1IGF
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4ADJ
| Crystal structure of the Rubella virus glycoprotein E1 in its post-fusion form crystallized in presence of 1mM of calcium acetate | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, CALCIUM ION, ... | 著者 | DuBois, R.M, Vaney, M.C, Tortorici, M.A, Al Kurdi, R, Barba-Spaeth, G, Rey, F.A. | 登録日 | 2011-12-26 | 公開日 | 2013-01-09 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.94 Å) | 主引用文献 | Functional and Evolutionary Insight from the Crystal Structure of Rubella Virus Protein E1. Nature, 493, 2013
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1DRB
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1IPH
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5NDA
| NMR Structural Characterisation of Pharmaceutically Relevant Proteins Obtained Through a Novel Recombinant Production: The Case of The Pulmonary Surfactant Polypeptide C Analogue rSP-C33Leu. | 分子名称: | rSP-C33Leu -RECOMBINANT PULMONARY SURFACTANT-ASSOCIATED POLYPEPTIDE C ANALOGUE- | 著者 | Venturi, L, Pioselli, B, Johansson, J, Rising, A, Kronqvist, N, Nordling, K. | 登録日 | 2017-03-08 | 公開日 | 2017-06-07 | 最終更新日 | 2024-06-19 | 実験手法 | SOLUTION NMR | 主引用文献 | Efficient protein production inspired by how spiders make silk. Nat Commun, 8, 2017
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5O7E
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5OAE
| Crystal Structure of tyrosinase from Bacillus megaterium with SVF inhibitor in the active site | 分子名称: | 1-[4-[(4-fluorophenyl)methyl]piperidin-1-yl]ethanone, COPPER (II) ION, Tyrosinase | 著者 | Deri, B, Gitto, R, Pazy Benhar, Y, Fishman, A. | 登録日 | 2017-06-21 | 公開日 | 2018-04-25 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Targeting Tyrosinase: Development and Structural Insights of Novel Inhibitors Bearing Arylpiperidine and Arylpiperazine Fragments. J. Med. Chem., 61, 2018
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5HX6
| Crystal structure of RIP1 kinase with a benzo[b][1,4]oxazepin-4-one | 分子名称: | 5-benzyl-N-[(3S)-5-methyl-4-oxo-2,3,4,5-tetrahydro-1,5-benzoxazepin-3-yl]-1,2-oxazole-3-carboxamide, Receptor-interacting serine/threonine-protein kinase 1 | 著者 | Campobasso, N, Ward, P. | 登録日 | 2016-01-29 | 公開日 | 2016-03-02 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (2.23 Å) | 主引用文献 | DNA-Encoded Library Screening Identifies Benzo[b][1,4]oxazepin-4-ones as Highly Potent and Monoselective Receptor Interacting Protein 1 Kinase Inhibitors. J.Med.Chem., 59, 2016
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1AYL
| PHOSPHOENOLPYRUVATE CARBOXYKINASE | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, OXALATE ION, ... | 著者 | Tari, L.W, Pugazenthi, U, Goldie, H, Delbaere, L.T.J. | 登録日 | 1995-12-07 | 公開日 | 1997-01-11 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Snapshot of an enzyme reaction intermediate in the structure of the ATP-Mg2+-oxalate ternary complex of Escherichia coli PEP carboxykinase. Nat.Struct.Biol., 3, 1996
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3HKS
| Crystal structure of eukaryotic translation initiation factor eIF-5A2 from Arabidopsis thaliana | 分子名称: | 1,2-ETHANEDIOL, Eukaryotic translation initiation factor 5A-2 | 著者 | Teng, Y.B, He, Y.X, Jiang, Y.L, Chen, Y.X, Zhou, C.Z. | 登録日 | 2009-05-25 | 公開日 | 2009-09-29 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Crystal structure of Arabidopsis translation initiation factor eIF-5A2 Proteins, 77, 2009
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5KX4
| Structure of SALO | 分子名称: | 10.7 kDa salivary protein | 著者 | Asojo, O.A. | 登録日 | 2016-07-20 | 公開日 | 2016-07-27 | 最終更新日 | 2017-11-22 | 実験手法 | X-RAY DIFFRACTION (1.94 Å) | 主引用文献 | Structure of SALO, a leishmaniasis vaccine candidate from the sand fly Lutzomyia longipalpis. PLoS Negl Trop Dis, 11, 2017
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5D6E
