PDB: 45953 件ウェブページステータス検索Chemie searchBIRD

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6N7N	Structure of bacteriophage T7 E343Q mutant gp4 helicase-primase in complex with ssDNA, dTTP, AC dinucleotide and CTP (form I) 分子名称: DNA (5'-D(P*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*T)-3'), DNA primase/helicase, MAGNESIUM ION, ... 著者 Gao, Y, Cui, Y, Zhou, Z, Yang, W. 登録日 2018-11-27 公開日 2019-03-06 最終更新日 2024-03-20 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 Structures and operating principles of the replisome. Science, 363, 2019
6OBJ	Structure of a DNA-bound dimer extracted from filamentous SgrAI endonuclease in its activated form 分子名称: DNA (26-MER), MAGNESIUM ION, SgraIR restriction enzyme 著者 Polley, S, Lyumkis, D, Horton, N.C. 登録日 2019-03-20 公開日 2020-02-26 最終更新日 2024-03-20 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 Mechanism of Filamentation-Induced Allosteric Activation of the SgrAI Endonuclease. Structure, 27, 2019
5GKR	Crystal structure of SLE patient-derived anti-DNA antibody in complex with oligonucleotide 分子名称: DNA (5'-D(P*TP*TP*TP*T)-3'), IgG2, Fab (heavy chain), ... 著者 Arimori, T, Sakakibara, S, Kikutani, H, Takagi, J. 登録日 2016-07-05 公開日 2017-07-05 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Clonal evolution and antigen recognition of anti-nuclear antibodies in acute systemic lupus erythematosus Sci Rep, 7, 2017
4ON0	Crystal Structure of NolR from Sinorhizobium fredii in complex with oligo AA DNA 分子名称: DNA (5 -D(*TP*AP*AP*TP*CP*TP*CP*TP*TP*GP*GP*GP*AP*CP*TP*AP*CP*AP*AP*TP*TP*A)-3 ), DNA (5 -D(*TP*AP*TP*TP*AP*GP*AP*GP*AP*AP*CP*CP*CP*TP*GP*AP*TP*GP*TP*TP*AP*A)-3 ), NolR 著者 Lee, S.G, Krishnan, H.B, Jez, J.M. 登録日 2014-01-28 公開日 2014-04-16 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Structural basis for regulation of rhizobial nodulation and symbiosis gene expression by the regulatory protein NolR. Proc.Natl.Acad.Sci.USA, 111, 2014
6X9I	Human DNMT1(729-1600) Bound to Zebularine-Containing 12mer dsDNA 分子名称: 1,2-ETHANEDIOL, DNA (5'-D(*GP*AP*GP*GP*CP*(5CM)P*GP*CP*CP*TP*GP*C)-3'), DNA (5'-D(*GP*CP*AP*GP*G)-R(P*(PYO))-D(P*GP*GP*CP*CP*TP*C)-3'), ... 著者 Pathuri, S, Horton, J.R, Cheng, X. 登録日 2020-06-02 公開日 2021-07-07 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Discovery of a first-in-class reversible DNMT1-selective inhibitor with improved tolerability and efficacy in acute myeloid leukemia. Nat Cancer, 2, 2021
2R5Z	Structure of Scr/Exd complex bound to a DNA sequence derived from the fkh gene 分子名称: DNA (5'-D(*DAP*DCP*DTP*DCP*DTP*DAP*DAP*DGP*DAP*DTP*DTP*DAP*DAP*DTP*DCP*DGP*DGP*DCP*DTP*DG)-3'), DNA (5'-D(*DTP*DCP*DAP*DGP*DCP*DCP*DGP*DAP*DTP*DTP*DAP*DAP*DTP*DCP*DTP*DTP*DAP*DGP*DAP*DG)-3'), Homeobox protein extradenticle, ... 著者 Aggarwal, A.K, Passner, J.M, Jain, R. 登録日 2007-09-04 公開日 2008-02-05 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Functional specificity of a Hox protein mediated by the recognition of minor groove structure Cell(Cambridge,Mass.), 131, 2007
