PDB: 48062 件ウェブページステータス検索Chemie searchBIRD

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5EGL	The structural and biochemical characterization of acyl-coa hydrolase from Staphylococcus aureus in complex with Butyryl Coenzyme A, Coenzyme A, and Coenzyme A disulfide 分子名称: Acyl CoA Hydrolase, Butyryl Coenzyme A, COENZYME A, ... 著者 Khandokar, Y.B, Srivastava, P.S, Forwood, J.K. 登録日 2015-10-27 公開日 2016-11-09 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 The structural and biochemical characterization of acyl-coa hydrolase from Staphylococcus aureus To Be Published
2ZR1	Agglutinin from Abrus Precatorius 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Agglutinin-1 chain A, Agglutinin-1 chain B 著者 Cheng, J, Lu, T.H, Liu, C.L, Lin, J.Y. 登録日 2008-08-22 公開日 2009-08-25 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 A biophysical elucidation for less toxicity of Agglutinin than Abrin-a from the Seeds of Abrus Precatorius in consequence of crystal structure J.Biomed.Sci., 17, 2010
1PXX	CRYSTAL STRUCTURE OF DICLOFENAC BOUND TO THE CYCLOOXYGENASE ACTIVE SITE OF COX-2 分子名称: 2-[2,6-DICHLOROPHENYL)AMINO]BENZENEACETIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Kiefer, J.R, Rowlinson, S.W, Prusakiewicz, J.J, Pawlitz, J.L, Kozak, K.R, Kalgutkar, A.S, Stallings, W.C, Marnett, L.J, Kurumbail, R.G. 登録日 2003-07-07 公開日 2003-09-09 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 A Novel Mechanism of Cyclooxygenase-2 Inhibition Involving Interactions with Ser-530 and Tyr-385. J.Biol.Chem., 278, 2003
5ENJ	Crystal structure of the second bromodomain of Pleckstrin homology domain interacting protein (PHIP) in complex with compound-14 N11530 (SGC - Diamond I04-1 fragment screening) 分子名称: MAGNESIUM ION, PH-interacting protein, ~{N}-[[2,6-bis(chloranyl)phenyl]methyl]-~{N}-methyl-ethanamide 著者 Krojer, T, Talon, R, Collins, P, Bradley, A, Cox, O, Szykowska, A, Burgess-Brown, N, Brennan, P, Bountra, C, Arrowsmith, C.H, Edwards, A, von Delft, F, Structural Genomics Consortium (SGC) 登録日 2015-11-09 公開日 2016-04-27 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.63 Å) 主引用文献 A poised fragment library enables rapid synthetic expansion yielding the first reported inhibitors of PHIP(2), an atypical bromodomain. Chem Sci, 7, 2016
7Q6V	Crystal structure of the bromodomain of ATAD2 with triazolopyridine (cpd 14) 分子名称: (1R,9S)-13-[(8-azanyl-3-methyl-[1,2,4]triazolo[4,3-a]pyridin-6-yl)carbonyl]-11,13-diazatricyclo[7.3.1.0^{2,7}]trideca-2,4,6-trien-10-one, ATPase family AAA domain-containing protein 2, SULFATE ION 著者 Patel, S.J, Winter-Holt, J.J. 登録日 2021-11-09 公開日 2022-01-19 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (1.96 Å) 主引用文献 Discovery of a Potent and Selective ATAD2 Bromodomain Inhibitor with Antiproliferative Activity in Breast Cancer Models. J.Med.Chem., 65, 2022
4G33	Crystal Structure of a Phospholipid-Lipoxygenase Complex from Pseudomonas aeruginosa at 2.0 A (C2221) 分子名称: (2R)-3-{[(S)-(2-aminoethoxy)(hydroxy)phosphoryl]oxy}-2-(tetradec-5-enoyloxy)propyl (11Z)-octadec-11-enoate, 15S-LIPOXYGENASE, FE (II) ION, ... 著者 Carpena, X, Garreta, A, Val-Moraes, S.P, Garcia-Fernandez, Q, Fita, I. 登録日 2012-07-13 公開日 2013-11-06 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.03 Å) 主引用文献 Structure and interaction with phospholipids of a prokaryotic lipoxygenase from Pseudomonas aeruginosa. Faseb J., 27, 2013
2ZUJ	Crystal Structure of Camphor-soaked Ferric Cytochrome P450cam Mutant(D297L) 分子名称: CAMPHOR, Camphor 5-monooxygenase, POTASSIUM ION, ... 著者 Sakurai, K, Harada, K, Shimada, H, Shimokata, K, Hayashi, T, Tsukihara, T. 登録日 2008-10-18 公開日 2009-10-20 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Crystal Structure of Camphor-soaked Ferric Cytochrome P450cam Mutant to be published
