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2RH5
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BU of 2rh5 by Molmil
Structure of Apo Adenylate Kinase from Aquifex Aeolicus
分子名称: Adenylate kinase
著者Thai, V, Wolf-Watz, M, Fenn, T, Pozharski, E, Wilson, M.A, Petsko, G.A, Kern, D.
登録日2007-10-05
公開日2007-12-18
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.48 Å)
主引用文献Intrinsic motions along an enzymatic reaction trajectory.
Nature, 450, 2007
2P3S
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BU of 2p3s by Molmil
Crystal structure of a thermostable mutant of Bacillus subtilis Adenylate Kinase (G214R/Q199R)
分子名称: Adenylate kinase, BIS(ADENOSINE)-5'-PENTAPHOSPHATE, MAGNESIUM ION, ...
著者Counago, R, Wilson, C.J, Myers, J, Wu, G, Shamoo, Y.
登録日2007-03-09
公開日2008-01-22
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal structure of a thermostable mutant of Bacillus subtilis Adenylate Kinase (G214R/Q199R)
To be Published
5UDV
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BU of 5udv by Molmil
LarE, a sulfur transferase involved in synthesis of the cofactor for lactate racemase, in complex with iron
分子名称: FE (III) ION, Lactate racemization operon protein LarE, PHOSPHATE ION, ...
著者Fellner, M, Desguin, B, Hausinger, R.P, Hu, J.
登録日2016-12-28
公開日2017-08-23
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.621 Å)
主引用文献Structural insights into the catalytic mechanism of a sacrificial sulfur insertase of the N-type ATP pyrophosphatase family, LarE.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
4U92
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BU of 4u92 by Molmil
Crystal structure of a DNA/Ba2+ G-quadruplex containing a water-mediated C-tetrad
分子名称: BARIUM ION, DNA (5'-D(*CP*CP*AP*KP*GP*CP*GP*TP*GP*G)-3'), MAGNESIUM ION
著者Paukstelis, P.J, Zhang, D, Huang, T, Lukeman, P.
登録日2014-08-05
公開日2014-11-26
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Crystal structure of a DNA/Ba2+ G-quadruplex containing a water-mediated C-tetrad.
Nucleic Acids Res., 42, 2014
7O75
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BU of 7o75 by Molmil
Yeast RNA polymerase II transcription pre-initiation complex with open promoter DNA
分子名称: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, DNA-directed RNA polymerase II subunit RPB1, ...
著者Schilbach, S, Aibara, S, Dienemann, C, Grabbe, F, Cramer, P.
登録日2021-04-13
公開日2021-06-16
最終更新日2024-07-10
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Structure of RNA polymerase II pre-initiation complex at 2.9 angstrom defines initial DNA opening.
Cell, 184, 2021
7O72
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BU of 7o72 by Molmil
Yeast RNA polymerase II transcription pre-initiation complex with closed promoter DNA
分子名称: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, DNA-directed RNA polymerase II subunit RPB1, ...
著者Schilbach, S, Aibara, S, Dienemann, C, Grabbe, F, Cramer, P.
登録日2021-04-12
公開日2021-06-16
最終更新日2024-07-10
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Structure of RNA polymerase II pre-initiation complex at 2.9 angstrom defines initial DNA opening.
Cell, 184, 2021
4TV1
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BU of 4tv1 by Molmil
Crystal structure of hERa-LBD (Y537S) in complex with propylparaben
分子名称: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, Estrogen receptor, ...
著者Delfosse, V, Grimaldi, M, Bourguet, W.
登録日2014-06-25
公開日2015-01-28
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献A structural perspective on nuclear receptors as targets of environmental compounds.
Acta Pharmacol.Sin., 36, 2015
4TX6
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BU of 4tx6 by Molmil
AfChiA1 in complex with compound 1
分子名称: 3-(2-methoxyphenyl)-6-methyl[1,2]oxazolo[5,4-d]pyrimidin-4(5H)-one, Class III chitinase ChiA1, PHOSPHATE ION
著者van Aalten, D.M.F.
登録日2014-07-02
公開日2014-08-06
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Screening-based discovery of Aspergillus fumigatus plant-type chitinase inhibitors
FEBS Lett, 588, 2014
4TXN
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BU of 4txn by Molmil
Crystal structure of uridine phosphorylase from Schistosoma mansoni in complex with 5-fluorouracil
分子名称: 5-FLUOROURACIL, SULFATE ION, Uridine phosphorylase
著者Marinho, A, Torini, J, Romanello, L, Cassago, A, DeMarco, R, Brandao-Neto, J, Pereira, H.M.