5EYB	X-ray Structure of Reb1-Ter Complex 分子名称: DNA (26-MER), DNA-binding protein reb1 著者 Jaiswal, R, Choudhury, M, Zaman, S, Singh, S, Santosh, V, Bastia, D, Escalante, C.R. 登録日 2015-11-24 公開日 2016-04-13 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Functional architecture of the Reb1-Ter complex of Schizosaccharomyces pombe. Proc.Natl.Acad.Sci.USA, 113, 2016
4OMY	Crystal Structure of SeMet NolR from Sinorhizobium fredii in complex with oligo AT DNA 分子名称: DNA (5 -D(*TP*AP*AP*TP*CP*TP*CP*TP*TP*GP*GP*GP*AP*CP*TP*TP*CP*AP*AP*TP*TP*A)-3 ), DNA (5 -D(*TP*AP*TP*TP*AP*GP*AP*GP*AP*AP*CP*CP*CP*TP*GP*AP*AP*GP*TP*TP*AP*A)-3 ), NolR 著者 Lee, S.G, Krishnan, H.B, Jez, J.M. 登録日 2014-01-28 公開日 2014-04-16 最終更新日 2014-06-04 実験手法 X-RAY DIFFRACTION (3.062 Å) 主引用文献 Structural basis for regulation of rhizobial nodulation and symbiosis gene expression by the regulatory protein NolR. Proc.Natl.Acad.Sci.USA, 111, 2014
7VO9	Streptomyces coelicolor zinc uptake regulator complexed with zinc and DNA (dimer of dimers) 分子名称: DNA (84-MER), Putative metal uptake regulation protein, ZINC ION 著者 Yang, X, Zheng, J. 登録日 2021-10-13 公開日 2022-08-03 最終更新日 2024-06-19 実験手法 ELECTRON MICROSCOPY (3.8 Å) 主引用文献 Structural basis of Streptomyces transcription activation by zinc uptake regulator. Nucleic Acids Res., 50, 2022
6CRO	CRYSTAL STRUCTURE OF LAMBDA-CRO BOUND TO A CONSENSUS OPERATOR AT 3.0 ANGSTROM RESOLUTION 分子名称: DNA (5'-D(*AP*CP*TP*AP*TP*CP*AP*CP*CP*GP*CP*GP*GP*GP*TP*GP*AP*TP*AP*C)-3'), DNA (5'-D(*TP*GP*TP*AP*TP*CP*AP*CP*CP*CP*GP*CP*GP*GP*TP*GP*AP*TP*AP*G)-3'), LAMBDA CRO REPRESSOR, ... 著者 Albright, R.A, Matthews, B.W. 登録日 1998-04-22 公開日 1998-09-18 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Crystal structure of lambda-Cro bound to a consensus operator at 3.0 A resolution. J.Mol.Biol., 280, 1998
6EU1	RNA Polymerase III - open DNA complex (OC-POL3). 分子名称: DNA-directed RNA polymerase III subunit RPC1, DNA-directed RNA polymerase III subunit RPC10, DNA-directed RNA polymerase III subunit RPC2, ... 著者 Abascal-Palacios, G, Ramsay, E.P, Beuron, F, Morris, E, Vannini, A. 登録日 2017-10-27 公開日 2018-01-17 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 Structural basis of RNA polymerase III transcription initiation. Nature, 553, 2018
5VA0	Glucocorticoid Receptor DNA Binding Domain in complex with AP-1 response element from VCAM-1 Promoter 分子名称: DNA (5'-D(*CP*GP*GP*CP*TP*GP*AP*CP*TP*CP*AP*TP*CP*AP*AP*G)-3'), DNA (5'-D(*CP*TP*TP*GP*AP*TP*GP*AP*GP*TP*CP*AP*GP*CP*CP*G)-3'), Glucocorticoid receptor, ... 著者 Weikum, E.R, Ortlund, E.A. 登録日 2017-03-24 公開日 2017-08-09 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.295 Å) 主引用文献 Tethering not required: the glucocorticoid receptor binds directly to activator protein-1 recognition motifs to repress inflammatory genes. Nucleic Acids Res., 45, 2017
