6YLG
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5YQG
| The structure of 14-3-3 and pNumb peptide | 分子名称: | 14-3-3 protein eta, Peptide from Protein numb homolog | 著者 | Chen, X, Liu, Z, Wen, W. | 登録日 | 2017-11-06 | 公開日 | 2018-02-07 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structural determinants controlling 14-3-3 recruitment to the endocytic adaptor Numb and dissociation of the Numb/alpha-adaptin complex. J. Biol. Chem., 293, 2018
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5YBU
| Structure of the KANK1 ankyrin domain in complex with KIF21A peptide | 分子名称: | KN motif and ankyrin repeat domain-containing protein 1, Kinesin-like protein KIF21A | 著者 | Guo, Q, Liao, S, Min, J, Xu, C, Structural Genomics Consortium (SGC) | 登録日 | 2017-09-05 | 公開日 | 2017-12-06 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.89 Å) | 主引用文献 | Structural basis for the recognition of kinesin family member 21A (KIF21A) by the ankyrin domains of KANK1 and KANK2 proteins. J. Biol. Chem., 293, 2018
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4WHE
| Crystal structure of E. coli phage shock protein A (PspA 1-144) | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Phage shock protein A | 著者 | Parthier, C, Schoepfel, M, Stubbs, M.T, Osadnik, H, Brueser, T. | 登録日 | 2014-09-22 | 公開日 | 2015-09-02 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | PspF-binding domain PspA1-144 and the PspAF complex: New insights into the coiled-coil-dependent regulation of AAA+ proteins. Mol.Microbiol., 98, 2015
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7WUG
| GID subcomplex: Gid12 bound Substrate Receptor Scaffolding module | 分子名称: | Glucose-induced degradation protein 8, HLJ1_G0042170.mRNA.1.CDS.1, Vacuolar import and degradation protein 24, ... | 著者 | Qiao, S, Cheng, J.D, Schulman, B.A. | 登録日 | 2022-02-08 | 公開日 | 2022-06-08 | 最終更新日 | 2024-06-26 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Cryo-EM structures of Gid12-bound GID E3 reveal steric blockade as a mechanism inhibiting substrate ubiquitylation. Nat Commun, 13, 2022
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7WH3
| Solution structure of human stomatin SPFH domain in a phosphate buffer | 分子名称: | Stomatin | 著者 | Kataoka, K, Tenno, T, Goda, N, Hibino, E, Hiroaki, H. | 登録日 | 2021-12-29 | 公開日 | 2022-06-08 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | A cryptic phosphate-binding pocket on the SPFH domain of human stomatin that regulates a novel fibril-like self-assembly Curr Res Struct Biol, 4, 2022
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5YST
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5YSU
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5YRO
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5YTB
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8A8F
| Crystal structure of Glc7 phosphatase in complex with the regulatory region of Ref2 | 分子名称: | MANGANESE (II) ION, PHOSPHATE ION, RNA end formation protein 2, ... | 著者 | Carminati, M, Manav, C.M, Bellini, D, Passmore, L.A. | 登録日 | 2022-06-22 | 公開日 | 2023-11-29 | 最終更新日 | 2024-06-12 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | A direct interaction between CPF and RNA Pol II links RNA 3' end processing to transcription. Mol.Cell, 83, 2023
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6ZFE
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6Z7U
| Myosin-II motor domain complexed with blebbistatin in a new ADP-release conformation | 分子名称: | (-)-1-PHENYL-1,2,3,4-TETRAHYDRO-4-HYDROXYPYRROLO[2,3-B]-7-METHYLQUINOLIN-4-ONE, 1,2-ETHANEDIOL, ADENOSINE-5'-DIPHOSPHATE, ... | 著者 | Ewert, W, Preller, M. | 登録日 | 2020-06-01 | 公開日 | 2020-10-21 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.58 Å) | 主引用文献 | Structural and Computational Insights into a Blebbistatin-Bound Myosin•ADP Complex with Characteristics of an ADP-Release Conformation along the Two-Step Myosin Power Stoke. Int J Mol Sci, 21, 2020
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4WSN
| Crystal structure of the COP9 signalosome, a P1 crystal form | 分子名称: | COP9 signalosome complex subunit 1, COP9 signalosome complex subunit 2, COP9 signalosome complex subunit 3, ... | 著者 | Bunker, R.D, Lingaraju, G.M, Thoma, N.H. | 登録日 | 2014-10-28 | 公開日 | 2015-12-23 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (5.5 Å) | 主引用文献 | Cullin-RING ubiquitin E3 ligase regulation by the COP9 signalosome. Nature, 531, 2016
