PDB: 66478 件ウェブページステータス検索Chemie searchBIRD

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7L5H	The external aldimine form of the wild-type Salmonella typhimurium Tryptophan Synthase at 1.80 Angstrom resolution with cesium ion at the metal coordination site 分子名称: (E)-N-({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methylidene)-L-serine, 1,2-ETHANEDIOL, CESIUM ION, ... 著者 Hilario, E, Dunn, M.F, Mueller, L.J. 登録日 2020-12-22 公開日 2021-12-29 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 The external aldimine form of the wild-type Salmonella typhimurium Tryptophan Synthase at 1.80 Angstrom resolution with cesium ion at the metal coordination site. To be Published
3CD8	X-ray Structure of c-Met with triazolopyridazine Inhibitor. 分子名称: 7-methoxy-4-[(6-phenyl[1,2,4]triazolo[4,3-b]pyridazin-3-yl)methoxy]quinoline, Hepatocyte growth factor receptor 著者 Bellon, S.F, Albrecht, B.K, Harmange, J.-C, Bauer, D, Choquette, D, Dussault, I. 登録日 2008-02-26 公開日 2008-04-29 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Discovery and Optimization of Triazolopyridazines as Potent and Selective Inhibitors of the c-Met Kinase. J.Med.Chem., 51, 2008
3PMT	Crystal structure of the Tudor domain of human Tudor domain-containing protein 3 分子名称: TETRAETHYLENE GLYCOL, Tudor domain-containing protein 3 著者 Lam, R, Bian, C.B, Guo, Y.H, Xu, C, Kania, J, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Min, J, Structural Genomics Consortium (SGC) 登録日 2010-11-18 公開日 2010-12-01 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Crystal Structure of TDRD3 and Methyl-Arginine Binding Characterization of TDRD3, SMN and SPF30. Plos One, 7, 2012
3NEA	Crystal Structure of Peptidyl-tRNA hydrolase from Francisella tularensis 分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, Peptidyl-tRNA hydrolase 著者 Lam, R, McGrath, T.E, Romanov, V, Gothe, S.A, Peddi, S.R, Razumova, E, Lipman, R.S, Branstrom, A.A, Chirgadze, N.Y. 登録日 2010-06-08 公開日 2011-06-15 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Structure of Francisella tularensis peptidyl-tRNA hydrolase. Acta Crystallogr.,Sect.F, 67, 2011
3PGG	Crystal structure of cryptosporidium parvum u6 snrna-associated sm-like protein lsm5 分子名称: U6 snRNA-associated Sm-like protein LSm5. SM domain 著者 Dong, A, Gao, M, Zhao, Y, Lew, J, Wasney, G.A, Kozieradzki, I, Vedadi, M, Edwards, A, Arrowsmith, C, Weigelt, J, Sundstrom, M, Bochkarev, A, Hui, R, Artz, J, Structural Genomics Consortium (SGC) 登録日 2010-11-01 公開日 2011-02-02 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.14 Å) 主引用文献 Genome-Scale Protein Expression and Structural Biology of Plasmodium Falciparum and Related Apicomplexan Organisms. Mol.Biochem.Parasitol., 151, 2007
7MW7	Crystal structure of P1G mutant of D-dopachrome tautomerase 分子名称: D-dopachrome decarboxylase, SODIUM ION, SULFATE ION 著者 Manjula, R, Murphy, E.L, Murphy, J.W, Lolis, E. 登録日 2021-05-15 公開日 2021-08-18 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.1 Å) 主引用文献 A structurally preserved allosteric site in the MIF superfamily affects enzymatic activity and CD74 activation in D-dopachrome tautomerase. J.Biol.Chem., 297, 2021
4TOY	Structure of 35O22 Fab, a HIV-1 neutralizing antibody 分子名称: 35O22 Fab Heavy chain, 35O22 Fab Light chain 著者 Pancera, M, Kwong, P.D. 登録日 2014-06-06 公開日 2014-09-03 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.551 Å) 主引用文献 Broad and potent HIV-1 neutralization by a human antibody that binds the gp41-gp120 interface. Nature, 515, 2014
7MRV	F100A mutant structure of MIF2 (D-DT) 分子名称: D-dopachrome decarboxylase, SULFATE ION 著者 Murphy, E.L, Manjula, R, Murphy, J.W, Lolis, E. 登録日 2021-05-09 公開日 2021-08-18 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.57 Å) 主引用文献 A structurally preserved allosteric site in the MIF superfamily affects enzymatic activity and CD74 activation in D-dopachrome tautomerase. J.Biol.Chem., 297, 2021
