PDB: 230764 件ウェブページステータス検索Chemie searchBIRD

---

3R98	Joint Neutron and X-ray structure of Cytochrome c peroxidase 分子名称: Cytochrome c peroxidase, PROTOPORPHYRIN IX CONTAINING FE 著者 Blakeley, M.P, Fisher, S.J, Gumiero, A, Moody, P.C.E, Raven, E.L. 登録日 2011-03-25 公開日 2012-04-04 最終更新日 2024-03-20 実験手法 NEUTRON DIFFRACTION (2.4 Å), X-RAY DIFFRACTION 主引用文献 Hydrogen bonds in heme peroxidases: a combined X-ray and neutron study of cytochrome c peroxidase To be Published
3PYG	Mycobacterium tuberculosis 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase (IspE) in complex with ADP 分子名称: 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, ADENOSINE-5'-DIPHOSPHATE 著者 Shan, S, Chen, X.H, Liu, T, Zhao, H.C, Rao, Z.H, Lou, Z.Y. 登録日 2010-12-13 公開日 2012-01-25 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (1.99 Å) 主引用文献 The Structural Basis for anti-TB Drug Discovery targeting of 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase (IspE) from Mycobacterium tuberculosis To be Published
6KXH	Alp1U_Y247F mutant in complex with Fluostatin C 分子名称: D-MALATE, Fluostatin C, Putative hydrolase, ... 著者 Zhang, L, Yingli, Z, De, B.C, Zhang, C. 登録日 2019-09-11 公開日 2020-09-16 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (1.78039551 Å) 主引用文献 Mutation of an atypical oxirane oxyanion hole improves regioselectivity of the alpha / beta-fold epoxide hydrolase Alp1U. J.Biol.Chem., 295, 2020
3QGE	Crystal structure of the hepatitis C virus NS5B RNA-dependent RNA polymerase complex with (2E)-3-(4-{[(1-{[(13-cyclohexyl-6-oxo-6,7-dihydro-5H-indolo[1,2-d][1,4]benzodiazepin-10-yl)carbonyl]amino}cyclopentyl)carbonyl]amino}phenyl)prop-2-enoic acid and (2R)-4-(2,6-dimethoxypyrimidin-4-yl)-N-(4-methoxybenzyl)-1-{[4-(trifluoromethoxy)phenyl]sulfonyl}piperazine-2-carboxamide 分子名称: (2E)-3-(4-{[(1-{[(13-cyclohexyl-6-oxo-6,7-dihydro-5H-indolo[1,2-d][1,4]benzodiazepin-10-yl)carbonyl]amino}cyclopentyl)carbonyl]amino}phenyl)prop-2-enoic acid, (2R)-4-(2,6-dimethoxypyrimidin-4-yl)-N-(4-methoxybenzyl)-1-{[4-(trifluoromethoxy)phenyl]sulfonyl}piperazine-2-carboxamide, RNA-directed RNA polymerase, ... 著者 Sheriff, S. 登録日 2011-01-24 公開日 2011-04-20 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Investigation of the mode of binding of a novel series of N-benzyl-4-heteroaryl-1-(phenylsulfonyl)piperazine-2-carboxamides to the hepatitis C virus polymerase. Bioorg.Med.Chem.Lett., 21, 2011
1F04	SOLUTION STRUCTURE OF OXIDIZED BOVINE MICROSOMAL CYTOCHROME B5 MUTANT (E44A, E48A, E56A, D60A) AND ITS INTERACTION WITH CYTOCHROME C 分子名称: CYTOCHROME B5, PROTOPORPHYRIN IX CONTAINING FE 著者 Wu, Y.B, Lu, J, Qian, C.M, Tang, W.X, Li, E.C, Wang, J.F, Wang, Y.H, Wang, W.H, Lu, J.X, Xie, Y, Huang, Z.X. 登録日 2000-05-14 公開日 2000-06-21 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 Solution structure of cytochrome b(5) mutant (E44/48/56A/D60A) and its interaction with cytochrome c. Eur.J.Biochem., 268, 2001
2LMG	Solution Structure of The C-terminal Domain (537-610) of Human Heat Shock Protein 70 分子名称: Heat shock 70 kDa protein 1A/1B 著者 Zhou, C, Gao, X, Wu, M, Hu, H. 登録日 2011-12-01 公開日 2012-01-11 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 The C-terminal helices of heat shock protein 70 are essential for J-domain binding and ATPase activation. J.Biol.Chem., 287, 2012