登録日2014-07-03
公開日2015-10-14
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Analysis of two Schistosoma mansoni uridine phosphorylases isoforms suggests the emergence of a protein with a non-canonical function.
Biochimie, 125, 2016
4TUZ
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BU of 4tuz by Molmil
Crystal structure of hERa-LBD (Y537S) in complex with alpha-zearalenol
分子名称: (3S,7R,11E)-7,14,16-trihydroxy-3-methyl-3,4,5,6,7,8,9,10-octahydro-1H-2-benzoxacyclotetradecin-1-one, 1,2-ETHANEDIOL, Estrogen receptor, ...
著者Delfosse, V, Grimaldi, M, Bourguet, W.
登録日2014-06-25
公開日2015-01-28
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献A structural perspective on nuclear receptors as targets of environmental compounds.
Acta Pharmacol. Sin., 36, 2015
5UDU
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BU of 5udu by Molmil
LarE, a sulfur transferase involved in synthesis of the cofactor for lactate racemase, in complex with manganese
分子名称: Lactate racemization operon protein LarE, MANGANESE (II) ION, PHOSPHATE ION, ...
著者Fellner, M, Desguin, B, Hausinger, R.P, Hu, J.
登録日2016-12-28
公開日2017-08-23
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.792 Å)
主引用文献Structural insights into the catalytic mechanism of a sacrificial sulfur insertase of the N-type ATP pyrophosphatase family, LarE.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5UDS
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BU of 5uds by Molmil
LarE, a sulfur transferase involved in synthesis of the cofactor for lactate racemase, in complex with MgATP
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Lactate racemization operon protein LarE, MAGNESIUM ION, ...
著者Fellner, M, Desguin, B, Hausinger, R.P, Hu, J.
登録日2016-12-28
公開日2017-08-23
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.37 Å)
主引用文献Structural insights into the catalytic mechanism of a sacrificial sulfur insertase of the N-type ATP pyrophosphatase family, LarE.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
7NH4
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BU of 7nh4 by Molmil
Co-Crystal Structure of Akt1 in Complex with Covalent-Allosteric Akt Inhibitor 3
分子名称: ACETATE ION, RAC-alpha serine/threonine-protein kinase, ~{N}-[3-[1-[[4-[5-(hydroxymethyl)-3-phenyl-pyridin-2-yl]phenyl]methyl]piperidin-4-yl]-2-oxidanylidene-1~{H}-benzimidazol-5-yl]propanamide
著者Landel, I, Mueller, M.P, Rauh, D.
登録日2021-02-10
公開日2021-09-08
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Cellular model system to dissect the isoform-selectivity of Akt inhibitors.
Nat Commun, 12, 2021
7NH5
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BU of 7nh5 by Molmil
Co-Crystal Structure of Akt1 in Complex with Covalent-Allosteric Akt Inhibitor 6
分子名称: ACETATE ION, RAC-alpha serine/threonine-protein kinase, ~{N}-methyl-6-[4-[[4-[2-oxidanylidene-6-(propanoylamino)-3~{H}-benzimidazol-1-yl]piperidin-1-yl]methyl]phenyl]-5-phenyl-pyridine-3-carboxamide
著者Landel, I, Mueller, M.P, Rauh, D.
登録日2021-02-10
公開日2021-09-08
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Cellular model system to dissect the isoform-selectivity of Akt inhibitors.
Nat Commun, 12, 2021
5UYM
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BU of 5uym by Molmil
70S ribosome bound with cognate ternary complex base-paired to A site codon, closed 30S (Structure III)
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Loveland, A.B, Demo, G, Grigorieff, N, Korostelev, A.A.
登録日2017-02-24
公開日2017-06-07
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Ensemble cryo-EM elucidates the mechanism of translation fidelity
Nature, 546, 2017
7OP1
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BU of 7op1 by Molmil
Cryo-EM structure of P5B-ATPase E2PiAlF/SPM
分子名称: Cation-transporting ATPase, MAGNESIUM ION, SPERMINE, ...
著者Li, P, Gourdon, P.
登録日2021-05-28
公開日2021-06-30
最終更新日2024-07-17
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Structure and transport mechanism of P5B-ATPases.
Nat Commun, 12, 2021
7OP5
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BU of 7op5 by Molmil
Cryo-EM structure of P5B-ATPase E2P
分子名称: BERYLLIUM TRIFLUORIDE ION, MAGNESIUM ION, P5B-ATPase
著者Li, P, Gourdon, P.
登録日2021-05-29
公開日2021-06-30
最終更新日2024-07-17
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Structure and transport mechanism of P5B-ATPases.
