PDB: 97138 件ウェブページステータス検索Chemie searchBIRD

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4HCW	Structure of a eukaryotic thiaminase-I 分子名称: thiaminase-I 著者 Kreinbring, C.A, Hubbard, P.A, Petsko, G.A, Ringe, D. 登録日 2012-10-01 公開日 2013-10-02 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.705 Å) 主引用文献 Structure of a eukaryotic thiaminase I. Proc.Natl.Acad.Sci.USA, 111, 2014
2CSC	Structure of ternary complexes of CITRATE SYNTHASE WITH D-AND L-MALATE: mechanistic implications 分子名称: CARBOXYMETHYL COENZYME *A, CITRATE SYNTHASE, D-MALATE 著者 Karpusas, M, Holland, D, Remington, S.J. 登録日 1990-05-07 公開日 1991-04-15 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 1.9-A structures of ternary complexes of citrate synthase with D- and L-malate: mechanistic implications. Biochemistry, 30, 1991
2K8M	S100A13-C2A binary complex structure 分子名称: Protein S100-A13, Putative uncharacterized protein 著者 Mohan, S.K, Rani, S.G, Kumar, S.M, Yu, C. 登録日 2008-09-14 公開日 2009-03-17 最終更新日 2024-05-01 実験手法 SOLUTION NMR 主引用文献 S100A13-C2A binary complex structure-a key component in the acidic fibroblast growth factor for the non-classical pathway. Biochem.Biophys.Res.Commun., 380, 2009
4JTD	Crystal structure of Kv1.2-2.1 paddle chimera channel in complex with Lys27Met mutant of Charybdotoxin 分子名称: (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, POTASSIUM ION, ... 著者 Banerjee, A, Lee, A, Campbell, E, MacKinnon, R. 登録日 2013-03-23 公開日 2013-06-12 最終更新日 2019-12-25 実験手法 X-RAY DIFFRACTION (2.54 Å) 主引用文献 Structure of a pore-blocking toxin in complex with a eukaryotic voltage-dependent K(+) channel. Elife, 2, 2013
5HNE	X-RAY CRYSTAL STRUCTURE OF HUMAN MITOCHONDRIAL BRANCHED CHAIN AMINOTRANSFERASE (BCATM) COMPLEXED WITH A 2-ARYL BENZIMIDAZOLE COMPOUND AND AN INTERNAL ALDIMINE LINKED PLP COFACTOR 分子名称: 1,2-ETHANEDIOL, 1-[(1R,3S)-3-{[(5-bromothiophen-2-yl)carbonyl]amino}cyclohexyl]-N-methyl-2-(pyridin-2-yl)-1H-benzimidazole-5-carboxamide, Branched-chain-amino-acid aminotransferase, ... 著者 Somers, D.O. 登録日 2016-01-18 公開日 2016-05-04 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (2.04 Å) 主引用文献 Discovery and Optimization of Potent, Selective, and in Vivo Efficacious 2-Aryl Benzimidazole BCATm Inhibitors. Acs Med.Chem.Lett., 7, 2016
6U85	Site-specific lysine arylation as an alternative bioconjugation strategy for chemically programmed antibodies and antibody-drug conjugates 分子名称: Antibody Fab heavy chain, GLYCEROL, antibody Fab Light chain 著者 Park, H, Rader, C. 登録日 2019-09-04 公開日 2019-11-13 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.78 Å) 主引用文献 Site-Specific Lysine Arylation as an Alternative Bioconjugation Strategy for Chemically Programmed Antibodies and Antibody-Drug Conjugates. Bioconjug.Chem., 30, 2019
5OW3	Crystal structure of a C-terminally truncated trimeric ectodomain of the Arabidopsis thaliana gamete fusion protein HAP2 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, GLYCEROL, ... 著者 Fedry, J, Legrand, P, Rey, F.A, Krey, T. 登録日 2017-08-30 公開日 2018-08-22 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.75 Å) 主引用文献 Evolutionary diversification of the HAP2 membrane insertion motifs to drive gamete fusion across eukaryotes. PLoS Biol., 16, 2018
7CYL	Crystal structure of Karyopherin-beta2 in complex with FUS PY-NLS(P525L) 分子名称: RNA-binding protein FUS, Transportin-1 著者 Yoshizawa, T, Chook, Y.M. 登録日 2020-09-03 公開日 2021-02-24 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Mechanism of karyopherin-beta 2 binding and nuclear import of ALS variants FUS(P525L) and FUS(R495X). Sci Rep, 11, 2021
5OW4	Crystal structure of a protease-resistant fragment of the Trypanosoma cruzi gamete fusion protein HAP2 ectodomain 分子名称: Uncharacterized protein 著者 Fedry, J, Rey, F.A, Krey, T. 登録日 2017-08-30 公開日 2018-08-22 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Evolutionary diversification of the HAP2 membrane insertion motifs to drive gamete fusion across eukaryotes. PLoS Biol., 16, 2018
