6QCI
| Structure of XIAP-BIR1 V86E mutant | 分子名称: | DI(HYDROXYETHYL)ETHER, E3 ubiquitin-protein ligase XIAP, SODIUM ION, ... | 著者 | Sorrentino, L, Cossu, F, Milani, M, Mastrangelo, E. | 登録日 | 2018-12-28 | 公開日 | 2019-05-01 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structure-Activity Relationship of NF023 Derivatives Binding to XIAP-BIR1. Chemistryopen, 8, 2019
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7QYJ
| The structure of T. forsythia NanH | 分子名称: | BNR/Asp-box repeat protein | 著者 | Rafferty, J, Stafford, G, Satur, M. | 登録日 | 2022-01-28 | 公開日 | 2022-12-07 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.11 Å) | 主引用文献 | Structural and functional characterisation of a stable, broad-specificity multimeric sialidase from the oral pathogen Tannerella forsythia. Biochem.J., 479, 2022
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6QCM
| Cryo em structure of the Listeria stressosome | 分子名称: | RsbR protein, RsbR protein,RsbR protein, RsbS protein | 著者 | Williams, A.H, Redzej, A, Waksman, G, Cossart, P. | 登録日 | 2018-12-28 | 公開日 | 2019-08-21 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (4.21 Å) | 主引用文献 | The cryo-electron microscopy supramolecular structure of the bacterial stressosome unveils its mechanism of activation. Nat Commun, 10, 2019
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7QFI
| Crystal structure of S-layer protein SlpX from Lactobacillus acidophilus, domain I (aa 31-182) | 分子名称: | CALCIUM ION, SlpX | 著者 | Sagmeister, T, Damisch, E, Millan, C, Uson, I, Eder, M, Pavkov-Keller, T. | 登録日 | 2021-12-06 | 公開日 | 2022-12-21 | 最終更新日 | 2024-06-19 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | The molecular architecture of Lactobacillus S-layer: Assembly and attachment to teichoic acids. Proc.Natl.Acad.Sci.USA, 121, 2024
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6QDZ
| P38 alpha complex with AR117045 | 分子名称: | 1-[5-~{tert}-butyl-2-(4-methylphenyl)pyrazol-3-yl]-3-[(1~{S},4~{S})-4-[(3-propan-2-yl-[1,2,4]triazolo[4,3-a]pyridin-6-yl)oxy]-1,2,3,4-tetrahydronaphthalen-1-yl]urea, 2-fluoro-4-[4-(4-fluorophenyl)-1H-pyrazol-3-yl]pyridine, Mitogen-activated protein kinase 14 | 著者 | Brown, D.G, Hurley, C, Irving, S.L. | 登録日 | 2019-01-03 | 公開日 | 2020-01-29 | 最終更新日 | 2024-05-15 | 実験手法 | X-RAY DIFFRACTION (1.73 Å) | 主引用文献 | P38 alpha complex with AR117045 To Be Published
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6QE9
| The X-ray structure of the adduct formed in the reaction between bovine pancreatic ribonuclease and complex I, a pentacoordinate Pt(II) compound containing 2,9-dimethyl-1,10-phenanthroline, dimethylfumarate, methyl and iodine as ligands | 分子名称: | Ribonuclease pancreatic, SULFATE ION, pentacoordinate Pt(II) compound | 著者 | Merlino, A, Ferraro, G. | 登録日 | 2019-01-07 | 公開日 | 2019-02-27 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.03 Å) | 主引用文献 | Reaction with Proteins of a Five-Coordinate Platinum(II) Compound. Int J Mol Sci, 20, 2019
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7QFK
| Crystal structure of S-layer protein SlpX from Lactobacillus acidophilus, domain II, Co-Crystallization with HgCl2, Mutation Ser316Cys (aa 194-362) | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, BROMIDE ION, CHLORIDE ION, ... | 著者 | Sagmeister, T, Pavkov-Keller, T, Buhlheller, C. | 登録日 | 2021-12-06 | 公開日 | 2022-12-21 | 最終更新日 | 2024-06-19 | 実験手法 | X-RAY DIFFRACTION (2.48 Å) | 主引用文献 | The molecular architecture of Lactobacillus S-layer: Assembly and attachment to teichoic acids. Proc.Natl.Acad.Sci.USA, 121, 2024
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7QTR
