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2JCA
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Crystal structure of the streptomyces coelicolor holo- [Acyl-carrier-protein] Synthase (AcpS) at 2 A.
分子名称: GLYCEROL, HOLO-[ACYL-CARRIER-PROTEIN] SYNTHASE, SODIUM ION, ...
著者Dall'Aglio, P, Arthur, C, Crump, M.P, Crosby, J, Hadfield, A.T.
登録日2006-12-21
公開日2007-01-30
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.98 Å)
主引用文献Analysis of Streptomyces Coelicolor Phosphopantetheinyl Transferase, Acps, Reveals the Basis for Relaxed Substrate Specificity.
Biochemistry, 50, 2011
2JBY
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A viral protein unexpectedly mimics the structure and function of pro- survival Bcl-2
分子名称: BCL-2 HOMOLOGOUS ANTAGONIST/KILLER 2, M11L PROTEIN, SODIUM ION
著者Kvansakul, M, Van Delft, M.F, Lee, E.F, Gulbis, J.M, Fairlie, W.D, Huang, D.C.S, Colman, P.M.
登録日2006-12-14
公開日2007-03-27
最終更新日2018-06-13
実験手法X-RAY DIFFRACTION (2.41 Å)
主引用文献A structural viral mimic of prosurvival Bcl-2: a pivotal role for sequestering proapoptotic Bax and Bak.
Mol. Cell, 25, 2007
1W7V
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ZnMg substituted aminopeptidase P from E. coli
分子名称: CHLORIDE ION, MAGNESIUM ION, PEPTIDE VAL-PRO-LEU, ...
著者Graham, S.C, Bond, C.S, Freeman, H.C, Guss, J.M.
登録日2004-09-13
公開日2005-09-29
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural and Functional Implications of Metal Ion Selection in Aminopeptidase P, a Metalloprotease with a Dinuclear Metal Center.
Biochemistry, 44, 2005
2JJA
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Crystal structure of GNA with synthetic copper base pair
分子名称: COBALT HEXAMMINE(III), COPPER (II) ION, GNA, ...
著者Schlegel, M.K, Essen, L.-O, Meggers, E.
登録日2008-03-28
公開日2008-07-22
最終更新日2024-06-19
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Duplex Structure of a Minimal Nucleic Acid.
J.Am.Chem.Soc., 130, 2008
2IEN
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Crystal structure analysis of HIV-1 protease with a potent non-peptide inhibitor (UIC-94017)
分子名称: (3R,3AS,6AR)-HEXAHYDROFURO[2,3-B]FURAN-3-YL(1S,2R)-3-[[(4-AMINOPHENYL)SULFONYL](ISOBUTYL)AMINO]-1-BENZYL-2-HYDROXYPROPYLCARBAMATE, ACETIC ACID, CHLORIDE ION, ...
著者Tie, Y, Boross, P.I, Wang, Y.F, Gaddis, L, Manna, D, Hussain, A.K, Leshchenko, S, Ghosh, A.K, Louis, J.M, Harrison, R.W, Weber, I.T.
登録日2006-09-19
公開日2006-10-03
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献High Resolution Crystal Structures of HIV-1 Protease with a Potent Non-Peptide Inhibitor (Uic-94017) Active Against Multi-Drug-Resistant Clinical Strains.
J.Mol.Biol., 338, 2004
1W4N
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AGAO covalent complex with Tranylcypromine
分子名称: COPPER (II) ION, GLYCEROL, PHENYLETHYLAMINE OXIDASE, ...
著者Duff, A.P, Trambaiolo, D.M, Langley, D.B, Juda, G.A, Shepard, E.M, Dooley, D.M, Freeman, H.C, Guss, J.M.
登録日2004-07-27
公開日2005-12-08
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Complexes of the Copper-Containing Amine Oxidase from Arthrobacter Globiformis with the Inhibitors Benzylhydrazine and Tranylcypromine.
Acta Crystallogr.,Sect.F, 64, 2008
2IEO
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Crystal structure analysis of HIV-1 protease mutant I84V with a potent non-peptide inhibitor (UIC-94017)
分子名称: (3R,3AS,6AR)-HEXAHYDROFURO[2,3-B]FURAN-3-YL(1S,2R)-3-[[(4-AMINOPHENYL)SULFONYL](ISOBUTYL)AMINO]-1-BENZYL-2-HYDROXYPROPYLCARBAMATE, CHLORIDE ION, Protease, ...
著者Tie, Y, Boross, P.I, Wang, Y.F, Gaddis, L, Manna, D, Hussain, A.K, Leshchenko, S, Ghosh, A.K, Louis, J.M, Harrison, R.W, Weber, I.T.
登録日2006-09-19
公開日2006-10-03
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.53 Å)
主引用文献High Resolution Crystal Structures of HIV-1 Protease with a Potent Non-Peptide Inhibitor (Uic-94017) Active Against Multi-Drug-Resistant Clinical Strains.