2RDG	Crystal structure of Staphylococcal Superantigen-Like protein 11 in complex with Sialyl Lewis X 分子名称: CITRIC ACID, N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-4)-[alpha-L-fucopyranose-(1-3)]2-acetamido-2-deoxy-alpha-D-glucopyranose, POTASSIUM ION, ... 著者 Chung, M.C, Wines, B.D, Baker, H, Langley, R.J, Baker, E.N, Fraser, J.D. 登録日 2007-09-24 公開日 2007-12-18 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 The crystal structure of staphylococcal superantigen-like protein 11 in complex with sialyl Lewis X reveals the mechanism for cell binding and immune inhibition Mol.Microbiol., 66, 2007
5W56	Structure of Apo AztC 分子名称: GLYCEROL, Periplasmic solute binding protein, SODIUM ION 著者 Avalos, D, Yukl, E.T. 登録日 2017-06-14 公開日 2017-09-20 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.03 Å) 主引用文献 Mechanisms of zinc binding to the solute-binding protein AztC and transfer from the metallochaperone AztD. J. Biol. Chem., 292, 2017
8GQG	Crystal structure of Thioloase from Pseudomonas aeruginosa PAO1 分子名称: Thiolase 著者 Hong, J, Son, H.F, Kim, K.J. 登録日 2022-08-30 公開日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structure of thiolase from Pseudomonas aeruginosa PAO1 To Be Published
2R5N	Crystal structure of transketolase from Escherichia coli in noncovalent complex with acceptor aldose ribose 5-phosphate 分子名称: 1,2-ETHANEDIOL, 5-O-phosphono-beta-D-ribofuranose, CALCIUM ION, ... 著者 Parthier, C, Asztalos, P, Wille, G, Tittmann, K. 登録日 2007-09-04 公開日 2007-11-06 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Strain and Near Attack Conformers in Enzymic Thiamin Catalysis: X-ray Crystallographic Snapshots of Bacterial Transketolase in Covalent Complex with Donor Ketoses Xylulose 5-phosphate and Fructose 6-phosphate, and in Noncovalent Complex with Acceptor Aldose Ribose 5-phosphate. Biochemistry, 46, 2007
4OB8	Crystal structure of a novel thermostable esterase from Pseudomonas putida ECU1011 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, Alpha/beta hydrolase fold-3 domain protein, DI(HYDROXYETHYL)ETHER 著者 Dou, S, Kong, X.D, Ma, B.D, Xu, J.H, Zhou, J.H. 登録日 2014-01-07 公開日 2014-07-23 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.801 Å) 主引用文献 Crystal structures of Pseudomonas putida esterase reveal the functional role of residues 187 and 287 in substrate binding and chiral recognition Biochem.Biophys.Res.Commun., 446, 2014
5E2V	Anti-TAU AT8 FAB with doubly phosphorylated TAU peptide 分子名称: AT8 HEAVY CHAIN, AT8 LIGHT CHAIN, GLYCEROL, ... 著者 Malia, T, Teplyakov, A. 登録日 2015-10-01 公開日 2016-02-24 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.64 Å) 主引用文献 Epitope mapping and structural basis for the recognition of phosphorylated tau by the anti-tau antibody AT8. Proteins, 84, 2016
5WBB	Peroxide Activation Regulated by Hydrogen Bonds within Artificial Cu Proteins - S112A 分子名称: COPPER (II) ION, GLYCEROL, SULFATE ION, ... 著者 Mann, S.I, Heinisch, T, Ward, T.R, Borovik, A.S. 登録日 2017-06-28 公開日 2017-11-22 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Peroxide Activation Regulated by Hydrogen Bonds within Artificial Cu Proteins. J. Am. Chem. Soc., 139, 2017
5WBL	Crystal structure of the Arabidopsis thaliana Raptor in complex with the TOS peptide of human PRAS40 分子名称: Proline-rich AKT1 substrate 1, Regulatory-associated protein of TOR 1 著者 Pavletich, N.P, Jiang, X. 登録日 2017-06-29 公開日 2017-12-20 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (3.35 Å) 主引用文献 Mechanisms of mTORC1 activation by RHEB and inhibition by PRAS40. Nature, 552, 2017
5W90	FEZ-1 metallo-beta-lactamase from Legionella gormanii modelled with unknown ligand 分子名称: FEZ-1 protein, GLYCEROL, SULFATE ION, ... 著者 Garcia-Saez, I, Mercuri, P.S, Kahn, R, Shabalin, I.G, Raczynska, J.E, Jaskolski, M, Minor, W, Papamicael, C, Frere, J.M, Galleni, M, Dideberg, O. 登録日 2017-06-22 公開日 2018-06-20 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.78 Å) 主引用文献 Three-dimensional structure of FEZ-1, a monomeric subclass B3 metallo-beta-lactamase from Fluoribacter gormanii, in native form and in complex with D-captopril. J. Mol. Biol., 325, 2003