| GB1 in mammalian cells, 50 uM | 分子名称: | Immunoglobulin G-binding protein G | 著者 | Gerez, J.A, Prymaczok, N.C, Kadavath, H, Gosh, D, Butikofer, M, Guntert, P, Riek, R. | 登録日 | 2022-01-15 | 公開日 | 2022-12-21 | 最終更新日 | 2024-06-19 | 実験手法 | SOLUTION NMR | 主引用文献 | Protein structure determination in human cells by in-cell NMR and a reporter system to optimize protein delivery or transexpression. Commun Biol, 5, 2022
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4FF6
| Mycobacterium tuberculosis DprE1 in complex with CT325 - monoclinic crystal form | 分子名称: | 3-(hydroxyamino)-N-[(1R)-1-phenylethyl]-5-(trifluoromethyl)benzamide, FLAVIN-ADENINE DINUCLEOTIDE, IMIDAZOLE, ... | 著者 | Batt, S.M, Besra, G.S, Futterer, K. | 登録日 | 2012-05-31 | 公開日 | 2012-07-04 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Structural basis of inhibition of Mycobacterium tuberculosis DprE1 by benzothiazinone inhibitors. Proc.Natl.Acad.Sci.USA, 109, 2012
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7QY9
| The structure of T.forsythia NanH with oseltamivir | 分子名称: | (3R,4R,5S)-4-(acetylamino)-5-amino-3-(pentan-3-yloxy)cyclohex-1-ene-1-carboxylic acid, BNR/Asp-box repeat protein | 著者 | Rafferty, J, Stafford, G, Satur, M. | 登録日 | 2022-01-27 | 公開日 | 2022-12-07 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.92 Å) | 主引用文献 | Structural and functional characterisation of a stable, broad-specificity multimeric sialidase from the oral pathogen Tannerella forsythia. Biochem.J., 479, 2022
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8DW9
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6Q50
| Structure of MPT-4, a mannose phosphorylase from Leishmania mexicana, in complex with phosphate ion | 分子名称: | 1,2-ETHANEDIOL, MPT-4, PHOSPHATE ION, ... | 著者 | Sobala, L.F, Males, A, Bastidas, L.M, Ward, T, Sernee, M.F, Ralton, J.E, Nero, T.L, Cobbold, S, Kloehn, J, Viera-Lara, M, Stanton, L, Hanssen, E, Parker, M.W, Williams, S.J, McConville, M.J, Davies, G.J. | 登録日 | 2018-12-06 | 公開日 | 2019-09-25 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | A Family of Dual-Activity Glycosyltransferase-Phosphorylases Mediates Mannogen Turnover and Virulence in Leishmania Parasites. Cell Host Microbe, 26, 2019
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7QZ3
| The structure of T. forsythia NanH | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, BNR/Asp-box repeat protein | 著者 | Rafferty, J, Stafford, G, Satur, M. | 登録日 | 2022-01-30 | 公開日 | 2022-12-07 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.97 Å) | 主引用文献 | Structural and functional characterisation of a stable, broad-specificity multimeric sialidase from the oral pathogen Tannerella forsythia. Biochem.J., 479, 2022
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6Q55
| Crystal structure of Cryptosporidium hominis CPSF3 in complex with Compound 61 | 分子名称: | 3-[7,7-bis(oxidanyl)-8-oxa-7-boranuidabicyclo[4.3.0]nona-1(6),2,4-trien-5-yl]propanoic acid, Cleavage and Polyadenylation Specificity Factor 3 (CPSF3), GLYCEROL, ... | 著者 | Palencia, A, Swale, C. | 登録日 | 2018-12-07 | 公開日 | 2019-11-20 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Metal-captured inhibition of pre-mRNA processing activity by CPSF3 controls Cryptosporidium infection. Sci Transl Med, 11, 2019
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6QF8
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7QTS
| GB1 in mammalian cells, 10 uM | 分子名称: | Immunoglobulin G-binding protein G | 著者 | Gerez, J.A, Prymaczok, N.C, Kadavath, H, Gosh, D, Butikofer, M, Guntert, P, Riek, R. | 登録日 | 2022-01-15 | 公開日 | 2022-12-21 | 最終更新日 | 2024-06-19 | 実験手法 | SOLUTION NMR | 主引用文献 | Protein structure determination in human cells by in-cell NMR and a reporter system to optimize protein delivery or transexpression. Commun Biol, 5, 2022
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6QFR
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7QH1
