PDB: 36840 件ウェブページステータス検索Chemie searchBIRD

---

6RON	Endothiapepsin in complex with compound 046 分子名称: DIMETHYL SULFOXIDE, Endothiapepsin, GLYCEROL, ... 著者 Magari, F, Heine, A, Klebe, G. 登録日 2019-05-13 公開日 2020-07-08 実験手法 X-RAY DIFFRACTION (1.15 Å) 主引用文献 Endothiapepsin in complex with compound 046 To Be Published
3MVL	P38 Alpha Map Kinase complexed with pyrrolotriazine inhibitor 7K 分子名称: 4-{[5-(cyclopropylcarbamoyl)-2-methylphenyl]amino}-5-methyl-N-propylpyrrolo[2,1-f][1,2,4]triazine-6-carboxamide, Mitogen-activated protein kinase 14 著者 Sack, J.S. 登録日 2010-05-04 公開日 2010-10-13 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Discovery of 4-(5-(Cyclopropylcarbamoyl)-2-Methylphenylamino)-5-Methyl-Npropylpyrrolo[1,2-F][1,2,4] Triazine-6-Carboxamide (Bms-582949), a Clinical P38 Map Kinase Inhibitor for the Treatment of Inflammatory Diseases J.Med.Chem., 53, 2010
3MW1	p38 kinase Crystal structure in complex with small molecule inhibitor 分子名称: 8-(2,6-dichlorophenyl)-4-(2,4-difluorophenyl)-2-piperidin-4-yl-1,7-naphthyridine 7-oxide, Mitogen-activated protein kinase 14 著者 Segarra, V, Caturla, F, Lumeras, W, Roca, R, Fisher, M, Lamers, M. 登録日 2010-05-05 公開日 2011-04-27 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 1,7-Naphthyridine 1-Oxides as Novel Potent and Selective Inhibitors of p38 Mitogen Activated Protein Kinase J.Med.Chem., 54, 2011
3MVR	Crystal Structure of cytochrome P450 2B4-H226Y in a closed conformation 分子名称: 5-CYCLOHEXYL-1-PENTYL-BETA-D-MALTOSIDE, Cytochrome P450 2B4, PROTOPORPHYRIN IX CONTAINING FE 著者 Shah, M.B, Stout, C.D, Halpert, J.R. 登録日 2010-05-04 公開日 2010-09-29 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.76 Å) 主引用文献 Plasticity of Cytochrome P450 2B4 as Investigated by Hydrogen-Deuterium Exchange Mass Spectrometry and X-ray Crystallography. J.Biol.Chem., 285, 2010
4ZY6	Crystal structure of P21-activated kinase 1 in complex with an inhibitor compound 29 分子名称: N~2~-[(7-chloro-1H-benzimidazol-6-yl)methyl]-N~4~-(5-cyclopropyl-1H-pyrazol-3-yl)pyrimidine-2,4-diamine, SULFATE ION, Serine/threonine-protein kinase PAK 1 著者 Rouge, L, Wang, W. 登録日 2015-05-21 公開日 2015-07-01 最終更新日 2015-12-16 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Structure-Guided Design of Group I Selective p21-Activated Kinase Inhibitors. J.Med.Chem., 58, 2015
6RT1	Native tetragonal lysozyme - home source data 分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, Lysozyme C, ... 著者 Pereira, P.J.B. 登録日 2019-05-22 公開日 2019-05-29 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.336 Å) 主引用文献 Protein crystals as a key for deciphering macromolecular crowding effects on biological reactions. Phys Chem Chem Phys, 22, 2020
3MWZ	Crystal structure of the selenomethionine derivative of the L 22,47,100 M mutant of sialostatin L2 分子名称: SULFATE ION, sialostatin L2 著者 Andersen, J.F. 登録日 2010-05-06 公開日 2010-07-14 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (1.52 Å) 主引用文献 The crystal structures of two salivary cystatins from the tick Ixodes scapularis and the effect of these inhibitors on the establishment of Borrelia burgdorferi infection in a murine model. Mol.Microbiol., 77, 2010
3MWS	Crystal Structure of Group N HIV-1 Protease 分子名称: (3R,3AS,6AR)-HEXAHYDROFURO[2,3-B]FURAN-3-YL(1S,2R)-3-[[(4-AMINOPHENYL)SULFONYL](ISOBUTYL)AMINO]-1-BENZYL-2-HYDROXYPROPYLCARBAMATE, CHLORIDE ION, HIV-1 Protease 著者 Sayer, J.M, Agniswamy, J, Weber, I.T, Louis, J.M. 登録日 2010-05-06 公開日 2011-03-23 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.09 Å) 主引用文献 Autocatalytic maturation, physical/chemical properties, and crystal structure of group N HIV-1 protease: relevance to drug resistance. Protein Sci., 19, 2010
