PDB: 95574 件ウェブページステータス検索Chemie searchBIRD

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7PDT	Crystal structure of a mutated form of RXRalpha ligand binding domain in complex with BMS649 and a coactivator fragment 分子名称: 4-[2-(5,5,8,8-TETRAMETHYL-5,6,7,8-TETRAHYDRO-NAPHTHALEN-2-YL)-[1,3]DIOXOLAN-2-YL]-BENZOIC ACID, Nuclear receptor coactivator 2, Retinoic acid receptor RXR-alpha 著者 le Maire, A, Bourguet, W, Guee, L. 登録日 2021-08-07 公開日 2022-08-03 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (3.3 Å) 主引用文献 Design and in vitro characterization of RXR variants as tools to investigate the biological role of endogenous rexinoids. J.Mol.Endocrinol., 69, 2022
7L5E	Crystal Structure of KPT-330 bound to CRM1 (537-DLTVK-541 to GLCEQ) 分子名称: Exportin-1, GLYCEROL, GTP-binding nuclear protein Ran, ... 著者 Baumhardt, J.M, Chook, Y.M. 登録日 2020-12-21 公開日 2021-01-27 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.944 Å) 主引用文献 Recurrent XPO1 mutations alter pathogenesis of chronic lymphocytic leukemia. J Hematol Oncol, 14, 2021
1N90	FOLLOWING THE C HEME REDUCTION IN NITRITE REDUCTASE FROM PSEUDOMONAS AERUGINOSA 分子名称: HEME C, HEME D, NITRITE REDUCTASE 著者 Nurizzo, D, Tegoni, M, Cambillau, C. 登録日 1998-09-04 公開日 1999-06-15 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Does the reduction of c heme trigger the conformational change of crystalline nitrite reductase? J.Biol.Chem., 274, 1999
6IP4	Crystal structure of Arabidopsis thaliana JMJ13 catalytic domain in complex with NOG and an H3K27me3 peptide 分子名称: Arabidopsis JMJ13, Histone H3.2, N-OXALYLGLYCINE, ... 著者 Hu, H, Du, J. 登録日 2018-11-02 公開日 2019-04-10 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 The Arabidopsis H3K27me3 demethylase JUMONJI 13 is a temperature and photoperiod dependent flowering repressor. Nat Commun, 10, 2019
1NEY	Triosephosphate Isomerase in Complex with DHAP 分子名称: 1,3-DIHYDROXYACETONEPHOSPHATE, triosephosphate isomerase 著者 Jogl, G, Rozovsky, S, McDermott, A.E, Tong, L. 登録日 2002-12-12 公開日 2003-01-07 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (1.2 Å) 主引用文献 Optimal alignment for enzymatic proton transfer: Structure of the Michaelis complex of triosephosphate isomerase at 1.2-A resolution. Proc.Natl.Acad.Sci.USA, 100, 2003
1NFW	CRYSTAL STRUCTURE OF HUMAN COAGULATION FACTOR XA COMPLEXED WITH RPR209685 分子名称: 4-{[(E)-2-(5-CHLOROTHIEN-2-YL)VINYL]SULFONYL}-1-(1H-PYRROLO[3,2-C]PYRIDIN-2-YLMETHYL)PIPERAZIN-2-ONE, CALCIUM ION, COAGULATION FACTOR XA, ... 著者 Maignan, S, Guilloteau, J.P. 登録日 2002-12-16 公開日 2003-02-25 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Molecular structures of human Factor Xa complexed with ketopiperazine inhibitors: preference for a neutral group in the S1 pocket. J.Med.Chem., 46, 2003
1NAI	UDP-GALACTOSE 4-EPIMERASE FROM ESCHERICHIA COLI, OXIDIZED 分子名称: 1,3-PROPANDIOL, DI(HYDROXYETHYL)ETHER, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... 著者 Thoden, J.B, Frey, P.A, Holden, H.M. 登録日 1995-11-22 公開日 1996-12-23 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Crystal structures of the oxidized and reduced forms of UDP-galactose 4-epimerase isolated from Escherichia coli. Biochemistry, 35, 1996
