7L5H
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3CD8
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![BU of 3cd8 by Molmil](/molmil-images/mine/3cd8) | X-ray Structure of c-Met with triazolopyridazine Inhibitor. | 分子名称: | 7-methoxy-4-[(6-phenyl[1,2,4]triazolo[4,3-b]pyridazin-3-yl)methoxy]quinoline, Hepatocyte growth factor receptor | 著者 | Bellon, S.F, Albrecht, B.K, Harmange, J.-C, Bauer, D, Choquette, D, Dussault, I. | 登録日 | 2008-02-26 | 公開日 | 2008-04-29 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Discovery and Optimization of Triazolopyridazines as Potent and Selective Inhibitors of the c-Met Kinase. J.Med.Chem., 51, 2008
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3PMT
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![BU of 3pmt by Molmil](/molmil-images/mine/3pmt) | Crystal structure of the Tudor domain of human Tudor domain-containing protein 3 | 分子名称: | TETRAETHYLENE GLYCOL, Tudor domain-containing protein 3 | 著者 | Lam, R, Bian, C.B, Guo, Y.H, Xu, C, Kania, J, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Min, J, Structural Genomics Consortium (SGC) | 登録日 | 2010-11-18 | 公開日 | 2010-12-01 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Crystal Structure of TDRD3 and Methyl-Arginine Binding Characterization of TDRD3, SMN and SPF30. Plos One, 7, 2012
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3NEA
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![BU of 3nea by Molmil](/molmil-images/mine/3nea) | Crystal Structure of Peptidyl-tRNA hydrolase from Francisella tularensis | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, Peptidyl-tRNA hydrolase | 著者 | Lam, R, McGrath, T.E, Romanov, V, Gothe, S.A, Peddi, S.R, Razumova, E, Lipman, R.S, Branstrom, A.A, Chirgadze, N.Y. | 登録日 | 2010-06-08 | 公開日 | 2011-06-15 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | Structure of Francisella tularensis peptidyl-tRNA hydrolase. Acta Crystallogr.,Sect.F, 67, 2011
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3PGG
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![BU of 3pgg by Molmil](/molmil-images/mine/3pgg) | Crystal structure of cryptosporidium parvum u6 snrna-associated sm-like protein lsm5 | 分子名称: | U6 snRNA-associated Sm-like protein LSm5. SM domain | 著者 | Dong, A, Gao, M, Zhao, Y, Lew, J, Wasney, G.A, Kozieradzki, I, Vedadi, M, Edwards, A, Arrowsmith, C, Weigelt, J, Sundstrom, M, Bochkarev, A, Hui, R, Artz, J, Structural Genomics Consortium (SGC) | 登録日 | 2010-11-01 | 公開日 | 2011-02-02 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.14 Å) | 主引用文献 | Genome-Scale Protein Expression and Structural Biology of Plasmodium Falciparum and Related Apicomplexan Organisms. Mol.Biochem.Parasitol., 151, 2007
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7MW7
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![BU of 7mw7 by Molmil](/molmil-images/mine/7mw7) | Crystal structure of P1G mutant of D-dopachrome tautomerase | 分子名称: | D-dopachrome decarboxylase, SODIUM ION, SULFATE ION | 著者 | Manjula, R, Murphy, E.L, Murphy, J.W, Lolis, E. | 登録日 | 2021-05-15 | 公開日 | 2021-08-18 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.1 Å) | 主引用文献 | A structurally preserved allosteric site in the MIF superfamily affects enzymatic activity and CD74 activation in D-dopachrome tautomerase. J.Biol.Chem., 297, 2021
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4TOY
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7MRV
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![BU of 7mrv by Molmil](/molmil-images/mine/7mrv) | F100A mutant structure of MIF2 (D-DT) | 分子名称: | D-dopachrome decarboxylase, SULFATE ION | 著者 | Murphy, E.L, Manjula, R, Murphy, J.W, Lolis, E. | 登録日 | 2021-05-09 | 公開日 | 2021-08-18 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.57 Å) | 主引用文献 | A structurally preserved allosteric site in the MIF superfamily affects enzymatic activity and CD74 activation in D-dopachrome tautomerase. J.Biol.Chem., 297, 2021