4OB7	Crystal structure of esterase rPPE mutant W187H 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, Alpha/beta hydrolase fold-3 domain protein, DI(HYDROXYETHYL)ETHER 著者 Dou, S, Kong, X.D, Ma, B.D, Xu, J.H, Zhou, J.H. 登録日 2014-01-07 公開日 2014-07-23 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Crystal structures of Pseudomonas putida esterase reveal the functional role of residues 187 and 287 in substrate binding and chiral recognition Biochem.Biophys.Res.Commun., 446, 2014
5W97	Crystal Structure of CO-bound Cytochrome c Oxidase determined by Serial Femtosecond X-Ray Crystallography at Room Temperature 分子名称: (1R)-2-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL (11E)-OCTADEC-11-ENOATE, (1S)-2-{[(2-AMINOETHOXY)(HYDROXY)PHOSPHORYL]OXY}-1-[(STEAROYLOXY)METHYL]ETHYL (5E,8E,11E,14E)-ICOSA-5,8,11,14-TETRAENOATE, (7R,17E,20E)-4-HYDROXY-N,N,N-TRIMETHYL-9-OXO-7-[(PALMITOYLOXY)METHYL]-3,5,8-TRIOXA-4-PHOSPHAHEXACOSA-17,20-DIEN-1-AMINIUM 4-OXIDE, ... 著者 Rousseau, D.L, Yeh, S.-R, Ishigami, I, Zatsepin, N.A, Grant, T.D, Fromme, P, Fromme, R. 登録日 2017-06-22 公開日 2017-08-09 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Crystal structure of CO-bound cytochrome c oxidase determined by serial femtosecond X-ray crystallography at room temperature. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5WAB	Crystal Structure of Bifidobacterium adolescentis GH3 beta-glucosidase 分子名称: GLYCEROL, Putative beta-glucosidase 著者 Florindo, R.N, Nascimento, A.S, Polikarpov, I. 登録日 2017-06-26 公開日 2018-04-04 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.45 Å) 主引用文献 Structural and biochemical characterization of a GH3 beta-glucosidase from the probiotic bacteria Bifidobacterium adolescentis. Biochimie, 148, 2018
5WBK	Crystal structure of the arabidopsis thaliana Raptor in complex with the TOS peptide of human S6K1 分子名称: Regulatory-associated protein of TOR 1, Ribosomal protein S6 kinase beta-1 著者 Pavletich, N.P, Jiang, X. 登録日 2017-06-29 公開日 2017-12-20 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (3.11 Å) 主引用文献 Mechanisms of mTORC1 activation by RHEB and inhibition by PRAS40. Nature, 552, 2017
5WJ9	Human TRPML1 channel structure in agonist-bound open conformation 分子名称: 2-{2-oxo-2-[(4S)-2,2,4-trimethyl-3,4-dihydroquinolin-1(2H)-yl]ethyl}-1H-isoindole-1,3(2H)-dione, Mucolipin-1 著者 Schmiege, P, Li, X. 登録日 2017-07-21 公開日 2017-10-18 最終更新日 2019-12-18 実験手法 ELECTRON MICROSCOPY (3.49 Å) 主引用文献 Human TRPML1 channel structures in open and closed conformations. Nature, 550, 2017
5WLL	De Novo Design of Polynuclear Transition Metal Clusters in Helix Bundles-4DH1 分子名称: GLYCEROL, Helical Bundle 4DH1, ZINC ION 著者 Zhang, S.-Q, Liu, L, DeGrado, W.F. 登録日 2017-07-27 公開日 2018-01-03 最終更新日 2020-01-01 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 De Novo Design of Tetranuclear Transition Metal Clusters Stabilized by Hydrogen-Bonded Networks in Helical Bundles. J. Am. Chem. Soc., 140, 2018
5WNM	Crystal structure of murine receptor-interacting protein 4 (Ripk4) D143N bound to tozasertib (VX-680) 分子名称: CHLORIDE ION, CYCLOPROPANECARBOXYLIC ACID {4-[4-(4-METHYL-PIPERAZIN-1-YL)-6-(5-METHYL-2H-PYRAZOL-3-YLAMINO)-PYRIMIDIN-2-YLSULFANYL]-PHENYL}-AMIDE, Receptor-interacting serine/threonine-protein kinase 4 著者 Huang, C.S, Hymowitz, S.G. 登録日 2017-08-01 公開日 2018-05-09 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Crystal Structure of Ripk4 Reveals Dimerization-Dependent Kinase Activity. Structure, 26, 2018
5WKD	Crystal structure of the segment, GNNQGSN, from the low complexity domain of TDP-43, residues 300-306 分子名称: TAR DNA-binding protein 43 著者 Guenther, E.L, Trinh, H, Sawaya, M.R, Cascio, D, Eisenberg, D.S. 登録日 2017-07-25 公開日 2018-04-18 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Atomic structures of TDP-43 LCD segments and insights into reversible or pathogenic aggregation. Nat. Struct. Mol. Biol., 25, 2018

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