8AB2	Crystal Structure of the Lactate Dehydrogenase of Cyanobacterium Aponinum in its apo form. 分子名称: 1,2-ETHANEDIOL, L-lactate dehydrogenase, TERBIUM(III) ION, ... 著者 Robin, A.Y, Girard, E, Madern, D. 登録日 2022-07-04 公開日 2022-08-03 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Deciphering Evolutionary Trajectories of Lactate Dehydrogenases Provides New Insights into Allostery. Mol.Biol.Evol., 40, 2023
8AAU	LIM Domain Kinase 1 (LIMK1) bound to LIMKi3 分子名称: 1,2-ETHANEDIOL, LIM domain kinase 1, MAGNESIUM ION, ... 著者 Mathea, S, Salah, E, Hanke, T, Knapp, S. 登録日 2022-07-03 公開日 2022-08-10 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.74 Å) 主引用文献 Development and Characterization of Type I, Type II, and Type III LIM-Kinase Chemical Probes. J.Med.Chem., 65, 2022
7KPX	Structure of the yeast CKM 分子名称: Mediator of RNA polymerase II transcription subunit 12, Mediator of RNA polymerase II transcription subunit 13, Meiotic mRNA stability protein kinase SSN3, ... 著者 Li, Y.C, Chao, T.C, Kim, H.J, Cholko, T, Chen, S.F, Nakanishi, K, Chang, C.E, Murakami, K, Garcia, B.A, Boyer, T.G, Tsai, K.L. 登録日 2020-11-12 公開日 2021-01-27 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (4.4 Å) 主引用文献 Structure and noncanonical Cdk8 activation mechanism within an Argonaute-containing Mediator kinase module. Sci Adv, 7, 2021
6J0E	Structures of two ArsR As(III)-responsive repressors: implications for the mechanism of derepression 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, ARSENIC, Arsenic responsive repressor ArsR 著者 Prabaharan, C, Kandavelu, P, Packianathan, C, Rosen, P.B, Thiyagarajan, S. 登録日 2018-12-24 公開日 2019-07-03 最終更新日 2024-05-29 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Structures of two ArsR As(III)-responsive transcriptional repressors: Implications for the mechanism of derepression. J.Struct.Biol., 207, 2019
8AX5	Crystal structure of a CGRP receptor ectodomain heterodimer bound to macrocyclic inhibitor HTL0029881 分子名称: (1~{R},10~{R},20~{E})-12-methyl-10-[(7-methyl-2~{H}-indazol-5-yl)methyl]-15,18-dioxa-9,12,24,26-tetrazapentacyclo[20.5.2.1^{1,4}.1^{3,7}.0^{25,28}]hentriaconta-3,5,7(30),20,22,24,28-heptaene-8,11,27-trione, Maltose/maltodextrin-binding periplasmic protein,Receptor activity-modifying protein 1,Calcitonin gene-related peptide type 1 receptor, TETRAETHYLENE GLYCOL, ... 著者 Southall, S.M, Watson, S.P. 登録日 2022-08-30 公開日 2022-12-07 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.75 Å) 主引用文献 Novel Macrocyclic Antagonists of the CGRP Receptor Part 2: Stereochemical Inversion Induces an Unprecedented Binding Mode. Acs Med.Chem.Lett., 13, 2022
8APP	AbLys1 endolysin from Acinetobacter baumannii phage AbTZA1 分子名称: Endolysin, GLYCEROL, PHOSPHATE ION 著者 Premetis, G.E, Stathi, A, Papageorgiou, A.C, Labrou, N.E. 登録日 2022-08-10 公開日 2022-12-07 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (1.82 Å) 主引用文献 Characterization of a glycoside hydrolase endolysin from Acinetobacter baumannii phage AbTZA1 with high antibacterial potency and novel structural features. Febs J., 290, 2023
