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7NW3
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X-ray crystallographic study of PIYDIN, which contains the truncation determinants of binding PI and N, bound to RoAb13, a CCR5 antibody
分子名称: Antibody RoAb13 Heavy Chain, Antibody RoAb13 Light Chain, Region from C-C chemokine receptor type 5 N-terminal domain
著者Saridakis, E, Helliwell, J.R, Govada, L, Chayen, N.E.
登録日2021-03-16
公開日2021-07-21
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (3.200011 Å)
主引用文献X-ray crystallographic studies of RoAb13 bound to PIYDIN, a part of the N-terminal domain of C-C chemokine receptor 5.
Iucrj, 8, 2021
8V4Y
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BU of 8v4y by Molmil
Cryo-EM structure of singly-bound SNF2h-nucleosome complex with SNF2h at inactive SHL2 (conformation 1)
分子名称: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, Histone H2A type 1, ...
著者Chio, U.S, Palovcak, E, Armache, J.P, Narlikar, G.J, Cheng, Y.
登録日2023-11-29
公開日2024-03-20
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Functionalized graphene-oxide grids enable high-resolution cryo-EM structures of the SNF2h-nucleosome complex without crosslinking.
Nat Commun, 15, 2024
8V6V
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Cryo-EM structure of doubly-bound SNF2h-nucleosome complex
分子名称: ADENOSINE-5'-DIPHOSPHATE, Histone H2A type 1, Histone H2B, ...
著者Chio, U.S, Palovcak, E, Armache, J.P, Narlikar, G.J, Cheng, Y.
登録日2023-12-03
公開日2024-03-20
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Functionalized graphene-oxide grids enable high-resolution cryo-EM structures of the SNF2h-nucleosome complex without crosslinking.
Nat Commun, 15, 2024
7AHU
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BU of 7ahu by Molmil
Anti-FX Fab of mim8 in complex with human FXa
分子名称: Anti-FX Fab of mim8 heavy chain, Anti-FX Fab of mim8 light chain, CALCIUM ION, ...
著者Johansson, E.
登録日2020-09-25
公開日2021-07-07
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献A factor VIIIa-mimetic bispecific antibody, Mim8, ameliorates bleeding upon severe vascular challenge in hemophilia A mice.
Blood, 138, 2021
6PMD
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BU of 6pmd by Molmil
Structure of ClpP from Staphylococcus aureus in complex with Acyldepsipeptide
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, ATP-dependent Clp protease proteolytic subunit, SHV-WFP-SER-PRO-YCP-ALA-MP8 Acyldepsipeptide
著者Griffith, E.C, Lee, R.E.
登録日2019-07-01
公開日2019-11-06
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.21 Å)
主引用文献Ureadepsipeptides as ClpP Activators.
Acs Infect Dis., 5, 2019
8FYM
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BU of 8fym by Molmil
Crystal structure of Fab235 in complex with MPER peptide
分子名称: ALA-SER-LEU-TRP-ASN-TRP-PHE-ASN-ILE-THR-ASN-TRP-LEU-TRP-TYR-ILE-LYS-LYS-LYS, CHLORIDE ION, Fab235, ...
著者Tan, K, Kim, M, Reinherz, E.L.
登録日2023-01-26
公開日2023-10-11
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Inadequate structural constraint on Fab approach rather than paratope elicitation limits HIV-1 MPER vaccine utility.
Nat Commun, 14, 2023
6PLH
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BU of 6plh by Molmil
FAB fragment complexed with C-mannosylated tryptophan peptide
分子名称: Fab 5G12 heavy chain, Fab 5G12 light chain, Interleukin-21 receptor, ...
著者John, A, Jarva, M.A, Goddard-Borger, E.D.
登録日2019-06-30
公開日2020-07-08
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Yeast- and antibody-based tools for studying tryptophan C-mannosylation.
Nat.Chem.Biol., 17, 2021
8FAN
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BU of 8fan by Molmil
Crystal structure of Ky15.1 Fab in complex with circumsporozoite protein KQPA peptide
分子名称: Circumsporozoite protein KQPA peptide, Ky15.1 Antibody, heavy chain, ...
著者Burn Aschner, C, Thai, E, Julien, J.P.
登録日2022-11-28
公開日2023-11-01
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Molecular determinants of cross-reactivity and potency by VH3-33 antibodies against the Plasmodium falciparum circumsporozoite protein.
Cell Rep, 42, 2023
8F9V
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Crystal structure of Ky15.8 Fab in complex with circumsporozoite protein KQPA peptide
分子名称: 1,2-ETHANEDIOL, Circumsporozoite protein KQPA peptide, Ky15.8 Antibody, ...
著者Thai, E, Prieto, K, Julien, J.P.
