PDB: 97138 件ウェブページステータス検索Chemie searchBIRD

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6VYG	Cryo-EM structure of Plasmodium vivax hexokinase (Closed state) 分子名称: Phosphotransferase 著者 Srivastava, S.S, Darling, J.E, Suryadi, J, Morris, J.C, Drew, M.E, Subramaniam, S. 登録日 2020-02-26 公開日 2020-05-06 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 Plasmodium vivax and human hexokinases share similar active sites but display distinct quaternary architectures Iucrj, 7, 2020
6W5G	Class D beta-lactamase BAT-2 分子名称: 1,2-ETHANEDIOL, BAT-2 beta-lactamase 著者 Smith, C.A, Vakulenko, S.B, Stewart, N.K, Toth, M. 登録日 2020-03-13 公開日 2020-06-24 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.451 Å) 主引用文献 A surface loop modulates activity of the Bacillus class D beta-lactamases. J.Struct.Biol., 211, 2020
1QXR	Crystal structure of phosphoglucose isomerase from Pyrococcus furiosus in complex with 5-phosphoarabinonate 分子名称: 5-PHOSPHOARABINONIC ACID, Glucose-6-phosphate isomerase, NICKEL (II) ION 著者 Swan, M.K, Solomons, J.T.G, Beeson, C.C, Hansen, P, Schonheit, P, Davies, C. 登録日 2003-09-08 公開日 2003-12-09 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Structural evidence for a hydride transfer mechanism of catalysis in phosphoglucose isomerase from Pyrococcus furiosus J.Biol.Chem., 278, 2003
1QY4	Crystal structure of phosphoglucose isomerase from Pyrococcus furiosus in complex with gluconate 6-phosphate 分子名称: 6-PHOSPHOGLUCONIC ACID, Glucose-6-phosphate isomerase, NICKEL (II) ION 著者 Swan, M.K, Solomons, J.T.G, Beeson, C.C, Hansen, T, Schonheit, P, Davies, C. 登録日 2003-09-09 公開日 2003-12-09 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structural evidence for a hydride transfer mechanism of catalysis in phosphoglucose isomerase from Pyrococcus furiosus J.Biol.Chem., 278, 2003
3BWZ	Crystal structure of the type II cohesin module from the cellulosome of Acetivibrio cellulolyticus with an extended linker conformation 分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, Cellulosomal scaffoldin adaptor protein B, ... 著者 Noach, I, Lamed, R, Shimon, L.J.W, Bayer, E, Frolow, F. 登録日 2008-01-10 公開日 2009-01-13 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.2 Å) 主引用文献 Intermodular linker flexibility revealed from crystal structures of adjacent cellulosomal cohesins of Acetivibrio cellulolyticus. J.Mol.Biol., 391, 2009
6VR7	Structure of a pseudomurein peptide ligase type C from Methanothermus fervidus 分子名称: ACETOACETIC ACID, GLYCEROL, Mur ligase middle domain protein, ... 著者 Carbone, V, Schofield, L.R, Sutherland-Smith, A.J, Ronimus, R.S, Subedi, B.P. 登録日 2020-02-06 公開日 2021-02-10 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Archaeal pseudomurein and bacterial murein cell wall biosynthesis share a common evolutionary ancestry FEMS Microbes, 2, 2021
2GU2	Crystal Structure of an Aspartoacylase from Rattus norvegicus 分子名称: Aspa protein, SULFATE ION, ZINC ION 著者 Bitto, E, Wesenberg, G.E, Phillips Jr, G.N, Bingman, C.A, Center for Eukaryotic Structural Genomics (CESG) 登録日 2006-04-28 公開日 2006-06-20 最終更新日 2022-12-21 実験手法 X-RAY DIFFRACTION (1.805 Å) 主引用文献 Structure of aspartoacylase, the brain enzyme impaired in Canavan disease. Proc.Natl.Acad.Sci.Usa, 104, 2007
6VR3	Aminoglycoside N-2'-Acetyltransferase-Ia [AAC(2')-Ia] in complex with acetylated-netilmicin and CoA 分子名称: Aminoglycoside 2'-N-acetyltransferase, COENZYME A, N-[(2S,3R)-2-{[(1R,2S,3S,4R,6S)-6-amino-3-{[3-deoxy-4-C-methyl-3-(methylamino)-beta-L-lyxopyranosyl]oxy}-4-(ethylamino) -2-hydroxycyclohexyl]oxy}-6-(aminomethyl)-3,4-dihydro-2H-pyran-3-yl]acetamide 著者 Bassenden, A.V, Berghuis, A.M. 登録日 2020-02-06 公開日 2021-06-02 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structural and phylogenetic analyses of resistance to next-generation aminoglycosides conferred by AAC(2') enzymes. Sci Rep, 11, 2021
