PDB: 97138 件ウェブページステータス検索Chemie searchBIRD

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8ETD	Crystal Structure of Schizosaccharomyces pombe Rho1 分子名称: GTP-binding protein rho1, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION 著者 Huang, Q, Xie, J, Seetharaman, J. 登録日 2022-10-16 公開日 2022-12-07 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.78 Å) 主引用文献 Crystal Structure of Schizosaccharomyces pombe Rho1 Reveals Its Evolutionary Relationship with Other Rho GTPases. Biology (Basel), 11, 2022
3EHX	Crystal structure of the catalytic domain of human MMP12 complexed with the inhibitor (R)-2-(biphenyl-4-ylsulfonamido)-4-methylpentanoic acid 分子名称: CALCIUM ION, Macrophage metalloelastase, N-(biphenyl-4-ylsulfonyl)-D-leucine, ... 著者 Calderone, V. 登録日 2008-09-15 公開日 2009-05-19 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Biotin-tagged probes for MMP expression and activation: design, synthesis, and binding properties Bioconjug.Chem., 20, 2009
1RFN	HUMAN COAGULATION FACTOR IXA IN COMPLEX WITH P-AMINO BENZAMIDINE 分子名称: CALCIUM ION, P-AMINO BENZAMIDINE, PROTEIN (COAGULATION FACTOR IX), ... 著者 Hopfner, K.-P, Lang, A, Karcher, A, Sichler, K, Kopetzki, E, Brandstetter, H, Huber, R, Bode, W, Engh, R.A. 登録日 1999-04-19 公開日 1999-09-01 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Coagulation factor IXa: the relaxed conformation of Tyr99 blocks substrate binding. Structure Fold.Des., 7, 1999
4GZA	Complex of mouse Plexin A2 - Semaphorin 3A - Neuropilin-1 分子名称: CALCIUM ION, Neuropilin-1, Plexin-A2, ... 著者 Janssen, B.J.C, Malinauskas, T, Siebold, C, Jones, E.Y. 登録日 2012-09-06 公開日 2012-10-17 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (7 Å) 主引用文献 Neuropilins lock secreted semaphorins onto plexins in a ternary signaling complex. Nat.Struct.Mol.Biol., 19, 2012
7SYP	Structure of the wt IRES and 40S ribosome binary complex, open conformation. Structure 10(wt) 分子名称: 18S rRNA, HCV IRES, HCV IRES partially loaded mRNA portion, ... 著者 Brown, Z.P, Abaeva, I.S, De, S, Hellen, C.U.T, Pestova, T.V, Frank, J. 登録日 2021-11-25 公開日 2022-07-27 最終更新日 2022-08-24 実験手法 ELECTRON MICROSCOPY (4 Å) 主引用文献 Molecular architecture of 40S translation initiation complexes on the hepatitis C virus IRES. Embo J., 41, 2022
6TP5	Crystal structure of human Transmembrane prolyl 4-hydroxylase 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, CHLORIDE ION, ... 著者 Myllykoski, M, Sutinen, A, Koski, M.K, Kallio, J.P, Raasakka, A, Myllyharju, J, Wierenga, R.K, Koivunen, P. 登録日 2019-12-12 公開日 2020-12-23 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Structure of transmembrane prolyl 4-hydroxylase reveals unique organization of EF and dioxygenase domains. J.Biol.Chem., 296, 2020
1DRE	DIHYDROFOLATE REDUCTASE COMPLEXED WITH METHOTREXATE AND NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE (OXIDIZED FORM) 分子名称: DIHYDROFOLATE REDUCTASE, METHOTREXATE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE 著者 Sawaya, M.R, Kraut, J. 登録日 1996-11-28 公開日 1997-03-12 最終更新日 2023-08-09 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Loop and subdomain movements in the mechanism of Escherichia coli dihydrofolate reductase: crystallographic evidence. Biochemistry, 36, 1997
1MHJ	SOLUTION STRUCTURE OF THE SUPERACTIVE MONOMERIC DES-[PHE(B25)] HUMAN INSULIN MUTANT. ELUCIDATION OF THE STRUCTURAL BASIS FOR THE MONOMERIZATION OF THE DES-[PHE(B25)] INSULIN AND THE DIMERIZATION OF NATIVE INSULIN 分子名称: INSULIN 著者 Jorgensen, A.M.M, Olsen, H.B, Led, J.J, Balschmidt, P. 登録日 1994-11-30 公開日 1995-10-15 最終更新日 2017-11-29 実験手法 SOLUTION NMR 主引用文献 Solution structure of the superactive monomeric des-[Phe(B25)] human insulin mutant: elucidation of the structural basis for the monomerization of des-[Phe(B25)] insulin and the dimerization of native insulin. J.Mol.Biol., 257, 1996