8AX6	Crystal structure of a CGRP receptor ectodomain heterodimer bound to macrocyclic inhibitor HTL0029882 分子名称: (1~{S},10~{R},20~{E})-12-methyl-10-[(7-methyl-2~{H}-indazol-5-yl)methyl]-15,18-dioxa-9,12,24,26-tetrazapentacyclo[20.5.2.1^{1,4}.1^{3,7}.0^{25,28}]hentriaconta-3(30),4,6,20,22,24,28-heptaene-8,11,27-trione, Maltose/maltodextrin-binding periplasmic protein,Receptor activity-modifying protein 1,Calcitonin gene-related peptide type 1 receptor, TETRAETHYLENE GLYCOL, ... 著者 Southall, S.M, Watson, S.P. 登録日 2022-08-30 公開日 2022-12-07 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Novel Macrocyclic Antagonists of the CGRP Receptor Part 2: Stereochemical Inversion Induces an Unprecedented Binding Mode. Acs Med.Chem.Lett., 13, 2022
1NRJ	Signal Recognition Particle Receptor Beta-Subunit in Complex with the SRX Domain from the Alpha-Subunit 分子名称: 1,2-ETHANEDIOL, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... 著者 Schwartz, T. 登録日 2003-01-24 公開日 2003-03-25 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Structural Basis for the Function of the beta Subunit of the Eukaryotic Signal Recognition Particle Receptor Cell(Cambridge,Mass.), 112, 2003
8AX7	Crystal structure of a CGRP receptor ectodomain heterodimer bound to macrocyclic inhibitor HTL0031448 分子名称: (1~{S},10~{R},20~{E})-10-[(1,7-dimethylindazol-5-yl)methyl]-12-methyl-15,18-dioxa-9,12,24,26-tetrazapentacyclo[20.5.2.1^{1,4}.1^{3,7}.0^{25,28}]hentriaconta-3(30),4,6,20,22,24,28-heptaene-8,11,27-trione, ACETATE ION, Maltose/maltodextrin-binding periplasmic protein,Receptor activity-modifying protein 1,Calcitonin gene-related peptide type 1 receptor, ... 著者 Southall, S.M, Watson, S.P. 登録日 2022-08-30 公開日 2022-12-07 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Novel Macrocyclic Antagonists of the CGRP Receptor Part 2: Stereochemical Inversion Induces an Unprecedented Binding Mode. Acs Med.Chem.Lett., 13, 2022
1NQO	Glyceraldehyde-3-Phosphate Dehydrogenase Mutant With Cys 149 Replaced By Ser Complexed With Nad+ and D-Glyceraldehyde-3-Phosphate 分子名称: GLYCERALDEHYDE-3-PHOSPHATE, Glyceraldehyde 3-phosphate dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE 著者 Didierjean, C, Corbier, C, Fatih, M, Favier, F, Boschi-Muller, S, Branlant, G, Aubry, A. 登録日 2003-01-22 公開日 2003-04-22 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (2.01 Å) 主引用文献 Crystal structure of two ternary complexes of phosphorylating Glyceraldehyde-3-Phosphate Dehydrogenase from Bacillus stearothermophilus with NAD and D-Glyceraldehyde-3-Phosphate J.Biol.Chem., 278, 2003
1NU6	Crystal structure of human Dipeptidyl Peptidase IV (DPP-IV) 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Dipeptidyl peptidase IV, MERCURY (II) ION 著者 Hennig, M, Stihle, M, Thoma, R, Ruf, A. 登録日 2003-01-31 公開日 2003-08-26 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structural Basis of Proline-Specific Exopeptidase Activity as Observed in Human Dipeptidyl Peptidase-IV. Structure, 11, 2003