登録日2022-11-24
公開日2023-11-01
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Molecular determinants of cross-reactivity and potency by VH3-33 antibodies against the Plasmodium falciparum circumsporozoite protein.
Cell Rep, 42, 2023
7QD1
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Structure of the orange carotenoid protein from Planktothrix agardhii binding echinenone in the P21 space group
分子名称: Orange carotenoid-binding protein, beta,beta-caroten-4-one
著者Andreeva, E.A, Hartmann, E, Schlichting, I, Colletier, J.-P.
登録日2021-11-26
公開日2022-07-06
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.71 Å)
主引用文献Structure-function-dynamics relationships in the peculiar Planktothrix PCC7805 OCP1: Impact of his-tagging and carotenoid type.
Biochim Biophys Acta Bioenerg, 1863, 2022
8F9W
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BU of 8f9w by Molmil
Crystal structure of Ky15.8 Fab in complex with circumsporozoite protein NPDP peptide
分子名称: 1,2-ETHANEDIOL, Circumsporozoite protein NPDP peptide, Ky15.8 Antibody, ...
著者Thai, E, Prieto, K, Julien, J.P.
登録日2022-11-24
公開日2023-11-01
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Molecular determinants of cross-reactivity and potency by VH3-33 antibodies against the Plasmodium falciparum circumsporozoite protein.
Cell Rep, 42, 2023
7QD0
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BU of 7qd0 by Molmil
Structure of the orange carotenoid protein from Planktothrix agardhii binding echinenone in the C2 space group
分子名称: ACETATE ION, ARGININE, GLYCEROL, ...
著者Andreeva, E.A, Hartmann, E, Schlichting, I, Colletier, J.-P.
登録日2021-11-25
公開日2022-07-06
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structure-function-dynamics relationships in the peculiar Planktothrix PCC7805 OCP1: Impact of his-tagging and carotenoid type.
Biochim Biophys Acta Bioenerg, 1863, 2022
7QD2
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BU of 7qd2 by Molmil
Structure of the orange carotenoid protein from Planktothrix agardhii binding canthaxanthin in the P21 space group
分子名称: ACETATE ION, GLYCEROL, Orange carotenoid-binding protein, ...
著者Andreeva, E.A, Hartmann, E, Schlichting, I, Colletier, J.-P.
登録日2021-11-26
公開日2022-07-06
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Structure-function-dynamics relationships in the peculiar Planktothrix PCC7805 OCP1: Impact of his-tagging and carotenoid type.
Biochim Biophys Acta Bioenerg, 1863, 2022
4YJN
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BU of 4yjn by Molmil
Calcium-Dependent Protein Kinase 1 from Toxoplasma gondii (TgCDPK1) in complex with inhibitor UW1639
分子名称: 5-amino-1-tert-butyl-3-[2-(cyclobutyloxy)quinolin-6-yl]-1H-pyrazole-4-carboxamide, Calmodulin-domain protein kinase 1
著者Merritt, E.A.
登録日2015-03-03
公開日2015-11-25
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献SAR Studies of 5-Aminopyrazole-4-carboxamide Analogues as Potent and Selective Inhibitors of Toxoplasma gondii CDPK1.
Acs Med.Chem.Lett., 6, 2015
7ANM
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BU of 7anm by Molmil
Nudaurelia capensis omega virus capsid: virus-like particles expressed in Nicotiana benthamiana
分子名称: p70
著者Castells-Graells, R, Ribeiro, J.R.S, Domitrovic, T, Hesketh, E.L, Scarff, C.A, Johnson, J.E, Ranson, N.A, Lawson, D.M, Lomonossoff, G.P.
登録日2020-10-12
公開日2021-08-25
最終更新日2024-07-10
実験手法ELECTRON MICROSCOPY (2.72 Å)
主引用文献Plant-expressed virus-like particles reveal the intricate maturation process of a eukaryotic virus.
Commun Biol, 4, 2021
7O3U
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BU of 7o3u by Molmil
The crystal structure of obelin from Obelia longissima bound with v-coelenterazine
分子名称: CALCIUM ION, Obelin, v-coelenterazine
著者Larionova, M.D, Wu, L.J, Vysotski, E.S, Liu, Z.-J.
登録日2021-04-03
公開日2022-02-09
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal structure of semisynthetic obelin-v.
Protein Sci., 31, 2022
7ATA
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BU of 7ata by Molmil
Nudaurelia capensis omega virus procapsid: virus-like particles expressed in Nicotiana benthamiana
分子名称: p70
著者Castells-Graells, R, Ribeiro, J.R.S, Domitrovic, T, Hesketh, E.L, Scarff, C.A, Johnson, J.E, Ranson, N.A, Lawson, D.M, Lomonossoff, G.P.
