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6X0J
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Structure of reduced SidA ornithine hydroxylase with the FAD "in" and complexed with NADP and L-ornithine
分子名称: DIHYDROFLAVINE-ADENINE DINUCLEOTIDE, L-ornithine, L-ornithine N(5)-monooxygenase, ...
著者Tanner, J.J, Campbell, A.C.
登録日2020-05-15
公開日2020-08-05
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.335 Å)
主引用文献Trapping conformational states of a flavin-dependent N -monooxygenase in crystallo reveals protein and flavin dynamics.
J.Biol.Chem., 295, 2020
2Z0W
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BU of 2z0w by Molmil
Crystal structure of the 2nd CAP-Gly domain in human Restin-like protein 2 reveals a swapped-dimer
分子名称: CAP-Gly domain-containing linker protein 4
著者Saito, K, Yoshikawa, S, Nishino, A, Murayama, K, Terada, T, Shirouzu, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2007-05-07
公開日2007-11-13
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal structure of the 2nd CAP-Gly domain in human Restin-like protein 2 reveals a swapped-dimer
To be Published
6WOM
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Crystal structure of Aspartyl-tRNA ligase from Elizabethkingia sp.
分子名称: Aspartate--tRNA ligase, SULFATE ION
著者Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2020-04-24
公開日2020-05-13
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Crystal structure of Aspartyl-tRNA ligase from Elizabethkingia sp.
TO BE PUBLISHED
2Z13
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BU of 2z13 by Molmil
Crystal structure of the N-terminal DUF1126 in human EF-hand domain
分子名称: EF-hand domain-containing family member C2
著者Saito, K, Kishishita, S, Nishino, A, Murayama, K, Terada, T, Shirouzu, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2007-05-07
公開日2007-11-13
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (1.84 Å)
主引用文献Crystal structure of the N-terminal DUF1126 in human EF-hand domain
To be Published
2YQF
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BU of 2yqf by Molmil
Solution structure of the death domain of Ankyrin-1
分子名称: Ankyrin-1
著者Tanabe, W, Suzuki, S, Muto, Y, Inoue, M, Kigawa, T, Terada, T, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2007-03-30
公開日2008-04-01
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Solution structure of the death domain of Ankyrin-1
To be Published
6WPP
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BU of 6wpp by Molmil
HUMAN NIK IN COMPLEX WITH LIGAND COMPOUND X
分子名称: 5-fluoro-N-methyl-2-(7H-pyrrolo[2,3-d]pyrimidin-5-yl)pyrimidin-4-amine, Mitogen-activated protein kinase kinase kinase 14
著者Shih, A.Y, Hack, M, Mirzadegan, T.
登録日2020-04-27
公開日2020-08-26
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Impact of Protein Preparation on Resulting Accuracy of FEP Calculations.
J.Chem.Inf.Model., 60, 2020
2YRJ
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BU of 2yrj by Molmil
Solution structure of the C2H2-type zinc finger domain (781-813) from zinc finger protein 473
分子名称: ZINC ION, Zinc finger protein 473
著者Qin, X.R, Izumi, K, Yoshida, M, Hayashi, F, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2007-04-02
公開日2007-10-02
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Solution structure of the C2H2-type zinc finger domain (781-813) from zinc finger protein 473
To be Published
6WP9
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BU of 6wp9 by Molmil
AvaR1 bound to Avenolide
分子名称: (5S)-5-[(6R)-6-hydroxy-6-methyl-5-oxooctyl]furan-2(5H)-one, AvaR1
著者Kapoor, I, Olivares, P.J, Nair, S.K.
登録日2020-04-26
公開日2020-07-22
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Biochemical basis for the regulation of biosynthesis of antiparasitics by bacterial hormones.
Elife, 9, 2020
2YRZ
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Solution structure of the fibronectin type III domain of human Integrin beta-4
分子名称: Integrin beta-4
著者Abe, H, Sasagawa, A, Tochio, N, Koshiba, S, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2007-04-03
公開日2008-04-08
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Solution structure of the fibronectin type III domain of human Integrin beta-4
To be Published
6WQ3
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BU of 6wq3 by Molmil
Crystal Structure of Nsp16-Nsp10 Heterodimer from SARS-CoV-2 in Complex with 7-methyl-GpppA and S-adenosyl-L-homocysteine.
