclonal Antibody 2F5 in complex with gp41 Peptides and Peptide Mimetics; To be Published,

Experimental method

X-RAY DIFFRACTION (2.24 Å)