| Structure of human methionine aminopeptidase 2 with covalent spiroepoxytriazole inhibitor (-)-31b | 分子名称: | (4R,7S)-7-hydroxy-1-(4-methoxybenzyl)-7-methyl-4,5,6,7-tetrahydro-1H-benzotriazol-4-yl propan-2-ylcarbamate, COBALT (II) ION, Methionine aminopeptidase 2, ... | 著者 | Janowski, R, Miller, A.K, Niessing, D. | 登録日 | 2015-08-12 | 公開日 | 2016-01-13 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.49 Å) | 主引用文献 | Spiroepoxytriazoles Are Fumagillin-like Irreversible Inhibitors of MetAP2 with Potent Cellular Activity. Acs Chem.Biol., 11, 2016
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7X39
| Structure of CIZ1 bound ERH | 分子名称: | Enhancer of rudimentary homolog,Cip1-interacting zinc finger protein | 著者 | Wang, X, Xu, C. | 登録日 | 2022-02-28 | 公開日 | 2022-08-31 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | 主引用文献 | Molecular basis for the recognition of CIZ1 by ERH. Febs J., 290, 2023
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5LAR
| Crystal structure of p38 alpha MAPK14 in complex with VPC00628 | 分子名称: | 5-azanyl-~{N}-[[4-[[(2~{S})-1-azanyl-4-cyclohexyl-1-oxidanylidene-butan-2-yl]carbamoyl]phenyl]methyl]-1-phenyl-pyrazole-4-carboxamide, Mitogen-activated protein kinase 14 | 著者 | Chaikuad, A, Petersen, L.K, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Knapp, S, Structural Genomics Consortium (SGC) | 登録日 | 2016-06-14 | 公開日 | 2016-07-06 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Novel p38alpha MAP kinase inhibitors identified from yoctoReactor DNA-encoded small molecule library Medchemcomm, 7, 2016
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1XSO
| THREE-DIMENSIONAL STRUCTURE OF XENOPUS LAEVIS CU,ZN SUPEROXIDE DISMUTASE B DETERMINED BY X-RAY CRYSTALLOGRAPHY AT 1.5 ANGSTROMS RESOLUTION | 分子名称: | COPPER (II) ION, COPPER,ZINC SUPEROXIDE DISMUTASE, ZINC ION | 著者 | Djinovic Carugo, K, Coda, A, Battistoni, A, Carri, M.T, Polticelli, F, Desideri, A, Rotilio, G, Wilson, K.S, Bolognesi, M. | 登録日 | 1995-03-14 | 公開日 | 1995-07-10 | 最終更新日 | 2019-08-14 | 実験手法 | X-RAY DIFFRACTION (1.49 Å) | 主引用文献 | Three-dimensional structure of Xenopus laevis Cu,Zn superoxide dismutase b determined by X-ray crystallography at 1.5 A resolution. Acta Crystallogr.,Sect.D, 52, 1996
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4RME
| Crystal structure of human Retinoid X receptor alpha ligand binding domain complex with 9cUAB111 and coactivator peptide GRIP-1 | 分子名称: | (2E,4E,6Z,8E)-3,7-dimethyl-8-[2-(3-methylbutyl)-3-(propan-2-yl)cyclohex-2-en-1-ylidene]octa-2,4,6-trienoic acid, Nuclear receptor coactivator 2, Retinoic acid receptor RXR-alpha | 著者 | Xia, G, Muccio, D.D. | 登録日 | 2014-10-21 | 公開日 | 2015-09-16 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Conformationally Defined Rexinoids and Their Efficacy in the Prevention of Mammary Cancers. J.Med.Chem., 58, 2015
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4B3V
| Crystal structure of the Rubella virus glycoprotein E1 in its post-fusion form crystallized in presence of 20mM of Calcium Acetate | 分子名称: | 2-acetamido-2-deoxy-beta-D-galactopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, ... | 著者 | Vaney, M.C, DuBois, R.M, Tortorici, M.A, Rey, F.A. | 登録日 | 2012-07-26 | 公開日 | 2013-01-09 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.98 Å) | 主引用文献 | Functional and Evolutionary Insight from the Crystal Structure of Rubella Virus Protein E1. Nature, 493, 2013
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6NAN
| NMR structure determination of Ixolaris and Factor X interaction reveals a noncanonical mechanism of Kunitz inhibition | 分子名称: | Ixolaris | 著者 | De Paula, V.S, Sgourakis, N.G, Francischetti, I.M.B, Almeida, F.C.L, Monteiro, R.Q, Valente, A.P. | 登録日 | 2018-12-06 | 公開日 | 2019-06-12 | 最終更新日 | 2023-06-14 | 実験手法 | SOLUTION NMR | 主引用文献 | NMR structure determination of Ixolaris and factor X(a) interaction reveals a noncanonical mechanism of Kunitz inhibition. Blood, 134, 2019
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1MRB