分子名称: 2'-O-methyltransferase, 7N-METHYL-8-HYDROGUANOSINE-5'-DIPHOSPHATE, Non-structural protein 10, ...
著者Minasov, G, Shuvalova, L, Rosas-Lemus, M, Brunzelle, J.S, Kiryukhina, O, Satchell, K.J.F, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2020-04-28
公開日2020-05-06
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献High-resolution structures of the SARS-CoV-2 2'- O -methyltransferase reveal strategies for structure-based inhibitor design.
Sci.Signal., 13, 2020
2YSH
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BU of 2ysh by Molmil
Solution structure of the WW domain from the human growth-arrest-specific protein 7, GAS-7
分子名称: Growth-arrest-specific protein 7
著者Ohnishi, S, Tochio, N, Sato, M, Koshiba, S, Harada, T, Watanabe, S, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2007-04-03
公開日2007-10-09
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Solution structure of the WW domain from the human growth-arrest-specific protein 7, GAS-7
To be Published
2YSX
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BU of 2ysx by Molmil
Solution structure of the human SHIP SH2 domain
分子名称: Signaling inositol polyphosphate phosphatase SHIP II
著者Kasai, T, Koshiba, S, Watanabe, S, Harada, T, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2007-04-04
公開日2008-04-08
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Solution structure of the human SHIP SH2 domain
To be Published
2YTJ
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BU of 2ytj by Molmil
Solution structure of the C2H2 type zinc finger (region 771-803) of human Zinc finger protein 484
分子名称: ZINC ION, Zinc finger protein 484
著者Tomizawa, T, Tochio, N, Abe, H, Saito, K, Li, H, Sato, M, Koshiba, S, Kobayashi, N, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2007-04-05
公開日2007-10-09
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Solution structure of the C2H2 type zinc finger (region 771-803) of human Zinc finger protein 484
To be Published
6WQ8
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BU of 6wq8 by Molmil
Carbonic Anhydrase II Complexed with 3-((2-((Furan-2-ylmethyl)(4-sulfamoylphenethyl)amino)-2-oxoethyl)(phenethyl)amino)propanoic acid
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Carbonic anhydrase 2, GLYCEROL, ...
著者Andring, J.T, Combs, J.E, Lomelino, C, McKenna, R.
登録日2020-04-28
公開日2020-06-24
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.405 Å)
主引用文献Sulfonamide Inhibitors of Human Carbonic Anhydrases Designed through a Three-Tails Approach: Improving Ligand/Isoform Matching and Selectivity of Action.
J.Med.Chem., 63, 2020
6DBE
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BU of 6dbe by Molmil
Crystal Structure of VHH R330
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, nanobody VHH R303
著者Brooks, C.L, Toride King, M, Huh, I.
登録日2018-05-03
公開日2018-07-18
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Structural basis of VHH-mediated neutralization of the food-borne pathogenListeria monocytogenes.
J. Biol. Chem., 293, 2018
2YTX
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BU of 2ytx by Molmil
Solution structure of the second cold-shock domain of the human KIAA0885 protein (UNR protein)
分子名称: Cold shock domain-containing protein E1
著者Goroncy, A.K, Tomizawa, T, Koshiba, S, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2007-04-05
公開日2008-04-08
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献The NMR solution structures of the five constituent cold-shock domains (CSD) of the human UNR (upstream of N-ras) protein.
J.Struct.Funct.Genom., 11, 2010
2YUJ
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BU of 2yuj by Molmil
Solution structure of human ubiquitin fusion degradation protein 1 homolog UFD1
分子名称: Ubiquitin fusion degradation 1-like
著者Saito, K, Tomizawa, T, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2007-04-06
公開日2008-04-15
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Solution structure of human ubiquitin fusion degradation protein 1 homolog UFD1
To be Published
6WTF
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BU of 6wtf by Molmil
Structure of radical S-adenosylmethionine methyltransferase, TsrM, from Kitasatospora setae with tryptophan substrate and SAM analog (aza-SAM) bound
分子名称: COBALAMIN, IRON/SULFUR CLUSTER, S-5'-AZAMETHIONINE-5'-DEOXYADENOSINE, ...
著者Knox, H.L, Chen, P.Y.-T, Drennan, C.L, Booker, S.J.
