1O5Q

Crystal Structure of Pyruvate and Mg2+ bound 2-methylisocitrate lyase (PrpB) from Salmonella typhimurium

Summary for 1O5Q

• Entry DOI: 10.2210/pdb1o5q/pdb
• Related: 1UJQ
• Descriptor: Probable methylisocitrate lyase, MAGNESIUM ION, PYRUVIC ACID, ... (4 entities in total)
• Functional Keywords: prpb, lyase, methylisocitrate, methylcitrate cycle, propionate metabolism, helix swapping
• Biological source: Salmonella enterica subsp. enterica serovar Typhimurium
• Total number of polymer chains: 4
• Total formula weight: 133508.76

Authors

Simanshu, D.K.,Murthy, M.R.N. (deposition date: 2003-10-04, release date: 2003-11-25, Last modification date: 2023-11-15)

• Primary citation: Simanshu, D.K.,Satheshkumar, P.S.,Savithri, H.S.,Murthy, M.R.N.; Crystal structure of Salmonella typhimurium 2-methylisocitrate lyase (PrpB) and its complex with pyruvate and Mg(2+); Biochem.Biophys.Res.Commun., 311:193-201, 2003; PubMed: 14575713; DOI: 10.1016/j.bbrc.2003.09.193

Experimental method

X-RAY DIFFRACTION (2.3 Å)