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2RDG
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![BU of 2rdg by Molmil](/molmil-images/mine/2rdg) | Crystal structure of Staphylococcal Superantigen-Like protein 11 in complex with Sialyl Lewis X | 分子名称: | CITRIC ACID, N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-4)-[alpha-L-fucopyranose-(1-3)]2-acetamido-2-deoxy-alpha-D-glucopyranose, POTASSIUM ION, ... | 著者 | Chung, M.C, Wines, B.D, Baker, H, Langley, R.J, Baker, E.N, Fraser, J.D. | 登録日 | 2007-09-24 | 公開日 | 2007-12-18 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | The crystal structure of staphylococcal superantigen-like protein 11 in complex with sialyl Lewis X reveals the mechanism for cell binding and immune inhibition Mol.Microbiol., 66, 2007
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5W56
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![BU of 5w56 by Molmil](/molmil-images/mine/5w56) | Structure of Apo AztC | 分子名称: | GLYCEROL, Periplasmic solute binding protein, SODIUM ION | 著者 | Avalos, D, Yukl, E.T. | 登録日 | 2017-06-14 | 公開日 | 2017-09-20 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.03 Å) | 主引用文献 | Mechanisms of zinc binding to the solute-binding protein AztC and transfer from the metallochaperone AztD. J. Biol. Chem., 292, 2017
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8GQG
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2R5N
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![BU of 2r5n by Molmil](/molmil-images/mine/2r5n) | Crystal structure of transketolase from Escherichia coli in noncovalent complex with acceptor aldose ribose 5-phosphate | 分子名称: | 1,2-ETHANEDIOL, 5-O-phosphono-beta-D-ribofuranose, CALCIUM ION, ... | 著者 | Parthier, C, Asztalos, P, Wille, G, Tittmann, K. | 登録日 | 2007-09-04 | 公開日 | 2007-11-06 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Strain and Near Attack Conformers in Enzymic Thiamin Catalysis: X-ray Crystallographic Snapshots of Bacterial Transketolase in Covalent Complex with Donor Ketoses Xylulose 5-phosphate and Fructose 6-phosphate, and in Noncovalent Complex with Acceptor Aldose Ribose 5-phosphate. Biochemistry, 46, 2007
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4OB8
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![BU of 4ob8 by Molmil](/molmil-images/mine/4ob8) | Crystal structure of a novel thermostable esterase from Pseudomonas putida ECU1011 | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, Alpha/beta hydrolase fold-3 domain protein, DI(HYDROXYETHYL)ETHER | 著者 | Dou, S, Kong, X.D, Ma, B.D, Xu, J.H, Zhou, J.H. | 登録日 | 2014-01-07 | 公開日 | 2014-07-23 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.801 Å) | 主引用文献 | Crystal structures of Pseudomonas putida esterase reveal the functional role of residues 187 and 287 in substrate binding and chiral recognition Biochem.Biophys.Res.Commun., 446, 2014
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5E2V
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5WBB
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![BU of 5wbb by Molmil](/molmil-images/mine/5wbb) | Peroxide Activation Regulated by Hydrogen Bonds within Artificial Cu Proteins - S112A | 分子名称: | COPPER (II) ION, GLYCEROL, SULFATE ION, ... | 著者 | Mann, S.I, Heinisch, T, Ward, T.R, Borovik, A.S. | 登録日 | 2017-06-28 | 公開日 | 2017-11-22 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Peroxide Activation Regulated by Hydrogen Bonds within Artificial Cu Proteins. J. Am. Chem. Soc., 139, 2017
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5WBL
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5W90