| Discovery and development of a novel inhaled antivirulence therapy for the treatment of Pseudomonas aeruginosa infections in patients with chronic respiratory disease | 分子名称: | 2-[2-[[5-[3-[bis(2-hydroxyethyl)-methyl-$l^{4}-azanyl]propoxy]-6-methoxy-1,3-benzothiazol-2-yl]methylcarbamoyl]-5,6-bis(fluoranyl)-1,3-dihydroinden-2-yl]ethanoic acid, CALCIUM ION, Keratinase KP2, ... | 著者 | Leonard, P.M, Davies, D, Pallin, T.D. | 登録日 | 2021-12-10 | 公開日 | 2022-12-21 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.74 Å) | 主引用文献 | Chemical Optimization of Selective Pseudomonas aeruginosa LasB Elastase Inhibitors and Their Impact on LasB-Mediated Activation of IL-1 beta in Cellular and Animal Infection Models. Acs Infect Dis., 9, 2023
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7QYP
| The structure of T. forsythia NanH | 分子名称: | 1,2-ETHANEDIOL, BNR/Asp-box repeat protein | 著者 | Rafferty, J, Stafford, G, Satur, M. | 登録日 | 2022-01-28 | 公開日 | 2022-12-07 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.659 Å) | 主引用文献 | Structural and functional characterisation of a stable, broad-specificity multimeric sialidase from the oral pathogen Tannerella forsythia. Biochem.J., 479, 2022
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6Q6C
| Pore-modulating toxins exploit inherent slow inactivation to block K+ channels | 分子名称: | 1,2-ETHANEDIOL, Kunitz-type conkunitzin-S1, NITRATE ION, ... | 著者 | Karbat, I, Gueta, H, Fine, S, Szanto, T, Hamer-Rogotner, S, Dym, O, Frolow, F, Gordon, D, Panyi, G, Gurevitz, M, Reuveny, E. | 登録日 | 2018-12-10 | 公開日 | 2019-08-21 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | 主引用文献 | Pore-modulating toxins exploit inherent slow inactivation to block K+channels. Proc.Natl.Acad.Sci.USA, 116, 2019
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7QFJ
| Crystal structure of S-layer protein SlpX from Lactobacillus acidophilus, domain II (aa 194-362) | 分子名称: | SlpX | 著者 | Sagmeister, T, Pavkov-Keller, T, Buhlheller, C, Baek, M, Read, R, Baker, D. | 登録日 | 2021-12-06 | 公開日 | 2022-12-21 | 最終更新日 | 2024-06-19 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | The molecular architecture of Lactobacillus S-layer: Assembly and attachment to teichoic acids. Proc.Natl.Acad.Sci.USA, 121, 2024
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7QFG
| Crystal structure of S-layer protein SlpA from Lactobacillus acidophilus, domain III (aa 309-444) | 分子名称: | 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, S-layer protein | 著者 | Sagmeister, T, Eder, M, Pavkov-Keller, T. | 登録日 | 2021-12-06 | 公開日 | 2022-12-21 | 最終更新日 | 2024-06-19 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | The molecular architecture of Lactobacillus S-layer: Assembly and attachment to teichoic acids. Proc.Natl.Acad.Sci.USA, 121, 2024
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7QGW
| Sulfonated Calpeptin is a promising drug candidate against SARS-CoV-2 infections | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, CHLORIDE ION, Calpeptin, ... | 著者 | Loboda, J, Karnicar, K, Lindic, N, Usenik, A, Lieske, J, Meents, A, Guenther, S, Reinke, P.Y.A, Falke, S, Ewert, W, Turk, D. | 登録日 | 2021-12-10 | 公開日 | 2022-12-21 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | 主引用文献 | Calpeptin is a potent cathepsin inhibitor and drug candidate for SARS-CoV-2 infections. Commun Biol, 6, 2023
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6QH3
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6QIM
| Structure of AtPIP2;4 | 分子名称: | Probable aquaporin PIP2-4 | 著者 | Schoebel, S, Wang, H. | 登録日 | 2019-01-21 | 公開日 | 2019-11-20 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (3.7 Å) | 主引用文献 | Characterization of aquaporin-driven hydrogen peroxide transport. Biochim Biophys Acta Biomembr, 1862, 2020
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