6VR2	Aminoglycoside N-2'-Acetyltransferase-Ia [AAC(2')-Ia] in complex with acetylated-tobramycin and CoA 分子名称: (1S,2S,3R,4S,6R)-3-{[2-(acetylamino)-6-amino-2,3,6-trideoxy-alpha-D-ribo-hexopyranosyl]oxy}-4,6-diamino-2-hydroxycycloh exyl 3-amino-3-deoxy-alpha-D-glucopyranoside, ACETATE ION, Aminoglycoside 2'-N-acetyltransferase, ... 著者 Bassenden, A.V, Berghuis, A.M. 登録日 2020-02-06 公開日 2021-06-02 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.77 Å) 主引用文献 Structural and phylogenetic analyses of resistance to next-generation aminoglycosides conferred by AAC(2') enzymes. Sci Rep, 11, 2021
6VTA	Aminoglycoside N-2'-Acetyltransferase-Ia [AAC(2')-Ia] in complex with amikacin and acetyl-CoA 分子名称: (2S)-N-[(1R,2S,3S,4R,5S)-4-[(2R,3R,4S,5S,6R)-6-(aminomethyl)-3,4,5-tris(oxidanyl)oxan-2-yl]oxy-5-azanyl-2-[(2S,3R,4S,5S ,6R)-4-azanyl-6-(hydroxymethyl)-3,5-bis(oxidanyl)oxan-2-yl]oxy-3-oxidanyl-cyclohexyl]-4-azanyl-2-oxidanyl-butanamide, ACETYL COENZYME *A, Aminoglycoside 2'-N-acetyltransferase 著者 Bassenden, A.V, Berghuis, A.M. 登録日 2020-02-12 公開日 2021-06-02 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.42 Å) 主引用文献 Structural and phylogenetic analyses of resistance to next-generation aminoglycosides conferred by AAC(2') enzymes. Sci Rep, 11, 2021
1CQU	SOLUTION STRUCTURE OF THE N-TERMINAL DOMAIN OF RIBOSOMAL PROTEIN L9 分子名称: 50S RIBOSOMAL PROTEIN L9 著者 Hua, Y, Kuhlman, B, Hoffman, D, Raleigh, D.P. 登録日 1999-08-11 公開日 2002-04-27 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 Effects of varying the local propensity to form secondary structure on the stability and folding kinetics of a rapid folding mixed alpha/beta protein: characterization of a truncation mutant of the N-terminal domain of the ribosomal protein L9. J.Mol.Biol., 289, 1999
7FCD	Structure of the SARS-CoV-2 A372T spike glycoprotein (open) 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein 著者 Wang, X, Zhang, S. 登録日 2021-07-14 公開日 2022-01-26 最終更新日 2022-03-16 実験手法 ELECTRON MICROSCOPY (3.9 Å) 主引用文献 Loss of Spike N370 glycosylation as an important evolutionary event for the enhanced infectivity of SARS-CoV-2. Cell Res., 32, 2022
7C1M	Complex structure of tyrosinated alpha-tubulin carboxy-terminal peptide and A1aY1 binder 分子名称: Carboxy-terminal peptide from tyrosinated alpha-tubulin, Nanobody binder from SSO7d library 著者 Kesarwani, S, Reddy, P.P, Sirajuddin, M, Das, R. 登録日 2020-05-05 公開日 2020-09-02 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Genetically encoded live-cell sensor for tyrosinated microtubules. J.Cell Biol., 219, 2020
7FCE	Structure of the SARS-CoV-2 A372T spike glycoprotein (closed) 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein 著者 Wang, X, Zhang, S. 登録日 2021-07-14 公開日 2022-01-26 最終更新日 2022-03-16 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Loss of Spike N370 glycosylation as an important evolutionary event for the enhanced infectivity of SARS-CoV-2. Cell Res., 32, 2022
3D7M	Crystal Structure of the G Protein Fast-Exchange Double Mutant I56C/Q333C 分子名称: GUANOSINE-5'-DIPHOSPHATE, Guanine nucleotide-binding protein G(i), alpha-1 subunit, ... 著者 Funk, M.A, Preininger, A.M, Oldham, W.M, Meier, S.M, Hamm, H.E, Iverson, T.M. 登録日 2008-05-21 公開日 2009-03-03 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Helix dipole movement and conformational variability contribute to allosteric GDP release in Galphai subunits. Biochemistry, 48, 2009
3D00	Crystal structure of a tungsten formylmethanofuran dehydrogenase subunit e (fmde)-like protein (syn_00638) from syntrophus aciditrophicus at 1.90 A resolution 分子名称: CHLORIDE ION, Tungsten formylmethanofuran dehydrogenase subunit E, ZINC ION 著者 Joint Center for Structural Genomics (JCSG) 登録日 2008-04-30 公開日 2008-05-20 最終更新日 2023-02-01 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structures of three members of Pfam PF02663 (FmdE) implicated in microbial methanogenesis reveal a conserved alpha+beta core domain and an auxiliary C-terminal treble-clef zinc finger. Acta Crystallogr.,Sect.F, 66, 2010
3P6I	Crystal structure of Symfoil-4T Permutation #2: de novo designed beta-trefoil architecture with symmetric primary structure 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, SULFATE ION, de novo designed beta-trefoil architecture with symmetric primary structure 著者 Blaber, M, Lee, J. 登録日 2010-10-11 公開日 2011-10-12 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.32 Å) 主引用文献 Permutations study of de novo designed symmetric beta-trefoil architecture To be Published
