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2ZNX
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5-Fluorotryptophan Incorporated ScFv10 Complexed to Hen Egg Lysozyme
分子名称: 2-(2-{2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHANOL, Lysozyme C, ScFv
著者DeSantis, M.E, Acchione, M, Li, M, Walter, R.L, Wlodawer, A, Smith-Gill, S.
登録日2008-05-02
公開日2009-01-27
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Specific fluorine labeling of the HyHEL10 antibody affects antigen binding and dynamics
Biochemistry, 51, 2012
2ZNW
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Crystal Structure of ScFv10 in Complex with Hen Egg Lysozyme
分子名称: 2-(2-{2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHANOL, Lysozyme C, ScFv10
著者DeSantis, M.E, Acchione, M, Li, M, Walter, R.L, Wlodawer, A, Smith-Gill, S.
登録日2008-05-02
公開日2009-01-27
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (2.71 Å)
主引用文献Specific fluorine labeling of the HyHEL10 antibody affects antigen binding and dynamics
Biochemistry, 51, 2012
3D0L
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BU of 3d0l by Molmil
Crystal structure of the HIV-1 broadly neutralizing antibody 2F5 in complex with the gp41 FP-MPER Hyb3K construct 514GIGALFLGFLGAAGS528KK-Ahx-655KNEQELLELDKWASLWN671
分子名称: 2F5 heavy chain, 2F5 light chain, GLYCEROL, ...
著者Bryson, S, Julien, J.P, Pai, E.F.
登録日2008-05-01
公開日2008-10-07
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Structural details of HIV-1 recognition by the broadly neutralizing monoclonal antibody 2F5: epitope conformation, antigen-recognition loop mobility, and anion-binding site.
J.Mol.Biol., 384, 2008
2JJV
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Structure of human signal regulatory protein (sirp) beta(2)
分子名称: CHLORIDE ION, SIGNAL-REGULATORY PROTEIN BETA 1., SULFATE ION
著者Hatherley, D, Graham, S.C, Turner, J, Harlos, K, Stuart, D.I, Barclay, A.N.
登録日2008-04-22
公開日2008-08-05
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Paired Receptor Specificity Explained by Structures of Signal Regulatory Proteins Alone and Complexed with Cd47.
Mol.Cell, 31, 2008
2JJS
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Structure of human CD47 in complex with human signal regulatory protein (SIRP) alpha
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, IODIDE ION, LEUKOCYTE SURFACE ANTIGEN CD47, ...
著者Hatherley, D, Graham, S.C, Turner, J, Harlos, K, Stuart, D.I, Barclay, A.N.
登録日2008-04-22
公開日2008-08-05
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Paired receptor specificity explained by structures of signal regulatory proteins alone and complexed with CD47.
Mol. Cell, 31, 2008
2JJU
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BU of 2jju by Molmil
Structure of human signal regulatory protein (sirp) beta
分子名称: CHLORIDE ION, SIGNAL REGULATORY PROTEIN BETA-1, SULFATE ION
著者Hatherley, D, Graham, S.C, Turner, J, Harlos, K, Stuart, D.I, Barclay, A.N.
登録日2008-04-22
公開日2008-08-05
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.19 Å)
主引用文献Paired Receptor Specificity Explained by Structures of Signal Regulatory Proteins Alone and Complexed with Cd47.
Mol.Cell, 31, 2008
2JJW
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Structure of human signal regulatory protein (sirp) gamma
分子名称: SIGNAL REGULATORY PROTEIN GAMMA
著者Hatherley, D, Graham, S.C, Turner, J, Harlos, K, Stuart, D.I, Barclay, A.N.
登録日2008-04-22
公開日2008-08-05
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Paired Receptor Specificity Explained by Structures of Signal Regulatory Proteins Alone and Complexed with Cd47.
Mol.Cell, 31, 2008
2JJT
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Structure of human CD47 in complex with human signal regulatory protein (SIRP) alpha
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, LEUKOCYTE SURFACE ANTIGEN CD47, TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE SUBSTRATE 1
著者Hatherley, D, Graham, S.C, Turner, J, Harlos, K, Stuart, D.I, Barclay, A.N.
登録日2008-04-22
公開日2008-08-05
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Paired receptor specificity explained by structures of signal regulatory proteins alone and complexed with CD47.
