8GRO
 
 | | AtOSCA3.1 contracted state | | 分子名称: | CSC1-like protein ERD4 | | 著者 | Zhang, M.F. | | 登録日 | 2022-09-02 | | 公開日 | 2023-06-14 | | 最終更新日 | 2024-07-03 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | A mechanical-coupling mechanism in OSCA/TMEM63 channel mechanosensitivity.
Nat Commun, 14, 2023
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8GQU
 | | AK-42 inhibitor binding human ClC-2 TMD | | 分子名称: | 2-[[2,6-bis(chloranyl)-3-phenylmethoxy-phenyl]amino]pyridine-3-carboxylic acid, Chloride channel protein 2 | | 著者 | Wang, L. | | 登録日 | 2022-08-30 | | 公開日 | 2023-07-05 | | 最終更新日 | 2024-05-08 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Cryo-EM structures of ClC-2 chloride channel reveal the blocking mechanism of its specific inhibitor AK-42.
Nat Commun, 14, 2023
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6PXE
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4XRE
 | | Crystal structure of Gnk2 complexed with mannose | | 分子名称: | Antifungal protein ginkbilobin-2, alpha-D-mannopyranose | | 著者 | Miyakawa, T, Hatano, K, Miyauchi, Y, Suwa, Y, Sawano, Y, Tanokura, M. | | 登録日 | 2015-01-21 | | 公開日 | 2015-02-25 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.597 Å) | | 主引用文献 | A secreted protein with plant-specific cysteine-rich motif functions as a mannose-binding lectin that exhibits antifungal activity.
Plant Physiol., 166, 2014
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4Q6G
 | | Crystal Structure of the C-terminal domain of AcKRS-1 bound with N-acetyl-lysine and ADPNP | | 分子名称: | 1,2-ETHANEDIOL, N(6)-ACETYLLYSINE, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... | | 著者 | Eiler, D.R, Kavran, J, Steitz, T.A. | | 登録日 | 2014-04-22 | | 公開日 | 2014-11-12 | | 最終更新日 | 2023-12-06 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | Polyspecific pyrrolysyl-tRNA synthetases from directed evolution.
Proc.Natl.Acad.Sci.USA, 111, 2014
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4Q05
 | | Crystal structure of an esterase E25 | | 分子名称: | SODIUM ION, esterase E25 | | 著者 | Li, P.Y, Li, C.Y, Zhang, Y.Z. | | 登録日 | 2014-03-31 | | 公開日 | 2014-06-04 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | Structural basis for dimerization and catalysis of a novel esterase from the GTSAG motif subfamily of the bacterial hormone-sensitive lipase family
J.Biol.Chem., 289, 2014
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8GTY
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4YGE
 | | Crystal structure of ERGIC-53/MCFD2, trigonal calcium-bound form 2 | | 分子名称: | CALCIUM ION, CHLORIDE ION, Multiple coagulation factor deficiency protein 2, ... | | 著者 | Satoh, T, Nishio, M, Yagi-Utsumi, M, Suzuki, K, Anzai, T, Mizushima, T, Kamiya, Y, Kato, K. | | 登録日 | 2015-02-26 | | 公開日 | 2016-04-06 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (3.05 Å) | | 主引用文献 | Crystallographic snapshots of the EF-hand protein MCFD2 complexed with the intracellular lectin ERGIC-53 involved in glycoprotein transport.
Acta Crystallogr.,Sect.F, 76, 2020
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4YOP
 | | CRYSTAL STRUCTURE OF HEN EGG-WHITE LYSOZYME | | 分子名称: | CHLORIDE ION, Lysozyme C, SODIUM ION | | 著者 | Sugahara, M, Nakane, T, Suzuki, M, Nango, E. | | 登録日 | 2015-03-12 | | 公開日 | 2015-12-23 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Native sulfur/chlorine SAD phasing for serial femtosecond crystallography
Acta Crystallogr.,Sect.D, 71, 2015
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4YGC
 | | Crystal structure of ERGIC-53/MCFD2, monoclinic calcium-bound form 1 | | 分子名称: | CALCIUM ION, CHLORIDE ION, Multiple coagulation factor deficiency protein 2, ... | | 著者 | Satoh, T, Nishio, M, Yagi-Utsumi, M, Suzuki, K, Anzai, T, Mizushima, T, Kamiya, Y, Kato, K. | | 登録日 | 2015-02-26 | | 公開日 | 2016-04-06 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Crystallographic snapshots of the EF-hand protein MCFD2 complexed with the intracellular lectin ERGIC-53 involved in glycoprotein transport.
