4TV1
Crystal structure of hERa-LBD (Y537S) in complex with propylparaben
Summary for 4TV1
| Entry DOI | 10.2210/pdb4tv1/pdb |
| Related | 4MG9 |
| Descriptor | Estrogen receptor, Nuclear receptor coactivator 1, propyl 4-hydroxybenzoate, ... (8 entities in total) |
| Functional Keywords | nuclear hormone receptor, ligand binding domain, endocrine disruptor, environmental compound, hormone receptor |
| Biological source | Homo sapiens (Human) More |
| Cellular location | Isoform 1: Nucleus . Isoform 3: Nucleus. Nucleus: P03372 P03372 |
| Total number of polymer chains | 4 |
| Total formula weight | 61670.49 |
| Authors | Delfosse, V.,Grimaldi, M.,Bourguet, W. (deposition date: 2014-06-25, release date: 2015-01-28, Last modification date: 2023-12-20) |
| Primary citation | Delfosse, V.,Maire, A.L.,Balaguer, P.,Bourguet, W. A structural perspective on nuclear receptors as targets of environmental compounds. Acta Pharmacol.Sin., 36:88-101, 2015 Cited by PubMed: 25500867DOI: 10.1038/aps.2014.133 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.85 Å) |
Structure validation
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