Nat Commun, 12, 2021
5V8I
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BU of 5v8i by Molmil
Thermus thermophilus 70S ribosome lacking ribosomal protein uS17
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 16S Ribosomal RNA, 23S Ribosomal RNA, ...
著者Gregory, S.T, Jogl, G.
登録日2017-03-22
公開日2018-03-28
最終更新日2025-03-19
実験手法X-RAY DIFFRACTION (3.25 Å)
主引用文献Structural robustness of the ribosome inferred from X-ray crystal structures of the 30S ribosomal subunit and the 70S ribosome lacking ribosomal protein uS17
To be published
4R7Q
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BU of 4r7q by Molmil
The structure of a sensor domain of a histidine kinase from Vibrio cholerae O1 biovar eltor str. N16961
分子名称: ACETATE ION, GLYCEROL, SULFATE ION, ...
著者Tan, K, Zhou, M, Kwon, K, Anderson, W.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2014-08-28
公開日2014-09-10
最終更新日2024-11-20
実験手法X-RAY DIFFRACTION (1.981 Å)
主引用文献Sensor Domain of Histidine Kinase VxrA of Vibrio cholerae - A Hairpin-swapped Dimer and its Conformational Change.
J.Bacteriol., 203, 2021
7OOL
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BU of 7ool by Molmil
Crystal structure of a Candidatus photodesmus katoptron thioredoxin chimera containing an ancestral loop
分子名称: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, GLYCEROL, ...
著者Gavira, J.A, Ibarra-Molero, B, Gamiz-Arco, G, Risso, V, Sanchez-Ruiz, J.M.
登録日2021-05-28
公開日2021-11-10
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Combining Ancestral Reconstruction with Folding-Landscape Simulations to Engineer Heterologous Protein Expression.
J.Mol.Biol., 433, 2021
5VP2
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BU of 5vp2 by Molmil
Crystal structure of the Thermus thermophilus 70S ribosome in complex with madumycin II and bound to mRNA and A-, P- and E-site tRNAs at 2.8A resolution
分子名称: 16S ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ...
著者Osterman, I.A, Khabibullina, N.F, Komarova, E.S, Kasatsky, P, Kartsev, V.G, Bogdanov, A.A, Dontsova, O.A, Konevega, A.L, Sergiev, P.V, Polikanov, Y.S.
登録日2017-05-04
公開日2017-06-28
最終更新日2025-03-12
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Madumycin II inhibits peptide bond formation by forcing the peptidyl transferase center into an inactive state.
Nucleic Acids Res., 45, 2017
5VPO
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BU of 5vpo by Molmil
The 70S P-site ASL SufA6 complex
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
著者Hong, S, Sunita, S, Dunkle, J.A, Maehigashi, T, Dunham, C.M.
登録日2017-05-05
公開日2018-09-26
最終更新日2024-11-20
実験手法X-RAY DIFFRACTION (3.34 Å)
主引用文献Mechanism of tRNA-mediated +1 ribosomal frameshifting.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
7CPV
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BU of 7cpv by Molmil
Cryo-EM structure of 80S ribosome from mouse testis
分子名称: 40S ribosomal protein S10, 40S ribosomal protein S11, 40S ribosomal protein S13, ...
著者Huo, Y.G, He, X, Jiang, T, Qin, Y, Guo, X.J, Sha, J.H.
登録日2020-08-08
公開日2022-02-02
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (3.03 Å)
主引用文献A male germ-cell-specific ribosome controls male fertility.
Nature, 612, 2022
7CPU
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BU of 7cpu by Molmil
Cryo-EM structure of 80S ribosome from mouse kidney
分子名称: 40S ribosomal protein S10, 40S ribosomal protein S11, 40S ribosomal protein S13, ...
著者Huo, Y.G, He, X, Jiang, T, Qin, Y, Guo, X.J, Sha, J.H.
登録日2020-08-08
公開日2022-02-02
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (2.82 Å)
主引用文献A male germ-cell-specific ribosome controls male fertility.
Nature, 612, 2022
7OB9
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BU of 7ob9 by Molmil
Cryo-EM structure of human RNA Polymerase I in elongation state
分子名称: DNA non-template strand, DNA template strand, DNA-directed RNA polymerase I subunit RPA1, ...
著者Misiaszek, A.D, Girbig, M, Mueller, C.W.
登録日2021-04-21
公開日2021-12-08
最終更新日2024-07-10
実験手法ELECTRON MICROSCOPY (2.7 Å)
主引用文献Cryo-EM structures of human RNA polymerase I.
Nat.Struct.Mol.Biol., 28, 2021

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