2ORB	The structure of the anti-c-myc antibody 9E10 Fab fragment 分子名称: Monoclonal anti-c-myc antibody 9E10, SULFATE ION 著者 Krauss, N, Scheerer, P, Hoehne, W. 登録日 2007-02-02 公開日 2008-02-12 最終更新日 2024-11-13 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 The structure of the anti-c-myc antibody 9E10 Fab fragment/epitope peptide complex reveals a novel binding mode dominated by the heavy chain hypervariable loops. Proteins, 73, 2008
2DQ5	solution structure of the Mid1 B Box2 Chc(D/C)C2H2 Zinc-Binding Domain: insights into an evolutionary conserved ring fold 分子名称: Midline-1, ZINC ION 著者 Massiah, M.A, Matts, J.A.B, Short, K.M, Simmons, B.N, Singireddy, S, Zou, J, Cox, T.C. 登録日 2006-05-20 公開日 2007-04-03 最終更新日 2024-05-29 実験手法 SOLUTION NMR 主引用文献 Solution Structure of the MID1 B-box2 CHC(D/C)C(2)H(2) Zinc-binding Domain: Insights into an Evolutionarily Conserved RING Fold J.Mol.Biol., 369, 2007
4I32	Crystal structure of HCV NS3/4A D168V protease complexed with compound 4 分子名称: (2R,6S,7E,10E,13aR,14aR,16aS)-2-{[7-methoxy-8-methyl-2-(propan-2-yloxy)quinolin-4-yl]oxy}-N-[(1-methylcyclopropyl)sulfonyl]-6-{[(1-methyl-1H-pyrazol-3-yl)carbonyl]amino}-5,16-dioxo-1,2,3,6,9,12,13,13a,14,15,16,16a-dodecahydrocyclopropa[e]pyrrolo[1,2-a][1,4]diazacyclopentadecine-14a(5H)-carboxamide, Genome polyprotein, HCV non-structural protein 4A, ... 著者 Lemke, C.T. 登録日 2012-11-23 公開日 2013-01-02 最終更新日 2024-11-06 実験手法 X-RAY DIFFRACTION (2.3001 Å) 主引用文献 Molecular Mechanism by Which a Potent Hepatitis C Virus NS3-NS4A Protease Inhibitor Overcomes Emergence of Resistance. J.Biol.Chem., 288, 2013
3U27	Crystal structure of ethanolamine utilization protein EutL from Leptotrichia buccalis C-1013-b 分子名称: CALCIUM ION, GLYCEROL, Microcompartments protein, ... 著者 Wu, R, Gu, M, Kerfeld, C.A, Salmeen, A, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) 登録日 2011-10-01 公開日 2012-02-08 最終更新日 2024-11-06 実験手法 X-RAY DIFFRACTION (1.852 Å) 主引用文献 Crystal structure of ethanolamine utilization protein EutL from Leptotrichia buccalis C-1013-b To be Published
4I31	Crystal structure of HCV NS3/NS4A protease complexed with compound 4 分子名称: (2R,6S,7E,10E,13aR,14aR,16aS)-2-{[7-methoxy-8-methyl-2-(propan-2-yloxy)quinolin-4-yl]oxy}-N-[(1-methylcyclopropyl)sulfonyl]-6-{[(1-methyl-1H-pyrazol-3-yl)carbonyl]amino}-5,16-dioxo-1,2,3,6,9,12,13,13a,14,15,16,16a-dodecahydrocyclopropa[e]pyrrolo[1,2-a][1,4]diazacyclopentadecine-14a(5H)-carboxamide, Genome polyprotein, HCV non-structural protein 4A, ... 著者 Lemke, C.T. 登録日 2012-11-23 公開日 2013-01-02 最終更新日 2024-11-27 実験手法 X-RAY DIFFRACTION (1.9301 Å) 主引用文献 Molecular Mechanism by Which a Potent Hepatitis C Virus NS3-NS4A Protease Inhibitor Overcomes Emergence of Resistance. J.Biol.Chem., 288, 2013
1R1W	CRYSTAL STRUCTURE OF THE TYROSINE KINASE DOMAIN OF THE HEPATOCYTE GROWTH FACTOR RECEPTOR C-MET 分子名称: HEPATOCYTE GROWTH FACTOR RECEPTOR 著者 Schiering, N, Knapp, S, Marconi, M, Flocco, M.M, Cui, J, Perego, R, Rusconi, L, Cristiani, C. 登録日 2003-09-25 公開日 2003-10-07 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Crystal structure of the tyrosine kinase domain of the hepatocyte growth factor receptor c-Met and its complex with the microbial alkaloid K-252a Proc.Natl.Acad.Sci.USA, 100, 2003