4GTO	FTase in complex with BMS analogue 14 分子名称: 4-({(3R)-7-cyano-4-[(4-methoxyphenyl)sulfonyl]-1-[(1-methyl-1H-imidazol-5-yl)methyl]-2,3,4,5-tetrahydro-1H-1,4-benzodiazepin-3-yl}methyl)phenyl trifluoromethanesulfonate, DIMETHYL SULFOXIDE, FARNESYL DIPHOSPHATE, ... 著者 Guo, Z, Stigter, E.A, Bon, R.S, Waldmann, H, Blankenfeldt, W, Goody, R.S. 登録日 2012-08-29 公開日 2012-10-24 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Development of Selective, Potent RabGGTase Inhibitors J.Med.Chem., 55, 2012
1PMA	PROTEASOME FROM THERMOPLASMA ACIDOPHILUM 分子名称: PROTEASOME 著者 Loewe, J, Stock, D, Jap, B, Zwickl, P, Baumeister, W, Huber, R. 登録日 1994-12-19 公開日 1996-06-20 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (3.4 Å) 主引用文献 Crystal structure of the 20S proteasome from the archaeon T. acidophilum at 3.4 A resolution. Science, 268, 1995
4MB3	Crystal structure of E153Q mutant of cold-adapted chitinase from Moritella marina 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, CHLORIDE ION, Chitinase 60, ... 著者 Malecki, P.H, Vorgias, C.E, Rypniewski, W. 登録日 2013-08-19 公開日 2014-03-19 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Crystal structures of substrate-bound chitinase from the psychrophilic bacterium Moritella marina and its structure in solution Acta Crystallogr.,Sect.D, 70, 2014
3A26	Crystal structure of P. horikoshii TYW2 in complex with MeSAdo 分子名称: 5'-DEOXY-5'-METHYLTHIOADENOSINE, TETRAETHYLENE GLYCOL, Uncharacterized protein PH0793 著者 Umitsu, M, Nishimasu, H, Ishitani, R, Nureki, O. 登録日 2009-04-28 公開日 2009-09-15 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structural basis of AdoMet-dependent aminocarboxypropyl transfer reaction catalyzed by tRNA-wybutosine synthesizing enzyme, TYW2 Proc.Natl.Acad.Sci.USA, 106, 2009
6WF7	Methylmalonyl-CoA epimerase in complex with methylmalonyl-CoA and NH4+ 分子名称: (S)-Methylmalonyl-Coenzyme A, AMMONIUM ION, METHYLMALONYL-COENZYME A, ... 著者 Stunkard, L.M, Benjamin, A.B, Bower, J.B, Huth, T.J, Lohman, J.R. 登録日 2020-04-03 公開日 2020-07-08 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Substrate Enolate Intermediate and Mimic Captured in the Active Site of Streptomyces coelicolor Methylmalonyl-CoA Epimerase. Chembiochem, 23, 2022
4HME	Crystal structure of cold-adapted chitinase from Moritella marina with a reaction product - NAG2 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Chitinase 60, GLYCEROL, ... 著者 Malecki, P.H, Vorgias, C.E, Raczynska, J.E, Rypniewski, W. 登録日 2012-10-18 公開日 2013-05-01 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (2.07 Å) 主引用文献 Structure of a complete four-domain chitinase from Moritella marina, a marine psychrophilic bacterium Acta Crystallogr.,Sect.D, 69, 2013
4Q8R	Crystal structure of a Phosphate Binding Protein (PBP-1) from Clostridium perfringens 分子名称: PHOSPHATE ION, Phosphate ABC transporter, phosphate-binding protein, ... 著者 Gonzalez, D, Richez, M, Bergonzi, C, Chabriere, E, Elias, M. 登録日 2014-04-28 公開日 2014-11-05 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Crystal structure of the phosphate-binding protein (PBP-1) of an ABC-type phosphate transporter from Clostridium perfringens. Sci Rep, 4, 2014
4HNK	Crystal structure of an Enzyme 分子名称: ATP-dependent Clp protease proteolytic subunit, GLYCEROL 著者 El Bakkouri, M, Calmettes, C, Wernimont, A.K, Houry, W.A, Hui, R, Structural Genomics Consortium (SGC) 登録日 2012-10-19 公開日 2012-12-05 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Structural Insights into the Inactive Subunit of the Apicoplast-localized Caseinolytic Protease Complex of Plasmodium falciparum. J.Biol.Chem., 288, 2013
6WPP	HUMAN NIK IN COMPLEX WITH LIGAND COMPOUND X 分子名称: 5-fluoro-N-methyl-2-(7H-pyrrolo[2,3-d]pyrimidin-5-yl)pyrimidin-4-amine, Mitogen-activated protein kinase kinase kinase 14 著者 Shih, A.Y, Hack, M, Mirzadegan, T. 登録日 2020-04-27 公開日 2020-08-26 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.55 Å) 主引用文献 Impact of Protein Preparation on Resulting Accuracy of FEP Calculations. J.Chem.Inf.Model., 60, 2020
