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4ZY2
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X-ray crystal structure of PfA-M17 in complex with hydroxamic acid-based inhibitor 10o
分子名称: CARBONATE ION, DIMETHYL SULFOXIDE, N-[(1R)-2-(hydroxyamino)-2-oxo-1-(3',4',5'-trifluorobiphenyl-4-yl)ethyl]-2,2-dimethylpropanamide, ...
著者Drinkwater, N, McGowan, S.
登録日2015-05-21
公開日2016-03-30
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Potent dual inhibitors of Plasmodium falciparum M1 and M17 aminopeptidases through optimization of S1 pocket interactions.
Eur.J.Med.Chem., 110, 2016
1VQM
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BU of 1vqm by Molmil
The structure of the transition state analogue "DAN" bound to the large ribosomal subunit of haloarcula marismortui
分子名称: 23S ribosomal rna, 5'-R(*CP*CP*(PPU)P*(PO2)P*(DA)P*C*C)-3'), 50S RIBOSOMAL PROTEIN L10E, ...
著者Schmeing, T.M, Steitz, T.A.
登録日2004-12-16
公開日2005-11-29
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural Insights into the Roles of Water and the 2' Hydroxyl of the P Site tRNA in the Peptidyl Transferase Reaction.
Mol.Cell, 20, 2005
5AFI
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BU of 5afi by Molmil
2.9A Structure of E. coli ribosome-EF-TU complex by cs-corrected cryo-EM
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Fischer, N, Neumann, P, Konevega, A.L, Bock, L.V, Ficner, R, Rodnina, M.V, Stark, H.
登録日2015-01-22
公開日2015-03-11
最終更新日2024-04-24
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Structure of the E. coli ribosome-EF-Tu complex at <3 angstrom resolution by Cs-corrected cryo-EM.
Nature, 520, 2015
5AII
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BU of 5aii by Molmil
Discovery and characterization of thermophilic limonene-1,2-epoxide hydrolases from hot spring metagenomic libraries. CH55-sample-PEG complex
分子名称: 1,2-ETHANEDIOL, 1-(2-METHOXY-ETHOXY)-2-{2-[2-(2-METHOXY-ETHOXY]-ETHOXY}-ETHANE, 1-METHOXY-2-[2-(2-METHOXY-ETHOXY]-ETHANE, ...
著者Ferrandi, E, Sayer, C, Isupov, M.N, Annovazzi, C, Marchesi, C, Iacobone, G, Peng, X, Bonch-Osmolovskaya, E, Wohlgemuth, R, Littlechild, J.A, Montia, D.
登録日2015-02-13
公開日2015-06-17
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.47 Å)
主引用文献Discovery and Characterization of Thermophilic Limonene-1,2-Epoxide Hydrolases from Hot Spring Metagenomic Libraries
FEBS J., 282, 2015
1XMO
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BU of 1xmo by Molmil
Crystal Structure of mnm5U34t6A37-tRNALysUUU Complexed with AAG-mRNA in the Decoding Center
分子名称: 16S ribosomal RNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ...
著者Murphy, F.V, Ramakrishnan, V, Malkiewicz, A, Agris, P.F.
登録日2004-10-04
公開日2004-12-14
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (3.25 Å)
主引用文献The role of modifications in codon discrimination by tRNA(Lys)(UUU).
Nat.Struct.Mol.Biol., 11, 2004
3H6I
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BU of 3h6i by Molmil
Crystal Structure of Mycobacterium Tuberculosis Proteasome Modified by inhibitor GL1
分子名称: DIMETHYLFORMAMIDE, Proteasome (Alpha subunit) PrcA, Proteasome (Beta subunit) PrcB
著者Li, D, Li, H, Lin, G.
登録日2009-04-23
公開日2009-09-15
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.43 Å)
主引用文献Inhibitors selective for mycobacterial versus human proteasomes.
