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7SYW
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Structure of the wt IRES eIF5B-containing 48S initiation complex, closed conformation. Structure 15(wt)
分子名称: 18S rRNA, 40S ribosomal protein S2, 40S ribosomal protein S21, ...
著者Brown, Z.P, Abaeva, I.S, De, S, Hellen, C.U.T, Pestova, T.V, Frank, J.
登録日2021-11-25
公開日2022-07-13
最終更新日2023-02-01
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Molecular architecture of 40S translation initiation complexes on the hepatitis C virus IRES.
Embo J., 41, 2022
7SYO
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Structure of the HCV IRES bound to the 40S ribosomal subunit, head open. Structure 9(delta dII)
分子名称: 18S rRNA, 40S ribosomal protein S2, HCV IRES, ...
著者Brown, Z.P, Abaeva, I.S, De, S, Hellen, C.U.T, Pestova, T.V, Frank, J.
登録日2021-11-25
公開日2022-07-27
最終更新日2022-08-24
実験手法ELECTRON MICROSCOPY (4.6 Å)
主引用文献Molecular architecture of 40S translation initiation complexes on the hepatitis C virus IRES.
Embo J., 41, 2022
7VBA
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BU of 7vba by Molmil
Structure of the pre state human RNA Polymerase I Elongation Complex
分子名称: 5'-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]methyl}phosphoryl]cytidine, DNA (5'-D(P*A*CP*TP*GP*TP*CP*CP*TP*CP*TP*GP*GP*C)-3'), DNA (5'-D(P*GP*CP*CP*AP*GP*AP*GP*AP*CP*AP*GP*CP*GP*AP*GP*TP*CP*AP*GP*CP*AP*A)-3'), ...
著者Zhao, D, Liu, W, Chen, K, Yang, H, Xu, Y.
登録日2021-08-31
公開日2022-02-16
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (2.89 Å)
主引用文献Structure of the human RNA polymerase I elongation complex.
Cell Discov, 7, 2021
5IFM
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BU of 5ifm by Molmil
Human NONO (p54nrb) Homodimer
分子名称: CHLORIDE ION, GLYCEROL, Non-POU domain-containing octamer-binding protein, ...
著者Knott, G.J, Bond, C.S.
登録日2016-02-26
公開日2016-11-09
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献A crystallographic study of human NONO (p54(nrb)): overcoming pathological problems with purification, data collection and noncrystallographic symmetry.
Acta Crystallogr D Struct Biol, 72, 2016
7VBC
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Back track state of human RNA Polymerase I Elongation Complex
分子名称: DNA (5'-D(*GP*TP*AP*CP*TP*GP*TP*CP*CP*TP*CP*TP*GP*G)-3'), DNA (5'-D(P*AP*GP*GP*AP*CP*AP*GP*CP*GP*TP*GP*TP*CP*AP*GP*CP*AP*AP*TP*A)-3'), DNA-directed RNA polymerase I subunit RPA1, ...
著者Zhao, D, Liu, W, Chen, K, Yang, H, Xu, Y.
登録日2021-08-31
公開日2022-02-16
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (3.01 Å)
主引用文献Structure of the human RNA polymerase I elongation complex.
Cell Discov, 7, 2021
4F6N
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Crystal structure of Kaiso zinc finger DNA binding protein in complex with methylated CpG site DNA
分子名称: DNA (5'-D(*CP*GP*TP*AP*TP*AP*GP*AP*(5CM)P*GP*(5CM)P*GP*GP*TP*GP*AP*CP*AP*C)-3'), DNA (5'-D(*GP*TP*GP*TP*CP*AP*CP*(5CM)P*GP*(5CM)P*GP*TP*CP*TP*AP*TP*AP*CP*G)-3'), GLYCEROL, ...
著者Buck-Koehntop, B.A, Stanfield, R.L, Ekiert, D.C, Martinez-Yamout, M.A, Dyson, H.J, Wilson, I.A, Wright, P.E.
登録日2012-05-15
公開日2012-09-05
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Molecular basis for recognition of methylated and specific DNA sequences by the zinc finger protein Kaiso.
Proc.Natl.Acad.Sci.USA, 109, 2012
7VBB
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Structure of the post state human RNA Polymerase I Elongation Complex
分子名称: DNA (25-MER), DNA (5'-D(*CP*TP*GP*TP*CP*CP*TP*CP*TP*GP*GP*CP*GP*A)-3'), DNA-directed RNA polymerase I subunit RPA1, ...
著者Zhao, D, Liu, W, Chen, K, Yang, H, Xu, Y.
登録日2021-08-31
公開日2022-03-02
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (2.81 Å)
主引用文献Structure of the human RNA polymerase I elongation complex.