7P0R	Crystal structure of L-Trp/Indoleamine 2,3-dioxygenase (hIDO1) complex with the JK-loop refined in the intermediate conformation 分子名称: GLYCEROL, Indoleamine 2,3-dioxygenase 1, N'-Formylkynurenine, ... 著者 Mirgaux, M, Wouters, J. 登録日 2021-06-30 公開日 2021-12-29 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Temporary Intermediates of L-Trp Along the Reaction Pathway of Human Indoleamine 2,3-Dioxygenase 1 and Identification of an Exo Site. Int J Tryptophan Res, 14, 2021
7P0N	Crystal structure of L-Trp/Indoleamine 2,3-dioxygenagse 1 (hIDO1) complex with the JK-loop refined in the open conformation 分子名称: CHLORIDE ION, GLYCEROL, Indoleamine 2,3-dioxygenase 1, ... 著者 Mirgaux, M, Wouters, J. 登録日 2021-06-30 公開日 2021-12-29 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Temporary Intermediates of L-Trp Along the Reaction Pathway of Human Indoleamine 2,3-Dioxygenase 1 and Identification of an Exo Site. Int J Tryptophan Res, 14, 2021
7PC6	DNA-binding domain of a p53 homolog from the hydrothermal vent annelid Alvinella pompejana 分子名称: 1,2-ETHANEDIOL, DNA-binding domain, ZINC ION 著者 Balourdas, D.-I, Knapp, S, Soussi, T, Joerger, A.C, Structural Genomics Consortium (SGC) 登録日 2021-08-03 公開日 2022-03-23 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.92 Å) 主引用文献 Evolutionary history of the p53 family DNA-binding domain: insights from an Alvinella pompejana homolog. Cell Death Dis, 13, 2022
6XB7	IRES-targeting Small Molecule Inhibits Enterovirus 71 Replication via Allosteric Stabilization of a Ternary Complex 分子名称: 3-amino-N-(diaminomethylidene)-5-(dimethylamino)-6-(phenylethynyl)pyrazine-2-carboxamide, RNA (41-MER) 著者 Tolbert, B.S, Davila, J, Sugarman, A.L, Chiu, L.Y. 登録日 2020-06-05 公開日 2020-09-02 最終更新日 2024-05-01 実験手法 SOLUTION NMR 主引用文献 IRES-targeting small molecule inhibits enterovirus 71 replication via allosteric stabilization of a ternary complex. Nat Commun, 11, 2020
4JTC	Crystal structure of Kv1.2-2.1 paddle chimera channel in complex with Charybdotoxin in Cs+ 分子名称: (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, CESIUM ION, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... 著者 Banerjee, A, Lee, A, Campbell, E, MacKinnon, R. 登録日 2013-03-23 公開日 2013-06-12 最終更新日 2019-12-25 実験手法 X-RAY DIFFRACTION (2.56 Å) 主引用文献 Structure of a pore-blocking toxin in complex with a eukaryotic voltage-dependent K(+) channel. Elife, 2, 2013
6W35	A new Autotaxin Inhibitor for the Treatment of Idiopathic Pulmonary Fibrosis: A Clinical Candidate Discovered Using DNA-Encoded Chemistry 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-fluoranyl-~{N}-[(2~{R})-1-[1-(2~{H}-indazol-5-yl)-3-methyl-2,4-bis(oxidanylidene)-1,3,8-triazaspiro[4.5]decan-8-yl]-3-methyl-1-oxidanylidene-butan-2-yl]-5-(trifluoromethyl)benzamide, CALCIUM ION, ... 著者 Cuozzo, J.W. 登録日 2020-03-09 公開日 2020-07-08 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.98 Å) 主引用文献 Novel Autotaxin Inhibitor for the Treatment of Idiopathic Pulmonary Fibrosis: A Clinical Candidate Discovered Using DNA-Encoded Chemistry. J.Med.Chem., 63, 2020
7N7S	Crystal Structure of Hydroxymethylglutaryl-CoA reductase from Elizabethkingia anophelis NUHP1 分子名称: 1,2-ETHANEDIOL, CITRIC ACID, Hydroxymethylglutaryl-CoA reductase, ... 著者 Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2021-06-11 公開日 2021-06-23 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Crystal Structure of Hydroxymethylglutaryl-CoA reductase from Elizabethkingia anophelis NUHP1 To be published
4HDQ	Crystal Structure of the Ternary Complex of KRIT1 bound to both the Rap1 GTPase and the Heart of Glass (HEG1) cytoplasmic tail 分子名称: GLYCEROL, Krev interaction trapped protein 1, MAGNESIUM ION, ... 著者 Gingras, A.R. 登録日 2012-10-02 公開日 2013-07-10 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 The Structure of the Ternary Complex of Krev Interaction Trapped 1 (KRIT1) Bound to Both the Rap1 GTPase and the Heart of Glass (HEG1) Cytoplasmic Tail. J.Biol.Chem., 288, 2013