3MX8	Crystal structure of ribonuclease A tandem enzymes and their interaction with the cytosolic ribonuclease inhibitor 分子名称: CHLORIDE ION, Ribonuclease pancreatic, LINKER, ... 著者 Leich, F, Neumann, P, Lilie, H, Ulbrich-Hofmann, R, Arnold, U. 登録日 2010-05-07 公開日 2011-02-09 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Crystal structure of RNase A tandem enzymes and their interaction with the cytosolic ribonuclease inhibitor Febs J., 278, 2011
3MXH	Native structure of a c-di-GMP riboswitch from V. cholerae 分子名称: 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), MAGNESIUM ION, U1 small nuclear ribonucleoprotein A, ... 著者 Strobel, S.A, Smith, K.D. 登録日 2010-05-07 公開日 2010-08-25 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structural and biochemical determinants of ligand binding by the c-di-GMP riboswitch . Biochemistry, 49, 2010
6ROZ	Structure of the N-SH2 domain of the human tyrosine-protein phosphatase non-receptor type 11 in complex with the phosphorylated immune receptor tyrosine-based switch motif 分子名称: Tyrosine-protein phosphatase non-receptor type 11, immune receptor tyrosine-based switch motif (ITSM) 著者 Krausze, J, Sikorska, J, Carlomagno, T. 登録日 2019-05-13 公開日 2020-02-19 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.89 Å) 主引用文献 Molecular mechanism of SHP2 activation by PD-1 stimulation. Sci Adv, 6, 2020
3MYG	Aurora A Kinase complexed with SCH 1473759 分子名称: 2-{ethyl[(5-{[6-methyl-3-(1H-pyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]amino}isothiazol-3-yl)methyl]amino}-2-methylpropan-1-ol, Serine/threonine-protein kinase 6, TETRAETHYLENE GLYCOL 著者 Hruza, A, Prosis, W, Ramanathan, L. 登録日 2010-05-10 公開日 2010-07-21 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Discovery of a Potent, Injectable Inhibitor of Aurora Kinases Based on the Imidazo-[1,2-a]-Pyrazine Core. ACS Med Chem Lett, 1, 2010
6RP5	Crystal structure of monocarboxylated hemoglobin from the sub-Antarctic fish Eleginops maclovinus 分子名称: CARBON MONOXIDE, DITHIONITE, Hemoglobin subunit alpha 1, ... 著者 Balasco, N, Vitagliano, L, Merlino, A, Verde, C, Mazzarella, L, Vergara, A. 登録日 2019-05-13 公開日 2019-12-25 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.49 Å) 主引用文献 The unique structural features of carbonmonoxy hemoglobin from the sub-Antarctic fish Eleginops maclovinus. Sci Rep, 9, 2019
3MYN	Mutation of Methionine-86 in Dehaloperoxidase-hemoglobin: Effects of the Asp-His-Fe Triad in a 3/3 Globin 分子名称: CYANIDE ION, Dehaloperoxidase A, PROTOPORPHYRIN IX CONTAINING FE, ... 著者 Bowden, E.F, de Serrano, V.S, D'Antonio, E.L, Franzen, S. 登録日 2010-05-10 公開日 2011-04-20 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.194 Å) 主引用文献 Functional consequences of the creation of an Asp-His-Fe triad in a 3/3 globin. Biochemistry, 50, 2011
6RQ4	Inhibitor of ERK2 分子名称: 6,6-dimethyl-2-[2-[(2-methylpyrazol-3-yl)amino]pyrimidin-4-yl]-5-(2-morpholin-4-ylethyl)thieno[2,3-c]pyrrol-4-one, Mitogen-activated protein kinase 1, SULFATE ION 著者 O'Reilly, M. 登録日 2019-05-15 公開日 2019-12-04 最終更新日 2020-02-19 実験手法 X-RAY DIFFRACTION (1.96 Å) 主引用文献 Dual-Mechanism ERK1/2 Inhibitors Exploit a Distinct Binding Mode to Block Phosphorylation and Nuclear Accumulation of ERK1/2. Mol.Cancer Ther., 19, 2020
6RQE	CYP121 in complex with 3-acetylene dicyclotyrosine 分子名称: 3-acetylene dicyclotyrosine, Mycocyclosin synthase, PROTOPORPHYRIN IX CONTAINING FE, ... 著者 Poddar, H, Levy, C. 登録日 2019-05-15 公開日 2020-04-22 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.37 Å) 主引用文献 Structure-Activity Relationships ofcyclo(l-Tyrosyl-l-tyrosine) Derivatives Binding toMycobacterium tuberculosisCYP121: Iodinated Analogues Promote Shift to High-Spin Adduct. J.Med.Chem., 62, 2019
