7MW7

Crystal structure of P1G mutant of D-dopachrome tautomerase

Summary for 7MW7

Entry DOI	10.2210/pdb7mw7/pdb
Descriptor	D-dopachrome decarboxylase, SULFATE ION, SODIUM ION, ... (4 entities in total)
Functional Keywords	mitogen inhibitory factor 2, mutant, cytokine, lyase
Biological source	Homo sapiens (Human)
Total number of polymer chains	1
Total formula weight	12803.71
Authors	Manjula, R.,Murphy, E.L.,Murphy, J.W.,Lolis, E. (deposition date: 2021-05-15, release date: 2021-08-18, Last modification date: 2023-10-18)
Primary citation	Chen, E.,Reiss, K.,Shah, D.,Manjula, R.,Allen, B.,Murphy, E.L.,Murphy, J.W.,Batista, V.S.,Bhandari, V.,Lolis, E.J.,Lisi, G.P. A structurally preserved allosteric site in the MIF superfamily affects enzymatic activity and CD74 activation in D-dopachrome tautomerase. J.Biol.Chem., 297:101061-101061, 2021 Cited by PubMed: 34384784 DOI: 10.1016/j.jbc.2021.101061 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.1 Å)

Structure validation