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![BU of 5w90 by Molmil](/molmil-images/mine/5w90) | FEZ-1 metallo-beta-lactamase from Legionella gormanii modelled with unknown ligand | 分子名称: | FEZ-1 protein, GLYCEROL, SULFATE ION, ... | 著者 | Garcia-Saez, I, Mercuri, P.S, Kahn, R, Shabalin, I.G, Raczynska, J.E, Jaskolski, M, Minor, W, Papamicael, C, Frere, J.M, Galleni, M, Dideberg, O. | 登録日 | 2017-06-22 | 公開日 | 2018-06-20 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.78 Å) | 主引用文献 | Three-dimensional structure of FEZ-1, a monomeric subclass B3 metallo-beta-lactamase from Fluoribacter gormanii, in native form and in complex with D-captopril. J. Mol. Biol., 325, 2003
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4OB7
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![BU of 4ob7 by Molmil](/molmil-images/mine/4ob7) | Crystal structure of esterase rPPE mutant W187H | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, Alpha/beta hydrolase fold-3 domain protein, DI(HYDROXYETHYL)ETHER | 著者 | Dou, S, Kong, X.D, Ma, B.D, Xu, J.H, Zhou, J.H. | 登録日 | 2014-01-07 | 公開日 | 2014-07-23 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Crystal structures of Pseudomonas putida esterase reveal the functional role of residues 187 and 287 in substrate binding and chiral recognition Biochem.Biophys.Res.Commun., 446, 2014
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5W97
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![BU of 5w97 by Molmil](/molmil-images/mine/5w97) | Crystal Structure of CO-bound Cytochrome c Oxidase determined by Serial Femtosecond X-Ray Crystallography at Room Temperature | 分子名称: | (1R)-2-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL (11E)-OCTADEC-11-ENOATE, (1S)-2-{[(2-AMINOETHOXY)(HYDROXY)PHOSPHORYL]OXY}-1-[(STEAROYLOXY)METHYL]ETHYL (5E,8E,11E,14E)-ICOSA-5,8,11,14-TETRAENOATE, (7R,17E,20E)-4-HYDROXY-N,N,N-TRIMETHYL-9-OXO-7-[(PALMITOYLOXY)METHYL]-3,5,8-TRIOXA-4-PHOSPHAHEXACOSA-17,20-DIEN-1-AMINIUM 4-OXIDE, ... | 著者 | Rousseau, D.L, Yeh, S.-R, Ishigami, I, Zatsepin, N.A, Grant, T.D, Fromme, P, Fromme, R. | 登録日 | 2017-06-22 | 公開日 | 2017-08-09 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Crystal structure of CO-bound cytochrome c oxidase determined by serial femtosecond X-ray crystallography at room temperature. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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5WAB
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5WBK
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5WJ9
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![BU of 5wj9 by Molmil](/molmil-images/mine/5wj9) | Human TRPML1 channel structure in agonist-bound open conformation | 分子名称: | 2-{2-oxo-2-[(4S)-2,2,4-trimethyl-3,4-dihydroquinolin-1(2H)-yl]ethyl}-1H-isoindole-1,3(2H)-dione, Mucolipin-1 | 著者 | Schmiege, P, Li, X. | 登録日 | 2017-07-21 | 公開日 | 2017-10-18 | 最終更新日 | 2019-12-18 | 実験手法 | ELECTRON MICROSCOPY (3.49 Å) | 主引用文献 | Human TRPML1 channel structures in open and closed conformations. Nature, 550, 2017
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5WLL
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5WNM
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5WKD
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![BU of 5wkd by Molmil](/molmil-images/mine/5wkd) | Crystal structure of the segment, GNNQGSN, from the low complexity domain of TDP-43, residues 300-306 | 分子名称: | TAR DNA-binding protein 43 | 著者 | Guenther, E.L, Trinh, H, Sawaya, M.R, Cascio, D, Eisenberg, D.S. | 登録日 | 2017-07-25 | 公開日 | 2018-04-18 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Atomic structures of TDP-43 LCD segments and insights into reversible or pathogenic aggregation. Nat. Struct. Mol. Biol., 25, 2018
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