6N7N
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![BU of 6n7n by Molmil](/molmil-images/mine/6n7n) | Structure of bacteriophage T7 E343Q mutant gp4 helicase-primase in complex with ssDNA, dTTP, AC dinucleotide and CTP (form I) | 分子名称: | DNA (5'-D(P*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*T)-3'), DNA primase/helicase, MAGNESIUM ION, ... | 著者 | Gao, Y, Cui, Y, Zhou, Z, Yang, W. | 登録日 | 2018-11-27 | 公開日 | 2019-03-06 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Structures and operating principles of the replisome. Science, 363, 2019
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6OBJ
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![BU of 6obj by Molmil](/molmil-images/mine/6obj) | |
5GKR
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![BU of 5gkr by Molmil](/molmil-images/mine/5gkr) | Crystal structure of SLE patient-derived anti-DNA antibody in complex with oligonucleotide | 分子名称: | DNA (5'-D(P*TP*TP*TP*T)-3'), IgG2, Fab (heavy chain), ... | 著者 | Arimori, T, Sakakibara, S, Kikutani, H, Takagi, J. | 登録日 | 2016-07-05 | 公開日 | 2017-07-05 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Clonal evolution and antigen recognition of anti-nuclear antibodies in acute systemic lupus erythematosus Sci Rep, 7, 2017
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4ON0
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![BU of 4on0 by Molmil](/molmil-images/mine/4on0) | |
6X9I
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![BU of 6x9i by Molmil](/molmil-images/mine/6x9i) | Human DNMT1(729-1600) Bound to Zebularine-Containing 12mer dsDNA | 分子名称: | 1,2-ETHANEDIOL, DNA (5'-D(*GP*AP*GP*GP*CP*(5CM)P*GP*CP*CP*TP*GP*C)-3'), DNA (5'-D(*GP*CP*AP*GP*G)-R(P*(PYO))-D(P*GP*GP*CP*CP*TP*C)-3'), ... | 著者 | Pathuri, S, Horton, J.R, Cheng, X. | 登録日 | 2020-06-02 | 公開日 | 2021-07-07 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Discovery of a first-in-class reversible DNMT1-selective inhibitor with improved tolerability and efficacy in acute myeloid leukemia. Nat Cancer, 2, 2021
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2R5Z
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![BU of 2r5z by Molmil](/molmil-images/mine/2r5z) | Structure of Scr/Exd complex bound to a DNA sequence derived from the fkh gene | 分子名称: | DNA (5'-D(*DAP*DCP*DTP*DCP*DTP*DAP*DAP*DGP*DAP*DTP*DTP*DAP*DAP*DTP*DCP*DGP*DGP*DCP*DTP*DG)-3'), DNA (5'-D(*DTP*DCP*DAP*DGP*DCP*DCP*DGP*DAP*DTP*DTP*DAP*DAP*DTP*DCP*DTP*DTP*DAP*DGP*DAP*DG)-3'), Homeobox protein extradenticle, ... | 著者 | Aggarwal, A.K, Passner, J.M, Jain, R. | 登録日 | 2007-09-04 | 公開日 | 2008-02-05 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Functional specificity of a Hox protein mediated by the recognition of minor groove structure Cell(Cambridge,Mass.), 131, 2007
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5EYB
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![BU of 5eyb by Molmil](/molmil-images/mine/5eyb) | X-ray Structure of Reb1-Ter Complex | 分子名称: | DNA (26-MER), DNA-binding protein reb1 | 著者 | Jaiswal, R, Choudhury, M, Zaman, S, Singh, S, Santosh, V, Bastia, D, Escalante, C.R. | 登録日 | 2015-11-24 | 公開日 | 2016-04-13 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Functional architecture of the Reb1-Ter complex of Schizosaccharomyces pombe. Proc.Natl.Acad.Sci.USA, 113, 2016
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4OMY
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![BU of 4omy by Molmil](/molmil-images/mine/4omy) | |
