PDB: 243083 件ウェブページステータス検索Chemie searchBIRD

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4G31	Crystal Structure of GSK6414 Bound to PERK (R587-R1092, delete A660-T867) at 2.28 A Resolution 分子名称: 1-[5-(4-amino-7-methyl-7H-pyrrolo[2,3-d]pyrimidin-5-yl)-2,3-dihydro-1H-indol-1-yl]-2-[3-(trifluoromethyl)phenyl]ethanone, Eukaryotic translation initiation factor 2-alpha kinase 3, GLYCEROL 著者 Gampe, R.T, Axten, J.M. 登録日 2012-07-13 公開日 2012-08-08 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.28 Å) 主引用文献 Discovery of 7-Methyl-5-(1-{[3-(trifluoromethyl)phenyl]acetyl}-2,3-dihydro-1H-indol-5-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine (GSK2606414), a Potent and Selective First-in-Class Inhibitor of Protein Kinase R (PKR)-like Endoplasmic Reticulum Kinase (PERK). J.Med.Chem., 55, 2012
2HOS	Phage-Selected Homeodomain Bound to Unmodified DNA 分子名称: 3-METHYL-1,3-OXAZOLIDIN-2-ONE, 5'-D(*AP*TP*CP*CP*GP*GP*GP*GP*AP*TP*TP*AP*CP*AP*TP*GP*GP*CP*AP*AP*A)-3', 5'-D(*TP*TP*TP*TP*GP*CP*CP*AP*TP*GP*TP*AP*AP*TP*CP*CP*CP*CP*GP*GP*A)-3', ... 著者 Shokat, K.M, Feldman, M.E, Simon, M.D. 登録日 2006-07-16 公開日 2006-12-12 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structure and properties of a re-engineered homeodomain protein-DNA interface. Acs Chem.Biol., 1, 2006
4GFS	1.8 Angstrom Crystal Structure of the 3-Dehydroquinate Dehydratase (aroD) from Salmonella typhimurium LT2 with Nickel Bound at Active Site 分子名称: 3-dehydroquinate dehydratase, NICKEL (II) ION, SUCCINIC ACID 著者 Light, S.H, Minasov, G, Krishna, S.N, Shuvalova, L, Kwon, K, Lavie, A, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) 登録日 2012-08-03 公開日 2012-08-15 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 1.8 Angstrom Crystal Structure of the 3-Dehydroquinate Dehydratase (aroD) from Salmonella typhimurium LT2 with Nickel Bound at Active Site TO BE PUBLISHED
3UUW	1.63 Angstrom Resolution Crystal Structure of Dehydrogenase (MviM) from Clostridium difficile. 分子名称: CHLORIDE ION, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... 著者 Minasov, G, Wawrzak, Z, Kudritska, M, Grimshaw, S, Papazisi, L, Savchenko, A, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) 登録日 2011-11-28 公開日 2011-12-21 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.63 Å) 主引用文献 1.63 Angstrom Resolution Crystal Structure of Dehydrogenase (MviM) from Clostridium difficile. TO BE PUBLISHED
4KRZ	Apo crystal structure of pyruvate kinase (PYK) from Trypanosoma cruzi 分子名称: GLYCEROL, POTASSIUM ION, Pyruvate kinase 著者 Zhong, W, Morgan, H.P, McNae, I.W, Michels, P.A.M, Fothergill-Gilmore, L.A, Walkinshaw, M.D. 登録日 2013-05-17 公開日 2014-11-19 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structures of pyruvate kinases display evolutionarily divergent allosteric strategies. R Soc Open Sci, 1, 2014
1EMD	CRYSTAL STRUCTURE OF A TERNARY COMPLEX OF ESCHERICHIA COLI MALATE DEHYDROGENASE, CITRATE AND NAD AT 1.9 ANGSTROMS RESOLUTION 分子名称: CITRIC ACID, MALATE DEHYDROGENASE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE 著者 Hall, M.D, Banaszak, L.J. 登録日 1993-03-25 公開日 1993-10-31 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Crystal structure of a ternary complex of Escherichia coli malate dehydrogenase citrate and NAD at 1.9 A resolution. J.Mol.Biol., 232, 1993
2GF3	Structure of the complex of monomeric sarcosine with its substrate analogue inhibitor 2-furoic acid at 1.3 A resolution. 分子名称: 2-FUROIC ACID, CHLORIDE ION, FLAVIN-ADENINE DINUCLEOTIDE, ... 著者 Chen, Z, Trickey, P, Jorns, M.S, Mathews, F.S. 登録日 2006-03-21 公開日 2007-02-06 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 Structure of the complex of monomeric sarcosine with its substrate analogue inhibitor 2-furoic acid at 1.3 A resolution. TO BE PUBLISHED
4ESK	Crystal structure of a strand-swapped dimer of Mouse Leukocyte-associated immunoglobulin-like receptor 1 (NYSGRC-006047)IG-like domain 分子名称: GLYCEROL, Leukocyte-associated immunoglobulin-like receptor 1, POTASSIUM ION, ... 著者 Sampathkumar, P, Almo, S.C, New York Structural Genomics Research Consortium (NYSGRC), Atoms-to-Animals: The Immune Function Network (IFN) 登録日 2012-04-23 公開日 2012-05-02 最終更新日 2024-11-20 実験手法 X-RAY DIFFRACTION (1.762 Å) 主引用文献 Crystal structure of a strand-swapped dimer of Mouse Leukocyte-associated immunoglobulin-like receptor 1 IG-like domain to be published