Mol. Cell, 31, 2008
3CSP
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BU of 3csp by Molmil
Crystal structure of the DM2 mutant of myelin oligodendrocyte glycoprotein
分子名称: Myelin-oligodendrocyte glycoprotein
著者Breithaupt, C, Schafer, B, Pellkofer, H, Huber, R, Linington, C, Jacob, U.
登録日2008-04-10
公開日2008-10-21
最終更新日2021-10-20
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Demyelinating myelin oligodendrocyte glycoprotein-specific autoantibody response is focused on one dominant conformational epitope region in rodents
J.Immunol., 181, 2008
3CMO
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HIV neutralizing monoclonal antibody YZ18
分子名称: Fab heavy chain, Fab light chain
著者Jin, L, Prasad, V, Paul, S.
登録日2008-03-24
公開日2008-08-05
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献HIV neutralizing monoclonal antibody YZ18
TO BE PUBLISHED
3CM9
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BU of 3cm9 by Molmil
Solution Structure of Human SIgA2
分子名称: Immunoglobulin heavy chain, Immunoglobulin light chain, Secretory component
著者Bonner, A, Almogren, A, Furtado, P.B, Kerr, M.A, Perkins, S.J.
登録日2008-03-21
公開日2008-12-30
最終更新日2024-02-21
実験手法SOLUTION SCATTERING
主引用文献The nonplanar secretory IgA2 and near planar secretory IgA1 solution structures rationalize their different mucosal immune responses.
J.Biol.Chem., 284, 2009
3CHN
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BU of 3chn by Molmil
Solution structure of human secretory IgA1
分子名称: Ig alpha-1 chain C region, Immunoglobulin kappa light chain, Secretory component
著者Bonner, A, Almogren, A, Furtado, P.B, Kerr, M.A, Perkins, S.J.
登録日2008-03-10
公開日2008-12-30
最終更新日2024-02-21
実験手法SOLUTION SCATTERING
主引用文献Location of secretory component on the Fc edge of dimeric IgA1 reveals insight into the role of secretory IgA1 in mucosal immunity.
Mucosal Immunol, 2, 2009
3CFJ
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Crystal structure of catalytic elimination antibody 34E4, orthorhombic crystal form
分子名称: CATALYTIC ANTIBODY FAB 34E4 HEAVY CHAIN fusion, CATALYTIC ANTIBODY FAB 34E4 LIGHT CHAIN fusion, GLYCEROL, ...
著者Debler, E.W, Wilson, I.A.
登録日2008-03-04
公開日2008-04-15
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Conformational isomerism can limit antibody catalysis.
J.Biol.Chem., 283, 2008
3CFK
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BU of 3cfk by Molmil
Crystal structure of catalytic elimination antibody 34E4, triclinic crystal form
分子名称: 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CADMIUM ION, CATALYTIC ANTIBODY FAB 34E4 HEAVY CHAIN,Uncharacterized protein, ...
著者Debler, E.W, Wilson, I.A.
登録日2008-03-04
公開日2008-04-15
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Conformational isomerism can limit antibody catalysis.
J.Biol.Chem., 283, 2008
3CDY
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BU of 3cdy by Molmil
AL-09 H87Y, immunoglobulin light chain variable domain
分子名称: IMMUNOGLOBULIN LIGHT CHAIN
著者Baden, E.M, Randles, E.G, Aboagye, A.K, Thompson, J.R, Ramirez-Alvarado, M.
登録日2008-02-27
公開日2008-09-02
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.43 Å)
主引用文献Structural insights into the role of mutations in amyloidogenesis.
J.Biol.Chem., 283, 2008
3CDC
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BU of 3cdc by Molmil
kI O18/O8 N34I/Y87H immunoglobulin light chain variable domain
分子名称: Light Chain Amyloidogenic
著者Baden, E.M, Randles, E.G, Thompson, J.R, Ramirez-Alvarado, M.
登録日2008-02-26
公開日2008-09-02
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.53 Å)
主引用文献Structural insights into the role of mutations in amyloidogenesis.
J.Biol.Chem., 283, 2008
3CDF
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kI O18/O8 Y87H immunoglobulin light chain variable domain
分子名称: IMMUNOGLOBULIN LIGHT CHAIN
著者Baden, E.M, Randles, E.G, Thompson, J.R, Ramirez-Alvarado, M.