Nature, 461, 2009
1V54
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Bovine heart cytochrome c oxidase at the fully oxidized state
分子名称: (1R)-2-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL (11E)-OCTADEC-11-ENOATE, (1S)-2-{[(2-AMINOETHOXY)(HYDROXY)PHOSPHORYL]OXY}-1-[(STEAROYLOXY)METHYL]ETHYL (5E,8E,11E,14E)-ICOSA-5,8,11,14-TETRAENOATE, (7R,17E,20E)-4-HYDROXY-N,N,N-TRIMETHYL-9-OXO-7-[(PALMITOYLOXY)METHYL]-3,5,8-TRIOXA-4-PHOSPHAHEXACOSA-17,20-DIEN-1-AMINIUM 4-OXIDE, ...
著者Tsukihara, T, Shimokata, K, Katayama, Y, Shimada, H, Muramoto, K, Aoyama, H, Mochizuki, M, Shinzawa-Itoh, K, Yamashita, E, Yao, M, Ishimura, Y, Yoshikawa, S.
登録日2003-11-21
公開日2003-12-23
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献The low-spin heme of cytochrome c oxidase as the driving element of the proton-pumping process.
Proc.Natl.Acad.Sci.Usa, 100, 2003
5AJ0
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BU of 5aj0 by Molmil
Cryo electron microscopy of actively translating human polysomes (POST state).
分子名称: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ...
著者Behrmann, E, Loerke, J, Budkevich, T.V, Yamamoto, K, Schmidt, A, Penczek, P.A, Vos, M.R, Burger, J, Mielke, T, Scheerer, P, Spahn, C.M.T.
登録日2015-02-19
公開日2015-05-20
最終更新日2019-12-18
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Structural Snapshots of Actively Translating Human Ribosomes
Cell(Cambridge,Mass.), 161, 2015
5AKA
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BU of 5aka by Molmil
EM structure of ribosome-SRP-FtsY complex in closed state
分子名称: 23S ribosomal RNA, 4.5S ribosomal RNA, 50S RIBOSOMAL PROTEIN L11, ...
著者von Loeffelholz, O, Jiang, Q, Ariosa, A, Karuppasamy, M, Huard, K, Berger, I, Shan, S, Schaffitzel, C.
登録日2015-03-03
公開日2015-03-25
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (5.7 Å)
主引用文献Ribosome-Srp-Ftsy Cotranslational Targeting Complex in the Closed State.
Proc.Natl.Acad.Sci.USA, 112, 2015
1VQK
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BU of 1vqk by Molmil
The structure of CCDA-PHE-CAP-BIO bound to the a site of the ribosomal subunit of haloarcula marismortui
分子名称: 23S ribosomal rna, 5'-R(*CP*CP*(DA)*(PHE)*(ACA))-3', 50S RIBOSOMAL PROTEIN L10E, ...
著者Schmeing, T.M, Steitz, T.A.
登録日2004-12-16
公開日2005-11-29
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural Insights into the Roles of Water and the 2' Hydroxyl of the P Site tRNA in the Peptidyl Transferase Reaction.
Mol.Cell, 20, 2005
1VY6
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BU of 1vy6 by Molmil
Crystal structure of the Thermus thermophilus 70S ribosome in the pre-attack state of peptide bond formation containing short substrate-mimic Cytidine-Puromycin in the A site and acylated tRNA in the P site.
分子名称: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ...
著者Polikanov, Y.S, Steitz, T.A, Innis, C.A.
登録日2014-05-13
公開日2014-08-20
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献A proton wire to couple aminoacyl-tRNA accommodation and peptide-bond formation on the ribosome.
Nat.Struct.Mol.Biol., 21, 2014
1VQL
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BU of 1vql by Molmil
The structure of the transition state analogue "DCSN" bound to the large ribosomal subunit of haloarcula marismortui
分子名称: 23S ribosomal rna, 5'-R(*CP*CP*(PPU)*(TSE)*(DA)*CP*C)-3', 50S RIBOSOMAL PROTEIN L10E, ...
著者Schmeing, T.M, Steitz, T.A.
登録日2004-12-16
公開日2005-11-29
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural Insights into the Roles of Water and the 2' Hydroxyl of the P Site tRNA in the Peptidyl Transferase Reaction.
