5ICY
| Cetuximab Fab in complex with linear meditope | 分子名称: | Cetuximab Fab heavy chain, Cetuximab Fab light chain, Meditope, ... | 著者 | Bzymek, K.P, Williams, J.C. | 登録日 | 2016-02-23 | 公開日 | 2016-06-15 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Cyclization strategies of meditopes: affinity and diffraction studies of meditope-Fab complexes. Acta Crystallogr F Struct Biol Commun, 72, 2016
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5I1D
| CRYSTAL STRUCTURE OF HUMAN GERMLINE ANTIBODY IGHV3-23/IGKV4-1 | 分子名称: | FAB HEAVY CHAIN, FAB LIGHT CHAIN, SULFATE ION | 著者 | Teplyakov, A, Obmolova, G, Malia, T, Luo, J, Gilliland, G. | 登録日 | 2016-02-05 | 公開日 | 2016-02-24 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structural diversity in a human antibody germline library. Mabs, 8, 2016
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5I5P
| Crystal structure of a marine metagenome TRAP solute binding protein specific for aromatic acid ligands (Sorcerer II Global Ocean Sampling Expedition, unidentified microbe, locus tag GOS_1523157) in complex with co-purified 4-hydroxybenzoate | 分子名称: | BROMIDE ION, DI(HYDROXYETHYL)ETHER, P-HYDROXYBENZOIC ACID, ... | 著者 | Vetting, M.W, Al Obaidi, N.F, Hogle, S.L, Dupont, C.L, Almo, S.C. | 登録日 | 2016-02-15 | 公開日 | 2017-01-18 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Crystal structure of a marine metagenome TRAP solute binding protein specific for aromatic acid ligands (Sorcerer II Global Ocean Sampling Expedition, unidentified microbe, locus tag GOS_1523157) in complex with co-purified 4-hydroxybenzoate To Be Published
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5ICZ
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7B4D
| Structural basis of reactivation of oncogenic p53 mutants by a small molecule: methylene quinuclidinone (MQ). Human p53DBD-R273C/S240R double mutant bound to DNA and MQ: R273C/S240R-DNA-MQ | 分子名称: | (2~{R})-2-methyl-1-azabicyclo[2.2.2]octan-3-one, (2~{S})-2-methyl-1-azabicyclo[2.2.2]octan-3-one, Cellular tumor antigen p53, ... | 著者 | Rozenberg, H, Diskin-Posner, Y, Degtjarik, O, Shakked, Z. | 登録日 | 2020-12-02 | 公開日 | 2021-12-08 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Structural basis of reactivation of oncogenic p53 mutants by a small molecule: methylene quinuclidinone (MQ). Nat Commun, 12, 2021
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7B4G
| Structural basis of reactivation of oncogenic p53 mutants by a small molecule: methylene quinuclidinone (MQ). Human p53DBD-R282W mutant bound to DNA: R282W-MQ (II) | 分子名称: | 1,2-ETHANEDIOL, Cellular tumor antigen p53, DI(HYDROXYETHYL)ETHER, ... | 著者 | Degtjarik, O, Rozenberg, H, Shakked, Z. | 登録日 | 2020-12-02 | 公開日 | 2021-12-08 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.86 Å) | 主引用文献 | Structural basis of reactivation of oncogenic p53 mutants by a small molecule: methylene quinuclidinone (MQ). Nat Commun, 12, 2021
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7B4F
| Structural basis of reactivation of oncogenic p53 mutants by a small molecule: methylene quinuclidinone (MQ). Human p53DBD-R282W mutant bound to DNA: R282W-MQ (I) | 分子名称: | Cellular tumor antigen p53, DNA target, FORMIC ACID, ... | 著者 | Rozenberg, H, Degtjarik, O, Shakked, Z. | 登録日 | 2020-12-02 | 公開日 | 2021-12-08 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.78 Å) | 主引用文献 | Structural basis of reactivation of oncogenic p53 mutants by a small molecule: methylene quinuclidinone (MQ). Nat Commun, 12, 2021
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5ITV
| Crystal structure of Bacillus subtilis BacC Dihydroanticapsin 7-dehydrogenase in complex with NADH | 分子名称: | 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, Dihydroanticapsin 7-dehydrogenase | 著者 | Perinbam, K, Balaram, H, Row, T.N.G, Gopal, B. | 登録日 | 2016-03-17 | 公開日 | 2017-02-22 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.26 Å) | 主引用文献 | Probing the influence of non-covalent contact networks identified by charge density analysis on the oxidoreductase BacC. Protein Eng. Des. Sel., 30, 2017
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7TX5
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7TX3
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5J0R
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5J0X