Cell Discov, 7, 2021
4F6M
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Crystal structure of Kaiso zinc finger DNA binding domain in complex with Kaiso binding site DNA
分子名称: DNA (5'-D(*CP*GP*TP*TP*AP*TP*TP*GP*GP*CP*AP*GP*GP*AP*AP*GP*CP*AP*C)-3'), DNA (5'-D(*GP*TP*GP*CP*TP*TP*CP*CP*TP*GP*CP*CP*AP*AP*TP*AP*AP*CP*G)-3'), Transcriptional regulator Kaiso, ...
著者Buck-Koehntop, B.A, Stanfield, R.L, Ekiert, D.C, Martinez-Yamout, M.A, Dyson, H.J, Wilson, I.A, Wright, P.E.
登録日2012-05-15
公開日2012-09-05
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Molecular basis for recognition of methylated and specific DNA sequences by the zinc finger protein Kaiso.
Proc.Natl.Acad.Sci.USA, 109, 2012
7TUJ
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BU of 7tuj by Molmil
NMR solution structure of the phosphorylated MUS81-binding region from human SLX4
分子名称: Structure-specific endonuclease subunit SLX4
著者Payliss, B.J, Reichheld, S.E, Lemak, A, Arrowsmith, C.H, Sharpe, S, Wyatt, H.D.M.
登録日2022-02-02
公開日2022-10-19
最終更新日2022-11-09
実験手法SOLUTION NMR
主引用文献Phosphorylation of the DNA repair scaffold SLX4 drives folding of the SAP domain and activation of the MUS81-EME1 endonuclease.
Cell Rep, 41, 2022
7TOR
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BU of 7tor by Molmil
Mammalian 80S ribosome bound with the ALS/FTD-associated dipeptide repeat protein GR20
分子名称: 18S rRNA, 28S rRNA, 40S ribosomal protein S10, ...
著者Loveland, A.B, Svidritskiy, E, Susorov, D, Lee, S, Park, A, Zvornicanin, S, Demo, G, Gao, F.B, Korostelev, A.A.
登録日2022-01-24
公開日2022-05-25
最終更新日2022-06-01
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Ribosome inhibition by C9ORF72-ALS/FTD-associated poly-PR and poly-GR proteins revealed by cryo-EM.
Nat Commun, 13, 2022
7V99
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catalytic core of human telomerase holoenzyme
分子名称: Histone H2A type 1-B/E, Histone H2B type 1-K, Primer DNA, ...
著者Wan, F, Ding, Y, Yang, L, Wu, Z, Wu, J, Lei, M.
登録日2021-08-24
公開日2022-03-30
実験手法ELECTRON MICROSCOPY (3.54 Å)
主引用文献Zipper head mechanism of telomere synthesis by human telomerase.
Cell Res., 31, 2021
4G0V
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BU of 4g0v by Molmil
Human topoisomerase iibeta in complex with DNA and mitoxantrone
分子名称: 1,4-DIHYDROXY-5,8-BIS({2-[(2-HYDROXYETHYL)AMINO]ETHYL}AMINO)-9,10-ANTHRACENEDIONE, DNA (5'-D(P*AP*GP*CP*CP*GP*AP*GP*C)-3'), DNA (5'-D(P*TP*GP*CP*AP*GP*CP*TP*CP*GP*GP*CP*T)-3'), ...
著者Wu, C.C, Li, T.K, Li, Y.C, Chan, N.L.
登録日2012-07-10
公開日2013-07-17
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.548 Å)
主引用文献On the structural basis and design guidelines for type II topoisomerase-targeting anticancer drugs
Nucleic Acids Res., 41, 2013
4G1N
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BU of 4g1n by Molmil
PKM2 in complex with an activator
分子名称: MAGNESIUM ION, N-(4-{[4-(pyrazin-2-yl)piperazin-1-yl]carbonyl}phenyl)quinoline-8-sulfonamide, OXALATE ION, ...
著者Kung, C, Hixon, J, Dang, L, DeLaBarre, B, Qian, K.C.
登録日2012-07-10
公開日2012-10-10
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Small Molecule Activation of PKM2 in Cancer Cells Induces Serine Auxotrophy.
Chem.Biol., 19, 2012
4F3L
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BU of 4f3l by Molmil
Crystal Structure of the Heterodimeric CLOCK:BMAL1 Transcriptional Activator Complex
分子名称: BMAL1b, Circadian locomoter output cycles protein kaput
著者Huang, N, Chelliah, Y, Shan, Y, Taylor, C, Yoo, S, Partch, C, Green, C.B, Zhang, H, Takahashi, J.
登録日2012-05-09
公開日2012-06-06
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.268 Å)
主引用文献Crystal structure of the heterodimeric CLOCK:BMAL1 transcriptional activator complex.