1NV5	Fructose-1,6-Bisphosphatase Complex with Magnesium, Fructose-6-Phosphate, Phosphate, EDTA and Thallium (5 mM) 分子名称: 6-O-phosphono-beta-D-fructofuranose, Fructose-1,6-bisphosphatase, MAGNESIUM ION, ... 著者 Choe, J, Iancu, C.V, Fromm, H.J, Honzatko, R.B. 登録日 2003-02-02 公開日 2003-07-08 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Interaction of Tl+ with product complexes of fructose-1,6-bisphosphatase J.BIOL.CHEM., 278, 2003
146L	ROLE OF BACKBONE FLEXIBILITY IN THE ACCOMMODATION OF VARIANTS THAT REPACK THE CORE OF T4 LYSOZYME 分子名称: BETA-MERCAPTOETHANOL, CHLORIDE ION, T4 LYSOZYME 著者 Baldwin, E, Matthews, B.W. 登録日 1993-10-15 公開日 1994-01-31 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 The role of backbone flexibility in the accommodation of variants that repack the core of T4 lysozyme. Science, 262, 1993
160L	CONTROL OF ENZYME ACTIVITY BY AN ENGINEERED DISULFIDE BOND 分子名称: BETA-MERCAPTOETHANOL, CHLORIDE ION, T4 LYSOZYME 著者 Blaber, M, Matthews, B.W. 登録日 1994-06-20 公開日 1994-08-31 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Alanine scanning mutagenesis of the alpha-helix 115-123 of phage T4 lysozyme: effects on structure, stability and the binding of solvent. J.Mol.Biol., 246, 1995
1O5Q	Crystal Structure of Pyruvate and Mg2+ bound 2-methylisocitrate lyase (PrpB) from Salmonella typhimurium 分子名称: MAGNESIUM ION, PYRUVIC ACID, Probable methylisocitrate lyase 著者 Simanshu, D.K, Murthy, M.R.N. 登録日 2003-10-04 公開日 2003-11-25 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Crystal structure of Salmonella typhimurium 2-methylisocitrate lyase (PrpB) and its complex with pyruvate and Mg(2+) Biochem.Biophys.Res.Commun., 311, 2003
6J3Z	Structure of C2S1M1-type PSII-FCPII supercomplex from diatom 分子名称: (3S,3'S,5R,5'R,6S,6'R,8'R)-3,5'-dihydroxy-8-oxo-6',7'-didehydro-5,5',6,6',7,8-hexahydro-5,6-epoxy-beta,beta-caroten-3'-yl acetate, 1,2-DI-O-ACYL-3-O-[6-DEOXY-6-SULFO-ALPHA-D-GLUCOPYRANOSYL]-SN-GLYCEROL, 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, ... 著者 Nagao, R, Kato, K, Shen, J.R, Miyazaki, N, Akita, F. 登録日 2019-01-07 公開日 2019-08-07 最終更新日 2019-11-06 実験手法 ELECTRON MICROSCOPY (3.6 Å) 主引用文献 Structural basis for energy harvesting and dissipation in a diatom PSII-FCPII supercomplex. Nat.Plants, 5, 2019
1NSK	THE CRYSTAL STRUCTURE OF A HUMAN NUCLEOSIDE DIPHOSPHATE KINASE, NM23-H2 分子名称: NUCLEOSIDE DIPHOSPHATE KINASE 著者 Williams, R.L, Perisic, O. 登録日 1995-07-04 公開日 1995-10-15 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 The crystal structure of a human nucleoside diphosphate kinase, NM23-H2. J.Mol.Biol., 251, 1995
6J3Y	Structure of C2S2-type PSII-FCPII supercomplex from diatom 分子名称: (3S,3'S,5R,5'R,6S,6'R,8'R)-3,5'-dihydroxy-8-oxo-6',7'-didehydro-5,5',6,6',7,8-hexahydro-5,6-epoxy-beta,beta-caroten-3'-yl acetate, 1,2-DI-O-ACYL-3-O-[6-DEOXY-6-SULFO-ALPHA-D-GLUCOPYRANOSYL]-SN-GLYCEROL, 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, ... 著者 Nagao, R, Kato, K, Shen, J.R, Miyazaki, N, Akita, F. 登録日 2019-01-07 公開日 2019-08-07 最終更新日 2019-11-06 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 Structural basis for energy harvesting and dissipation in a diatom PSII-FCPII supercomplex. Nat.Plants, 5, 2019

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