5OMF	Closed, ternary structure of KOD DNA polymerase 分子名称: 1,2-ETHANEDIOL, 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, DNA (5'-D(*GP*AP*CP*CP*AP*CP*GP*GP*CP*CP*AP*C)-3'), ... 著者 Kropp, H.M, Betz, K, Wirth, J, Diederichs, K, Marx, A. 登録日 2017-07-31 公開日 2017-12-20 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.092 Å) 主引用文献 Crystal structures of ternary complexes of archaeal B-family DNA polymerases. PLoS ONE, 12, 2017
6UWR	Clostridium difficile binary toxin translocase CDTb in asymmetric tetradecamer conformation 分子名称: ADP-ribosyltransferase binding component, CALCIUM ION 著者 Xu, X, Pozharski, E, des Georges, A. 登録日 2019-11-05 公開日 2020-01-22 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (2.8 Å) 主引用文献 Structure of the cell-binding component of theClostridium difficilebinary toxin reveals a di-heptamer macromolecular assembly. Proc.Natl.Acad.Sci.USA, 117, 2020
4CRM	Cryo-EM of a pre-recycling complex with eRF1 and ABCE1 分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, EUKARYOTIC PEPTIDE CHAIN RELEASE FACTOR SUBUNIT 1, ... 著者 Preis, A, Heuer, A, Barrio-Garcia, C, Hauser, A, Eyler, D, Berninghausen, O, Green, R, Becker, T, Beckmann, R. 登録日 2014-02-28 公開日 2014-07-23 最終更新日 2024-05-08 実験手法 ELECTRON MICROSCOPY (8.75 Å) 主引用文献 Cryoelectron Microscopic Structures of Eukaryotic Translation Termination Complexes Containing Erf1-Erf3 or Erf1-Abce1. Cell Rep., 8, 2014
5X8Q	Crystal Structure of the mutant Human ROR gamma Ligand Binding Domain With rockogenin. 分子名称: (1R,2S,4S,5'R,6R,7S,8R,9S,10R,12S,13S,16S,18S)-5',7,9,13-tetramethylspiro[5-oxapentacyclo[10.8.0.0^{2,9}.0^{4,8}.0^{13,18}]icosane-6,2'-oxane]-10,16-diol, Nuclear receptor ROR-gamma, Nuclear receptor corepressor 2 著者 Noguchi, M, Nomura, A, Murase, K, Doi, S, Yamaguchi, K, Adachi, T. 登録日 2017-03-03 公開日 2017-06-07 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Ternary complex of human ROR gamma ligand-binding domain, inverse agonist and SMRT peptide shows a unique mechanism of corepressor recruitment Genes Cells, 22, 2017
4V0U	The crystal structure of ternary PP1G-PPP1R15B and G-actin complex 分子名称: ACTIN, ALPHA SKELETAL MUSCLE, ADENOSINE-5'-TRIPHOSPHATE, ... 著者 Chen, R, Yan, Y, Casado, A.C, Ron, D, Read, R.J. 登録日 2014-09-18 公開日 2015-03-25 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (7.88 Å) 主引用文献 G-actin provides substrate-specificity to eukaryotic initiation factor 2 alpha holophosphatases. Elife, 4, 2015
2KPC	Structure determination of the top-loop of the conserved 3 terminal secondary structure in the genome of YFV 分子名称: RNA (5'-R(*UP*GP*AP*GP*CP*AP*CP*AP*GP*UP*UP*UP*GP*CP*UP*CP*A)-3') 著者 Lescrinier, E, Dyubankova, N, Nauwelaerts, K, Jones, R, Herdewijn, P. 登録日 2009-10-12 公開日 2010-06-30 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 Structure Determination of the Top-Loop of the Conserved 3'-Terminal Secondary Structure in the Genome of Flaviviruses. Chembiochem, 11, 2010
2KPD	Structure determination of the top-loop of the conserved 3 terminal secondary structure in the genome of YFV-mutant 分子名称: RNA (5'-R(*UP*GP*AP*GP*CP*UP*CP*AP*GP*UP*UP*UP*GP*CP*UP*CP*A)-3') 著者 Lescrinier, E, Dyubankova, N, Nauwelaerts, K, Jones, R, Herdewijn, P. 登録日 2009-10-12 公開日 2010-06-30 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 Structure Determination of the Top-Loop of the Conserved 3'-Terminal Secondary Structure in the Genome of Flaviviruses. Chembiochem, 11, 2010
5C4E	Crystal structure of GTB + UDP-Glc + H-antigen acceptor 分子名称: 2-(2-METHOXYETHOXY)ETHANOL, Histo-blood group ABO system transferase, MANGANESE (II) ION, ... 著者 Gagnon, S, Meloncelli, P, Zheng, R.B, Haji-Ghassemi, O, Johal, A.R, Borisova, S, Lowary, T.L, Evans, S.V. 登録日 2015-06-18 公開日 2015-09-23 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 High Resolution Structures of the Human ABO(H) Blood Group Enzymes in Complex with Donor Analogs Reveal That the Enzymes Utilize Multiple Donor Conformations to Bind Substrates in a Stepwise Manner. J.Biol.Chem., 290, 2015

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