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6ZDY
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7WV9
| Allosteric modulator ZCZ011 binding to CP55940-bound cannabinoid receptor 1 in complex with Gi protein | 分子名称: | 2-[(1R,2R,5R)-5-hydroxy-2-(3-hydroxypropyl)cyclohexyl]-5-(2-methyloctan-2-yl)phenol, 6-methyl-3-[(1S)-2-nitro-1-thiophen-2-yl-ethyl]-2-phenyl-1H-indole, Cannabinoid receptor 1, ... | 著者 | Xu, Z, Shao, Z. | 登録日 | 2022-02-10 | 公開日 | 2022-06-15 | 最終更新日 | 2024-04-03 | 実験手法 | ELECTRON MICROSCOPY (3.36 Å) | 主引用文献 | Molecular mechanism of allosteric modulation for the cannabinoid receptor CB1. Nat.Chem.Biol., 18, 2022
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4WVD
| Identification of a novel FXR ligand that regulates metabolism | 分子名称: | (2aE,4E,5'S,6S,6'R,7S,8E,11R,13R,15S,17aR,20R,20aR,20bS)-6'-[(2S)-butan-2-yl]-20,20b-dihydroxy-5',6,8,19-tetramethyl-17 -oxo-3',4',5',6,6',10,11,14,15,17,17a,20,20a,20b-tetradecahydro-2H,7H-spiro[11,15-methanofuro[4,3,2-pq][2,6]benzodioxacy clooctadecine-13,2'-pyran]-7-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-alpha-L-arabino-hexopyranosyl)-3-O-methyl-alpha-L-arabino-hexopyranoside, Bile acid receptor, FORMIC ACID, ... | 著者 | Wang, R, Li, Y. | 登録日 | 2014-11-05 | 公開日 | 2015-02-11 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | The antiparasitic drug ivermectin is a novel FXR ligand that regulates metabolism. Nat Commun, 4, 2013
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6Z2S
| Crystal structure of adhibin analogue-bound myosin-2 | 分子名称: | 3,6-dibromo-1-(hydroxymethyl)carbazole, ACETATE ION, ADP METAVANADATE, ... | 著者 | Ewert, W, Knoelker, H.-J, Tsiavaliaris, G, Preller, M. | 登録日 | 2020-05-18 | 公開日 | 2021-06-09 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | The synthetic carbazole adhibin acts as selective myosin class-IX inhibitor in lung cancer cells To Be Published
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6A3A
| MVM NES mutant Nm2 in complex with CRM1-Ran-RanBP1 | 分子名称: | 1,2-ETHANEDIOL, Exportin-1, GLYCEROL, ... | 著者 | Sun, Q, Li, Y. | 登録日 | 2018-06-15 | 公開日 | 2019-06-19 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Cancer Therapy with Nanoparticle-Medicated Intracellular Expression of Peptide CRM1-Inhibitor. Int J Nanomedicine, 16, 2021
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8ARD
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6A3E
| MVM NES mutant Nm15 in complex with CRM1-Ran-RanBP1 | 分子名称: | Exportin-1, GTP-binding nuclear protein Ran, GUANOSINE-5'-TRIPHOSPHATE, ... | 著者 | Sun, Q, Li, Y. | 登録日 | 2018-06-15 | 公開日 | 2019-06-19 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Cancer Therapy with Nanoparticle-Medicated Intracellular Expression of Peptide CRM1-Inhibitor. Int J Nanomedicine, 16, 2021
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6A3C
| MVM NES mutant Nm12 in complex with CRM1-Ran-RanBP1 | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, Exportin-1, ... | 著者 | Sun, Q, Li, Y. | 登録日 | 2018-06-15 | 公開日 | 2019-06-19 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | Cancer Therapy with Nanoparticle-Medicated Intracellular Expression of Peptide CRM1-Inhibitor. Int J Nanomedicine, 16, 2021
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6A3B
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6AK2
| Crystal structure of the syntenin PDZ1 domain in complex with the peptide inhibitor KSL-128018 | 分子名称: | Syntenin-1, peptide inhibitor KSL-128018 | 著者 | Jin, Z.Y, Park, J.H, Yun, J.H, Haugaard-Kedstrom, L.M, Lee, W.T. | 登録日 | 2018-08-29 | 公開日 | 2019-09-04 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.868 Å) | 主引用文献 | A High-Affinity Peptide Ligand Targeting Syntenin Inhibits Glioblastoma. J.Med.Chem., 64, 2021
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7Y1R
| Human L-TGF-beta1 in complex with the anchor protein LRRC33 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Duan, Z, Zhang, Z. | 登録日 | 2022-06-08 | 公開日 | 2022-08-31 | 最終更新日 | 2022-09-07 | 実験手法 | ELECTRON MICROSCOPY (4.01 Å) | 主引用文献 | Specificity of TGF-beta 1 signal designated by LRRC33 and integrin alpha V beta 8. Nat Commun, 13, 2022
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