4TUZ

Crystal structure of hERa-LBD (Y537S) in complex with alpha-zearalenol

Summary for 4TUZ

• Entry DOI: 10.2210/pdb4tuz/pdb
• Related: 4MG8
• Descriptor: Estrogen receptor, Nuclear receptor coactivator 1, (3S,7R,11E)-7,14,16-trihydroxy-3-methyl-3,4,5,6,7,8,9,10-octahydro-1H-2-benzoxacyclotetradecin-1-one, ... (7 entities in total)
• Functional Keywords: nuclear hormone receptor ligand binding domain endocrine disruptor environmental compound, nuclear protein
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 4
• Total formula weight: 62473.47

Authors

Delfosse, V.,Grimaldi, M.,Bourguet, W. (deposition date: 2014-06-25, release date: 2015-01-28, Last modification date: 2023-12-20)

• Primary citation: Delfosse, V.,Maire, A.L.,Balaguer, P.,Bourguet, W.; A structural perspective on nuclear receptors as targets of environmental compounds.; Acta Pharmacol. Sin., 36:88-101, 2015; PubMed: 25500867; DOI: 10.1038/aps.2014.133

Experimental method

X-RAY DIFFRACTION (1.9 Å)