7VO9
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![BU of 7vo9 by Molmil](/molmil-images/mine/7vo9) | |
6CRO
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![BU of 6cro by Molmil](/molmil-images/mine/6cro) | |
6EU1
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![BU of 6eu1 by Molmil](/molmil-images/mine/6eu1) | RNA Polymerase III - open DNA complex (OC-POL3). | 分子名称: | DNA-directed RNA polymerase III subunit RPC1, DNA-directed RNA polymerase III subunit RPC10, DNA-directed RNA polymerase III subunit RPC2, ... | 著者 | Abascal-Palacios, G, Ramsay, E.P, Beuron, F, Morris, E, Vannini, A. | 登録日 | 2017-10-27 | 公開日 | 2018-01-17 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Structural basis of RNA polymerase III transcription initiation. Nature, 553, 2018
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5VA0
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![BU of 5va0 by Molmil](/molmil-images/mine/5va0) | |
5VA7
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![BU of 5va7 by Molmil](/molmil-images/mine/5va7) | |
5FD3
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![BU of 5fd3 by Molmil](/molmil-images/mine/5fd3) | Structure of Lin54 tesmin domain bound to DNA | 分子名称: | DNA (5'-D(*CP*AP*GP*TP*TP*TP*CP*AP*AP*AP*CP*TP*C)-3'), DNA (5'-D(*GP*AP*GP*TP*TP*TP*GP*AP*AP*AP*CP*T)-3'), Protein lin-54 homolog, ... | 著者 | Marceau, A.H, Felthousen, J.G, Goetsch, P.D, Lee, H, Tripathi, S.M, Strome, S, Litovchick, L, Rubin, S.M. | 登録日 | 2015-12-15 | 公開日 | 2016-08-03 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.42 Å) | 主引用文献 | Structural basis for LIN54 recognition of CHR elements in cell cycle-regulated promoters. Nat Commun, 7, 2016
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6O6P
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![BU of 6o6p by Molmil](/molmil-images/mine/6o6p) | Structure of the regulator FasR from Mycobacterium tuberculosis in complex with DNA | 分子名称: | DNA-forward, DNA-reverse, TetR family transcriptional regulator | 著者 | Larrieux, N, Trajtenberg, F, Lara, J, Gramajo, H, Buschiazzo, A. | 登録日 | 2019-03-07 | 公開日 | 2020-03-11 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (3.851 Å) | 主引用文献 | Mycobacterium tuberculosis FasR senses long fatty acyl-CoA through a tunnel and a hydrophobic transmission spine. Nat Commun, 11, 2020
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2MD5
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![BU of 2md5 by Molmil](/molmil-images/mine/2md5) | Structure of uninhibited ETV6 ETS domain | 分子名称: | Transcription factor ETV6 | 著者 | De, S, Mcintosh, L.P, Chan, A.C, Coyne, H.J, Okon, M, Graves, B.J, Murphy, M.E. | 登録日 | 2013-08-29 | 公開日 | 2013-12-25 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Steric Mechanism of Auto-Inhibitory Regulation of Specific and Non-Specific DNA Binding by the ETS Transcriptional Repressor ETV6. J.Mol.Biol., 426, 2014
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7L4V
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![BU of 7l4v by Molmil](/molmil-images/mine/7l4v) | |
5T7X
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![BU of 5t7x by Molmil](/molmil-images/mine/5t7x) | Crystal structure of HHV-4 EBNA1 DNA binding domain (patient-derived, nasopharyngeal carcinoma) bound to DNA | 分子名称: | DNA (5'-D(*GP*GP*AP*TP*AP*GP*CP*CP*TP*AP*TP*GP*CP*TP*AP*CP*CP*C)-3'), DNA (5'-D(*GP*GP*GP*TP*AP*GP*CP*AP*TP*AP*GP*GP*CP*TP*AP*TP*CP*C)-3'), Epstein-Barr nuclear antigen 1 | 著者 | Malecka, K.A, Messick, T.E, Lieberman, P.M. | 登録日 | 2016-09-06 | 公開日 | 2017-07-19 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | Carcinoma-risk variant of EBNA1 deregulates Epstein-Barr Virus episomal latency. Oncotarget, 8, 2017
