4TUZ
Crystal structure of hERa-LBD (Y537S) in complex with alpha-zearalenol
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 13 |
| Details | binding site for residue 36J A 601 |
| Chain | Residue |
| A | LEU346 |
| A | LEU428 |
| A | GLY521 |
| A | HIS524 |
| A | LEU525 |
| A | LEU349 |
| A | ALA350 |
| A | GLU353 |
| A | LEU387 |
| A | MET388 |
| A | LEU391 |
| A | PHE404 |
| A | MET421 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | binding site for residue GOL A 602 |
| Chain | Residue |
| A | TYR331 |
| A | ASN407 |
| A | LEU408 |
| A | LEU409 |
| A | GLN414 |
| site_id | AC3 |
| Number of Residues | 2 |
| Details | binding site for residue EDO A 603 |
| Chain | Residue |
| A | GLU323 |
| A | TRP393 |
| site_id | AC4 |
| Number of Residues | 7 |
| Details | binding site for residue GOL A 604 |
| Chain | Residue |
| A | GLU353 |
| A | GLY390 |
| A | ARG394 |
| A | PHE445 |
| A | LYS449 |
| A | HOH731 |
| A | HOH754 |
| site_id | AC5 |
| Number of Residues | 12 |
| Details | binding site for residue 36J B 601 |
| Chain | Residue |
| B | LEU346 |
| B | LEU349 |
| B | ALA350 |
| B | GLU353 |
| B | LEU387 |
| B | MET388 |
| B | LEU391 |
| B | MET421 |
| B | LEU428 |
| B | GLY521 |
| B | HIS524 |
| B | LEU525 |
| site_id | AC6 |
| Number of Residues | 1 |
| Details | binding site for residue EDO B 602 |
| Chain | Residue |
| B | TRP393 |
| site_id | AC7 |
| Number of Residues | 3 |
| Details | binding site for residue GOL B 603 |
| Chain | Residue |
| B | GLN441 |
| B | GLU444 |
| B | ALA493 |
| site_id | AC8 |
| Number of Residues | 7 |
| Details | binding site for residue GOL B 604 |
| Chain | Residue |
| B | GLU323 |
| B | ILE326 |
| B | GLY390 |
| B | ARG394 |
| B | PHE445 |
| B | LYS449 |
| B | HOH730 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 6 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"9338790","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"9600906","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1A52","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1ERE","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"Phosphotyrosine; by Tyr-kinases","evidences":[{"source":"PubMed","id":"7539106","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | Lipidation: {"description":"S-palmitoyl cysteine","evidences":[{"evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 8 |
| Details | Motif: {"description":"LXXLL motif 4"} |
| Chain | Residue | Details |