4E4V	The crystal structure of the dimeric human importin alpha 1 at 2.5 angstrom resolution. 分子名称: 2,3-DIHYDROXY-1,4-DITHIOBUTANE, GLYCEROL, Importin subunit alpha-2 著者 Hang, P.C, Miknis, Z.M, Franke, W.A, Umland, T.C, Schultz, L.W. 登録日 2012-03-13 公開日 2013-05-29 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.5283 Å) 主引用文献 The crystal structure of the dimeric human importin alpha 1 at 2.5 angstrom resolution. To be Published
7DBN	HIV-1 reverse transcriptase mutant Q151M/Y115F/F116Y/M184V/F160M:DNA:dCTP ternary complex 分子名称: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, DNA/RNA (38-MER), GLYCEROL, ... 著者 Yasutake, Y, Hattori, S.I, Tamura, N, Maeda, K. 登録日 2020-10-21 公開日 2021-08-04 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.67 Å) 主引用文献 Biochemical and Structural Properties of Entecavir-Resistant Hepatitis B Virus Polymerase with L180M/M204V Mutations. J.Virol., 95, 2021
1WNB	Escherichia coli YdcW gene product is a medium-chain aldehyde dehydrogenase (complexed with nadh and betaine aldehyde) 分子名称: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, BETAINE ALDEHYDE, Putative betaine aldehyde dehydrogenase 著者 Gruez, A, Roig-Zamboni, V, Tegoni, M, Cambillau, C. 登録日 2004-07-29 公開日 2004-10-05 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Crystal Structure and Kinetics Identify Escherichia coli YdcW Gene Product as a Medium-chain Aldehyde Dehydrogenase J.Mol.Biol., 343, 2004
5DYW	Crystal structure of human butyrylcholinesterase in complex with N-((1-benzylpiperidin-3-yl)methyl)-N-(2-methoxyethyl)naphthalene-2-sulfonamide 分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Coquelle, N, Brus, B, Colletier, J.P. 登録日 2015-09-25 公開日 2017-01-18 最終更新日 2024-11-06 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Development of an in-vivo active reversible butyrylcholinesterase inhibitor. Sci Rep, 6, 2016
4DDM	Pantothenate synthetase in complex with 2,1,3-benzothiadiazole-5-carboxylic acid 分子名称: 1,2-ETHANEDIOL, 2,1,3-benzothiadiazole-5-carboxylic acid, ETHANOL, ... 著者 Silvestre, H.L. 登録日 2012-01-18 公開日 2013-02-13 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.83 Å) 主引用文献 Integrated biophysical approach to fragment screening and validation for fragment-based lead discovery. Proc.Natl.Acad.Sci.USA, 110, 2013
1X0V	Crystal Structure of Homo Sapien Glycerol-3-Phosphate Dehydrogenase 1 分子名称: Glycerol-3-phosphate dehydrogenase [NAD+], cytoplasmic, SULFATE ION 著者 Rao, Z, Ou, X. 登録日 2005-03-30 公開日 2006-04-11 最終更新日 2024-10-30 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Crystal Structures of Human Glycerol 3-phosphate Dehydrogenase 1 (GPD1) J.Mol.Biol., 357, 2006
1BXS	SHEEP LIVER CLASS 1 ALDEHYDE DEHYDROGENASE WITH NAD BOUND 分子名称: ALDEHYDE DEHYDROGENASE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE 著者 Moore, S.A, Baker, H.M, Blythe, T.J, Kitson, K.E, Kitson, T.M, Baker, E.N. 登録日 1998-10-08 公開日 1999-04-27 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 Sheep liver cytosolic aldehyde dehydrogenase: the structure reveals the basis for the retinal specificity of class 1 aldehyde dehydrogenases. Structure, 6, 1998
1GOF	NOVEL THIOETHER BOND REVEALED BY A 1.7 ANGSTROMS CRYSTAL STRUCTURE OF GALACTOSE OXIDASE 分子名称: ACETIC ACID, COPPER (II) ION, GALACTOSE OXIDASE, ... 著者 Ito, N, Phillips, S.E.V, Knowles, P.F. 登録日 1993-09-30 公開日 1994-01-31 最終更新日 2024-10-30 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Novel thioether bond revealed by a 1.7 A crystal structure of galactose oxidase. Nature, 350, 1991
1BMD	DETERMINANTS OF PROTEIN THERMOSTABILITY OBSERVED IN THE 1.9 ANGSTROMS CRYSTAL STRUCTURE OF MALATE DEHYDROGENASE FROM THE THERMOPHILIC BACTERIUM THERMUS FLAVUS 分子名称: MALATE DEHYDROGENASE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE 著者 Kelly, C.A, Birktoft, J.J. 登録日 1992-11-10 公開日 1994-07-31 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Determinants of protein thermostability observed in the 1.9-A crystal structure of malate dehydrogenase from the thermophilic bacterium Thermus flavus. Biochemistry, 32, 1993