Mol.Cell, 20, 2005
1W2B
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BU of 1w2b by Molmil
Trigger Factor ribosome binding domain in complex with 50S
分子名称: 23S RRNA, 50S RIBOSOMAL PROTEIN L10E, 50S RIBOSOMAL PROTEIN L13P, ...
著者Ferbitz, L, Maier, T, Patzelt, H, Bukau, B, Deuerling, E, Ban, N.
登録日2004-07-01
公開日2004-09-02
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Trigger Factor in Complex with the Ribosome Forms a Molecular Cradle for Nascent Proteins
Nature, 431, 2004
1VQP
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The structure of the transition state analogue "RAP" bound to the large ribosomal subunit of haloarcula marismortui
分子名称: 23S ribosomal rna, 5'-R(*(DC)P*(DC)P*(PPU)*(LOF)P*(PO2)P*AP*C*C)-3', 50S RIBOSOMAL PROTEIN L10E, ...
著者Schmeing, T.M, Steitz, T.A.
登録日2004-12-16
公開日2005-11-29
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Structural Insights into the Roles of Water and the 2' Hydroxyl of the P Site tRNA in the Peptidyl Transferase Reaction.
Mol.Cell, 20, 2005
4YHH
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BU of 4yhh by Molmil
Crystal structure of the 30S ribosomal subunit from Thermus thermophilus in complex with tigecycline
分子名称: 16S ribosomal RNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ...
著者Schedlbauer, A, Kaminishi, T, Ochoa-Lizarralde, B, Dhimole, N, Zhou, S, Lopez-Alonso, J.P, Connell, S.R, Fucini, P.
登録日2015-02-27
公開日2015-04-08
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (3.417 Å)
主引用文献Structural characterization of an alternative mode of tigecycline binding to the bacterial ribosome.
Antimicrob.Agents Chemother., 59, 2015
1VY4
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BU of 1vy4 by Molmil
Crystal structure of the Thermus thermophilus 70S ribosome in the pre-attack state of peptide bond formation containing acylated tRNA-substrates in the A and P sites.
分子名称: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ...
著者Polikanov, Y.S, Steitz, T.A, Innis, C.A.
登録日2014-05-13
公開日2014-08-20
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献A proton wire to couple aminoacyl-tRNA accommodation and peptide-bond formation on the ribosome.
Nat.Struct.Mol.Biol., 21, 2014
3HF9
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BU of 3hf9 by Molmil
Crystal Structure of Mycobacterium Tuberculosis Proteasome open-gate mutant modified by inhibitor GL1
分子名称: Proteasome (Alpha subunit) PrcA, Proteasome (Beta subunit) PrcB
著者Li, D, Li, H.
登録日2009-05-11
公開日2009-09-15
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.878 Å)
主引用文献Inhibitors selective for mycobacterial versus human proteasomes.
Nature, 461, 2009
1XNQ
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BU of 1xnq by Molmil
Structure of an Inosine-Adenine Wobble Base Pair Complex in the Context of the Decoding Center
分子名称: 16S ribosomal RNA, Anticodon tRNA, MAGNESIUM ION, ...
著者Murphy, F.V, Ramakrishnan, V.
登録日2004-10-05
公開日2004-12-14
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (3.05 Å)
主引用文献Structure of a purine-purine wobble base pair in the decoding center of the ribosome.
Nat.Struct.Mol.Biol., 11, 2004
1UW9
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L290F-A222T chlamydomonas Rubisco mutant
分子名称: 1,2-ETHANEDIOL, 2-CARBOXYARABINITOL-1,5-DIPHOSPHATE, MAGNESIUM ION, ...
著者Karkehabadi, S, Taylor, T.C, Spreitzer, R.J, Andersson, I.
登録日2004-02-03
公開日2005-01-12
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Altered Intersubunit Interactions in Crystal Structures of Catalytically Compromised Ribulose-1,5-Bisphosphate Carboxylase/Oxygenase
Biochemistry, 44, 2005
5B5M
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BU of 5b5m by Molmil
Crystal structure of the Sr-substituted LH1-RC complex from Tch. tepidum
分子名称: (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, BACTERIOCHLOROPHYLL A, BACTERIOPHEOPHYTIN A, ...
著者Wang-Otomo, Z.-Y, Yu, L.-J.