5VA7	Glucocorticoid Receptor DNA Binding Domain - IL11 AP-1 recognition element Complex 分子名称: DNA (5'-D(*AP*GP*GP*GP*TP*GP*AP*GP*TP*CP*AP*GP*GP*AP*TP*G)-3'), DNA (5'-D(*CP*AP*TP*CP*CP*TP*GP*AP*CP*TP*CP*AP*CP*CP*CP*T)-3'), Glucocorticoid receptor, ... 著者 Weikum, E.R, Ortlund, E.A. 登録日 2017-03-24 公開日 2017-08-09 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.153 Å) 主引用文献 Tethering not required: the glucocorticoid receptor binds directly to activator protein-1 recognition motifs to repress inflammatory genes. Nucleic Acids Res., 45, 2017
5FD3	Structure of Lin54 tesmin domain bound to DNA 分子名称: DNA (5'-D(*CP*AP*GP*TP*TP*TP*CP*AP*AP*AP*CP*TP*C)-3'), DNA (5'-D(*GP*AP*GP*TP*TP*TP*GP*AP*AP*AP*CP*T)-3'), Protein lin-54 homolog, ... 著者 Marceau, A.H, Felthousen, J.G, Goetsch, P.D, Lee, H, Tripathi, S.M, Strome, S, Litovchick, L, Rubin, S.M. 登録日 2015-12-15 公開日 2016-08-03 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.42 Å) 主引用文献 Structural basis for LIN54 recognition of CHR elements in cell cycle-regulated promoters. Nat Commun, 7, 2016
6O6P	Structure of the regulator FasR from Mycobacterium tuberculosis in complex with DNA 分子名称: DNA-forward, DNA-reverse, TetR family transcriptional regulator 著者 Larrieux, N, Trajtenberg, F, Lara, J, Gramajo, H, Buschiazzo, A. 登録日 2019-03-07 公開日 2020-03-11 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (3.851 Å) 主引用文献 Mycobacterium tuberculosis FasR senses long fatty acyl-CoA through a tunnel and a hydrophobic transmission spine. Nat Commun, 11, 2020
2MD5	Structure of uninhibited ETV6 ETS domain 分子名称: Transcription factor ETV6 著者 De, S, Mcintosh, L.P, Chan, A.C, Coyne, H.J, Okon, M, Graves, B.J, Murphy, M.E. 登録日 2013-08-29 公開日 2013-12-25 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Steric Mechanism of Auto-Inhibitory Regulation of Specific and Non-Specific DNA Binding by the ETS Transcriptional Repressor ETV6. J.Mol.Biol., 426, 2014
7L4V	C-terminal bZIP domain of human C/EBPbeta Bound to DNA with Consensus Recognition with GT Mismatch 分子名称: 1,2-ETHANEDIOL, CCAAT/enhancer-binding protein beta, DNA Strand 1, ... 著者 Horton, J.R, Cheng, X. 登録日 2020-12-21 公開日 2021-11-03 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Preferential CEBP binding to T:G mismatches and increased C-to-T human somatic mutations. Nucleic Acids Res., 49, 2021
5T7X	Crystal structure of HHV-4 EBNA1 DNA binding domain (patient-derived, nasopharyngeal carcinoma) bound to DNA 分子名称: DNA (5'-D(*GP*GP*AP*TP*AP*GP*CP*CP*TP*AP*TP*GP*CP*TP*AP*CP*CP*C)-3'), DNA (5'-D(*GP*GP*GP*TP*AP*GP*CP*AP*TP*AP*GP*GP*CP*TP*AP*TP*CP*C)-3'), Epstein-Barr nuclear antigen 1 著者 Malecka, K.A, Messick, T.E, Lieberman, P.M. 登録日 2016-09-06 公開日 2017-07-19 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 Carcinoma-risk variant of EBNA1 deregulates Epstein-Barr Virus episomal latency. Oncotarget, 8, 2017