登録日2020-05-02
公開日2020-12-23
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.19 Å)
主引用文献Structural basis for non-radical catalysis by TsrM, a radical SAM methylase.
Nat.Chem.Biol., 17, 2021
4UAC
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EUR_01830 with acarbose
分子名称: 1,2-ETHANEDIOL, 4,6-dideoxy-4-{[(1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl]amino}-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, Carbohydrate ABC transporter substrate-binding protein, ...
著者Koropatkin, N.M, Orlovsky, N.I.
登録日2014-08-08
公開日2014-12-10
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Molecular details of a starch utilization pathway in the human gut symbiont Eubacterium rectale.
Mol.Microbiol., 95, 2015
6WRZ
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BU of 6wrz by Molmil
Crystal Structure of Nsp16-Nsp10 Heterodimer from SARS-CoV-2 with 7-methyl-GpppA and S-adenosyl-L-homocysteine in the Active Site and Sulfates in the mRNA Binding Groove.
分子名称: 2'-O-methyltransferase, 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE, CHLORIDE ION, ...
著者Minasov, G, Shuvalova, L, Rosas-Lemus, M, Brunzelle, J.S, Kiryukhina, O, Satchell, K.J.F, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2020-04-30
公開日2020-05-13
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献High-resolution structures of the SARS-CoV-2 2'- O -methyltransferase reveal strategies for structure-based inhibitor design.
Sci.Signal., 13, 2020
2YXH
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Crystal structure of mazG-related protein from Thermotoga maritima
分子名称: MAGNESIUM ION, MazG-related protein
著者Padmanabhan, B, Bessho, Y, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2007-04-26
公開日2007-10-30
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structure of mazG-related protein from Thermotoga maritima
To be Published
6WW3
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Crystal structure of HERC2 ZZ domain in complex with SUMO1 tail
分子名称: DI(HYDROXYETHYL)ETHER, GLYCEROL, SUMO1 linked HERC2 ZZ domain (Small ubiquitin-related modifier 1,E3 ubiquitin-protein ligase HERC2), ...
著者Liu, J, Vann, K.R, Kutateladze, T.G.
登録日2020-05-07
公開日2020-08-05
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.096 Å)
主引用文献Structural Insight into Binding of the ZZ Domain of HERC2 to Histone H3 and SUMO1.
Structure, 28, 2020
6WW8
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BRD4 Bromodomain 1 in complex with triple CDK4/6-PI3K-BET inhibitor
分子名称: 7-cyclopentyl-N,N-dimethyl-2-({4-[5-(morpholin-4-yl)-7-oxo-7H-thieno[3,2-b]pyran-3-yl]phenyl}amino)-7H-pyrrolo[2,3-d]pyrimidine-6-carboxamide, Bromodomain-containing protein 4
著者Vann, K.R, Kutateladze, T.G.
登録日2020-05-08
公開日2020-08-26
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.302 Å)
主引用文献A triple action CDK4/6-PI3K-BET inhibitor with augmented cancer cell cytotoxicity.
Cell Discov, 6, 2020
6WTT
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Crystals Structure of the SARS-CoV-2 (COVID-19) main protease with inhibitor GC-376
分子名称: (1R,2S)-2-({N-[(benzyloxy)carbonyl]-L-leucyl}amino)-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]propane-1-sulfonic acid, (1S,2S)-2-({N-[(benzyloxy)carbonyl]-L-leucyl}amino)-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]propane-1-sulfonic acid, 3C-like proteinase, ...
著者Sacco, M, Ma, C, Chen, Y, Wang, J.
登録日2020-05-03
公開日2020-05-20
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Boceprevir, GC-376, and calpain inhibitors II, XII inhibit SARS-CoV-2 viral replication by targeting the viral main protease.
Cell Res., 30, 2020
2YZH
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Crystal structure of peroxiredoxin-like protein from Aquifex aeolicus
分子名称: Probable thiol peroxidase, SULFATE ION
著者Ebihara, A, Manzoku, M, Fujimoto, Y, Yokoyama, S, Kuramitsu, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2007-05-05
公開日2007-11-06
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Crystal structure of peroxiredoxin-like protein from Aquifex aeolicus
to be published

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件を2024-08-14に公開中

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