2IUN	Structure of the C-terminal head domain of the avian adenovirus CELO long fibre (P21 crystal form) 分子名称: AVIAN ADENOVIRUS CELO LONG FIBRE, CALCIUM ION 著者 Guardado-Calvo, P, Llamas-Saiz, A.L, Fox, G.C, van Raaij, M.J. 登録日 2006-06-06 公開日 2007-06-19 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Structure of the C-terminal head domain of the fowl adenovirus type 1 long fiber. J. Gen. Virol., 88, 2007
2XWY	Structure of MK-3281, a Potent Non-Nucleoside Finger-Loop Inhibitor, in complex with the Hepatitis C Virus NS5B Polymerase 分子名称: (7R)-14-cyclohexyl-7-{[2-(dimethylamino)ethyl](methyl)amino}-7,8-dihydro-6H-indolo[1,2-e][1,5]benzoxazocine-11-carboxylic acid, MANGANESE (II) ION, RNA-DIRECTED RNA POLYMERASE 著者 Di Marco, S, Baiocco, P. 登録日 2010-11-06 公開日 2010-12-22 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.53 Å) 主引用文献 Discovery of (7R)-14-Cyclohexyl-7-{[2-(Dimethylamino)Ethyl] (Methyl)Amino}-7,8-Dihydro-6H-Indolo[1,2-E][1,5] Benzoxazocine -11-Carboxylic Acid (Mk-3281), a Potent and Orally Bioavailable Finger-Loop Inhibitor of the Hepatitis C Virus Ns5B Polymerase J.Med.Chem., 54, 2011
3PVB	Crystal structure of (73-244)RIa:C holoenzyme of cAMP-dependent Protein kinase 分子名称: GLYCEROL, MANGANESE (II) ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... 著者 Boettcher, A.J, Wu, J, Kim, C, Yang, J, Bruystens, J, Cheung, N, Pennypacker, J.K, Blumenthal, D.A, Kornev, A.P, Taylor, S.S. 登録日 2010-12-06 公開日 2011-02-02 最終更新日 2024-11-20 実験手法 X-RAY DIFFRACTION (3.3 Å) 主引用文献 Crystal structure of (73-244)RIa:C holoenzyme of cAMP-dependent Protein kinase Structure, 19, 2011
2XI2	HCV-H77 NS5B Apo Polymerase 分子名称: RNA-directed RNA polymerase, SULFATE ION 著者 Harrus, D, Ahmed-El-Sayed, N, Simister, P.C, Miller, S, Triconnet, M, Hagedorn, C.H, Mahias, K, Rey, F.A, Astier-Gin, T, Bressanelli, S. 登録日 2010-06-25 公開日 2010-08-04 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Further Insights Into the Roles of GTP and the C- Terminus of the Hepatitis C Virus Polymerase in the Initiation of RNA Synthesis J.Biol.Chem., 285, 2010
4DCK	Crystal structure of the C-terminus of voltage-gated sodium channel in complex with FGF13 and CaM 分子名称: Calmodulin, Fibroblast growth factor 13, MAGNESIUM ION, ... 著者 Chung, B.C, Wang, C, Yan, H, Pitt, G.S, Lee, S.Y. 登録日 2012-01-17 公開日 2012-06-27 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Crystal Structure of the Ternary Complex of a NaV C-Terminal Domain, a Fibroblast Growth Factor Homologous Factor, and Calmodulin. Structure, 20, 2012
3QR1	Crystal Structure of L. pealei PLC21 分子名称: CALCIUM ION, PHOSPHOLIPASE C-BETA (PLC-BETA) 著者 Lyon, A.M, Suddala, K.C, Northup, J.K, Tesmer, J.J.G. 登録日 2011-02-16 公開日 2011-08-10 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 An autoinhibitory helix in the C-terminal region of phospholipase C-beta mediates Galphaq activation. Nat.Struct.Mol.Biol., 18, 2011
1SBM	Crystal Structure of Reduced Mesopone cytochrome c peroxidase (R-isomer) 分子名称: Cytochrome c peroxidase, mitochondrial, FE-(4-MESOPORPHYRINONE)-R-ISOMER 著者 Bhaskar, B, Immoos, C.E, Sulc, F, Cohen, M.S, Farmer, P.J, Poulos, T.L. 登録日 2004-02-10 公開日 2005-06-14 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (1.69 Å) 主引用文献 Crystal Structures of Resting (Fe3+), Reduced (Fe2+) and Reduced-NO adduct of Mesopone cytochrome c peroxidase (MpCcP) - R-isomer To be Published