Science, 337, 2012
7V1M
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BU of 7v1m by Molmil
Structural basis for the co-chaperone relationship of sNASP and ASF1b
分子名称: Histone H3.3, Histone H4, Histone chaperone ASF1B, ...
著者Bao, H, Huang, H.
登録日2021-08-04
公開日2022-04-20
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.834 Å)
主引用文献NASP maintains histone H3-H4 homeostasis through two distinct H3 binding modes.
Nucleic Acids Res., 50, 2022
7UCJ
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BU of 7ucj by Molmil
Mammalian 80S translation initiation complex with mRNA and Harringtonine
分子名称: 18S rRNA, 28s rRNA, 40S ribosomal protein S10, ...
著者Yang, R, Arango, D, Sturgill, D, Oberdoerffer, S.
登録日2022-03-16
公開日2022-06-01
最終更新日2022-08-17
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Direct epitranscriptomic regulation of mammalian translation initiation through N4-acetylcytidine.
Mol.Cell, 82, 2022
4FM9
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BU of 4fm9 by Molmil
Human topoisomerase II alpha bound to DNA
分子名称: DNA (5'-D(*CP*GP*CP*GP*CP*AP*TP*CP*GP*TP*CP*AP*TP*CP*CP*TP*C)-3'), DNA (5'-D(P*GP*AP*GP*GP*AP*TP*GP*AP*CP*GP*AP*TP*G)-3'), DNA topoisomerase 2-alpha, ...
著者Wendorff, T.J, Schmidt, B.H, Heslop, P, Austin, C.A, Berger, J.M.
登録日2012-06-15
公開日2012-08-08
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.901 Å)
主引用文献The Structure of DNA-Bound Human Topoisomerase II Alpha: Conformational Mechanisms for Coordinating Inter-Subunit Interactions with DNA Cleavage.
J.Mol.Biol., 424, 2012
7V90
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BU of 7v90 by Molmil
Telomeric mononucleosome
分子名称: DNA (145-mer), Histone H2A type 1-B/E, Histone H2B type 1-K, ...
著者Soman, A.
登録日2021-08-24
公開日2022-07-27
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Columnar structure of human telomeric chromatin.
Nature, 609, 2022
7VA4
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Telomeric tetranucleosome in open state
分子名称: DNA (539-MER), Histone H2A type 1-B/E, Histone H2B type 1-K, ...
著者Soman, A.
登録日2021-08-27
公開日2022-07-27
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (14 Å)
主引用文献Columnar structure of human telomeric chromatin.
Nature, 609, 2022
7V9J
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Telomeric trinucleosome
分子名称: DNA (408-mer), Histone H2A type 1-B/E, Histone H2B type 1-K, ...
著者Soman, A.
登録日2021-08-25
公開日2022-07-27
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (8 Å)
主引用文献Columnar structure of human telomeric chromatin.
Nature, 609, 2022
7V9S
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Telomeric trinucleosome in open state
分子名称: DNA (408-MER), Histone H2A type 1-B/E, Histone H2B type 1-K, ...
著者Soman, A.
登録日2021-08-26
公開日2022-07-27
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (11 Å)
主引用文献Columnar structure of human telomeric chromatin.
Nature, 609, 2022
7V9C
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BU of 7v9c by Molmil
Telomeric Dinucleosome in open state
分子名称: DNA (275-mer), Histone H2A type 1-B/E, Histone H2B type 1-K, ...
著者Soman, A.
登録日2021-08-24
公開日2022-07-27
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (4.5 Å)
主引用文献Columnar structure of human telomeric chromatin.
Nature, 609, 2022
7V9K
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BU of 7v9k by Molmil
Telomeric tetranucleosome
分子名称: DNA (539-mer), Histone H2A type 1-B/E, Histone H2B type 1-K, ...
著者Soman, A.
登録日2021-08-25
公開日2022-07-27
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (8.1 Å)
主引用文献Columnar structure of human telomeric chromatin.
Nature, 609, 2022
7V96
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BU of 7v96 by Molmil
Telomeric Dinucleosome
分子名称: DNA (275-mer), Histone H2A type 1-B/E, Histone H2B type 1-K, ...
著者Soman, A.
登録日2021-08-24
公開日2022-07-27
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (3.92 Å)
主引用文献Columnar structure of human telomeric chromatin.
Nature, 609, 2022
7VCQ
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structure of viral protein BKRF4 in complex with H3.3-H4-ASF1
分子名称: Histone H3.3, Histone H4, Histone chaperone ASF1B, ...
著者Liu, Y.R.
登録日2021-09-03
公開日2022-08-03
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Epstein-Barr Virus Tegument Protein BKRF4 is a Histone Chaperone.
J.Mol.Biol., 434, 2022

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