Acta Crystallogr.,Sect.F, 76, 2020
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4YGD
 | | Crystal structure of ERGIC-53/MCFD2, monoclinic calcium-bound form 2 | | 分子名称: | CALCIUM ION, CHLORIDE ION, Multiple coagulation factor deficiency protein 2, ... | | 著者 | Satoh, T, Nishio, M, Yagi-Utsumi, M, Suzuki, K, Anzai, T, Mizushima, T, Kamiya, Y, Kato, K. | | 登録日 | 2015-02-26 | | 公開日 | 2016-04-06 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.51 Å) | | 主引用文献 | Crystallographic snapshots of the EF-hand protein MCFD2 complexed with the intracellular lectin ERGIC-53 involved in glycoprotein transport.
Acta Crystallogr.,Sect.F, 76, 2020
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8GHK
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5CGZ
 | | Crystal structure of GalB, the 4-carboxy-2-hydroxymuconate hydratase, from Pseuodomonas putida KT2440 | | 分子名称: | 4-oxalmesaconate hydratase, GLYCEROL, ZINC ION | | 著者 | Mazurkewich, S, Brott, A.S, Kimber, M.S, Seah, S.Y.K. | | 登録日 | 2015-07-09 | | 公開日 | 2016-02-17 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (2.103 Å) | | 主引用文献 | Structural and Kinetic Characterization of the 4-Carboxy-2-hydroxymuconate Hydratase from the Gallate and Protocatechuate 4,5-Cleavage Pathways of Pseudomonas putida KT2440.
J.Biol.Chem., 291, 2016
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3JR8
 | | Crystal Structure of BthTX-II (Asp49-PLA2 from Bothrops jararacussu snake venom) with calcium ions | | 分子名称: | CALCIUM ION, Phospholipase A2 bothropstoxin-2 | | 著者 | Borges, R.J, dos Santos, J.I, Fontes, M.R.M. | | 登録日 | 2009-09-08 | | 公開日 | 2010-09-08 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structural, functional, and bioinformatics studies reveal a new snake venom homologue phospholipase A2 class.
Proteins, 79, 2011
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5CNA
 | | REFINED STRUCTURE OF CONCANAVALIN A COMPLEXED WITH ALPHA-METHYL-D-MANNOPYRANOSIDE AT 2.0 ANGSTROMS RESOLUTION AND COMPARISON WITH THE SACCHARIDE-FREE STRUCTURE | | 分子名称: | CALCIUM ION, CHLORIDE ION, CONCANAVALIN A, ... | | 著者 | Naismith, J.H, Emmerich, C, Habash, J, Harrop, S.J, Helliwell, J.R, Hunter, W.N, Raftery, J, Kalb(Gilboa), A.J, Yariv, J. | | 登録日 | 1994-02-11 | | 公開日 | 1994-05-31 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Refined structure of concanavalin A complexed with methyl alpha-D-mannopyranoside at 2.0 A resolution and comparison with the saccharide-free structure.
Acta Crystallogr.,Sect.D, 50, 1994
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8HMV
 | | Structure of GPR21-Gs complex | | 分子名称: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, ... | | 著者 | Wong, T.S, Gao, W. | | 登録日 | 2022-12-05 | | 公開日 | 2023-03-01 | | 実験手法 | ELECTRON MICROSCOPY (2.91 Å) | | 主引用文献 | Cryo-EM structure of orphan G protein-coupled receptor GPR21.
MedComm (2020), 4, 2023
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6GPL
 | | Crystal structure of human GDP-D-mannose 4,6-dehydratase in complex with GDP-4k6d-Man | | 分子名称: | 1,2-ETHANEDIOL, BICINE, GDP-mannose 4,6 dehydratase, ... | | 著者 | Pfeiffer, M, Krojer, T, Johansson, C, von Delft, F, Bountra, C, Arrowsmith, C.H, Edwards, A, Nidetzky, B, Oppermann, U, Structural Genomics Consortium (SGC) | | 登録日 | 2018-06-06 | | 公開日 | 2018-07-18 | | 最終更新日 | 2024-05-15 | | 実験手法 | X-RAY DIFFRACTION (1.76 Å) | | 主引用文献 | A Parsimonious Mechanism of Sugar Dehydration by Human GDP-Mannose-4,6-dehydratase.