8TIQ	Isoreticular, interpenetrating co-crystal of Replication Initiator Protein REPE54 and symmetrical expanded duplex (31mer) containing the cognate REPE54 sequence and an additional G-C rich sequence with blunt ends and 3' terminal phosphates. 分子名称: DNA (5'-D(*CP*CP*CP*GP*GP*AP*CP*CP*TP*GP*TP*GP*AP*CP*AP*AP*AP*TP*TP*GP*CP*CP*CP*TP*CP*AP*GP*AP*CP*GP*GP*A)-3', DNA (5'-D(*CP*CP*GP*TP*CP*TP*GP*AP*GP*GP*GP*CP*AP*AP*TP*TP*TP*GP*TP*CP*AP*CP*AP*GP*GP*TP*CP*CP*GP*GP*GP*A)-3'), MAGNESIUM ION, ... 著者 Orun, A.R, Shields, E.T, Slaughter, C.K, Shrestha, R, Snow, C.D. 登録日 2023-07-20 公開日 2023-08-02 最終更新日 2024-08-14 実験手法 X-RAY DIFFRACTION (2.45 Å) 主引用文献 Tuning chemical DNA ligation within DNA crystals and protein-DNA co-crystals Acs Nanosci Au, 2024
8TIU	Isoreticular, interpenetrating co-crystal of Replication Initiator Protein REPE54 and symmetrical expanded duplex (31mer) containing the cognate REPE54 sequence and an additional G-C rich sequence with 2 sticky base overhangs and 3' terminal phosphates. 分子名称: DNA (5'-D(CP*CP*CP*GP*GP*AP*CP*CP*TP*GP*TP*GP*AP*CP*AP*AP*AP*TP*TP*GP*CP*CP*CP*TP*CP*AP*GP*AP*CP*GP*GP*A)-3')|, DNA (5'-D(GP*GP*CP*CP*GP*TP*CP*TP*GP*AP*GP*GP*GP*CP*AP*AP*TP*TP*TP*GP*TP*CP*AP*CP*AP*GP*GP*TP*CP*CP*GP*A)-3'), MAGNESIUM ION, ... 著者 Orun, A.R, Shields, E.T, Shrestha, R, Slaughter, C.K, Snow, C.D. 登録日 2023-07-20 公開日 2023-08-02 最終更新日 2024-08-14 実験手法 X-RAY DIFFRACTION (3.9 Å) 主引用文献 Tuning chemical DNA ligation within DNA crystals and protein-DNA co-crystals Acs Nanosci Au, 2024
8TIT	Isoreticular, interpenetrating co-crystal of Replication Initiator Protein REPE54 and symmetrical expanded duplex (31mer) containing the cognate REPE54 sequence and an additional G-C rich sequence with 2 sticky base overhangs and no terminal phosphates. 分子名称: DNA (5'-D(CP*CP*CP*GP*GP*AP*CP*CP*TP*GP*TP*GP*AP*CP*AP*AP*AP*TP*TP*GP*CP*CP*CP*TP*CP*AP*GP*AP*CP*GP*G)-3')|, DNA (5'-D(GP*GP*CP*CP*GP*TP*CP*TP*GP*AP*GP*GP*GP*CP*AP*AP*TP*TP*TP*GP*TP*CP*AP*CP*AP*GP*GP*TP*CP*CP*GP)-3'), MAGNESIUM ION, ... 著者 Orun, A.R, Shields, E.T, Shrestha, R, Slaughter, C.K, Snow, C.D. 登録日 2023-07-20 公開日 2023-08-02 最終更新日 2024-08-14 実験手法 X-RAY DIFFRACTION (2.84 Å) 主引用文献 Tuning chemical DNA ligation within DNA crystals and protein-DNA co-crystals Acs Nanosci Au, 2024