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7TX4
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7U9C
| Crystal Structure of the wild type Escherichia coli Pyridoxal 5'-phosphate homeostasis protein (YGGS) | 分子名称: | PHOSPHATE ION, PYRIDOXAL-5'-PHOSPHATE, Pyridoxal phosphate homeostasis protein | 著者 | Donkor, A.K, Ghatge, M.S, Safo, M.K, Musayev, F.N. | 登録日 | 2022-03-10 | 公開日 | 2022-03-23 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Characterization of the Escherichia coli pyridoxal 5'-phosphate homeostasis protein (YggS): Role of lysine residues in PLP binding and protein stability. Protein Sci., 31, 2022
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3J7R
| Structure of the translating mammalian ribosome-Sec61 complex | 分子名称: | 18S ribosomal RNA, 28S ribosomal RNA, 5.8S ribosomal RNA, ... | 著者 | Voorhees, R.M, Fernandez, I.S, Scheres, S.H.W, Hegde, R.S. | 登録日 | 2014-08-01 | 公開日 | 2014-09-03 | 最終更新日 | 2019-10-30 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Structure of the Mammalian ribosome-sec61 complex to 3.4 a resolution. Cell(Cambridge,Mass.), 157, 2014
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3J8A
| Structure of the F-actin-tropomyosin complex | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | 著者 | von der Ecken, J, Mueller, M, Lehman, W, Manstein, J.M, Penczek, A.P, Raunser, S. | 登録日 | 2014-10-08 | 公開日 | 2014-12-10 | 最終更新日 | 2018-07-18 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Structure of the F-actin--tropomyosin complex. Nature, 519, 2015
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7U9H
| Crystal Structure of Escherichia coli apo Pyridoxal 5'-phosphate homeostasis protein (YGGS) | 分子名称: | Pyridoxal phosphate homeostasis protein, SULFATE ION | 著者 | Donkor, A.K, Ghatge, M.S, Musayev, F.N, Safo, M.K. | 登録日 | 2022-03-10 | 公開日 | 2022-03-23 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Characterization of the Escherichia coli pyridoxal 5'-phosphate homeostasis protein (YggS): Role of lysine residues in PLP binding and protein stability. Protein Sci., 31, 2022
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3WEF
| Crystal structure of the human squalene synthase in complex with farnesyl thiopyrophosphate | 分子名称: | S-[(2E,6E)-3,7,11-TRIMETHYLDODECA-2,6,10-TRIENYL] TRIHYDROGEN THIODIPHOSPHATE, Squalene synthase | 著者 | Liu, C.I, Jeng, W.Y, Wang, A.H.J. | 登録日 | 2013-07-07 | 公開日 | 2014-02-12 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | Structural insights into the catalytic mechanism of human squalene synthase. Acta Crystallogr.,Sect.D, 70, 2014
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5J0W
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4XGI
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5J2K
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4XFK
| Crystal structure of Leucine-, Isoleucine-, Valine-, Threonine-, and Alanine-binding protein from Brucella ovis | 分子名称: | ACETATE ION, Putative branched chain amino acid ABC transporter, periplasmic amino acid-binding protein, ... | 著者 | Seattle Structural Genomics Center for Infectious Disease (SSGCID) | 登録日 | 2014-12-27 | 公開日 | 2015-03-11 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | 主引用文献 | Crystal structure of Leucine-, Isoleucine-, Valine-, Threonine-, and Alanine-binding protein from Brucella ovis to be published
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3K5K
| Discovery of a 2,4-Diamino-7-aminoalkoxy-quinazoline as a Potent Inhibitor of Histone Lysine Methyltransferase, G9a | 分子名称: | 7-[3-(dimethylamino)propoxy]-6-methoxy-2-(4-methyl-1,4-diazepan-1-yl)-N-(1-methylpiperidin-4-yl)quinazolin-4-amine, CHLORIDE ION, Histone-lysine N-methyltransferase, ... | 著者 | Dong, A, Wasney, G.A, Liu, F, Chen, X, Allali-Hassani, A, Senisterra, G, Chau, I, Bountra, C, Weigelt, J, Edwards, A.M, Arrowsmith, C.H, Frye, S.V, Bochkarev, A, Brown, P.J, Jin, J, Vedadi, M, Structural Genomics Consortium (SGC) | 登録日 | 2009-10-07 | 公開日 | 2009-11-10 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Discovery of a 2,4-diamino-7-aminoalkoxyquinazoline as a potent and selective inhibitor of histone lysine methyltransferase G9a. J.Med.Chem., 52, 2009
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5J2A
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5J2F
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