登録日2016-05-12
公開日2017-03-22
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Structural Basis for the Unusual Qy Red-Shift and Enhanced Thermostability of the LH1 Complex from Thermochromatium tepidum.
Biochemistry, 55, 2016
1UZH
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A CHIMERIC CHLAMYDOMONAS, SYNECHOCOCCUS RUBISCO ENZYME
分子名称: 1,2-ETHANEDIOL, 2-CARBOXYARABINITOL-1,5-DIPHOSPHATE, MAGNESIUM ION, ...
著者Karkehabadi, S, Spreitzer, R.J, Andersson, I.
登録日2004-03-12
公開日2005-05-31
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Chimeric Small Subunits Influence Catalysis without Causing Global Conformational Changes in the Crystal Structure of Ribulose-1,5-Bisphosphate Carboxylase/Oxygenase
Biochemistry, 44, 2005
5APO
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BU of 5apo by Molmil
Structure of the yeast 60S ribosomal subunit in complex with Arx1, Alb1 and C-terminally tagged Rei1
分子名称: 25S ribosomal RNA, 5.8S ribosomal RNA, 5S ribosomal RNA, ...
著者Greber, B.J, Gerhardy, S, Leitner, A, Leibundgut, M, Salem, M, Boehringer, D, Leulliot, N, Aebersold, R, Panse, V.G, Ban, N.
登録日2015-09-17
公開日2015-12-16
最終更新日2019-12-18
実験手法ELECTRON MICROSCOPY (3.41 Å)
主引用文献Insertion of the Biogenesis Factor Rei1 Probes the Ribosomal Tunnel during 60S Maturation.
Cell(Cambridge,Mass.), 164, 2016
3HQP
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BU of 3hqp by Molmil
Crystal structure of Leishmania mexicana pyruvate kinase (LmPYK) in complex with ATP, Oxalate and fructose 2,6 bisphosphate
分子名称: 2,6-di-O-phosphono-beta-D-fructofuranose, ADENOSINE-5'-TRIPHOSPHATE, GLYCEROL, ...
著者Morgan, H.P, Walkinshaw, M.D.
登録日2009-06-08
公開日2010-02-16
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献The allosteric mechanism of pryuvate kinase from Leishmania mexicana: a rock and lock model
J.Biol.Chem., 285, 2010
1V55
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Bovine heart cytochrome c oxidase at the fully reduced state
分子名称: (1R)-2-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL (11E)-OCTADEC-11-ENOATE, (1S)-2-{[(2-AMINOETHOXY)(HYDROXY)PHOSPHORYL]OXY}-1-[(STEAROYLOXY)METHYL]ETHYL (5E,8E,11E,14E)-ICOSA-5,8,11,14-TETRAENOATE, (7R,17E,20E)-4-HYDROXY-N,N,N-TRIMETHYL-9-OXO-7-[(PALMITOYLOXY)METHYL]-3,5,8-TRIOXA-4-PHOSPHAHEXACOSA-17,20-DIEN-1-AMINIUM 4-OXIDE, ...
著者Tsukihara, T, Shimokata, K, Katayama, Y, Shimada, H, Muramoto, K, Aoyama, H, Mochizuki, M, Shinzawa-Itoh, K, Yamashita, E, Yao, M, Ishimura, Y, Yoshikawa, S.
登録日2003-11-21
公開日2003-12-23
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献The low-spin heme of cytochrome c oxidase as the driving element of the proton-pumping process.
Proc.Natl.Acad.Sci.Usa, 100, 2003
1UZD
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Chlamydomonas,Spinach Chimeric Rubisco
分子名称: 1,2-ETHANEDIOL, 2-CARBOXYARABINITOL-1,5-DIPHOSPHATE, MAGNESIUM ION, ...
著者Karkehabadi, S, Spreitzer, R.J, Andersson, I.
登録日2004-03-11
公開日2005-05-31
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Chimeric Small Subunits Influence Catalysis without Causing Global Conformational Changes in the Crystal Structure of Ribulose-1,5-Bisphosphate Carboxylase/Oxygenase
Biochemistry, 44, 2005

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