J.Mol.Biol., 338, 2004
2IM0
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Crystal structure of poliovirus polymerase complexed with CTP and Mg2+
分子名称: ACETIC ACID, CYTIDINE-5'-TRIPHOSPHATE, SODIUM ION, ...
著者Thompson, A.A, Peersen, O.B.
登録日2006-10-03
公開日2006-12-12
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Stabilization of Poliovirus Polymerase by NTP Binding and Fingers-Thumb Interactions.
J.Mol.Biol., 366, 2007
2IDL
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Crystal Structure of Conserved Protein of Unknown Function from Streptococcus pneumoniae
分子名称: GLYCEROL, Hypothetical protein, SODIUM ION
著者Nocek, B, Wu, R, Abdullah, J, Joachimiak, A, Midwest Center for Structural Genomics (MCSG)
登録日2006-09-15
公開日2006-10-17
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Crystal structure of conserved hypothetical protein from Streptococcus pneumoniae TIGR4
To be Published
2JJZ
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Crystal Structure of Human Iba2, orthorhombic crystal form
分子名称: ACETATE ION, CHLORIDE ION, IONIZED CALCIUM-BINDING ADAPTER MOLECULE 2, ...
著者Schulze, J.O, Quedenau, C, Roske, Y, Turnbull, A, Mueller, U, Heinemann, U, Buessow, K.
登録日2008-05-15
公開日2009-07-14
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Structural and Functional Characterization of Human Iba Proteins.
FEBS J., 275, 2008
2IM1
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Crystal structure of poliovirus polymerase complexed with CTP and Mn2+
分子名称: ACETIC ACID, CYTIDINE-5'-TRIPHOSPHATE, MANGANESE (II) ION, ...
著者Thompson, A.A, Peersen, O.B.
登録日2006-10-03
公開日2006-12-12
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Stabilization of Poliovirus Polymerase by NTP Binding and Fingers-Thumb Interactions.
J.Mol.Biol., 366, 2007
2C19
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5-(4-Carboxy-2-oxo-butylsulfanyl)-4-oxo-pentanoic acid acid bound to Porphobilinogen synthase from Pseudomonas aeruginosa
分子名称: DELTA-AMINOLEVULINIC ACID DEHYDRATASE, MAGNESIUM ION, SODIUM ION
著者Frere, F, Nentwich, M, Gacond, S, Heinz, D.W, Neier, R, Frankenberg-Dinkel, N.
登録日2005-09-11
公開日2006-06-20
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Probing the Active Site of Pseudomonas Aeruginosa Porphobilinogen Synthase Using Newly Developed Inhibitors.
Biochemistry, 45, 2006
2J9E
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Structure of GlnK1 with bound effectors indicates regulatory mechanism for ammonia uptake
分子名称: 2-OXOGLUTARIC ACID, ACETATE ION, ADENOSINE-5'-TRIPHOSPHATE, ...
著者Yildiz, O, Kalthoff, C, Raunser, S, Kuehlbrandt, W.
登録日2006-11-07
公開日2007-01-16
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.62 Å)
主引用文献Structure of Glnk1 with Bound Effectors Indicates Regulatory Mechanism for Ammonia Uptake.
Embo J., 26, 2007
2IM3
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Crystal structure of poliovirus polymerase complexed with UTP and Mn2+
分子名称: ACETIC ACID, MANGANESE (II) ION, SODIUM ION, ...
著者Thompson, A.A, Peersen, O.B.
登録日2006-10-03
公開日2006-12-12
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Stabilization of Poliovirus Polymerase by NTP Binding and Fingers-Thumb Interactions.
J.Mol.Biol., 366, 2007
2JIN
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Crystal structure of PDZ domain of Synaptojanin-2 binding protein
分子名称: SODIUM ION, SULFATE ION, SYNAPTOJANIN-2 BINDING PROTEIN
著者Tickle, J, Phillips, C, Pike, A.C.W, Cooper, C, Salah, E, Elkins, J, Turnbull, A.P, Edwards, A, Arrowsmith, C.H, Weigelt, J, Sundstrom, M, Doyle, D.
登録日2007-06-28
公開日2007-07-10
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Crystal Structure of Pdz Domain of Synaptojanin-2 Binding Protein
To be Published
2I1N
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Crystal structure of the 1st PDZ domain of Human DLG3
分子名称: Discs, large homolog 3, SODIUM ION
著者Turnbull, A.P, Phillips, C, Bunkoczi, G, Debreczeni, J, Ugochukwu, E, Pike, A.C.W, Gorrec, F, Umeano, C, Elkins, J, Berridge, G, Savitsky, P, Gileadi, O, von Delft, F, Weigelt, J, Edwards, A, Arrowsmith, C, Sundstrom, M, Doyle, D, Structural Genomics Consortium (SGC)
登録日2006-08-14
公開日2006-09-05
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Structure of PICK1 and other PDZ domains obtained with the help of self-binding C-terminal extensions.