登録日2020-10-29
公開日2021-08-25
実験手法ELECTRON MICROSCOPY (6.63 Å)
主引用文献Plant-expressed virus-like particles reveal the intricate maturation process of a eukaryotic virus.
Commun Biol, 4, 2021
6PRU
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BU of 6pru by Molmil
Photoconvertible crystals of PixJ from Thermosynechococcus elongatus
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ...
著者Burgie, E.S, Clinger, J.A, Miller, M.D, Phillips Jr, G.N, Vierstra, R.D.
登録日2019-07-11
公開日2019-12-18
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.539 Å)
主引用文献Photoreversible interconversion of a phytochrome photosensory module in the crystalline state.
Proc.Natl.Acad.Sci.USA, 117, 2020
8FF3
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BU of 8ff3 by Molmil
Amyloid-beta (1-40) fibrils derived from familial Dutch-type CAA patient (population B)
分子名称: Amyloid-beta precursor protein
著者Crooks, E.J, Fu, Z, Chowdury, S, Smith, S.O.
登録日2022-12-07
公開日2023-12-06
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (3.09 Å)
主引用文献An electrostatic cluster guides A beta 40 fibril formation in sporadic and Dutch-type cerebral amyloid angiopathy.
J.Struct.Biol., 216, 2024
7QEI
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BU of 7qei by Molmil
Structure of human MTHFD2L in complex with TH7299
分子名称: (2S)-2-[[4-[[2,4-bis(azanyl)-6-oxidanylidene-1H-pyrimidin-5-yl]carbamoylamino]phenyl]carbonylamino]pentanedioic acid, 2'-MONOPHOSPHOADENOSINE-5'-DIPHOSPHATE, Probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2
著者Gustafsson, R, Scaletti, E.R, Stenmark, P.
登録日2021-12-03
公開日2022-10-12
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献The First Structure of Human MTHFD2L and Its Implications for the Development of Isoform-Selective Inhibitors.
Chemmedchem, 17, 2022
8R1C
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BU of 8r1c by Molmil
SD1-2 Fab in complex with SARS-CoV-2 BA.2.12.1 Spike Glycoprotein
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, SD1-2 fab heavy chain, SD1-2 fab light chain, ...
著者Duyvesteyn, H.M.E, Ren, J, Stuart, D.I.
登録日2023-11-01
公開日2024-03-13
最終更新日2024-04-10
実験手法ELECTRON MICROSCOPY (2.2 Å)
主引用文献The SARS-CoV-2 neutralizing antibody response to SD1 and its evasion by BA.2.86.
Nat Commun, 15, 2024
8ITN
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BU of 8itn by Molmil
Crystal structure of USP47apo catalytic domain
分子名称: Ubiquitin carboxyl-terminal hydrolase 47, ZINC ION
著者Kim, E.E, Shin, S.C.
登録日2023-03-22
公開日2024-03-27
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural and functional characterization of USP47 reveals a hot spot for inhibitor design.
Commun Biol, 6, 2023
8ITP
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Crystal structure of USP47 catalytic domain complex with ubiquitin
分子名称: Ubiquitin, Ubiquitin carboxyl-terminal hydrolase 47, ZINC ION
著者Kim, E.E, Shin, S.C.
登録日2023-03-22
公開日2024-03-27
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural and functional characterization of USP47 reveals a hot spot for inhibitor design.
Commun Biol, 6, 2023
1FUN
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BU of 1fun by Molmil
SUPEROXIDE DISMUTASE MUTANT WITH LYS 136 REPLACED BY GLU, CYS 6 REPLACED BY ALA AND CYS 111 REPLACED BY SER (K136E, C6A, C111S)
分子名称: COPPER (II) ION, SULFATE ION, SUPEROXIDE DISMUTASE, ...
著者Lo, T.P, Tainer, J.A, Getzoff, E.D.
登録日1998-07-23
公開日1999-07-23
最終更新日2021-11-03
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Computational, pulse-radiolytic, and structural investigations of lysine-136 and its role in the electrostatic triad of human Cu,Zn superoxide dismutase.
Proteins, 29, 1997
6YCL
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BU of 6ycl by Molmil
Crystal structure of GcoA T296G bound to p-vanillin
分子名称: 4-hydroxy-3-methoxybenzaldehyde, Aromatic O-demethylase, cytochrome P450 subunit, ...
著者Hinchen, D.J, Mallinson, S.J.B, Allen, M.D, Ellis, E.S, Beckham, G.T, DuBois, J.L, McGeehan, J.E.
登録日2020-03-18
公開日2021-02-17
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Engineering a Cytochrome P450 for Demethylation of Lignin-Derived Aromatic Aldehydes.
Jacs Au, 1, 2021

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件を2024-08-14に公開中

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