| THREE-DIMENSIONAL STRUCTURE OF RABBIT LIVER CD7 METALLOTHIONEIN-2A IN AQUEOUS SOLUTION DETERMINED BY NUCLEAR MAGNETIC RESONANCE | 分子名称: | CADMIUM ION, CD7 METALLOTHIONEIN-2A | 著者 | Braun, W, Arseniev, A, Schultze, P, Woergoetter, E, Wagner, G, Vasak, M, Kaegi, J.H.R, Wuthrich, K. | 登録日 | 1990-05-14 | 公開日 | 1991-04-15 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | Three-dimensional structure of rabbit liver [Cd7]metallothionein-2a in aqueous solution determined by nuclear magnetic resonance. J.Mol.Biol., 201, 1988
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4RMD
| Crystal structure of human Retinoid X receptor alpha ligand binding domain complex with 9cUAB110 and coactivator peptide GRIP-1 | 分子名称: | (2E,4E,6Z,8E)-8-[3-cyclopropyl-2-(3-methylbutyl)cyclohex-2-en-1-ylidene]-3,7-dimethylocta-2,4,6-trienoic acid, Nuclear receptor coactivator 2, Retinoic acid receptor RXR-alpha | 著者 | Xia, G, Muccio, D.D. | 登録日 | 2014-10-21 | 公開日 | 2015-09-23 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Conformationally Defined Rexinoids and Their Efficacy in the Prevention of Mammary Cancers. J.Med.Chem., 58, 2015
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4RMC
| Crystal Structure of human retinoid X receptor alpha-ligand binding domain complex with 9cUAB76 and the coactivator peptide GRIP-1 | 分子名称: | (3S,7S,8E)-8-[3-ethyl-2-(3-methylbutyl)cyclohex-2-en-1-ylidene]-3,7-dimethyloctanoic acid, Nuclear receptor coactivator 2, Retinoic acid receptor RXR-alpha | 著者 | Xia, G, Muccio, D.D. | 登録日 | 2014-10-21 | 公開日 | 2015-09-16 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Conformationally Defined Rexinoids and Their Efficacy in the Prevention of Mammary Cancers. J.Med.Chem., 58, 2015
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5L8S
| The crystal structure of a cold-adapted acylaminoacyl peptidase reveals a novel quaternary architecture based on the arm-exchange mechanism | 分子名称: | Amino acyl peptidase, SULFATE ION | 著者 | Brocca, S, Ferrari, C, Barbiroli, A, Pesce, A, Lotti, M, Nardini, M. | 登録日 | 2016-06-08 | 公開日 | 2016-11-16 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | A bacterial acyl aminoacyl peptidase couples flexibility and stability as a result of cold adaptation. FEBS J., 283, 2016
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7Y80
| CryoEM structure of type III-E CRISPR Craspase gRAMP-crRNA binary complex | 分子名称: | MAGNESIUM ION, RAMP superfamily protein, ZINC ION, ... | 著者 | Zhang, J.T, Cui, N, Huang, H.D, Jia, N. | 登録日 | 2022-06-22 | 公開日 | 2022-12-14 | 最終更新日 | 2024-05-08 | 実験手法 | ELECTRON MICROSCOPY (2.71 Å) | 主引用文献 | Structural basis for the non-self RNA-activated protease activity of the type III-E CRISPR nuclease-protease Craspase. Nat Commun, 13, 2022
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5D6F
| Structure of human methionine aminopeptidase-2 complexed with spiroepoxytriazole inhibitor (+)-31b | 分子名称: | (4S,7R)-7-hydroxy-1-(4-methoxybenzyl)-7-methyl-4,5,6,7-tetrahydro-1H-benzotriazol-4-yl propan-2-ylcarbamate, 1,2-ETHANEDIOL, COBALT (II) ION, ... | 著者 | Janowski, R, Miller, A.K, Niessing, D. | 登録日 | 2015-08-12 | 公開日 | 2016-01-13 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | Spiroepoxytriazoles Are Fumagillin-like Irreversible Inhibitors of MetAP2 with Potent Cellular Activity. Acs Chem.Biol., 11, 2016
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1BF4
| CHROMOSOMAL DNA-BINDING PROTEIN SSO7D/D(GCGAACGC) COMPLEX | 分子名称: | DNA (5'-D(*GP*CP*GP*AP*AP*CP*GP*C)-3'), DNA (5'-D(*GP*CP*GP*TP*5IUP*CP*GP*C)-3'), PROTEIN (CHROMOSOMAL PROTEIN SSO7D) | 著者 | Su, S, Gao, Y.-G, Robinson, H, Padmanabhan, S, Lim, L, Shriver, J.W, Wang, A.H.-J. | 登録日 | 1998-05-27 | 公開日 | 1999-11-10 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | The crystal structure of the hyperthermophile chromosomal protein Sso7d bound to DNA. Nat.Struct.Biol., 5, 1998
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