3MTL	Crystal structure of the PCTAIRE1 kinase in complex with Indirubin E804 分子名称: (2Z,3E)-2,3'-BIINDOLE-2',3(1H,1'H)-DIONE 3-{O-[(3R)-3,4-DIHYDROXYBUTYL]OXIME}, Cell division protein kinase 16 著者 Krojer, T, Sharpe, T.D, Roos, A, Savitsky, P, Amos, A, Ayinampudi, V, Berridge, G, Fedorov, O, Keates, T, Phillips, C, Burgess-Brown, N, Zhang, Y, Pike, A.C.W, Muniz, J, Vollmar, M, Thangaratnarajah, C, Rellos, P, Ugochukwu, E, Filippakopoulos, P, Yue, W, Das, S, von Delft, F, Edwards, A, Arrowsmith, C.H, Weigelt, J, Bountra, C, Knapp, S, Bullock, A, Structural Genomics Consortium (SGC) 登録日 2010-04-30 公開日 2010-06-09 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Structure and inhibitor specificity of the PCTAIRE-family kinase CDK16. Biochem.J., 474, 2017
4Y3H	Endothiapepsin in complex with fragment 189 分子名称: 2-(pyridin-3-yl)ethanamine, ACETATE ION, Endothiapepsin, ... 著者 Ehrmann, F.R, Heine, A, Klebe, G. 登録日 2015-02-10 公開日 2016-02-17 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.23 Å) 主引用文献 Crystallographic Fragment Sreening of an Entire Library To Be Published
6RUG	Co-substituted alpha-Keggin bound to Proteinase K solved by MR 分子名称: Co-substituted alpha-Keggin, Proteinase K, SULFATE ION 著者 Breibeck, J, Bijelic, A, Rompel, A. 登録日 2019-05-28 公開日 2019-09-18 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.1 Å) 主引用文献 Transition metal-substituted Keggin polyoxotungstates enabling covalent attachment to proteinase K upon co-crystallization. Chem.Commun.(Camb.), 55, 2019
4YH0	Crystal structure of the R111K:Y134F:T54V:R132Q:P39Y:R59Y mutant of human Cellular Retinoic Acid Binding Protein II in complex with Retinal at 2.14 angstrom resolution - UV irradiated crystal - 3rd cycle 分子名称: Cellular retinoic acid-binding protein 2, RETINAL 著者 Nosrati, M, Geiger, J.H. 登録日 2015-02-26 公開日 2016-03-02 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.144 Å) 主引用文献 A Photoisomerizing Rhodopsin Mimic Observed at Atomic Resolution. J.Am.Chem.Soc., 138, 2016
6RUN	Co-substituted alpha-Keggin bound to Proteinase K solved by EP 分子名称: Co-substituted alpha-Keggin, Proteinase K, SULFATE ION 著者 Breibeck, J, Bijelic, A, Rompel, A. 登録日 2019-05-28 公開日 2019-09-18 最終更新日 2019-11-20 実験手法 X-RAY DIFFRACTION (1.1 Å) 主引用文献 Transition metal-substituted Keggin polyoxotungstates enabling covalent attachment to proteinase K upon co-crystallization. Chem.Commun.(Camb.), 55, 2019
9BKF	Crystal structure of selenomethionine labeled bovine trypsin mutant - S195A solved by Sulphur-SAD at 1A wavelength 分子名称: Serine protease 1 著者 Zhou, D, Chen, L, Rose, J.P, Wang, B.C. 登録日 2024-04-27 公開日 2024-06-05 実験手法 X-RAY DIFFRACTION (1.2 Å) 主引用文献 Crystal structure of selenomethionine labeled bovine trypsin mutant - S195A solved by Sulphur-SAD at 1A wavelength To Be Published
4YI9	Crystal structure of non-myristoylated E153A recoverin at 1.35 A resolution with a sodium ion bound to EF-hand 2 and calcium ion bound to EF-hand 3 分子名称: CALCIUM ION, Recoverin, SODIUM ION 著者 Prem Kumar, R, Ranaghan, M.J, Oprian, D.D. 登録日 2015-02-28 公開日 2015-12-02 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.35 Å) 主引用文献 Crystal Structure of Recoverin with Calcium Ions Bound to Both Functional EF Hands. Biochemistry, 54, 2015
4Y51	Endothiapepsin in complex with fragment 52 分子名称: 1,2-ETHANEDIOL, 2-amino-1-(4-bromophenyl)ethanone, Endothiapepsin, ... 著者 Radeva, N, Heine, A, Klebe, G. 登録日 2015-02-11 公開日 2016-03-02 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.603 Å) 主引用文献 Crystallographic Fragment Screening of an Entire Library To Be Published
3MWQ	Crystal structure of ribonuclease A tandem enzymes and their interaction with the cytosolic ribonuclease inhibitor 分子名称: GLYCEROL, Ribonuclease pancreatic, LINKER, ... 著者 Neumann, P, Leich, F. 登録日 2010-05-06 公開日 2011-02-09 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.68 Å) 主引用文献 Crystal structure of RNase A tandem enzymes and their interaction with the cytosolic ribonuclease inhibitor Febs J., 278, 2011

<340341342343344345346347348349350351352353354355>