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8TIQ
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![BU of 8tiq by Molmil](/molmil-images/mine/8tiq) | Isoreticular, interpenetrating co-crystal of Replication Initiator Protein REPE54 and symmetrical expanded duplex (31mer) containing the cognate REPE54 sequence and an additional G-C rich sequence with blunt ends and 3' terminal phosphates. | 分子名称: | DNA (5'-D(*CP*CP*CP*GP*GP*AP*CP*CP*TP*GP*TP*GP*AP*CP*AP*AP*AP*TP*TP*GP*CP*CP*CP*TP*CP*AP*GP*AP*CP*GP*GP*A)-3', DNA (5'-D(*CP*CP*GP*TP*CP*TP*GP*AP*GP*GP*GP*CP*AP*AP*TP*TP*TP*GP*TP*CP*AP*CP*AP*GP*GP*TP*CP*CP*GP*GP*GP*A)-3'), MAGNESIUM ION, ... | 著者 | Orun, A.R, Shields, E.T, Slaughter, C.K, Shrestha, R, Snow, C.D. | 登録日 | 2023-07-20 | 公開日 | 2023-08-02 | 最終更新日 | 2024-08-14 | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | 主引用文献 | Tuning chemical DNA ligation within DNA crystals and protein-DNA co-crystals Acs Nanosci Au, 2024
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8TIU
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![BU of 8tiu by Molmil](/molmil-images/mine/8tiu) | Isoreticular, interpenetrating co-crystal of Replication Initiator Protein REPE54 and symmetrical expanded duplex (31mer) containing the cognate REPE54 sequence and an additional G-C rich sequence with 2 sticky base overhangs and 3' terminal phosphates. | 分子名称: | DNA (5'-D(CP*CP*CP*GP*GP*AP*CP*CP*TP*GP*TP*GP*AP*CP*AP*AP*AP*TP*TP*GP*CP*CP*CP*TP*CP*AP*GP*AP*CP*GP*GP*A)-3')|, DNA (5'-D(GP*GP*CP*CP*GP*TP*CP*TP*GP*AP*GP*GP*GP*CP*AP*AP*TP*TP*TP*GP*TP*CP*AP*CP*AP*GP*GP*TP*CP*CP*GP*A)-3'), MAGNESIUM ION, ... | 著者 | Orun, A.R, Shields, E.T, Shrestha, R, Slaughter, C.K, Snow, C.D. | 登録日 | 2023-07-20 | 公開日 | 2023-08-02 | 最終更新日 | 2024-08-14 | 実験手法 | X-RAY DIFFRACTION (3.9 Å) | 主引用文献 | Tuning chemical DNA ligation within DNA crystals and protein-DNA co-crystals Acs Nanosci Au, 2024
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8TIT
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![BU of 8tit by Molmil](/molmil-images/mine/8tit) | Isoreticular, interpenetrating co-crystal of Replication Initiator Protein REPE54 and symmetrical expanded duplex (31mer) containing the cognate REPE54 sequence and an additional G-C rich sequence with 2 sticky base overhangs and no terminal phosphates. | 分子名称: | DNA (5'-D(CP*CP*CP*GP*GP*AP*CP*CP*TP*GP*TP*GP*AP*CP*AP*AP*AP*TP*TP*GP*CP*CP*CP*TP*CP*AP*GP*AP*CP*GP*G)-3')|, DNA (5'-D(GP*GP*CP*CP*GP*TP*CP*TP*GP*AP*GP*GP*GP*CP*AP*AP*TP*TP*TP*GP*TP*CP*AP*CP*AP*GP*GP*TP*CP*CP*GP)-3'), MAGNESIUM ION, ... | 著者 | Orun, A.R, Shields, E.T, Shrestha, R, Slaughter, C.K, Snow, C.D. | 登録日 | 2023-07-20 | 公開日 | 2023-08-02 | 最終更新日 | 2024-08-14 | 実験手法 | X-RAY DIFFRACTION (2.84 Å) | 主引用文献 | Tuning chemical DNA ligation within DNA crystals and protein-DNA co-crystals Acs Nanosci Au, 2024
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8TIZ