3EHY	Crystal structure of the catalytic domain of human MMP12 complexed with the inhibitor (R)-2-(4-methoxyphenylsulfonamido)propanoic acid 分子名称: CALCIUM ION, Macrophage metalloelastase, N-[(4-methoxyphenyl)sulfonyl]-D-alanine, ... 著者 Calderone, V. 登録日 2008-09-15 公開日 2009-05-19 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Biotin-tagged probes for MMP expression and activation: design, synthesis, and binding properties Bioconjug.Chem., 20, 2009
7VQX	Cryo-EM structure of human vasoactive intestinal polypeptide receptor 2 (VIP2R) in complex with PACAP27 and Gs 分子名称: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, ... 著者 Xu, Y.N, Feng, W.B, Zhou, Q.T, Liang, A.Y, Li, J, Dai, A.T, Zhao, F.H, Yan, J.H, Chen, C.W, Li, H, Zhao, L.H, Xia, T, Jiang, Y, Xu, H.E, Yang, D.H, Wang, M.W. 登録日 2021-10-21 公開日 2022-05-18 実験手法 ELECTRON MICROSCOPY (2.74 Å) 主引用文献 A distinctive ligand recognition mechanism by the human vasoactive intestinal polypeptide receptor 2. Nat Commun, 13, 2022
5CR0	Human DNA polymerase lambda L431A mutant- MgdCTP binary and complex with 6 paired DNA 分子名称: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, DNA (5'-D(*CP*AP*GP*TP*AP*C)-3'), DNA (5'-D(P*GP*TP*AP*CP*TP*G)-3'), ... 著者 Liu, M.S, Tsai, M.D. 登録日 2015-07-22 公開日 2016-02-24 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.75 Å) 主引用文献 Structural Mechanism for the Fidelity Modulation of DNA Polymerase lambda J.Am.Chem.Soc., 138, 2016
1OI6	Structure determination of the TMP-complex of EvaD 分子名称: GLYCEROL, PCZA361.16, THYMIDINE-5'-PHOSPHATE 著者 Merkel, A.B, Naismith, J.H. 登録日 2003-06-09 公開日 2004-06-03 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 The Position of a Key Tyrosine in Dtdp-4-Keto-6-Deoxy-D-Glucose-5-Epimerase (Evad) Alters the Substrate Profile for This Rmlc-Like Enzyme J.Biol.Chem., 279, 2004
1OXY	CRYSTALLOGRAPHIC ANALYSIS OF OXYGENATED AND DEOXYGENATED STATES OF ARTHROPOD HEMOCYANIN SHOWS UNUSUAL DIFFERENCES 分子名称: COPPER (II) ION, HEMOCYANIN (SUBUNIT TYPE II), OXYGEN MOLECULE 著者 Ton-that, H, Magnus, K. 登録日 1995-01-06 公開日 1995-02-27 最終更新日 2024-06-05 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Crystallographic analysis of oxygenated and deoxygenated states of arthropod hemocyanin shows unusual differences. Proteins, 19, 1994
1RUV	RIBONUCLEASE A-URIDINE VANADATE COMPLEX: HIGH RESOLUTION RESOLUTION X-RAY STRUCTURE (1.3 A) 分子名称: RIBONUCLEASE A, TERTIARY-BUTYL ALCOHOL, URIDINE-2',3'-VANADATE 著者 Ladner, J.E, Wladkowski, B, Svensson, L.A, Sjolin, L, Gilliland, G.L. 登録日 1995-07-27 公開日 1997-04-01 最終更新日 2024-06-05 実験手法 X-RAY DIFFRACTION (1.25 Å) 主引用文献 X-ray structure of a ribonuclease A-uridine vanadate complex at 1.3 A resolution. Acta Crystallogr.,Sect.D, 53, 1997
1HOM	DETERMINATION OF THE THREE-DIMENSIONAL STRUCTURE OF THE ANTENNAPEDIA HOMEODOMAIN FROM DROSOPHILA IN SOLUTION BY 1H NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY 分子名称: ANTENNAPEDIA PROTEIN 著者 Qian, Y.-Q, Billeter, M, Otting, G, Muller, M, Gehring, W.J, Wuthrich, K. 登録日 1991-10-08 公開日 1993-10-31 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 Determination of the three-dimensional structure of the Antennapedia homeodomain from Drosophila in solution by 1H nuclear magnetic resonance spectroscopy. J.Mol.Biol., 214, 1990
1LCA	LACTOBACILLUS CASEI THYMIDYLATE SYNTHASE TERNARY COMPLEX WITH DUMP AND CB3717 分子名称: 10-PROPARGYL-5,8-DIDEAZAFOLIC ACID, 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, THYMIDYLATE SYNTHASE 著者 Birdsall, D.L, Finer-Moore, J, Stroud, R.M. 登録日 1995-06-22 公開日 1995-10-15 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Refined structures of substrate-bound and phosphate-bound thymidylate synthase from Lactobacillus casei. J.Mol.Biol., 232, 1993
2GW6	NMR structure of the human tRNA endonuclease SEN15 subunit 分子名称: tRNA-splicing endonuclease subunit Sen15 著者 Song, J, Markley, J.L, Center for Eukaryotic Structural Genomics (CESG) 登録日 2006-05-03 公開日 2006-05-16 最終更新日 2024-05-29 実験手法 SOLUTION NMR 主引用文献 Three-dimensional structure determined for a subunit of human tRNA splicing endonuclease (Sen15) reveals a novel dimeric fold. J.Mol.Biol., 366, 2007