登録日2008-02-26
公開日2008-09-02
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.53 Å)
主引用文献Structural insights into the role of mutations in amyloidogenesis.
J.Biol.Chem., 283, 2008
2ZG2
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Crystal Structure of Two N-terminal Domains of Native Siglec-5
分子名称: Sialic acid-binding Ig-like lectin 5
著者Zhuravleva, M.A, Sun, P.D.
登録日2008-01-17
公開日2008-02-05
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Structural implications of Siglec-5-mediated sialoglycan recognition
J.Mol.Biol., 375, 2008
2ZG1
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BU of 2zg1 by Molmil
Crystal Structure of Two N-terminal Domains of Siglec-5 in Complex with 6'-Sialyllactose
分子名称: N-acetyl-alpha-neuraminic acid, Sialic acid-binding Ig-like lectin 5
著者Zhuravleva, M.A, Sun, P.D.
登録日2008-01-17
公開日2008-02-05
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structural implications of Siglec-5-mediated sialoglycan recognition
J.Mol.Biol., 375, 2008
2ZG3
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BU of 2zg3 by Molmil
Crystal Structure of Two N-terminal Domains of Native Siglec-5 in Complex with 3'-Sialyllactose
分子名称: N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-4)-beta-D-glucopyranose, Sialic acid-binding Ig-like lectin 5
著者Zhuravleva, M.A, Sun, P.D.
登録日2008-01-17
公開日2008-02-05
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural implications of Siglec-5-mediated sialoglycan recognition
J.Mol.Biol., 375, 2008
3BX7
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BU of 3bx7 by Molmil
Engineered Human Lipocalin 2 (LCN2) in Complex with the Extracellular Domain of Human CTLA-4
分子名称: CYTOTOXIC T-LYMPHOCYTE-ASSOCIATED ANTIGEN 4, ENGINEERED HUMAN LIPOCALIN 2
著者Schonfeld, D.L, Chatwell, L, Skerra, A.
登録日2008-01-11
公開日2009-01-20
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献High affinity molecular recognition and functional blockade of CTLA-4 by an engineered human lipocalin
To be Published
3BQU
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Crystal Structure of the 2F5 Fab'-3H6 Fab Complex
分子名称: 2F5 Fab' heavy chain, 2F5 Fab' light chain, 3H6 Fab heavy chain, ...
著者Bryson, S, Julien, J.-P, Isenman, D.E, Kunert, R, Katinger, H, Pai, E.F.
登録日2007-12-20
公開日2008-10-21
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Crystal structure of the complex between the F(ab)' fragment of the cross-neutralizing anti-HIV-1 antibody 2F5 and the F(ab) fragment of its anti-idiotypic antibody 3H6.
J.Mol.Biol., 382, 2008
3BP6
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Crystal structure of the mouse PD-1 Mutant and PD-L2 complex
分子名称: GLYCEROL, Programmed cell death 1 ligand 2, Programmed cell death protein 1
著者Yan, Q, Lazar-Molnar, E, Cao, E, Ramagopal, U.A, Toro, R, Nathenson, S.G, Almo, S.C.
登録日2007-12-18
公開日2009-02-24
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Crystal structure of the mouse PD-1 A99L and PD-L2 complex
To be published
3BP5
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Crystal structure of the mouse PD-1 and PD-L2 complex
分子名称: GLYCEROL, Programmed cell death 1 ligand 2, Programmed cell death protein 1
著者Yan, Q, Lazar-Molnar, E, Cao, E, Ramagopal, U.A, Toro, R, Nathenson, S.G, Almo, S.C.
登録日2007-12-18
公開日2008-07-15
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal structure of the complex between programmed death-1 (PD-1) and its ligand PD-L2.
Proc.Natl.Acad.Sci.Usa, 105, 2008
3BN9
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Crystal Structure of MT-SP1 in complex with Fab Inhibitor E2
分子名称: 1,2-ETHANEDIOL, E2 Fab Heavy Chain, E2 Fab Light Chain, ...
著者Farady, C.J, Schneider, E.L, Egea, P.F, Goetz, D.H, Craik, C.S.
登録日2007-12-13
公開日2008-09-09
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.173 Å)
主引用文献Structure of an Fab-protease complex reveals a highly specific non-canonical mechanism of inhibition
J.Mol.Biol., 380, 2008

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