3P4T	Crystal structure of a putative acyl-CoA dehydrogenase from Mycobacterium smegmatis 分子名称: 1,2-ETHANEDIOL, Putative acyl-CoA dehydrogenase, [(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methyl (2R,3S,4S)-5-[(4aS,10aR)-7,8-dimethyl-2,4-dioxo-1,3,4,4a,5,10a-hexahydrobenzo[g]pteridin-10(2H)-yl]-2,3,4-trihydroxypentyl dihydrogen diphosphate 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2010-10-07 公開日 2010-10-20 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Increasing the structural coverage of tuberculosis drug targets. Tuberculosis (Edinb), 95, 2015
1GOG	NOVEL THIOETHER BOND REVEALED BY A 1.7 ANGSTROMS CRYSTAL STRUCTURE OF GALACTOSE OXIDASE 分子名称: COPPER (II) ION, GALACTOSE OXIDASE, SODIUM ION 著者 Ito, N, Phillips, S.E.V, Knowles, P.F. 登録日 1993-09-30 公開日 1994-01-31 最終更新日 2024-11-20 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Novel thioether bond revealed by a 1.7 A crystal structure of galactose oxidase. Nature, 350, 1991
3RU6	1.8 Angstrom resolution crystal structure of orotidine 5'-phosphate decarboxylase (pyrF) from Campylobacter jejuni subsp. jejuni NCTC 11168 分子名称: CHLORIDE ION, IODIDE ION, Orotidine 5'-phosphate decarboxylase 著者 Halavaty, A.S, Minasov, G, Shuvalova, L, Dubrovska, I, Winsor, J, Papazisi, L, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) 登録日 2011-05-04 公開日 2011-05-18 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 1.8 Angstrom resolution crystal structure of orotidine 5'-phosphate decarboxylase (pyrF) from Campylobacter jejuni subsp. jejuni NCTC 11168 To be Published
1X0X	Co-Structure of Homo Sapiens Glycerol-3-Phosphate Dehydrogenase 1 complex with NAD 分子名称: Glycerol-3-phosphate dehydrogenase [NAD+], cytoplasmic, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... 著者 Rao, Z, Ou, X. 登録日 2005-03-31 公開日 2006-04-11 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.75 Å) 主引用文献 Crystal Structures of Human Glycerol 3-phosphate Dehydrogenase 1 (GPD1) J.Mol.Biol., 357, 2006
3OZ2	Crystal structure of a geranylgeranyl bacteriochlorophyll reductase-like (Ta0516) from Thermoplasma acidophilum at 1.60 A resolution 分子名称: (2R)-3-{[(R)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-2-[(6Z)-tridec-6-enoyloxy]propyl (9Z)-octadec-9-enoate, 1,2-ETHANEDIOL, Digeranylgeranylglycerophospholipid reductase, ... 著者 Joint Center for Structural Genomics (JCSG) 登録日 2010-09-24 公開日 2010-10-27 最終更新日 2024-10-09 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Insights into substrate specificity of geranylgeranyl reductases revealed by the structure of digeranylgeranylglycerophospholipid reductase, an essential enzyme in the biosynthesis of archaeal membrane lipids. J.Mol.Biol., 404, 2010
5FEC	Crystal structure of 3BNC60 Fab germline precursor in complex with 426c.TM4deltaV1-3 gp120 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 426c.TM4deltaV1-3 gp120, ... 著者 Scharf, L, Bjorkman, P.J. 登録日 2015-12-16 公開日 2016-05-04 最終更新日 2024-11-06 実験手法 X-RAY DIFFRACTION (3.17 Å) 主引用文献 Structural basis for germline antibody recognition of HIV-1 immunogens. Elife, 5, 2016
3RMI	Crystal structure of Chorismate mutase from Bartonella henselae str. Houston-1 in complex with malate 分子名称: 1,2-ETHANEDIOL, Chorismate mutase protein, D-MALATE, ... 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2011-04-20 公開日 2011-05-11 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Crystal structure of Chorismate mutase from Bartonella henselae str. Houston-1 in complex with malate To be Published
5UC6	Structural insights into IL-1 alpha recognition by a naphthyl-modified aptamer that mimics IL-1RI Domain III 分子名称: DNA (5'-D(*CP*G)-R(P*(85Y))-D(P*GP*AP*G)-R(P*(85Y)P*(85Y))-D(P*A)-R(P*(85Y))-D(P*GP*GP*G)-R(P*(85Y)P*(85Y))-D(P*AP*GP*AP*G)-R(P*(85Y))-D(P*CP*GP*(ATD))-3'), Interleukin-1 alpha, MAGNESIUM ION, ... 著者 Ren, X, Pyle, A. 登録日 2016-12-21 公開日 2017-10-11 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structural basis for IL-1 alpha recognition by a modified DNA aptamer that specifically inhibits IL-1 alpha signaling. Nat Commun, 8, 2017

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