Acs Catalysis, 9, 2019
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6REQ
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4X6R
 | | An Isoform-specific Myristylation Switch Targets RIIb PKA Holoenzymes to Membranes | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, GLYCEROL, MAGNESIUM ION, ... | | 著者 | Zhang, P, Ye, F, Bastidas, A.C, Kornev, A.P, Ginsberg, M.H, Wu, J, Taylor, S.S. | | 登録日 | 2014-12-09 | | 公開日 | 2015-07-22 | | 最終更新日 | 2020-06-24 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | An Isoform-Specific Myristylation Switch Targets Type II PKA Holoenzymes to Membranes.
Structure, 23, 2015
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6GUF
 | | CDK2/CyclinA in complex with CGP74514A | | 分子名称: | Cyclin-A2, Cyclin-dependent kinase 2, N2-[(1R,2S)-2-AMINOCYCLOHEXYL]-N6-(3-CHLOROPHENYL)-9-ETHYL-9H-PURINE-2,6-DIAMINE | | 著者 | Wood, D.J, Korolchuk, S, Tatum, N.J, Wang, L.Z, Endicott, J.A, Noble, M.E.M, Martin, M.P. | | 登録日 | 2018-06-19 | | 公開日 | 2018-12-05 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | | 主引用文献 | Differences in the Conformational Energy Landscape of CDK1 and CDK2 Suggest a Mechanism for Achieving Selective CDK Inhibition.
Cell Chem Biol, 26, 2019
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6R4A
 | | Aurora-A in complex with shape-diverse fragment 55 | | 分子名称: | 2-(benzimidazol-1-yl)-~{N}-(2-phenylethyl)ethanamide, ADENOSINE-5'-DIPHOSPHATE, Aurora kinase A, ... | | 著者 | Bayliss, R, McIntyre, P.J. | | 登録日 | 2019-03-22 | | 公開日 | 2019-05-08 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.937 Å) | | 主引用文献 | Construction of a Shape-Diverse Fragment Set: Design, Synthesis and Screen against Aurora-A Kinase.
Chemistry, 25, 2019
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4R50
 | | Crystal Structure of CNG mimicking NaK-ETPP mutant cocrystallized with Li+ | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, GLYCINE, Potassium channel protein | | 著者 | De March, M, Napolitano, L.M.R, Onesti, S. | | 登録日 | 2014-08-20 | | 公開日 | 2015-07-01 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | | 主引用文献 | A structural, functional, and computational analysis suggests pore flexibility as the base for the poor selectivity of CNG channels.
Proc.Natl.Acad.Sci.USA, 112, 2015
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4WNU
 | | Human Cytochrome P450 2D6 Quinidine Complex | | 分子名称: | Cytochrome P450 2D6, DIMETHYL SULFOXIDE, GLYCEROL, ... | | 著者 | Wang, A, Stout, C.D, Johnson, E.F. | | 登録日 | 2014-10-14 | | 公開日 | 2015-01-14 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.26 Å) | | 主引用文献 | Contributions of Ionic Interactions and Protein Dynamics to Cytochrome P450 2D6 (CYP2D6) Substrate and Inhibitor Binding.
J.Biol.Chem., 290, 2015
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8H9H
 | | Crystal structure of ZBTB7A in complex with GACCC-containing sequence | | 分子名称: | DNA (5'-D(*TP*AP*AP*GP*GP*AP*CP*CP*CP*AP*GP*AP*T)-3'), DNA (5'-D(P*AP*AP*TP*CP*TP*GP*GP*GP*TP*CP*CP*TP*T)-3'), ZINC ION, ... | | 著者 | Yang, Y. | | 登録日 | 2022-10-25 | | 公開日 | 2023-04-26 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | ZBTB7A regulates primed-to-naive transition of pluripotent stem cells via recognition of the PNT-associated sequence by zinc fingers 1-2 and recognition of gamma-globin -200 gene element by zinc fingers 1-4.
Febs J., 290, 2023
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8HAL
 | | Cryo-EM structure of the CBP catalytic core bound to the H4K12acK16ac nucleosome, class 1 | | 分子名称: | CREB-binding protein, DNA (180-mer), Histone H2A type 1-B/E, ... | | 著者 | Kikuchi, M, Morita, S, Wakamori, M, Shin, S, Uchikubo-Kamo, T, Shirouzu, M, Umehara, T. | | 登録日 | 2022-10-26 | | 公開日 | 2023-05-17 | | 最終更新日 | 2023-07-26 | | 実験手法 | ELECTRON MICROSCOPY (4.4 Å) | | 主引用文献 | Epigenetic mechanisms to propagate histone acetylation by p300/CBP.
Nat Commun, 14, 2023
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