3P6J	Crystal structure of Symfoil-4T Permutation #3: de novo designed beta-trefoil architecture with symmetric primary structure 分子名称: de novo designed beta-trefoil architecture with symmetric primary structure 著者 Blaber, M, Lee, J. 登録日 2010-10-11 公開日 2011-10-12 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.35 Å) 主引用文献 Permutations study of de novo designed symmetric beta-trefoil architecture To be Published
1N8K	Horse Liver Alcohol Dehydrogenase Val292Thr Mutant Complexed to NAD+ and Pyrazole 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, Alcohol Dehydrogenase E chain, NICOTINAMIDE-ADENINE-DINUCLEOTIDE (ACIDIC FORM), ... 著者 Rubach, J.K, Plapp, B.V. 登録日 2002-11-21 公開日 2003-02-04 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (1.13 Å) 主引用文献 Amino Acid Residues in the Nicotinamide Binding Site Contribute to Catalysis by Horse Liver Alcohol Dehydrogenase Biochemistry, 42, 2003
1N92	Horse Liver Alcohol Dehydrogenase Complexed with NAD+ and 4-Iodopyrazole 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 4-IODOPYRAZOLE, Alcohol Dehydrogenase E chain, ... 著者 Rubach, J.K, Plapp, B.V. 登録日 2002-11-21 公開日 2003-02-04 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (1.47 Å) 主引用文献 Amino Acid Residues in the Nicotinamide Binding Site Contribute to Catalysis by Horse Liver Alcohol Dehydrogenase Biochemistry, 42, 2003
3CPC	Crystal structure of the VEGFR2 kinase domain in complex with a pyridone inhibitor 分子名称: 3-(2-aminoquinazolin-6-yl)-4-methyl-1-[3-(trifluoromethyl)phenyl]pyridin-2(1H)-one, Vascular endothelial growth factor receptor 2 著者 Whittington, D.A, Long, A.M, Rose, P, Gu, Y, Zhao, H. 登録日 2008-03-31 公開日 2008-06-17 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Discovery of Aryl Aminoquinazoline Pyridones as Potent, Selective, and Orally Efficacious Inhibitors of Receptor Tyrosine Kinase c-Kit. J.Med.Chem., 51, 2008
7FJH	LecA from Pseudomonas aeruginosa in complex with 4-Phenylbutyryl hydroxamic acid (CAS: 32153-46-1) 分子名称: CALCIUM ION, N-oxidanyl-4-phenyl-butanamide, PA-I galactophilic lectin 著者 Shanina, S, Kuhaudomlarp, S, Siebs, E, Fuchsberger, F, Denis, M, da Silva Figueiredo Celstino Gomes, P, Clausen, M.H, Seeberger, P.H, Rognan, D, Titz, A, Imberty, A, Rademacher, C. 登録日 2021-08-04 公開日 2022-06-08 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.79 Å) 主引用文献 Targeting undruggable carbohydrate recognition sites through focused fragment library design. Commun Chem, 5, 2022
6WO1	Hybrid acetohydroxyacid synthase complex structure with Cryptococcus neoformans AHAS catalytic subunit and Saccharomyces cerevisiae AHAS regulatory subunit 分子名称: 2-methylpyrimidin-4-amine, Acetohydroxyacid synthase catalytic subunit, Acetohydroxyacid synthase regulatory subunit, ... 著者 Guddat, L.W, Lonhienne, T. 登録日 2020-04-23 公開日 2020-07-15 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (3.3 Å) 主引用文献 Structures of fungal and plant acetohydroxyacid synthases. Nature, 586, 2020
8AR7	Bovine glutamate dehydrogenase in ternary complex with the allosteric activators ADP and leucine 分子名称: ADENOSINE-5'-DIPHOSPHATE, Glutamate dehydrogenase (NAD(P)(+)), LEUCINE, ... 著者 Aleshin, V.A, Bellinzoni, M. 登録日 2022-08-15 公開日 2022-10-05 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.448 Å) 主引用文献 Structural Basis for the Binding of Allosteric Activators Leucine and ADP to Mammalian Glutamate Dehydrogenase. Int J Mol Sci, 23, 2022
6DF3	Crystal structure of ternary complex of IL-24 with soluble receptors IL-22RA and IL-20RB 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, ... 著者 Lubkowski, J, Wlodawer, A. 登録日 2018-05-14 公開日 2018-08-15 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Crystal Structure of the Labile Complex of IL-24 with the Extracellular Domains of IL-22R1 and IL-20R2. J. Immunol., 201, 2018

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