1G96	HUMAN CYSTATIN C; DIMERIC FORM WITH 3D DOMAIN SWAPPING 分子名称: CHLORIDE ION, CYSTATIN C, GLYCEROL 著者 Janowski, R, Kozak, M, Jankowska, E, Grzonka, Z, Grubb, A, Abrahamson, M, Jaskolski, M. 登録日 2000-11-22 公開日 2001-04-06 最終更新日 2023-08-09 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Human cystatin C, an amyloidogenic protein, dimerizes through three-dimensional domain swapping. Nat.Struct.Biol., 8, 2001
5CHG	Human DNA polymerase lambda L431A mutant- MgdGTP binary and complex with 6 paired DNA 分子名称: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA (5'-D(*CP*AP*GP*TP*AP*C)-3'), DNA (5'-D(P*GP*TP*AP*CP*TP*G)-3'), ... 著者 Liu, M.S, Tsai, M.D. 登録日 2015-07-10 公開日 2016-02-24 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Structural Mechanism for the Fidelity Modulation of DNA Polymerase lambda J.Am.Chem.Soc., 138, 2016
7WB3	Crystal structure of T. maritima Rex in ternary complex 分子名称: DNA (5'-D(*AP*TP*TP*TP*GP*AP*GP*AP*AP*AP*TP*TP*TP*AP*TP*CP*AP*CP*AP*AP*AP*A)-3'), DNA (5'-D(*TP*TP*TP*TP*GP*TP*GP*AP*TP*AP*AP*AP*TP*TP*TP*CP*TP*CP*AP*AP*AP*T)-3'), NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... 著者 Lee, J.Y, Jeong, K.H, Lee, H.J, Park, Y.W. 登録日 2021-12-15 公開日 2022-02-16 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.401 Å) 主引用文献 Structural Basis of Redox-Sensing Transcriptional Repressor Rex with Cofactor NAD + and Operator DNA. Int J Mol Sci, 23, 2022
1D7Q	HUMAN TRANSLATION INITIATION FACTOR EIF1A 分子名称: PROTEIN (N-TERMINAL HISTIDINE TAG), TRANSLATION INITIATION FACTOR 1A 著者 Battiste, J.L, Pestova, T.V, Hellen, C.U.T, Wagner, G. 登録日 1999-10-19 公開日 2000-03-17 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 The eIF1A solution structure reveals a large RNA-binding surface important for scanning function. Mol.Cell, 5, 2000
4RFW	Crystal structure of human retinoid X Receptor alpha-ligand binding domain complex with 9cUAB70 and the coactivator peptide GRIP-1 分子名称: (2E,4E,6Z,8E)-3,7-dimethyl-8-(6,7,8,9-tetrahydro-5H-benzo[7]annulen-5-ylidene)octa-2,4,6-trienoic acid, Nuclear receptor coactivator 2, Retinoic acid receptor RXR-alpha 著者 Xia, G, Muccio, D.D, Smith, C.D. 登録日 2014-09-28 公開日 2015-09-16 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Conformationally Defined Rexinoids and Their Efficacy in the Prevention of Mammary Cancers. J.Med.Chem., 58, 2015
1DRA	CRYSTAL STRUCTURE OF UNLIGANDED ESCHERICHIA COLI DIHYDROFOLATE REDUCTASE. LIGAND-INDUCED CONFORMATIONAL CHANGES AND COOPERATIVITY IN BINDING 分子名称: CALCIUM ION, CHLORIDE ION, DIHYDROFOLATE REDUCTASE, ... 著者 Oatley, S.J, Kraut, J. 登録日 1991-11-06 公開日 1994-01-31 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Crystal structure of unliganded Escherichia coli dihydrofolate reductase. Ligand-induced conformational changes and cooperativity in binding. Biochemistry, 30, 1991
7CNC	cystal structure of human ERH in complex with DGCR8 分子名称: Enhancer of rudimentary homolog, Microprocessor complex subunit DGCR8 著者 Li, F, Shen, S. 登録日 2020-07-30 公開日 2020-10-28 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 ERH facilitates microRNA maturation through the interaction with the N-terminus of DGCR8. Nucleic Acids Res., 48, 2020
4ADI	Crystal structure of the Rubella virus envelope glycoprotein E1 in post-fusion form (crystal form I) 分子名称: 2-acetamido-2-deoxy-beta-D-galactopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, ... 著者 DuBois, R.M, Vaney, M.C, Tortorici, M.A, Al Kurdi, R, Barba-Spaeth, G, Rey, F.A. 登録日 2011-12-26 公開日 2013-01-09 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Functional and Evolutionary Insight from the Crystal Structure of Rubella Virus Protein E1. Nature, 493, 2013

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