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![BU of 8tiz by Molmil](/molmil-images/mine/8tiz) | Isoreticular, interpenetrating co-crystal of Replication Initiator Protein REPE54 and symmetrical expanded duplex (31mer) containing the cognate REPE54 sequence and an additional G-C rich sequence with 2 sticky base overhangs and no terminal phosphates and crosslinked with EDC. | 分子名称: | DNA (5'-D(CP*CP*CP*GP*GP*AP*CP*CP*TP*GP*TP*GP*AP*CP*AP*AP*AP*TP*TP*GP*CP*CP*CP*TP*CP*AP*GP*AP*CP*GP*G)-3')|, DNA (5'-D(GP*GP*CP*CP*GP*TP*CP*TP*GP*AP*GP*GP*GP*CP*AP*AP*TP*TP*TP*GP*TP*CP*AP*CP*AP*GP*GP*TP*CP*CP*GP)-3'), MAGNESIUM ION, ... | 著者 | Orun, A.R, Shields, E.T, Shrestha, R, Slaughter, C.K, Snow, C.D. | 登録日 | 2023-07-20 | 公開日 | 2023-08-02 | 最終更新日 | 2024-08-14 | 実験手法 | X-RAY DIFFRACTION (3.11 Å) | 主引用文献 | Tuning chemical DNA ligation within DNA crystals and protein-DNA co-crystals Acs Nanosci Au, 2024
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8TIS
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![BU of 8tis by Molmil](/molmil-images/mine/8tis) | Isoreticular, interpenetrating co-crystal of Replication Initiator Protein REPE54 and symmetrical expanded duplex (31mer) containing the cognate REPE54 sequence and an additional G-C rich sequence with 1 sticky bases and 3' terminal phosphates. | 分子名称: | DNA (5'-D(GP*CP*CP*GP*TP*CP*TP*GP*AP*GP*GP*GP*CP*AP*AP*TP*TP*TP*GP*TP*CP*AP*CP*AP*GP*GP*TP*CP*CP*GP*GP*A)-3'), DNA(5'-D(CP*CP*CP*GP*GP*AP*CP*CP*TP*GP*TP*GP*AP*CP*AP*AP*AP*TP*TP*GP*CP*CP*CP*TP*CP*AP*GP*AP*CP*GP*GP*A)-')|, MAGNESIUM ION, ... | 著者 | Orun, A.R, Shields, E.T, Shrestha, R, Slaughter, C.K, Snow, C.D. | 登録日 | 2023-07-20 | 公開日 | 2023-08-02 | 最終更新日 | 2024-08-14 | 実験手法 | X-RAY DIFFRACTION (2.54 Å) | 主引用文献 | Tuning chemical DNA ligation within DNA crystals and protein-DNA co-crystals Acs Nanosci Au, 2024
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8TJ0
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![BU of 8tj0 by Molmil](/molmil-images/mine/8tj0) | Isoreticular, interpenetrating co-crystal of Replication Initiator Protein REPE54 and symmetrical expanded duplex (31mer) containing the cognate REPE54 sequence and an additional G-C rich sequence with 2 sticky base overhangs and 5' terminal phosphates and crosslinked with EDC. | 分子名称: | DNA (5'-D(A*CP*CP*CP*GP*GP*AP*CP*CP*TP*GP*TP*GP*AP*CP*AP*AP*AP*TP*TP*GP*CP*CP*CP*TP*CP*AP*GP*AP*CP*GP*G)-3'), DNA (5'-D(A*GP*GP*CP*CP*GP*TP*CP*TP*GP*AP*GP*GP*GP*CP*AP*AP*TP*TP*TP*GP*TP*CP*AP*CP*AP*GP*GP*TP*CP*CP*G)-3'), MAGNESIUM ION, ... | 著者 | Orun, A.R, Shields, E.T, Slaughter, C.K, Shrestha, R, Snow, C.D. | 登録日 | 2023-07-20 | 公開日 | 2023-08-02 | 最終更新日 | 2024-08-14 | 実験手法 | X-RAY DIFFRACTION (3.24 Å) | 主引用文献 | Tuning chemical DNA ligation within DNA crystals and protein-DNA co-crystals Acs Nanosci Au, 2024
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8TIW
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![BU of 8tiw by Molmil](/molmil-images/mine/8tiw) | Isoreticular, interpenetrating co-crystal of Replication Initiator Protein REPE54 and symmetrical expanded duplex (31mer) containing the cognate REPE54 sequence and an additional G-C rich sequence with blunt ends and 3' terminal phosphates and crosslinked with EDC. | 分子名称: | DNA (5'-D(*CP*CP*CP*GP*GP*AP*CP*CP*TP*GP*TP*GP*AP*CP*AP*AP*AP*TP*TP*GP*CP*CP*CP*TP*CP*AP*GP*AP*CP*GP*GP*A)-3', DNA (5'-D(*CP*CP*GP*TP*CP*TP*GP*AP*GP*GP*GP*CP*AP*AP*TP*TP*TP*GP*TP*CP*AP*CP*AP*GP*GP*TP*CP*CP*GP*GP*GP*A)-3'), MAGNESIUM ION, ... | 著者 | Orun, A.R, Shields, E.T, Shrestha, R, Slaughter, C.K, Snow, C.D. | 登録日 | 2023-07-20 | 公開日 | 2023-08-02 | 最終更新日 | 2024-08-14 | 実験手法 | X-RAY DIFFRACTION (3.11 Å) | 主引用文献 | Tuning chemical DNA ligation within DNA crystals and protein-DNA co-crystals Acs Nanosci Au, 2024
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