8TIZ	Isoreticular, interpenetrating co-crystal of Replication Initiator Protein REPE54 and symmetrical expanded duplex (31mer) containing the cognate REPE54 sequence and an additional G-C rich sequence with 2 sticky base overhangs and no terminal phosphates and crosslinked with EDC. 分子名称: DNA (5'-D(CP*CP*CP*GP*GP*AP*CP*CP*TP*GP*TP*GP*AP*CP*AP*AP*AP*TP*TP*GP*CP*CP*CP*TP*CP*AP*GP*AP*CP*GP*G)-3')|, DNA (5'-D(GP*GP*CP*CP*GP*TP*CP*TP*GP*AP*GP*GP*GP*CP*AP*AP*TP*TP*TP*GP*TP*CP*AP*CP*AP*GP*GP*TP*CP*CP*GP)-3'), MAGNESIUM ION, ... 著者 Orun, A.R, Shields, E.T, Shrestha, R, Slaughter, C.K, Snow, C.D. 登録日 2023-07-20 公開日 2023-08-02 最終更新日 2024-08-14 実験手法 X-RAY DIFFRACTION (3.11 Å) 主引用文献 Tuning chemical DNA ligation within DNA crystals and protein-DNA co-crystals Acs Nanosci Au, 2024
8TIS	Isoreticular, interpenetrating co-crystal of Replication Initiator Protein REPE54 and symmetrical expanded duplex (31mer) containing the cognate REPE54 sequence and an additional G-C rich sequence with 1 sticky bases and 3' terminal phosphates. 分子名称: DNA (5'-D(GP*CP*CP*GP*TP*CP*TP*GP*AP*GP*GP*GP*CP*AP*AP*TP*TP*TP*GP*TP*CP*AP*CP*AP*GP*GP*TP*CP*CP*GP*GP*A)-3'), DNA(5'-D(CP*CP*CP*GP*GP*AP*CP*CP*TP*GP*TP*GP*AP*CP*AP*AP*AP*TP*TP*GP*CP*CP*CP*TP*CP*AP*GP*AP*CP*GP*GP*A)-')|, MAGNESIUM ION, ... 著者 Orun, A.R, Shields, E.T, Shrestha, R, Slaughter, C.K, Snow, C.D. 登録日 2023-07-20 公開日 2023-08-02 最終更新日 2024-08-14 実験手法 X-RAY DIFFRACTION (2.54 Å) 主引用文献 Tuning chemical DNA ligation within DNA crystals and protein-DNA co-crystals Acs Nanosci Au, 2024
8TJ0	Isoreticular, interpenetrating co-crystal of Replication Initiator Protein REPE54 and symmetrical expanded duplex (31mer) containing the cognate REPE54 sequence and an additional G-C rich sequence with 2 sticky base overhangs and 5' terminal phosphates and crosslinked with EDC. 分子名称: DNA (5'-D(A*CP*CP*CP*GP*GP*AP*CP*CP*TP*GP*TP*GP*AP*CP*AP*AP*AP*TP*TP*GP*CP*CP*CP*TP*CP*AP*GP*AP*CP*GP*G)-3'), DNA (5'-D(A*GP*GP*CP*CP*GP*TP*CP*TP*GP*AP*GP*GP*GP*CP*AP*AP*TP*TP*TP*GP*TP*CP*AP*CP*AP*GP*GP*TP*CP*CP*G)-3'), MAGNESIUM ION, ... 著者 Orun, A.R, Shields, E.T, Slaughter, C.K, Shrestha, R, Snow, C.D. 登録日 2023-07-20 公開日 2023-08-02 最終更新日 2024-08-14 実験手法 X-RAY DIFFRACTION (3.24 Å) 主引用文献 Tuning chemical DNA ligation within DNA crystals and protein-DNA co-crystals Acs Nanosci Au, 2024
8TIW	Isoreticular, interpenetrating co-crystal of Replication Initiator Protein REPE54 and symmetrical expanded duplex (31mer) containing the cognate REPE54 sequence and an additional G-C rich sequence with blunt ends and 3' terminal phosphates and crosslinked with EDC. 分子名称: DNA (5'-D(*CP*CP*CP*GP*GP*AP*CP*CP*TP*GP*TP*GP*AP*CP*AP*AP*AP*TP*TP*GP*CP*CP*CP*TP*CP*AP*GP*AP*CP*GP*GP*A)-3', DNA (5'-D(*CP*CP*GP*TP*CP*TP*GP*AP*GP*GP*GP*CP*AP*AP*TP*TP*TP*GP*TP*CP*AP*CP*AP*GP*GP*TP*CP*CP*GP*GP*GP*A)-3'), MAGNESIUM ION, ... 著者 Orun, A.R, Shields, E.T, Shrestha, R, Slaughter, C.K, Snow, C.D. 登録日 2023-07-20 公開日 2023-08-02 最終更新日 2024-08-14 実験手法 X-RAY DIFFRACTION (3.11 Å) 主引用文献 Tuning chemical DNA ligation within DNA crystals and protein-DNA co-crystals Acs Nanosci Au, 2024

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