Protein Sci., 16, 2007
2IAJ
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Crystal Structure of K103N/Y181C Mutant HIV-1 Reverse Transcriptase (RT) in Complex with ATP
分子名称: ADENOSINE-5'-TRIPHOSPHATE, GLYCEROL, MANGANESE (II) ION, ...
著者Das, K, Arnold, E.
登録日2006-09-08
公開日2006-12-19
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal Structures of Clinically Relevant Lys103Asn/Tyr181Cys Double Mutant HIV-1 Reverse Transcriptase in Complexes with ATP and Non-nucleoside Inhibitor HBY 097.
J.Mol.Biol., 365, 2007
2IBA
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Urate oxidase from Aspergillus flavus complexed with its inhibitor 8-azaxanthine
分子名称: 8-AZAXANTHINE, SODIUM ION, Uricase
著者Colloc'h, N, Retailleau, P, Sopkova-de Oliveira Santos, J, Prange, T.
登録日2006-09-11
公開日2007-02-06
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Protein Crystallography under Xenon and Nitrous Oxide Pressure: Comparison with In Vivo Pharmacology Studies and Implications for the Mechanism of Inhaled Anesthetic Action
Biophys.J., 92, 2007
2GG3
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Novel bacterial methionine aminopeptidase inhibitors
分子名称: 4-(4-FLUORO-PHENYLAZO)-5-IMINO-5H-PYRAZOL-3-YLAMINE, COBALT (II) ION, Methionine aminopeptidase, ...
著者Evdokimov, A.G, Pokross, M.E, Walter, R.L, Mekel, M.
登録日2006-03-23
公開日2006-06-13
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Serendipitous discovery of novel bacterial methionine aminopeptidase inhibitors.
Proteins, 66, 2007
1XP7
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HIV-1 subtype F genomic RNA Dimerization Initiation Site
分子名称: 5'-R(*CP*UP*UP*GP*CP*UP*GP*AP*AP*GP*UP*GP*CP*AP*CP*AP*CP*AP*GP*CP*AP*AP*G)-3', MAGNESIUM ION, SODIUM ION, ...
著者Ennifar, E, Dumas, P.
登録日2004-10-08
公開日2005-10-18
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Polymorphism of Bulged-out Residues in HIV-1 RNA DIS Kissing Complex and Structure Comparison with Solution Studies
J.Mol.Biol., 356, 2006
2GGC
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Novel bacterial methionine aminopeptidase inhibitors
分子名称: COBALT (II) ION, METHIONINE, Methionine aminopeptidase, ...
著者Evdokimov, A.G, Pokross, M.E, Walter, R.L, Mekel, M.
登録日2006-03-23
公開日2006-06-13
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1 Å)
主引用文献Serendipitous discovery of novel bacterial methionine aminopeptidase inhibitors.
Proteins, 66, 2007
2GIJ
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Q138F HincII bound to cognate DNA GTTAAC and Ca2+
分子名称: 5'-D(*GP*CP*CP*GP*GP*TP*TP*AP*AP*CP*CP*GP*GP*C)-3', CALCIUM ION, SODIUM ION, ...
著者Horton, N.C, Joshi, H.K.
登録日2006-03-28
公開日2006-07-18
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.93 Å)
主引用文献Alteration of Sequence Specificity of the Type II Restriction Endonuclease HincII through an Indirect Readout Mechanism.
J.Biol.Chem., 281, 2006
2GHE
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Conformational mobility in the active site of a heme peroxidase
分子名称: PROTOPORPHYRIN IX CONTAINING FE, SODIUM ION, cytosolic ascorbate peroxidase 1
著者Badyal, S.K, Joyce, M.G, Sharp, K.H, Raven, E.L, Moody, P.C.E.
登録日2006-03-27
公開日2006-06-13
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Conformational Mobility in the Active Site of a Heme Peroxidase.
J.Biol.Chem., 281, 2006
2GIE
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HincII bound to cognate DNA GTTAAC
分子名称: 5'-D(*GP*CP*CP*GP*GP*TP*TP*AP*AP*CP*CP*GP*G)-3', SODIUM ION, Type II restriction enzyme HincII
著者Horton, N.C, Joshi, H.K, Etzkorn, C, Chatwell, L, Bitinaite, J.
登録日2006-03-28
公開日2006-07-18
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Alteration of Sequence Specificity of the Type II Restriction Endonuclease HincII through an Indirect Readout Mechanism.
J.Biol.Chem., 281, 2006
2GN2
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Crystal structure of tetrameric biodegradative threonine deaminase (TdcB) from Salmonella typhimurium in complex with CMP at 2.5A resolution (Hexagonal form)
分子名称: CYTIDINE-5'-MONOPHOSPHATE, SODIUM ION, Threonine dehydratase catabolic
著者Simanshu, D.K, Savithri, H.S, Murthy, M.R.N.
登録日2006-04-09
公開日2006-11-07
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal structures of Salmonella typhimurium biodegradative threonine deaminase and its complex with CMP provide structural insights into ligand-induced oligomerization and enzyme activation.
J.Biol.Chem., 281, 2006

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