2ZWU	Crystal Structure of Camphor Soaked Ferric Cytochrome P450cam 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CAMPHOR, Camphor 5-monooxygenase, ... 著者 Sakurai, K, Shimada, H, Hayashi, T, Tsukihara, T. 登録日 2008-12-18 公開日 2009-02-17 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 Substrate binding induces structural changes in cytochrome P450cam Acta Crystallogr.,Sect.F, 65, 2009
4HR7	Crystal Structure of Biotin Carboxyl Carrier Protein-Biotin Carboxylase Complex from E.coli 分子名称: 1,2-ETHANEDIOL, Biotin carboxyl carrier protein of acetyl-CoA carboxylase, Biotin carboxylase, ... 著者 Broussard, T.C, Kobe, M.J, Pakhomova, S, Neau, D.B, Price, A.E, Champion, T.S, Waldrop, G.L. 登録日 2012-10-26 公開日 2013-03-13 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.495 Å) 主引用文献 The three-dimensional structure of the biotin carboxylase-biotin carboxyl carrier protein complex of E. coli acetyl-CoA carboxylase. Structure, 21, 2013
3A5C	Inter-subunit interaction and quaternary rearrangement defined by the central stalk of prokaryotic V1-ATPase 分子名称: ADENOSINE-5'-DIPHOSPHATE, V-type ATP synthase alpha chain, V-type ATP synthase beta chain, ... 著者 Numoto, N, Hasegawa, Y, Takeda, K, Miki, K. 登録日 2009-08-06 公開日 2009-10-13 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (4.51 Å) 主引用文献 Inter-subunit interaction and quaternary rearrangement defined by the central stalk of prokaryotic V1-ATPase Embo Rep., 10, 2009
2ZWT	Crystal Structure of Ferric Cytochrome P450cam 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CAMPHOR, Camphor 5-monooxygenase, ... 著者 Sakurai, K, Shimada, H, Hayashi, T, Tsukihara, T. 登録日 2008-12-18 公開日 2009-02-17 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.35 Å) 主引用文献 Substrate binding induces structural changes in cytochrome P450cam Acta Crystallogr.,Sect.F, 65, 2009
5F1A	The Crystal Structure of Salicylate Bound to Human Cyclooxygenase-2 分子名称: 1,2-ETHANEDIOL, 2-HYDROXYBENZOIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Lucido, M.J, Orlando, B.J, Malkowski, M.G. 登録日 2015-11-30 公開日 2016-03-16 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (2.38 Å) 主引用文献 Crystal Structure of Aspirin-Acetylated Human Cyclooxygenase-2: Insight into the Formation of Products with Reversed Stereochemistry. Biochemistry, 55, 2016
4MKB	Hepatitis C Virus polymerase NS5B genotype 1b (BK) in complex with inhibitor 14 (N-(4-{(E)-2-[3-tert-butyl-2-methoxy-5-(3-oxo-2,3-dihydropyridazin-4-yl)phenyl]ethenyl}phenyl)methanesulfonamide) 分子名称: N-(4-{(E)-2-[3-tert-butyl-2-methoxy-5-(3-oxo-2,3-dihydropyridazin-4-yl)phenyl]ethenyl}phenyl)methanesulfonamide, RNA-DIRECTED RNA POLYMERASE 著者 Harris, S.F, Wong, A. 登録日 2013-09-04 公開日 2013-10-09 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Discovery of a Novel Series of Potent Non-Nucleoside Inhibitors of Hepatitis C Virus NS5B. J.Med.Chem., 56, 2013
8FLS	Human PTH1R in complex with Abaloparatide and Gs 分子名称: Abaloparatide, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... 著者 Cary, B.P, Belousoff, M.J, Piper, S.J, Wootten, D, Sexton, P.M. 登録日 2022-12-22 公開日 2023-04-26 最終更新日 2023-06-14 実験手法 ELECTRON MICROSCOPY (3.09 Å) 主引用文献 Molecular insights into peptide agonist engagement with the PTH receptor. Structure, 31, 2023
8FLU	Human PTH1R in complex with LA-PTH and Gs 分子名称: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, ... 著者 Cary, B.P, Belousoff, M.J, Piper, S.J, Wootten, D, Sexton, P.M. 登録日 2022-12-22 公開日 2023-04-26 最終更新日 2024-10-16 実験手法 ELECTRON MICROSCOPY (2.76 Å) 主引用文献 Molecular insights into peptide agonist engagement with the PTH receptor. Structure, 31, 2023
8FLR	Human PTH1R in complex with PTHrP and Gs 分子名称: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, ... 著者 Cary, B.P, Belousoff, M.J, Piper, S.J, Wootten, D, Sexton, P.M. 登録日 2022-12-22 公開日 2023-04-26 最終更新日 2023-06-14 実験手法 ELECTRON MICROSCOPY (2.94 Å) 主引用文献 Molecular insights into peptide agonist engagement with the PTH receptor. Structure, 31, 2023

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