1S4D	Crystal Structure Analysis of the S-adenosyl-L-methionine dependent uroporphyrinogen-III C-methyltransferase SUMT 分子名称: GLYCEROL, S-ADENOSYL-L-HOMOCYSTEINE, Uroporphyrin-III C-methyltransferase 著者 Vevodova, J, Graham, R.M, Raux, E, Schubert, H.L, Roper, D.I, Brindley, A.A, Scott, A.I, Roessner, C.A, Stamford, N.P.J, Stroupe, M.E, Getzoff, E.D, Warren, M.J, Wilson, K.S. 登録日 2004-01-16 公開日 2004-11-30 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Structure/Function Studies on a S-Adenosyl-l-methionine-dependent Uroporphyrinogen III C Methyltransferase (SUMT), a Key Regulatory Enzyme of Tetrapyrrole Biosynthesis J.Mol.Biol., 344, 2004
2ZFZ	Crystal structure of the C-terminal domain hexamer of ArgR from Mycobacterium tuberculosis in complex with arginine 分子名称: ARGININE, Arginine repressor, GUANIDINE 著者 Cherney, L.T, Cherney, M.M, Garen, C.R, Lu, G.J, James, M.N.G, TB Structural Genomics Consortium (TBSGC) 登録日 2008-01-16 公開日 2008-02-12 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Structure of the C-terminal domain of the arginine repressor protein from Mycobacterium tuberculosis. Acta Crystallogr.,Sect.D, 64, 2008
2IDE	Crystal Structure of the molybdenum cofactor biosynthesis protein C (TTHA1789) from Thermus Theromophilus HB8 分子名称: Molybdenum cofactor biosynthesis protein C, PHOSPHATE ION 著者 Jeyakanthan, J, Kanaujia, S.P, Vasuki Ranjani, C, Sekar, K, Baba, S, Ebihara, A, Kuramitsu, S, Shinkai, A, Shiro, Y, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2006-09-15 公開日 2007-09-25 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Crystal Structure of the molybdenum cofactor biosynthesis protein C (TTHA1789) from Thermus Theromophilus HB8 To be Published
1SDQ	Structure of reduced-NO adduct of mesopone cytochrome c peroxidase 分子名称: Cytochrome c peroxidase, mitochondrial, FE-(4-MESOPORPHYRINONE)-R-ISOMER, ... 著者 Bhaskar, B, Immoos, C.E, Sulc, F, Cohem, M.S, Farmer, P.J, Poulos, T.L. 登録日 2004-02-13 公開日 2005-07-12 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (1.69 Å) 主引用文献 Crystal structures of resting (Fe3+), reduced (Fe2+) and NO-bound states of mesopone cytochrome c peroxidase (MpCcP) (R-isomer) To be Published
1OHM	Sakacin P variant that is structurally stabilized by an inserted C-terminal disulfide bridge. 分子名称: BACTERIOCIN SAKACIN P 著者 Uteng, M, Hauge, H.H, Markwick, P.R, Fimland, G, Mantzilas, D, Nissen-Meyer, J, Muhle-Goll, C. 登録日 2003-05-28 公開日 2003-09-22 最終更新日 2024-10-23 実験手法 SOLUTION NMR 主引用文献 Three-Dimensional Structure in Lipid Micelles of the Pediocin-Like Antimicrobial Peptide Sakacin P and a Sakacin P Variant that is Structurally Stabilized by an Inserted C-Terminal Disulfide Bridge Biochemistry, 42, 2003
4JKT	Crystal structure of mouse Glutaminase C, BPTES-bound form 分子名称: Glutaminase kidney isoform, mitochondrial, N,N'-[sulfanediylbis(ethane-2,1-diyl-1,3,4-thiadiazole-5,2-diyl)]bis(2-phenylacetamide) 著者 Fornezari, C, Ferreira, A.P.S, Dias, S.M.G, Ambrosio, A.L.B. 登録日 2013-03-11 公開日 2013-08-14 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.77 Å) 主引用文献 Active Glutaminase C Self-assembles into a Supratetrameric Oligomer That Can Be Disrupted by an Allosteric Inhibitor. J.Biol.Chem., 288, 2013

<28293031323334353637383940414243>